CN103638501A - Medicament for treating biliary ascariasis and preparation method of medicament - Google Patents
Medicament for treating biliary ascariasis and preparation method of medicament Download PDFInfo
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Abstract
The invention discloses a medicament for treating biliary ascariasis and a preparation method of the medicament. The medicament is mainly prepared from medicines such as areca-nut, mangnolia officinalis, quispualis indica, pepper, pericarpium arecae, endothelium corneum gigeriae galli, codonopsis pilosula, lysimachia christinae hance, jujube and the like according to a certain weight ratio. The medicament disclosed by the invention has the functions of warming the spleen and stomach for dispelling cold, dehumidifying, expelling parasite, removing food retention and tonifying the spleen, and is rapid to take an effect and good in curative effect when used for treating biliary ascariasis, and the disease does not reoccur after being healed.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of ascariasis of biliary tract and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Ascariasis of biliary tract is a kind of complication the most serious in intestinal ascariasis.Be more common in 6-8 school age population in year, peasant and late period anemia of pregnant woman.It is that the bellyworm motion being caused by a variety of causes is active, and pierces biliary tract and the acute upper abdominal pain or the biliary tract infection that occur.During outbreak, Principle of Pain endurable, wails and cries, very painful.If treatment measure does not catch up with, can there is dehydration and acidosis in various degree, even threat to life in end-stage patients.At present, western medicine ascariasis of biliary tract poor effect, and long-term taking Western medicine has more side effect, and therefore, there is very large demand to the Chinese medicine of effective treatment ascariasis of biliary tract in people.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment ascariasis of biliary tract, thereby has completed the present invention.
Object of the present invention is just to provide a kind of composition of medicine that can effectively treat ascariasis of biliary tract.
Another object of the present invention has just been to provide the preparation method of this composition of medicine.
Medicine of the present invention selects Semen Arecae, Cortex Magnoliae Officinalis, Fructus Quisqualis, Pericarpium Zanthoxyli, Pericarpium Arecae, Endothelium Corneum Gigeriae Galli, Radix Codonopsis, Herba Lysimachiae, Fructus Jujubae, Rhizoma Zingiberis, Radix Et Rhizoma Rhei, Herba Taraxaci, Herba Pogostemonis, Rhizoma Osmundae, Concha Ostreae, Herba Asari, Folium Sennae, Cortex Meliae, the Rhizoma Pinelliae, Fructus Mume, Alumen, Semen Torreyae medicine to combine, make each efficacy of drugs produce synergism these drug regimens, thus recurrence that can fast treating ascariasis of biliary tract.Wherein selecting Semen Arecae is that temperature, enters spleen, stomach, large intestine channel, has parasite killing because of its nature and flavor toil, removing mass, and the therapeutic method to keep the adverse QI flowing downwards, the function of row water, controls malnutrition due to parasitic infestation, dyspepsia, and abdominal distention is heavy after dysentery, malaria, edema, beriberi, accumulation of phlegm in the hypochondrium ， Disorder knot.Selecting Cortex Magnoliae Officinalis is that temperature, enters spleen, stomach, large intestine channel, has warming middle-JIAO because of its nature and flavor toil, the therapeutic method to keep the adverse QI flowing downwards, and dampness, the function of expectorant, controls breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, cold-damp dysentery.Select Fructus Quisqualis to be because its nature and flavor are sweet, temperature, poisonous, enter spleen, stomach warp, there is parasite killing, removing food stagnancy, the function of spleen invigorating, controls ascarid stomachache, infantile malnutrition, breast food is stagnated, abdominal distention, dysentery.Select Pericarpium Zanthoxyli to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, lung, kidney channel, there is warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, separate fish raw meat poison, control food stagnation and stop drink, trusted subordinate's cold type of pain, vomiting, oh, and cough with dyspnea, anemofrigid-damp arthralgia, has loose bowels, dysentery, colic, toothache, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies.Select Pericarpium Arecae to be because its nature and flavor are pungent, tepor, enters spleen, stomach, intestine and small intestine warp, has therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, and the function of row water is controlled gastral cavity abdomen painful abdominal mass swollen, beriberi, edema.Select Endothelium Corneum Gigeriae Galli to be because its nature and flavor are sweet, flat, enter spleen, stomach warp, there is removing food stagnancy stagnant, the function of strengthening the spleen and stomach, controls food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, and fatigue and lack of strength, lack of appetite, thirsty, chronic diarrhea, proctoptosis.Select Herba Lysimachiae to be because its nature and flavor toil is cool, have heat clearing away, diuresis, antitussive, detumescence, the function of removing toxic substances, the subcutaneous ulcer of harnessing the Yellow River, edema, vesical calculus, malaria, lung abscess, cough, spits blood, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, infantile malnutrition ， Jing Epilepsy, carbuncle, skin ulcer tinea, eczema.Select Fructus Jujubae to be because its nature and flavor are sweet, temperature, enters spleen, stomach warp, has spleen reinforcing stomach function regulating, and supplementing QI for promoting the production of body fluid adjusts battalion to defend, and separates the function of poison of drug, controls insufficiency of stomach lack of appetite, the weak loose stool of spleen, and qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Select Rhizoma Zingiberis to be because its nature and flavor are pungent, heat, enters spleen, stomach, lung meridian, has warming middle-JIAO by cold, and the function that recuperating depleted YANG is promoted blood circulation, controls trusted subordinate's cold type of pain, vomit and diarrhoea, and cold extremities faint pulse, cold fluid-retention is breathed with cough, anemofrigid-damp arthralgia, yang deficiency is told, nosebleed, hematochezia.Select Radix Et Rhizoma Rhei to be because its nature and flavor are bitter, cold, enter stomach, large intestine, liver footpath, have the poison of purging heat, removing mass is stagnant, the function of clots absorbing blood, controls excess-heat constipation, and delirium is gone mad, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinates red, carbuncle and ulcer toxic swelling, furuncle, burn.Select Herba Taraxaci to be because its property bitter but sweet flavor is cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Select Herba Pogostemonis be because its nature and flavor pungent, tepor, enters lung, spleen, stomach warp, has fast gas, and in, ward off dirty, the function of damp eliminating, the heat-damp in summer that cures cold, cold and heat, headache, breast gastral cavity painful abdominal mass is vexed, vomiting is had loose bowels, malaria, dysentery, halitosis.Select Rhizoma Osmundae to be because its nature and flavor are bitter, cool, enter liver, stomach warp, kill ascarid, silk ribbon, pinworm, heat clearing away, removing toxic substances, removing heat from blood, the function of hemostasis, controls anemopyretic cold, and damp and hot skin eruption is spitted blood, epistaxis, discharging fresh blood stool, dysentery, metrorrhagia, leukorrhagia.Select Concha Ostreae to be because its nature and flavor are salty and bitter, cool, enter liver, kidney channel, have yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduces phlegm, the function of softening the hard mass, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Select Herba Asari to be because its nature and flavor are pungent, temperature, enters lung, kidney channel, dispel the wind, and cold expelling, row water, opens the function of stealing, and controls air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Select Folium Sennae to be because its nature and flavor sweetness and bitterness is cold, enter large intestine channel, have the function of the intestinal stasis relieving that purges heat, control constipation with heat retention, stagnant abdominal distention.Select Cortex Meliae to be because its nature and flavor are bitter, cold, poisonous, there is heat clearing away, dampness, the function of parasite killing, controls ascarid, pinworm, rubella, scabies.Select the Rhizoma Pinelliae to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, stomach warp, there is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass, controls damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness, outer subduing inflammation.Select Fructus Mume to be because its nature and flavor are sour, temperature, enters liver, spleen, and lung, large intestine channel, has convergence to promote the production of body fluid, and the function of relieving colic caused by ascaris anthelmintic, controls chronic cough, deficiency-heat excessive thirst, chronic malaria, dysentery, has blood in stool, hematuria, metrorrhagia, ascariasis of biliary tract stomachache, vomiting, ancylostomiasis, psoriasis, bulbar conjunctiva polyp.Select Alumen to be because its nature and flavor are sour and astringent, cold, poisonous, enter lung, spleen, stomach, large intestine channel, there is expectorant, dampness, antidiarrheal, removing toxic substances, the function of parasite killing, Zhi epilepsy, sore throat, sputum is stopped up very, hepatitis, jaundice, general edema with yellowish skin, Stomach duodenum ulcer, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, water, fire, insect bite.Select Semen Torreyae to be because its nature and flavor are sweet, flat, enter lung, stomach, large intestine channel, there is parasite killing, removing food stagnancy, the function of moisturizing, controls abdominal pain due to worm stagnation, infantile malnutrition, cough caused by dryness, constipation, hemorrhoid.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Semen Arecae 15-25 gram of Cortex Magnoliae Officinalis 10-20 gram of Fructus Quisqualis 15-25 gram
Pericarpium Zanthoxyli 5-15 gram of Pericarpium Arecae 10-20 gram of Endothelium Corneum Gigeriae Galli 10-20 gram
Radix Codonopsis 15-25 gram of Herba Lysimachiae 5-15 gram of Fructus Jujubae 15-25 gram
Rhizoma Zingiberis 15-25 gram of Radix Et Rhizoma Rhei 10-20 gram of Herba Taraxaci 15-25 gram
Herba Pogostemonis 5-15 gram of Rhizoma Osmundae 5-15 gram of Concha Ostreae 15-25 gram
Herba Asari 15-25 gram of Folium Sennae 10-20 gram of Cortex Meliae 3-9 gram
Rhizoma Pinelliae 5-15 gram of Fructus Mume 5-15 gram of Alumen 15-25 gram
Semen Torreyae 25-35 gram
Preferable amount is
20 grams of 15 grams of Fructus Quisqualis of 20 grams of Cortex Magnoliae Officinalis of Semen Arecae
15 grams of 15 grams of Endothelium Corneum Gigeriae Galli of 10 grams of Pericarpium Arecae of Pericarpium Zanthoxyli
20 grams, 10 grams of Fructus Jujubaes of 20 grams of Herba Lysimachiaes of Radix Codonopsis
20 grams of 15 grams of Herba Taraxacis of 20 grams of Radix Et Rhizoma Rhei of Rhizoma Zingiberis
20 grams of 10 grams of Concha Ostreaes of 10 grams of Rhizoma Osmundae of Herba Pogostemonis
6 grams of 15 grams of Cortex Meliaees of 20 grams of Folium Sennae of Herba Asari
20 grams of 10 grams of Alumens of 10 grams of Fructus Mumes of the Rhizoma Pinelliae
30 grams of Semen Torreyaes
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Semen Arecae: choose decontamination, soak with clear water, change water by temperature situation, till soaking, pick up, section, dries;
2, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding, dries;
3, Semen Quisqualis: except decapsidate, get clean core;
4, Pericarpium Zanthoxyli: remove fruit stem and seed Semen zanthoxyli, put pot interior stir-fry to making sound, oil goes out, and takes out, cool;
5, Pericarpium Arecae: choose clean impurity, rolloff makes soft, beats, and sieve removes spare;
6, Endothelium Corneum Gigeriae Galli: choose decontamination, rinse and dry;
7, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
8, Herba Lysimachiae: choose clean impurity, sieve dedust bits, dry;
9, Fructus Jujubae: choose clean impurity, dry;
10, Rhizoma Zingiberis: choose clean impurity, the 3-6 hour that is soaked in water, pulls out, cuts into slices after moistening or dices, and dries;
11, Radix et Rhizoma Rhei (stir-fried with wine): get rhubarb tablets and evenly spray with yellow wine, micro-stewing, to put in pot and use the micro-stir-fry of slow fire, taking-up is dried, and 100 jin of rhubarb tablets, with 14 jin of yellow wine;
12, Herba Taraxaci: choose decontamination, clean earth, cutting, dries;
13, Herba Pogostemonis: choose decontamination, remove undesirable root and old stem, first leaf is taken separately and put, stem water runs through, and cutting is dried, then with leaf and even;
14, Rhizoma Osmundae: slightly soak with clear water, take out, each watering sooner or later once, softens, and section, dries;
15, Concha Ostreae: clean, dry, pulverize use;
16, Herba Asari: Ex-all impurity, water spray profit, cutting in time, dries;
17, Folium Sennae: get crude drug, except discarding stalk, impurity;
18, Cortex Meliae: clean, slightly soak, run through, shredding, dries;
19, the Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
20, Fructus Mume: choose clean impurity, sieve dedust bits, clean, and dry;
21, Alumen: choose clean impurity, the used time smashs to pieces;
22, Semen Torreyae: choose clean impurity, or shell and get core, the used time smashs to pieces.
Two, preparation
1, the Semen Arecae of described weight, Cortex Magnoliae Officinalis, Fructus Quisqualis, Pericarpium Zanthoxyli, Pericarpium Arecae, Endothelium Corneum Gigeriae Galli, Radix Codonopsis, Herba Lysimachiae, Fructus Jujubae, Rhizoma Zingiberis, Radix Et Rhizoma Rhei, Herba Taraxaci, Herba Pogostemonis, Rhizoma Osmundae, Concha Ostreae, Herba Asari, Folium Sennae, Cortex Meliae, the Rhizoma Pinelliae, Fructus Mume, Alumen, Semen Torreyae medicine are decocted with water to secondary, add for the first time 8 times of amounts of water, soak after 200 minutes, intense fire decocts boiling 10 minutes, use again slow fire boiling 35 minutes, filter to obtain decoction liquor for the first time.
2, the medicinal residues of filtration are added to 6 times of amounts of water, first boil with high heat, then use slow fire boiling 20 minutes, filter to obtain decoction liquor for the second time.
3, merge twice decoction liquor, be divided into 6 doses and take.
Medicine of the present invention has warming spleen and stomach for dispelling cold, dehumidifying, and parasite killing, removing food stagnancy, the function of spleen invigorating, is used for the treatment of ascariasis of biliary tract, short treating period, instant effect, has no side effect.
By test example, further set forth below the beneficial effect of medicine of the present invention, these test examples have comprised animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.5kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 30ml/kg, and normal amount is 15ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The observations of [test example 2] Drug therapy ascariasis of biliary tract of the present invention
1, physical data
Accept ascariasis of biliary tract patient totally 178 examples for medical treatment.
2, diagnostic criteria
(1) symptom
1. stomachache is normal for boring the violent angor of top sample under the xiphoid-process breaking out, patient's pale complexion, feel restless, dripping sweat, bend over to split with laughter, cry and shout incessantly, very painful, during abdominal colic, can take on back to the right to diffuse, but also can alleviate suddenly.Stomachache mostly is paroxysmal, intermittently outbreak, and the persistent period is different in size, after pain, can or tease as ordinary person's peace and quiet, or lethargy.This symptom is the feature of biliary ascariasis, helps diagnosis.Angor often in an endless stream enters due to biliary tract in sphincter place or most adult because of polypide incarceration, and even angor shows effect, is difficult to alleviate again and again.When sphincter is tired, lax, ascarid all enters biliary tract or exits biliary tract, temporary transient when static, symptom can respite.While there is biliary tract infection, stomachache continues.When merging liver abscess, can there be hepatic region, lower back distending pain.While merging acute pancreatitis, stomachache can expand to upper abdomen middle part, upper left abdomen and lower back.If ascarid causes biliary tract perforation, can occur that full abdomen continues tormina and peritoneal irritation sign.When ascarid causes hemobilia, can there be the explosive pain of upper abdomen, slight jaundice and massive bleeding from upper digestive tract three to levy.When biliary tract infection is serious, can there is septicemia etc.[cuisines China]
2. nausea and vomiting often has generation, how, when angor, occurs together, in spew, can contain bile or xanthochromia ascarid.What have is " retch ", and patient can not normally take food.
3. General Symptoms is early stage without the heating of obviously feeling cold, and can have feel cold heating and jaundice when complicated with acute pyogenic cholangitis, cholecystitis.As concurrent liver abscess, subphrenic infection, septicemia etc., there is the high heat of shiver with cold, even toxic shock etc.
(2) although the early stage upper angina abdominis of sign, abdomen is soft or only upper abdomen is deeply in slight tenderness, without muscle tonus, significantly different from other acute abdomen.As there is liver, gallbladder pyogenic infection, peritonitis, can have peritoneal irritation sign: abdominal tenderness, rebound tenderness and muscle tonus late period.Maybe can touch enlargement and have liver, gallbladder of tenderness etc.Due to biliary tract ascarid obstruction or cholelithiasis and deposit, or liver toxic lesion, jaundice in various degree can be had.
3, Therapeutic Method
Select above-mentioned medicament, to patient, take, each serving with 1 dose, every day early, respectively take 1 evening, within 5 days, is a course for the treatment of, takes continuously 4 courses for the treatment of.
4, efficacy assessment standard
Effective: ascariasis of biliary tract transference cure, observe half a year without bounce-back person;
Take a turn for the better: ascariasis of biliary tract symptom is obviously improved, and body constitution progressively strengthens;
Invalid: ascariasis of biliary tract symptom, without change, does not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy ascariasis of biliary tract patient of the present invention 178 examples, effective 169 examples of result, obvious effective rate is 94.94%, 6 examples that take a turn for the better, and improvement rate is 3.37%, invalid 3 examples, total effective rate is 98.31%.
Claims (3)
1. a medicine for the treatment of ascariasis of biliary tract, is characterized in that: it is to be made by the crude drug in following weight range:
Semen Arecae 15-25 gram of Cortex Magnoliae Officinalis 10-20 gram of Fructus Quisqualis 15-25 gram
Pericarpium Zanthoxyli 5-15 gram of Pericarpium Arecae 10-20 gram of Endothelium Corneum Gigeriae Galli 10-20 gram
Radix Codonopsis 15-25 gram of Herba Lysimachiae 5-15 gram of Fructus Jujubae 15-25 gram
Rhizoma Zingiberis 15-25 gram of Radix Et Rhizoma Rhei 10-20 gram of Herba Taraxaci 15-25 gram
Herba Pogostemonis 5-15 gram of Rhizoma Osmundae 5-15 gram of Concha Ostreae 15-25 gram
Herba Asari 15-25 gram of Folium Sennae 10-20 gram of Cortex Meliae 3-9 gram
Rhizoma Pinelliae 5-15 gram of Fructus Mume 5-15 gram of Alumen 15-25 gram
Semen Torreyae 25-35 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
20 grams of 15 grams of Fructus Quisqualis of 20 grams of Cortex Magnoliae Officinalis of Semen Arecae
15 grams of 15 grams of Endothelium Corneum Gigeriae Galli of 10 grams of Pericarpium Arecae of Pericarpium Zanthoxyli
20 grams, 10 grams of Fructus Jujubaes of 20 grams of Herba Lysimachiaes of Radix Codonopsis
20 grams of 15 grams of Herba Taraxacis of 20 grams of Radix Et Rhizoma Rhei of Rhizoma Zingiberis
20 grams of 10 grams of Concha Ostreaes of 10 grams of Rhizoma Osmundae of Herba Pogostemonis
6 grams of 15 grams of Cortex Meliaees of 20 grams of Folium Sennae of Herba Asari
20 grams of 10 grams of Alumens of 10 grams of Fructus Mumes of the Rhizoma Pinelliae
30 grams of Semen Torreyaes.
3. according to the preparation method of medicine described in claim 1 or 2, it is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Semen Arecae: choose decontamination, soak with clear water, change water by temperature situation, till soaking, pick up, section, dries;
(2) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding, dries;
(3) Semen Quisqualis: except decapsidate, get clean core;
(4) Pericarpium Zanthoxyli: remove fruit stem and seed Semen zanthoxyli, put pot interior stir-fry to making sound, oil goes out, and takes out, cool;
(5) Pericarpium Arecae: choose clean impurity, rolloff makes soft, beats, and sieve removes spare;
(6) Endothelium Corneum Gigeriae Galli: choose decontamination, rinse and dry;
(7) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
(8) Herba Lysimachiae: choose clean impurity, sieve dedust bits, dry;
(9) Fructus Jujubae: choose clean impurity, dry;
(10) Rhizoma Zingiberis: choose clean impurity, the 3-6 hour that is soaked in water, pulls out, cuts into slices after moistening or dices, and dries;
(11) Radix et Rhizoma Rhei (stir-fried with wine): get rhubarb tablets and evenly spray with yellow wine, micro-stewing, to put in pot and use the micro-stir-fry of slow fire, taking-up is dried, and 100 jin of rhubarb tablets, with 14 jin of yellow wine;
(12) Herba Taraxaci: choose decontamination, clean earth, cutting, dries;
(13) Herba Pogostemonis: choose decontamination, remove undesirable root and old stem, first leaf is taken separately and put, stem water runs through, and cutting is dried, then with leaf and even;
(14) Rhizoma Osmundae: slightly soak with clear water, take out, each watering sooner or later once, softens, and section, dries;
(15) Concha Ostreae: clean, dry, pulverize use;
(16) Herba Asari: Ex-all impurity, water spray profit, cutting in time, dries;
(17) Folium Sennae: get crude drug, except discarding stalk, impurity;
(18) Cortex Meliae: clean, slightly soak, run through, shredding, dries;
(19) Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
(20) Fructus Mume: choose clean impurity, sieve dedust bits, clean, and dry;
(21) Alumen: choose clean impurity, the used time smashs to pieces;
(22) Semen Torreyae: choose clean impurity, or shell and get core, the used time smashs to pieces;
(2) preparation
(1) Semen Arecae of described weight, Cortex Magnoliae Officinalis, Fructus Quisqualis, Pericarpium Zanthoxyli, Pericarpium Arecae, Endothelium Corneum Gigeriae Galli, Radix Codonopsis, Herba Lysimachiae, Fructus Jujubae, Rhizoma Zingiberis, Radix Et Rhizoma Rhei, Herba Taraxaci, Herba Pogostemonis, Rhizoma Osmundae, Concha Ostreae, Herba Asari, Folium Sennae, Cortex Meliae, the Rhizoma Pinelliae, Fructus Mume, Alumen, Semen Torreyae medicine are decocted with water to secondary, add for the first time 8 times of amounts of water, soak after 200 minutes, intense fire decocts boiling 10 minutes, use again slow fire boiling 35 minutes, filter to obtain decoction liquor for the first time;
(2) medicinal residues of filtration are added to 6 times of amounts of water, first boil with high heat, then use slow fire boiling 20 minutes, filter to obtain decoction liquor for the second time;
(3) merge twice decoction liquor, be divided into 6 doses and take.
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