CN102764334A - Medicinal composition for treating hyperlipidemia - Google Patents
Medicinal composition for treating hyperlipidemia Download PDFInfo
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- CN102764334A CN102764334A CN2012102477849A CN201210247784A CN102764334A CN 102764334 A CN102764334 A CN 102764334A CN 2012102477849 A CN2012102477849 A CN 2012102477849A CN 201210247784 A CN201210247784 A CN 201210247784A CN 102764334 A CN102764334 A CN 102764334A
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Abstract
The invention discloses a medicinal composition for treating hyperlipidemia. The medicinal composition is prepared from seven Chinese medicines, namely gynostemma pentaphylla, fructus crataegi, wild chrysanthemum, root of red-rooted salvia, cortex eucommiae, crude rehmannia root and dock root; the medicinal composition has the effects of invigorating the circulation of blood and dissipating blood stasis, tonifying qi and relieving pain, relieving asthma and reducing blood pressure, and has a good curative effect on high blood fat, thick blood fat, cerebrovascular diseases, atherosclerosis, peripheral arteriosclerotic disease and the like; and the invention provides a good choice for medicaments for treating hyperlipidemia.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition of treating hyperlipemia, belong to technical field of Chinese medicine.
Background technology
Fat metabolism or running make one or more lipids of blood plasma be higher than normally to be called hyperlipidemia unusually.Hyperlipidemia is a kind of systemic disease, refers to that T-CHOL in the blood (TC) and/or triglyceride (TG) are too high or HDL-C (HDL-C) is low excessively, and modern medicine is referred to as dyslipidemia.Lipid is insoluble or be slightly soluble in water, must exist with the lipoprotein form with protein bound, and therefore, hyperlipidemia is also referred to as hyperlipoproteinemia usually.A large amount of research datas show that hyperlipidemia is apoplexy, coronary heart disease, myocardial infarction, cardiac sudden death is independent and important risk.Therefore, particularly important to the prevention and the treatment of this disease.The symptom of general hyperlipidemia shows as more: dizziness, spiritlessness and weakness, insomnia forgetfulness, numb limbs and tense tendons, uncomfortable in chest, cardiopalmus etc.; Can occur when heavier having a dizzy spell, headache, uncomfortable in chest, breathe hard, have palpitation, symptom such as chest pain, weak, distortion of commissure, mute, numb limbs and tense tendons; Finally can cause serious diseases such as coronary heart disease, apoplexy, and corresponding performance occur.Long-term blood fat is high, and lipid deposits caused atherosclerosis at blood vessel endothelium, can cause coronary heart disease and peripheral arterial disease etc., shows as angina pectoris, myocardial infarction, apoplexy and intermittent claudication (pain behind the limb activity).
Diseases such as general treatment hyperlipidemia and hypertension adopt Western medicine, but because this sick particularity often can not reach the effect of eradicating fully in a short time, and Western medicine is taken for a long time and had many toxic and side effects.Chinese medicine three-hypers disease has the history in thousands of years, has put down in writing the Chinese medicine and the prescription of a large amount of treatment hyperlipidemia in the successive dynasties medical book, has accumulated rich experience.Discover in a large number that in recent years some Chinese medicine and effective ingredient thereof have the effect of tangible triglyceride reducing,, have significant prevention and therapeutical effect, obtained some gratifying achievements for the incidence and development of hyperlipemia.
The inventor is based on drug world working experience for many years; On the basis of using for reference the good drug effect of Western medicine, according to Chinese medicine theoretical with dialectical method, through to many-sided carefully conscientious researchs such as the property of medicine of medical material, drug effects; Try hard to from Chinese herbal medicine, find out the treatment hyperlipemia; Especially the caused blood fat of hyperlipemia is high, blood fat is dense, atherosclerosis, cerebrovascular, and instant effect, component are simple, the good widely pharmaceutical formulation of clinical practice; Through experiment and exploration many times, successfully develop the present invention finally.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition of treating hyperlipemia, another purpose provides the method for preparing of this pharmaceutical composition and preparation thereof.
Another purpose of the present invention provides the purposes of said medicine in the following disease of treatment.This medicine is mainly used in the treatment hyperlipemia, and especially high, the symptoms such as blood fat is dense, atherosclerosis, cerebrovascular of the caused blood fat of hyperlipemia have curative effect preferably, and good effect has no side effect.
For achieving the above object, the present invention has adopted following technical scheme:
A kind of pharmaceutical composition of treating hyperlipemia; Calculate according to components by weight percent, the formulation by weight of medicine is following: Herb Gynostemmae Pentaphylli 10-30 part, Fructus Crataegi 10-30 part, Flos Chrysanthemi Indici 15-60 part, Radix Salviae Miltiorrhizae 10-40 part, Cortex Eucommiae 10-40 part, Radix Rehmanniae 8-30 part, Radix Rumicis 15-60 part.
Specifically, described pharmaceutical composition, the formulation by weight of medicine is following: Herb Gynostemmae Pentaphylli 12-25 part, Fructus Crataegi 12-25 part, Flos Chrysanthemi Indici 18-50 part, Radix Salviae Miltiorrhizae 15-30 part, Cortex Eucommiae 15-30 part, Radix Rehmanniae 10-25 part, Radix Rumicis 18-50 part.
More particularly, described pharmaceutical composition, the formulation by weight of medicine is following: 12 parts of Herb Gynostemmae Pentaphylli, 12 parts of Fructus Crataegis, 18 parts of Flos Chrysanthemi Indicis, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Rehmanniae, 18 parts of Radix Rumiciss.
Medicine of the present invention can be processed oral formulations such as tablet, capsule, oral liquid or granule; Be preferably capsule.
Above-mentioned Chinese medicine preparation can be prepared from through following method:
(1), with various Chinese herbal medicine respectively through screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining;
(2), the cream drug of various refinements is pressed the formula proportion weighing, fully mix after the pulverizing, be prepared into various required preparations according to conventional method then.
When medicine of the present invention was processed capsule, with the ointment that previous process steps (1) makes, oven dry, pulverizing were carried out weighing in proportion, are fully mixed, and incapsulate, and promptly get capsule.Specification is: 0.4 gram/grain, usage and dosage: eliminating cold for resuscitation water is swallowed, every day three times, each three.
Medicine of the present invention, Herb Gynostemmae Pentaphylli blood pressure regulation, blood fat reducing, blood sugar regulation, promotion urate excretion are used for blood fat, blood pressure, blood glucose, too high, the high or unusual person of blood uric acid; Fructus Crataegi appetite-stimulating indigestion-relieving, change to stagnate removing food stagnancy, promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm are used to prevent and treat cardiovascular disease, have blood vessel dilating, heart tonifying, coronary blood flow increasing, improve effect such as heart vigor; Flos Chrysanthemi Indici heat-clearing and toxic substances removing, dispelling wind suppressing the hyperactive liver are used for erysipelas, anemopyretic cold, laryngopharynx swelling and pain, hypertension; Radix Salviae Miltiorrhizae promoting blood flow to regulate menstruation, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind cure mainly menoxenia, lump in the abdomen, breast ventral spine pain, dysphoria and insomnia, hepatosplenomegaly, angina pectoris; Cortex Eucommiae invigorating the liver and kidney, bone and muscle strengthening cure mainly that spinal column ache, dribbling urination, uncontrolled urination are itched, hypertension; Radix Rehmanniae heat clearing away, the YIN nourishing of promoting the production of body fluid, nourish blood, control fever due to yin deficiency, quench one's thirst, haematemesis, metrorrhagia, menoxenia, the moon hinder constipation; Radix Rumicis heat-clearing and toxic substances removing, hemostasis, blood stasis dispelling, relieving constipation are used for lung abscess, hemoptysis of pulmonary tuberculosis, acute, chronic hepatitis, constipation.Above-mentioned each medicine is played the effect of promoting blood circulation to remove blood stasis, QI invigorating pain relieving, the blood pressure lowering of relievining asthma altogether, is very beneficial for high, the various symptoms such as blood fat is dense, atherosclerosis, cerebrovascular of blood fat of alleviating and eliminating hyperlipemia and cause.
Below, further set forth the beneficial effect of pharmaceutical composition according to the invention through a series of clinical trial example:
The clinical efficacy of Test Example 1, medicine composite for curing hyperlipemia of the present invention and safety are observed
1.1 case is selected: symptoms such as, atherosclerosis dense with hyperlipidemia, blood fat, cerebral embolism, cerebrovascular are standard, and wherein treatment group is totally 50 examples, wherein male's 25 examples; Women's 25 examples, 35-75 years old ages, 55 years old mean age; The course of disease 6-20 years; Majority is in 6-10 years, and the arteries and veins card was kept the score average 27.5 minutes 18-32 fens;
Matched group is totally 10 examples, male's 5 examples wherein, and women's 5 examples, 30-75 years old ages, average 52.5 years old, the course of disease 3-20 years, majority is in 5-10 years, the arteries and veins card was kept the score average 26.4 minutes 21-33 fens.
1.2 medicament selection and instructions of taking:
The treatment group is taken the capsule that embodiment 1 obtains; Oral, one time 3, three times on the one, 30 days is a course of treatment.
Matched group is taken the atorvastatin calcium tablet, and is oral, one time 2,1 time on the one, every day, maximal dose was no more than 80mg.
1.3 efficacy assessment standard
Recovery from illness: clinical symptoms, sign disappear or basic the disappearance;
Produce effects: clinical symptoms, sign are obviously improved;
Effectively: clinical symptoms, sign are improved.
Invalid: sings and symptoms does not have significant change.
1.4 result of the test:
1.4.1 treatment group and matched group curative effect are relatively
Group | The example number | Clinical recovery | Produce effects | Effectively | Invalid | Effective percentage |
The treatment group | 50 | 9 | 9 | 22 | 10 | 80 |
Matched group | 10 | 0 | 3 | 4 | 3 | 70 |
1.4.2 the relation of the treatment group curative effect and the course of disease
The course of disease | The example number | Clinical recovery | Produce effects | Effectively | Invalid | You Xiao is Shuaied ℅ |
∠ 1 year | 2 | 0 | 1 | 1 | 0 | 100 |
﹥ 1 year | 5 | 2 | 1 | 1 | 1 | 80 |
≧ 2 years | 5 | 1 | 2 | 1 | 1 | 80 |
≧ 3 years | 8 | 2 | 2 | 3 | 1 | 87.5 |
≧ 5 years | 12 | 2 | 1 | 6 | 3 | 75 |
≧ 10 years | 18 | 2 | 2 | 10 | 4 | 77.8 |
Amount to | 50 | 9 | 9 | 22 | 10 | 80 |
1.4.3 treatment group primary symptom curative effect
1.4.4 safety is observed: during the medication of treatment group, toxic and side effects and untoward reaction do not occur.
Above-mentioned test can find out that situation such as headache and dizzy, tinnitus dim eyesight alleviates and progressively disappearance after patient's medication, and the patient feels well, and mental status is good.Total effective rate reaches more than 96%, compares with the Western medicine Atorvastatin calcium, and curative effect is better.Explain that symptoms such as the present composition is dense in treatment hyperlipemia and the blood fat that causes thereof, atherosclerosis have curative effect preferably, and treatment is organized 50 examples untoward reaction and toxic and side effects is taken place without exception.Product is easy to use, safe, advises the clinical use that provides.
Test Example 2, specific embodiment (clinical case)
2.1 sieve family power, the man, 32 years old, hyperlipemia, I go to a doctor in May, 2007; Western medicine diagnose is slight hyperlipemia, and tcm diagnosis is a stagnation of turbid phlegm in middle-JIAO disease, and patient's bodily form is fat, only sees symptom: the extremity asthenia; Feeling of oppression and fullness in the chest and epigastrium, abdominal distension and anorexia, big loose stool is thin, obesity; Palpitation and dizziness, there is indentation on the corpulent tongue limit, greasy fur, rolling pulse.Patient's readme, above-mentioned symptom had for 3 years, had seen Western medicine, and Western medicine was taken atorvastatin or zhibituo film; The commentaries on classics of always not getting better, even some uncomfortable reactions also appear, combine the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs principle of the traditional Chinese medical science according to patient's the state of an illness; Adopt the method for resolving phlegm lowering turbidity, let the patient take 1 course of treatment of capsule that the present composition is processed, patient's reflex is looked into behind the two weeks; Above-mentioned symptom all has and alleviates, continue to take 3 courses of treatment after, recover as before.
2.2 what Changhong, woman, 35 years old, people from Kweiyang, Guizhou; Hyperlipemia mid-term,, go to a doctor patient's readme in October, 2007: oneself feel always that mood is irritated at me; Limbs fatigue, and the intermittent pain of side of body rib distension, more serious is that menstruation is uncomfortable always in the period of nearest three, two treatment are treated and are diagnosed as the hyperlipemia second phase to Kweiyang; Ate medicines such as SHANZHAN JIANGZHI PIAN and atorvastatin, effect is not that ideal also has other reactions once in a while, combines its actual state of an illness according to patient's readme; The principle utilization of following tcm treatment according to syndrome differentiation is hoped, hears, is asked, palpation is disconnected, and the patient belongs to stagnation of liver-QI with deficiency of the spleen disease, and the tablet that utilizes the present composition to process is treated it; The patient comes to check after the course of treatment, and above-mentioned symptom disappears basically, continues to take this product of 3 courses of treatment; Patient's incoming call is expressed thanks after two months, and is proper because it maintains always, so far not recurrence.
2.3 Mrs Yang, 65 years old, the retirement doctor of Zun Yi hospital; In October, 2007, I went to a doctor, patient's readme: suffer from hypertension, hyperlipidemia for many years through hospital diagnosis, the multiple disease of atherosclerosis; All taking other Western medicine, Chinese medicine always, but be exactly the treatment that does not obtain essence.We in conjunction with the actual state of an illness, follow the principle of the tcm treatment according to syndrome differentiation four methods of diagnosis according to patient's readme, and diagnosing patients belongs to deficiency of liver-yin and kidney-yin disease, cardinal symptom: have a dizzy spell soreness and weakness of waist and knees; Insomnia and dreamful sleep, tinnitus is forgetful, and dry throat is dysphoria in chestpalms-soles; Association's pain is seen red night sweat, the red few tongue of tongue, thready rapid pulse.The granule processed of the utilization present composition carries out the tracing type treatment, 5 the course of treatment above-mentioned symptom turn for the better by and large.
2.4 Wang Si is happy, man, 53 years old, V-type hyperlipoproteinemia.Come to go to a doctor patient's readme, " often feeling the especially extremity of being afraid of cold; soreness of the waist and knees, loose stool, the dim eyesight of abdominal distension and anorexia tinnitus; abdominal distention is not relaxed, the fat white, slippery and moist fur of light red tongue, deep-thready pulse " in October, 2008; At other hospital diagnosis is " V-type hyperlipemia ", and it is countless to take Western medicine Chinese medicine, is exactly not obtain basic improvement.According to patient's readme, follow the principle of tcm treatment according to syndrome differentiation in conjunction with conditions of patients, diagnosis belongs to spleen deficiency syndrome, adopts the method for warming and recuperating the spleen and kidney, and the capsule that utilizes the present composition to process is treated, and the patient is as excellent as before after 5 courses of treatment.
2.5 Liu Yong is southern, man, 60 years old, the cerebrovascular that hyperlipemia causes.I go to a doctor in October, 2009, am diagnosed as qi depression to blood stasis disease, cardinal symptom: breast side of body feeling of distension and oppression, the side of body is mass in the abdomen twinge tenderness down, susceptible to lose temper due to restlessness, limbs are unsuccessful, obesity, the bitter taste xerostomia, night unable to fall asleep, purplish tongue is dark or see ecchymosis, deep and hesitant pulse.Adopt blood circulation promoting and blood stasis dispelling, the method for promoting the circulation of QI to relieve pain, the oral liquid that utilizes the present composition to process is treated; After the course of treatment patient come checks, take a favorable turn slightly, continue to take distending pain in the chest and hypochondrium after three courses of treatment; The symptom of not falling asleep night take a favorable turn, and reuse is after three courses of treatment, and limbs are unsuccessful; The symptom of obesity takes a turn for the better to some extent, continue half a year after the patient come to thank in person, physical recovery is as before.
Pharmaceutical composition of the present invention is through above-mentioned evidence; Effect with promoting blood circulation to remove blood stasis, QI invigorating pain relieving, the blood pressure lowering of relievining asthma; To hyperlipemia, especially high, the symptoms such as symptom such as blood fat is dense, atherosclerosis, cerebrovascular of the caused blood fat of hyperlipemia have curative effect preferably.Effect is remarkable, and has no side effect, for the medication of hyperlipemia provides another excellent selection.
The specific embodiment
Do bright specifically below in conjunction with implementing to the present invention.
Embodiment 1:
Herb Gynostemmae Pentaphylli 12g, Fructus Crataegi 12g, Flos Chrysanthemi Indici 18g, Radix Salviae Miltiorrhizae 15g, Cortex Eucommiae 15g, Radix Rehmanniae 10g, Radix Rumicis 18g
Method for preparing: (1), with various Chinese herbal medicine respectively through screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, oven dry, pulverizing;
(2), the cream drug of various refinements is pressed the formula proportion weighing, oven dry, pulverize, carry out weighing in proportion, fully mix, incapsulate, promptly get capsule.0.4 gram/grain.
Usage and dosage: oral, every day three times, each three.
Embodiment 2:
Herb Gynostemmae Pentaphylli 10g, Fructus Crataegi 10g, Flos Chrysanthemi Indici 15g, Radix Salviae Miltiorrhizae 10g, Cortex Eucommiae 10g, Radix Rehmanniae 8g, Radix Rumicis 15g.
Method for preparing: (1), with various Chinese herbal medicine respectively through screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, oven dry, pulverizing;
(2), the cream drug of various refinements is pressed the formula proportion weighing, fully mix after the pulverizing, add starch 1:1 then and mix; Crushed after being dried becomes fine powder, sieves, and the ethanol with 85% is wetting agent; The system granule, 60-70 ℃ of drying adds 2% Pulvis Talci uniform mixing; Be pressed into tablet, the 0.4g/ sheet.
Usage and consumption: oral, every day three times, each 3.
Embodiment 3:
Herb Gynostemmae Pentaphylli 30g, Fructus Crataegi 30g, Flos Chrysanthemi Indici 60g, Radix Salviae Miltiorrhizae 40g, Cortex Eucommiae 40g, Radix Rehmanniae 30g, Radix Rumicis 60g.
Method for preparing: the material of getting it filled, through screening, the process of preparing Chinese medicine, steaming and decocting, dry, remove by filter impurity after being ground into coarse powder, take by weighing medicine by formula proportion, add 6 times of water gagings and decoct and extract each 1 hour 2 times; Extracting solution merges, and filters, and filtrating concentrates, and will filtrate under agitation to add ethanol and make that to contain that alcohol measures be 50%, leaves standstill 12 hours; Filter, concentrate, concentrate the back simple syrup and add to sugar content 10%, add 0.2% sodium benzoate, boil dissolving; Adding distil water is to full dose, and mixing filters, and oral liquid is processed in embedding.10ml/ props up.
Usage and consumption: oral, three times on the one, each 10ml.
Embodiment 4:
Herb Gynostemmae Pentaphylli 25g, Fructus Crataegi 25g, Flos Chrysanthemi Indici 50g, Radix Salviae Miltiorrhizae 30g, Cortex Eucommiae 30g, Radix Rehmanniae 25g, Radix Rumicis 50g.
Method for preparing: (1), with various Chinese herbal medicine respectively through screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, oven dry, pulverizing;
(2), the cream drug of various refinements is pressed the formula proportion weighing, fully mix, add a certain amount of starch and microcrystalline Cellulose then, process capsule.0.4 gram/grain.
Usage and dosage: oral, every day three times, each three.
Embodiment 5:
Herb Gynostemmae Pentaphylli 20g, Fructus Crataegi 20g, Flos Chrysanthemi Indici 40g, Radix Salviae Miltiorrhizae 25g, Cortex Eucommiae 25g, Radix Rehmanniae 20g, Radix Rumicis 40g.
Method for preparing: (1), with various Chinese herbal medicine respectively through screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, oven dry, pulverizing;
(2), the cream drug of various refinements is pressed the formula proportion weighing, it is an amount of to add dextrin, cane sugar powder or lactose, uniform mixing, and 60-70 ℃ of drying, granule is processed in packing.The 10g/ bag.
Usage and consumption: boiled water is taken after mixing it with water, and three times on the one, each 10-20g.
Claims (8)
1. pharmaceutical composition of treating hyperlipemia, it is characterized in that: the formulation by weight of medicine is following: Herb Gynostemmae Pentaphylli 10-30 part, Fructus Crataegi 10-30 part, Flos Chrysanthemi Indici 15-60 part, Radix Salviae Miltiorrhizae 10-40 part, Cortex Eucommiae 10-40 part, Radix Rehmanniae 8-30 part, Radix Rumicis 15-60 part.
2. the pharmaceutical composition of treatment hyperlipemia according to claim 1 is characterized in that: the formulation by weight of medicine is following: Herb Gynostemmae Pentaphylli 12-25 part, Fructus Crataegi 12-25 part, Flos Chrysanthemi Indici 18-50 part, Radix Salviae Miltiorrhizae 15-30 part, Cortex Eucommiae 15-30 part, Radix Rehmanniae 10-25 part, Radix Rumicis 18-50 part.
3. the pharmaceutical composition of treatment hyperlipemia according to claim 1 is characterized in that: the formulation by weight of medicine is following: 12 parts of Herb Gynostemmae Pentaphylli, 12 parts of Fructus Crataegis, 18 parts of Flos Chrysanthemi Indicis, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Rehmanniae, 18 parts of Radix Rumiciss.
4. according to the pharmaceutical composition of the arbitrary described treatment hyperlipemia of claim 1-3, it is characterized in that: method for preparing is:
(1), with various Chinese herbal medicine respectively through screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining;
(2), the cream drug of various refinements is pressed the formula proportion weighing, fully mix after the pulverizing, be prepared into various required preparations according to conventional method then.
5. the pharmaceutical composition of treatment hyperlipemia according to claim 4 is characterized in that: said compositions can be processed tablet, capsule, oral liquid or granule.
6. the pharmaceutical composition of treatment hyperlipemia according to claim 5 is characterized in that: said preparation capsule.
7. the pharmaceutical composition of treatment hyperlipemia according to claim 5 is characterized in that: the method for preparing of capsule is:
(1), with various Chinese herbal medicine respectively through screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining;
(2), the ointment that makes of previous process steps (1), oven dry, pulverize, carry out weighing in proportion, fully mix, incapsulate, promptly get capsule; Specification is: 0.4 gram/grain, usage and dosage: eliminating cold for resuscitation water is swallowed, every day three times, each three.
8. like the pharmaceutical composition of the arbitrary described treatment hyperlipemia of claim 1-3, it is characterized in that medicine is in the treatment hyperlipemia and the blood fat that causes is high, blood fat is dense, the purposes in the cerebrovascular, atherosclerosis, peripheral arterial disease.
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101755973A (en) * | 2010-01-24 | 2010-06-30 | 徐继斌 | Three highs (hypertension, hyperlipidemia and hypertension) lowering and fat dissolving health protection tea prepared by taking gynostemma pentaphylla as main raw material |
CN101890133A (en) * | 2010-07-09 | 2010-11-24 | 向文忠 | Medicine for lowering high blood pressure |
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2012
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101755973A (en) * | 2010-01-24 | 2010-06-30 | 徐继斌 | Three highs (hypertension, hyperlipidemia and hypertension) lowering and fat dissolving health protection tea prepared by taking gynostemma pentaphylla as main raw material |
CN101890133A (en) * | 2010-07-09 | 2010-11-24 | 向文忠 | Medicine for lowering high blood pressure |
Non-Patent Citations (1)
Title |
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梁凤莲等: "高脂血症的中医药辨证论治", 《光明中医》 * |
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Application publication date: 20121107 |