CN104436123A

CN104436123A - Medicine for treatment ascariasis and preparation method thereof

Info

Publication number: CN104436123A
Application number: CN201410679523.3A
Authority: CN
Inventors: 蒋学
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-11-25
Filing date: 2014-11-25
Publication date: 2015-03-25

Abstract

The invention discloses a medicine for treating ascariasis and a preparation method thereof. The medicine is mainly prepared from the following raw materials according to a certain weight proportion: smoked plums, Chinese prickly ash, magnolia bark, cortex meliae, stone-like omphalia, lotus stamen, evodia rutaecarpa, artemisia apiacea, artemisia capillaris, and rhubarb. The medicine disclosed by the invention has the functions of converging and promoting the secretion of saliva or body fluid, warming spleen and stomach for dispelling cold, clearing away heat and toxic materials, removing food retention and killing parasite, and can be used for treating ascariasis with quick effect and good curative effect; the ascariasis cannot be recurred after treatment.

Description

A kind of medicine for the treatment of ascariasis and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of ascariasis and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Ascarid nematicide is called for short ascarid, is one of modal parasite in human body.Adult parasitizes small intestinal, can cause ascariasis.In addition, Toxocara canis (abbreviation ascaris alata) is the common Enterozoa of dog class, and its larva at human body internal migration, can cause visceral larva migrans.At present, because Western medicine effectively cannot treat ascariasis, and long-term taking Western medicine has more side effect, and therefore, people exist very large demand to the Chinese medicine of effectively treating ascariasis.

Summary of the invention

The present inventor, through research and experiment repeatedly, finally have found the medicine of effectively treatment ascariasis, thus completes the present invention.

Object of the present invention is just to provide a kind of composition of medicine effectively can treating ascariasis.

Another object of the present invention just there is provided the preparation method of this composition of medicine.

Medicine of the present invention selects Fructus Mume, Pericarpium Zanthoxyli, Cortex Magnoliae Officinalis, Cortex Meliae, Omphalia, Stamen Nelumbinis, Fructus Evodiae, Herba Artemisiae Annuae, Herba Artemisiae Scopariae, Radix Et Rhizoma Rhei, Rhizoma Coptidis, Radix Glycyrrhizae, Semen Arecae, Fructus Aurantii, Fructus Quisqualis, Herba Polygoni Avicularis, Flos Rosae Laevigatae, Radix Scutellariae, Ramulus Cinnamomi, Rhizoma Corydalis, Radix Angelicae Sinensis, Pseudobulbus cremastrae seu pleiones, Rhizoma Osmundae, Herba Asari, Cortex Phellodendri, Rhizoma Zingiberis, Rhizoma Atractylodis Macrocephalae medicine to combine; made by these drug regimens each efficacy of drugs produce synergism, thus can effectively treat ascarid palindromia.Fructus Mume is wherein selected to be that temperature, enter liver, spleen, lung, large intestine channel, have convergence to promote the production of body fluid, the function of relieving colic caused by ascaris anthelmintic, controls chronic cough, deficiency-heat excessive thirst, chronic malaria, and dysentery, has blood in stool, hematuria, metrorrhagia, and the ascariasis of biliary tract is suffered from abdominal pain, vomiting, ancylostomiasis, psoriasis, bulbar conjunctiva polyp because its nature and flavor acid.Pericarpium Zanthoxyli is selected to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, lung, kidney channel, have warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, separate fish raw meat poison, control food stagnation and stop drink, trusted subordinate's cold type of pain, vomiting, oh, cough with dyspnea, anemofrigid-damp arthralgia, has loose bowels, dysentery, colic, toothache, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies.Select Cortex Magnoliae Officinalis to be because its nature and flavor toil, temperature, enter spleen, stomach, large intestine channel, have warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, dampness, the function of expectorant, control breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, cold-damp dysentery.Cortex Meliae is selected to be that cold, poisonous, have heat clearing away, dampness, the function of parasite killing, controls ascarid, pinworm, rubella, scabies because its nature and flavor are bitter.Omphalia is selected to be that cold, slightly poisonous, enter stomach, large intestine channel, have removing food stagnancy, the function of parasite killing, controls abdominal pain due to worm stagnation, infantile malnutrition ， Feng Epilepsy because its nature and flavor are bitter.Stamen Nelumbinis is selected to be because its property sweet-puckery flavor, flat, enter the heart, kidney channel, have and clear away heart-fire, kidney tonifying, arresting seminal emission, the function of hemostasis, control nocturnal emission lingering diarrhea, tell, be defeated in battle, collapse, be with, dysentery.Select Fructus Evodiae to be because its nature and flavor are worked hard, temperature, poisonous, enter liver, stomach warp, have warming middle-JIAO, pain relieving, regulate the flow of vital energy, the function of dampness, stopping vomiting is against acid regurgitation, and headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.Herba Artemisiae Annuae is selected to be because its nature and flavor are bitter, micro-pungent, cold, be included into liver, gallbladder meridian, have heat clearing away, expelling summer-heat, except the function of steaming, control epidemic febrile disease, summer-heat, hectic fever due to YIN-deficiency consumptive fever, scabies, pruritus.Herba Artemisiae Scopariae is selected to be because its nature and flavor toil, cool, enter liver, spleen, urinary bladder channel, have the function of clearing away heat-damp and promoting diuresis, control jaundice due to damp-heat, dysuria, pruritus due to wind pathogen skin ulcer scabies.Radix Et Rhizoma Rhei is selected to be that enter stomach, large intestine, liver footpath, have the poison that purges heat, removing mass is stagnant because its nature and flavor are bitter, cold, the function of clots absorbing blood, control excess-heat constipation, delirium is gone mad, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinates red, carbuncle and ulcer toxic swelling, furuncle, burn.Rhizoma Coptidis is selected to be because its nature and flavor are bitter, cold, enter the heart, liver, stomach, large intestine channel, have pathogenic fire purging, dampness, removing toxic substances, the function of parasite killing, row pyretic toxicity, typhoid fever when controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, pulmonary tuberculosis, tells, is defeated in battle, hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Select Radix Glycyrrhizae Preparata to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, controls weakness of the spleen and stomach, lack of appetite, stomachache loose stool, and overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle.Select Semen Arecae to be because its nature and flavor toil, temperature, enters spleen, stomach, large intestine channel, has parasite killing, removing mass, the therapeutic method to keep the adverse QI flowing downwards, the function of row water, control malnutrition due to parasitic infestation, dyspepsia, abdominal distention, and heavy after dysentery, malaria, edema, beriberi, accumulation of phlegm in the hypochondrium ， Disorder ties.Fructus Aurantii is selected to be because its nature and flavor toil, cool.Enter lung, spleen, large intestine channel.Dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.Select Fructus Quisqualis to be because its nature and flavor are sweet, temperature, poisonous, enter spleen, stomach warp, have parasite killing, removing food stagnancy, the function of spleen invigorating, control ascarid stomachache, infantile malnutrition, breast food is stagnated, abdominal distention, dysentery.Choosing Herba Polygoni Avicularis is because its nature and flavor are bitter, cold, and enter urinary bladder channel, have diuresis, heat clearing away, the function of parasite killing, control pyretic stranguria, the difficulty in urination, jaundice, the erosion of the vulva, leucorrhea, ascarid, infantile malnutrition, hemorrhoid swell, eczema.Select Flos Rosae Laevigatae to be because its nature and flavor acid is flat, have the function of only cold and hot dysentery, kill cun white a, ascarid.Radix Scutellariae is selected to be because its nature and flavor are bitter, cold, enter the heart, lung, gallbladder, large intestine channel, have removing the relative excess fire, except damp and hot, hemostasis, antiabortive function, controls high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tells, is defeated in battle, collapses, leaks, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.Select Ramulus Cinnamomi to be because its property acrid-sweet flavor, temperature, enter bladder, the heart, lung meridian, have diaphoresis expelling pathogenic factors from muscles, the function of warming the meridian and promoting blood circulation, controls exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Rhizoma Corydalis is selected to be that temperature, enter liver, stomach warp, invigorate blood circulation, dissipating blood stasis, regulates the flow of vital energy, the function of pain relieving, controls all pains of trusted subordinate's waist knee joint, menoxenia ， mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury because its nature and flavor are worked hard.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Pseudobulbus cremastrae seu pleiones to be because its nature and flavor are sweet micro-pungent, cold, enter liver, spleen channel, have detumescence, eliminating stagnation, reduce phlegm, the function of removing toxic substances, control carbuncle furuncle and swell, scrofula, sore throat swells and ache, Serpentis, worm, mad dog wound.Select Rhizoma Osmundae to be because its nature and flavor are bitter, cool, enter liver, stomach warp, kill ascarid, silk ribbon, pinworm, heat clearing away, removing toxic substances, removing heat from blood, the function of hemostasis, controls anemopyretic cold, damp and hot skin eruption, spits blood, epistaxis, discharging fresh blood stool, dysentery, metrorrhagia, leukorrhagia.Select Herba Asari to be that temperature, enters lung, kidney channel, dispel the wind, cold expelling, row water because its nature and flavor are pungent, open the function of stealing, control air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Cortex Phellodendri is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Rhizoma Zingiberis to be that heat, enters spleen, stomach, lung meridian because its nature and flavor are pungent, have warming middle-JIAO by cold, the function that recuperating depleted YANG is promoted blood circulation, controls trusted subordinate's cold type of pain, vomits and diarrhoea, cold extremities faint pulse, and cold fluid-retention is breathed with cough, anemofrigid-damp arthralgia, and yang deficiency is told, be defeated in battle, hematochezia.Select the Rhizoma Atractylodis Macrocephalae to be because its property bitter but sweet flavor, temperature, enters spleen, stomach warp, has spleen reinforcing, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizzy, spontaneous perspiration, and nausea is uneasy.

Detailed description of the invention

The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight

Fructus Mume 9-14 gram of Pericarpium Zanthoxyli 2-7 gram Cortex Magnoliae Officinalis 6-10 gram

Cortex Meliae 10-15 Cray ball 10-15 gram of Stamen Nelumbinis 5-15 gram

Fructus Evodiae 6-10 gram of Herba Artemisiae Annuae 10-15 gram of Herba Artemisiae Scopariae 15-25 gram

Radix Et Rhizoma Rhei 10-20 gram of Rhizoma Coptidis 8-15 gram of Radix Glycyrrhizae 6-10 gram

Semen Arecae 10-15 gram of Fructus Aurantii 10-15 gram of Fructus Quisqualis 15-25 gram

Pivot stores 10-15 gram of Flos Rosae Laevigatae 5-10 gram Radix Scutellariae 8-15 gram

Ramulus Cinnamomi 6-10 gram of Rhizoma Corydalis 8-15 gram of Radix Angelicae Sinensis 8-10 gram

Pseudobulbus cremastrae seu pleiones 6-10 gram Rhizoma Osmundae 10-15 gram Herba Asari 5-10 gram

Cortex Phellodendri 8-15 gram of Rhizoma Zingiberis 5-8 gram of Rhizoma Atractylodis Macrocephalae 8-15 gram

Preferable amount is

Fructus Mume 12 grams of Pericarpium Zanthoxylies 6 grams of Cortex Magnoliae Officinalis 8 grams

Cortex Meliae 12 Cray ball 12 grams of Stamen Nelumbiniss 10 grams

Fructus Evodiae 8 grams of Herba Artemisiae Annuaes 12 grams of Herba Artemisiae Scopariae 20 grams

8 grams, Radix Et Rhizoma Rhei 15 grams of Rhizoma Coptidis 10 grams of Radix Glycyrrhizaes

Semen Arecae 12 grams of Fructus Aurantiis 12 grams of Fructus Quisqualis 20 grams

Pivot stores 12 grams of Flos Rosae Laevigataes, 8 grams of Radix Scutellariaes 12 grams

Ramulus Cinnamomi 8 grams of Rhizoma Corydalis 10 grams of Radix Angelicae Sinensis 10 grams

Pseudobulbus cremastrae seu pleiones 8 grams of Rhizoma Osmundae 12 grams of Herba Asaris 6 grams

Cortex Phellodendri 12 grams of Rhizoma Zingiberiss 6 grams of Rhizoma Atractylodis Macrocephalaes 10 grams

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Fructus Mume: pick clean impurity, sieve dedust bits, clean, dry;

2, Pericarpium Zanthoxyli: removing fruit stem and seed (Semen zanthoxyli), to put in pot stir-fry to making sound, oil goes out, take out, cool;

3, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;

4, Cortex Meliae: clean, slightly soak, run through, shredding, dry;

5, Omphalia: pick decontamination, clean and run through, section is dried;

6, Stamen Nelumbinis: get crude drug, removing impurity;

7, Fructus Evodiae: get crude drug, removing fruit stem, branch and impurity, sieve removes chip;

8, Herba Artemisiae Annuae: pick decontamination, removing undesirable root, water drenches and makes profit, cutting, dries;

9, Herba Artemisiae Scopariae: sieve, picks decontamination, and removing undesirable root, pulverizes, remove spare after square-bottomed bamboo basket;

10, Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity even, cuts into slices or is cut into small pieces, dries;

11, Rhizoma Coptidis: pick decontamination, cleans silt particle, runs through, and section, dries in the shade;

12, Radix Glycyrrhizae Preparata: extracting liquorice sheet adds cooked Mel and boiled water is a little, mixes thoroughly, slightly vexed, put in pot and fry to becoming buff with slow fire, till tack-free, taking-up cools, 100 jin, every Radix Glycyrrhizae, with refined honey 25-30 jin;

13, Semen Arecae: pick decontamination, soaks with clear water, changes water, to soaking, pick up by temperature situation, and section, dries;

14, Fructus Aurantii: removing flesh, core, cleans, slightly soaks, pull out, soften, and till pinching doubling with hands, section, dries;

15, Fructus Quisqualis: except decapsidate, gets clean core;

16, Herba Polygoni Avicularis: remove impurity and root, clean, soften, cutting is dried;

17, Flos Rosae Laevigatae: pick decontamination, dries;

18, Radix Scutellariae: pick decontamination, removes residual stem, infiltrates or put in boiled water slightly to soak to pull out with cold water, and run through rear section and dry, attention is avoided tanning by the sun excessively rubescent;

19, Ramulus Cinnamomi: slightly soak with water, pulls out, runs through, and section, dries, sieve anti-dandruff;

20, Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;

21, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;

22, Pseudobulbus cremastrae seu pleiones: eliminate fibrous root, cleans, and clear water soaks 2-4 hour, and taking-up runs through, and section, dries;

23, Rhizoma Osmundae: slightly soak with clear water, takes out, and each watering sooner or later once, softens, and section, dries;

24, Herba Asari: Ex-all impurity, by water spray profit, timely cutting, dries;

25, Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;

26, Rhizoma Zingiberis: pick clean impurity, be soaked in water 3-6 hour, pulls out, cuts into slices or dice, dry after moistening;

27, the Rhizoma Atractylodis Macrocephalae: pick clean impurity, be soaked in water, pull out after bubble, run through, section, dries.

Two, prepare

1, the Fructus Mume of described weight, Pericarpium Zanthoxyli, Cortex Magnoliae Officinalis, Cortex Meliae, Omphalia, Stamen Nelumbinis, Fructus Evodiae, Herba Artemisiae Annuae, Herba Artemisiae Scopariae, Radix Et Rhizoma Rhei, Rhizoma Coptidis, Radix Glycyrrhizae Preparata, Semen Arecae, Fructus Aurantii, Fructus Quisqualis, Herba Polygoni Avicularis, Flos Rosae Laevigatae, Radix Scutellariae, Ramulus Cinnamomi, Rhizoma Corydalis, Radix Angelicae Sinensis, Pseudobulbus cremastrae seu pleiones, Rhizoma Osmundae, Herba Asari, Cortex Phellodendri, Rhizoma Zingiberis, the Rhizoma Atractylodis Macrocephalae are decocted with water twice; add water 8 times amount for the first time; intense fire decocts boiling 10 minutes; use slow fire boiling again 25 minutes; filter first time decoction liquor, first time decoction liquor is poured in container.

2, add water the medicinal residues that first time filters 6 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor.

3, twice decoction liquor is merged, obtain medicinal liquid, be divided into by medicinal liquid 6 doses to take.

The present invention selects Fructus Mume to be monarch drug, and Omphalia, Rhizoma Coptidis are ministerial drug, and Pericarpium Zanthoxyli is adjuvant drug, and said medicine and all medicines, for making medicine, are combined the medicine made and treat ascariasis by Radix Glycyrrhizae.

Medicine of the present invention has convergence and promotes the production of body fluid, warming spleen and stomach for dispelling cold, heat-clearing and toxic substances removing, pain relieving, removing food stagnancy, effect of parasite killing, and treatment ascariasis instant effect, short treating period, do not recur.

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test report and the clinical observation material of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation material of [test example 2] medicine of the present invention

1, physical data

Accept outpatient service adult patient 38 example for medical treatment, more than 6 years old child 17 example.

2, diagnostic criteria

Because the parasitic site of polypide is different and different with the stage of development.

The ascarid larva of a tapeworm or the cercaria of a schistosome disease ascarid larva of a tapeworm or the cercaria of a schistosome of dividing a word with a hyphen at the end of a line causes heating, general malaise, urticaria etc. when pin main body internal migration.Cause the symptoms such as cough, asthma, sputum mixed with blood silk after arriving at lungs, severe one can have chest pain, dyspnea and cyanosis.Lung X-ray radiological survey X is migrating property wellability shade as seen, is called that hypersensitivity pneumonitis or Loew strangle Cotard clinically.Peripheral blood eosinophilic granulocyte showed increased, patient's apoplexy due to phlegm of about 10% can find the ascarid larva of a tapeworm or the cercaria of a schistosome.

Intestinal ascariasis common sympton has umbilicus week to fall into pain, inappetence, polyphagia, diarrhoea, constipation, urticaria etc., and child has sialorrhea, grinds one's teeth in sleep, dysphoria etc., and malnutrition appears in severe one.Change as high heat once parasitic environment, ascarid can be twisted together agglomerating in enteric cavity, blocks enteric cavity and forms ascaris intestinal obstruction, there is violent paroxysmal abdominal colic in patient, is very, with Nausea and vomiting with umbilical part, and the ascarid that can spue, abdominal part can touch mobile sausage sample and to swell thing.Sometimes ascaris intestinal obstruction can develop into strangulated intestinal obstruction, volvulus or intussusception.

Dystopy ascariasis ascarid has the habit of boring, can leave intestinal and enter other internal organs with holes, cause dystopy ascariasis when intestinal parasitic environment changes, common following several: 1. ascariasis of biliary tract, be many with child and person between twenty and fifty, women is more common.Inducement has high heat, diarrhoea, gestation, childbirth etc.During gestation, gastric acid reduces, and the uterus of expanding forces intestinal to be shifted, and uterine contraction strong during childbirth brings out enterokinesia to be increased, and ascarid all can be impelled to drive in the wrong direction to bile duct.This sick morbidity suddenly, upper right abdomen partially in have violent paroxysmal colic, the sense of Drilling sample, patient is toss about and feel uneasy, Nausea and vomiting, and can spue ascarid.Interictal is without pain or only feel mild pain.If ascarid pierces liver can cause ascaris liver abscess, must operative treatment early.2. ductus pancreaticus ascariasis, how concurrent in ascariasis of biliary tract, clinical sign is like acute pancreatitis.3. appendix ascaris disease, is more common in child, because the bore of children's's appendix root is wider, easily for ascarid pierces.

3, Therapeutic Method

Select above-mentioned medicament, take to patient, be grown up each serving with 1 dose, each four/potion of child, every day is early, middle and late respectively takes 1 time, takes 3 days continuously.

4, efficacy assessment standard

Effective: ascariasis symptom is eliminated, recovery from illness, without recurring after observing half a year;

Take a turn for the better: ascariasis symptom is clearly better, appetite strengthens, and colic symptoms alleviates, progressively without stomachache;

Invalid: symptom, without improvement, does not reach improvement standard person.

5, therapeutic outcome

In above-mentioned treatment, by Drug therapy adult ascariasis patient 38 example of the present invention, effective 35 examples of result, obvious effective rate is 92.11%, and take a turn for the better 2 examples, and improvement rate is 5.26%, and invalid 1 example, total effective rate is 97.37%.Treatment child ascariasis patient 17 example, effective 15 examples of result, obvious effective rate is 88.24%, and take a turn for the better 2 examples, and improvement rate is 11.76%, and total effective rate is 100%.

Claims

1. treat a medicine for ascariasis, it is characterized in that, it is made up of the crude drug in following weight range:

Cortex Meliae 10-15 Cray ball 10-15 gram of Stamen Nelumbinis 5-15 gram

Cortex Phellodendri 8-15 gram of Rhizoma Zingiberis 5-8 gram of Rhizoma Atractylodis Macrocephalae 8-15 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Cortex Meliae 12 Cray ball 12 grams of Stamen Nelumbiniss 10 grams

Cortex Phellodendri 12 grams of Rhizoma Zingiberiss 6 grams of Rhizoma Atractylodis Macrocephalaes 10 grams.

3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:

(1) get the raw materials ready

(1) Fructus Mume: pick clean impurity, sieve dedust bits, clean, dry;

(2) Pericarpium Zanthoxyli: removing fruit stem and seed (Semen zanthoxyli), to put in pot stir-fry to making sound, oil goes out, take out, cool;

(3) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;

(4) Cortex Meliae: clean, slightly soak, run through, shredding, dry;

(5) Omphalia: pick decontamination, clean and run through, section is dried;

(6) Stamen Nelumbinis: get crude drug, removing impurity;

(7) Fructus Evodiae: get crude drug, removing fruit stem, branch and impurity, sieve removes chip;

(8) Herba Artemisiae Annuae: pick decontamination, removing undesirable root, water drenches and makes profit, cutting, dries;

(9) Herba Artemisiae Scopariae: sieve, picks decontamination, and removing undesirable root, pulverizes, remove spare after square-bottomed bamboo basket;

(10) Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity even, cuts into slices or is cut into small pieces, dries;

(11) Rhizoma Coptidis: pick decontamination, cleans silt particle, runs through, and section, dries in the shade;

(12) Radix Glycyrrhizae Preparata: extracting liquorice sheet adds cooked Mel and boiled water is a little, mixes thoroughly, slightly vexed, put in pot and fry to becoming buff with slow fire, till tack-free, taking-up cools, 100 jin, every Radix Glycyrrhizae, with refined honey 25-30 jin;

(13) Semen Arecae: pick decontamination, soaks with clear water, changes water, to soaking, pick up by temperature situation, and section, dries;

(14) Fructus Aurantii: removing flesh, core, cleans, slightly soaks, pull out, soften, and till pinching doubling with hands, section, dries;

(15) Fructus Quisqualis: except decapsidate, gets clean core;

(16) Herba Polygoni Avicularis: remove impurity and root, clean, soften, cutting is dried;

(17) Flos Rosae Laevigatae: pick decontamination, dries;

(18) Radix Scutellariae: pick decontamination, removes residual stem, infiltrates or put in boiled water slightly to soak to pull out with cold water, and run through rear section and dry, attention is avoided tanning by the sun excessively rubescent;

(19) Ramulus Cinnamomi: slightly soak with water, pulls out, runs through, and section, dries, sieve anti-dandruff;

(20) Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;

(21) Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;

(22) Pseudobulbus cremastrae seu pleiones: eliminate fibrous root, cleans, and clear water soaks 2-4 hour, and taking-up runs through, and section, dries;

(23) Rhizoma Osmundae: slightly soak with clear water, takes out, and each watering sooner or later once, softens, and section, dries;

(24) Herba Asari: Ex-all impurity, by water spray profit, timely cutting, dries;

(25) Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;

(26) Rhizoma Zingiberis: pick clean impurity, be soaked in water 3-6 hour, pulls out, cuts into slices or dice, dry after moistening;

(27) Rhizoma Atractylodis Macrocephalae: pick clean impurity, be soaked in water, pull out after bubble, run through, section, dries;

(2) prepare

(1) Fructus Mume of described weight, Pericarpium Zanthoxyli, Cortex Magnoliae Officinalis, Cortex Meliae, Omphalia, Stamen Nelumbinis, Fructus Evodiae, Herba Artemisiae Annuae, Herba Artemisiae Scopariae, Radix Et Rhizoma Rhei, Rhizoma Coptidis, Radix Glycyrrhizae Preparata, Semen Arecae, Fructus Aurantii, Fructus Quisqualis, Herba Polygoni Avicularis, Flos Rosae Laevigatae, Radix Scutellariae, Ramulus Cinnamomi, Rhizoma Corydalis, Radix Angelicae Sinensis, Pseudobulbus cremastrae seu pleiones, Rhizoma Osmundae, Herba Asari, Cortex Phellodendri, Rhizoma Zingiberis, the Rhizoma Atractylodis Macrocephalae are decocted with water twice, add water 8 times amount for the first time, intense fire decocts boiling 10 minutes, use slow fire boiling again 25 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;

(2) add water the medicinal residues that first time filters 6 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;

(3) twice decoction liquor is merged and get final product.