CN102786433A - 一种延胡索酰胺类化合物提取物及其制备方法和应用 - Google Patents
一种延胡索酰胺类化合物提取物及其制备方法和应用 Download PDFInfo
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- CN102786433A CN102786433A CN2012100685813A CN201210068581A CN102786433A CN 102786433 A CN102786433 A CN 102786433A CN 2012100685813 A CN2012100685813 A CN 2012100685813A CN 201210068581 A CN201210068581 A CN 201210068581A CN 102786433 A CN102786433 A CN 102786433A
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- fumaryl
- extract
- aminated compounds
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- extraction
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- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 claims description 12
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- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
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- JUGOREOARAHOCO-UHFFFAOYSA-M acetylcholine chloride Chemical compound [Cl-].CC(=O)OCC[N+](C)(C)C JUGOREOARAHOCO-UHFFFAOYSA-M 0.000 description 2
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Images
Abstract
Description
树脂 | HPD100 | X-5 | DA201 | D301 | AB-8 |
得率 | 0.11% | 0.07% | 0.16% | 0.08% | 0.15 |
含量 | 80% | 65% | 56% | 58% | 76% |
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CN201210068581.3A CN102786433B (zh) | 2012-03-15 | 2012-03-15 | 一种延胡索酰胺类化合物提取物及其制备方法和应用 |
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CN201210068581.3A CN102786433B (zh) | 2012-03-15 | 2012-03-15 | 一种延胡索酰胺类化合物提取物及其制备方法和应用 |
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CN102786433A true CN102786433A (zh) | 2012-11-21 |
CN102786433B CN102786433B (zh) | 2016-09-21 |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050123539A1 (en) * | 2003-08-04 | 2005-06-09 | James Rusnak | Methods for treating cardiovascular disease using a soluble CTLA4 molecule |
WO2007115657A2 (de) * | 2006-04-07 | 2007-10-18 | Henkel Ag & Co. Kgaa | Aufhell- und/oder färbemittel mit guter hautverträglichkeit |
CN101062106A (zh) * | 2006-04-25 | 2007-10-31 | 长春英联生物技术有限公司 | 延胡索提取物分散片及其制备方法 |
US20070299131A1 (en) * | 2003-12-27 | 2007-12-27 | Korea Research Institute Of Chemical Technology | Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them |
CN101284050A (zh) * | 2008-05-09 | 2008-10-15 | 浙江康恩贝制药股份有限公司 | 延胡索水溶性部位药物及制备方法和用途 |
CN101406527A (zh) * | 2008-11-27 | 2009-04-15 | 黑龙江中医药大学 | 延胡索总生物碱盐的制备方法及其作为治疗心血管疾病药物的应用 |
-
2012
- 2012-03-15 CN CN201210068581.3A patent/CN102786433B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050123539A1 (en) * | 2003-08-04 | 2005-06-09 | James Rusnak | Methods for treating cardiovascular disease using a soluble CTLA4 molecule |
US20070299131A1 (en) * | 2003-12-27 | 2007-12-27 | Korea Research Institute Of Chemical Technology | Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them |
WO2007115657A2 (de) * | 2006-04-07 | 2007-10-18 | Henkel Ag & Co. Kgaa | Aufhell- und/oder färbemittel mit guter hautverträglichkeit |
CN101062106A (zh) * | 2006-04-25 | 2007-10-31 | 长春英联生物技术有限公司 | 延胡索提取物分散片及其制备方法 |
CN101284050A (zh) * | 2008-05-09 | 2008-10-15 | 浙江康恩贝制药股份有限公司 | 延胡索水溶性部位药物及制备方法和用途 |
CN101406527A (zh) * | 2008-11-27 | 2009-04-15 | 黑龙江中医药大学 | 延胡索总生物碱盐的制备方法及其作为治疗心血管疾病药物的应用 |
Non-Patent Citations (2)
Title |
---|
D.SUBHAS BOSE,P.RAVINDER GOUD: "Aryl chlorothionoformate: A new versatile reagent for the preparation of Nitriles and Isonitriles under mild conditions", 《TETRAHEDRON LETTERS》 * |
IAN BIRD,PETER B.FARMER: "The synthesis of deuterium-labeled 2-bromoethanol, acrylonitrile, acrylamide, 2-aminoethanol, 2-bromoethylamine hydrobromide and 1-bromo-2-chloroethane", 《JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS》 * |
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Denomination of invention: A fumaramide compound extract and its preparation method and application Effective date of registration: 20221024 Granted publication date: 20160921 Pledgee: Bank of China Limited Lanxi Sub-branch Pledgor: ZHEJIANG CONBA PHARMACEUTICAL Co.,Ltd. Registration number: Y2022980019363 |
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Granted publication date: 20160921 Pledgee: Bank of China Limited Lanxi Sub-branch Pledgor: ZHEJIANG CONBA PHARMACEUTICAL Co.,Ltd. Registration number: Y2022980019363 |
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