CN104840551A - Hypertension relieving mulberry leaf Chinese medicine preparation and preparing method - Google Patents
Hypertension relieving mulberry leaf Chinese medicine preparation and preparing method Download PDFInfo
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- 239000003814 drug Substances 0.000 title claims abstract description 54
- 206010020772 Hypertension Diseases 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims abstract description 30
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- 235000008708 Morus alba Nutrition 0.000 title abstract 4
- 241000222336 Ganoderma Species 0.000 claims abstract description 14
- 244000303040 Glycyrrhiza glabra Species 0.000 claims abstract description 6
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 6
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 6
- 235000011477 liquorice Nutrition 0.000 claims abstract description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 30
- 238000009835 boiling Methods 0.000 claims description 20
- 230000001631 hypertensive effect Effects 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
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- 229940079593 drug Drugs 0.000 claims description 11
- 239000012153 distilled water Substances 0.000 claims description 10
- 239000000706 filtrate Substances 0.000 claims description 10
- 238000001914 filtration Methods 0.000 claims description 10
- 239000002994 raw material Substances 0.000 claims description 8
- 239000000243 solution Substances 0.000 claims description 6
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 5
- 229930006000 Sucrose Natural products 0.000 claims description 5
- 230000002421 anti-septic effect Effects 0.000 claims description 5
- 238000004140 cleaning Methods 0.000 claims description 5
- 239000008187 granular material Substances 0.000 claims description 5
- 235000012907 honey Nutrition 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 5
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- 238000007654 immersion Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 9
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- 231100000869 headache Toxicity 0.000 abstract description 2
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 235000014493 Crataegus Nutrition 0.000 abstract 1
- 241001092040 Crataegus Species 0.000 abstract 1
- 240000002045 Guettarda speciosa Species 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 1
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- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a hypertension relieving mulberry leaf Chinese medicine preparation, which is prepared from the following ingredients in parts by weight: 100 to 120 parts of liquorice, 160 to 180 parts of lucid ganoderma, 100 to 120 parts of scutellaria baicalensis, 70 to 90 parts of hawthorns, 180 to 200 parts of cassia seeds, 140 to 160 parts of Angelica and 180 to 300 parts of mulberry leaves. A decoction of the hypertension relieving mulberry leaf Chinese medicine preparation is applicable to hypertension symptoms; the symptoms such as dizziness and headache due to hypertension can be fast relieved; in addition, heat clearing and internal heat clearing effects are achieved; the effect is good; toxic and side effects are small; the body health is maintained.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically the hypertensive Folium Mori Chinese medicine preparation of a kind of alleviation and preparation method.
Background technology
Along with the change with dietary structure that improves constantly of our people's living standard, occur increasing " affluenza ", as hypertension, diabetes, cerebral infarction wait indefinitely all with dietary structure close relation, and essential hypertension to become in modern China person in middle and old age group the most a kind of disease, high disorders of blood can cause the pathologic of each organ blood vessel of whole body to change.Current China has 1.8 hundred million hyperpietics, hypertensive alleviation is lifelong concerning most of hyperpietic, because of the disequilibrium that individual household economy is taken in, determine alleviation expense and will affect hypertensive treatment significantly, Chinese medicine is for alleviating hypertensive medicine, owing to having, expense is low, side effect is little, eutherapeutic feature, therefore favors by people very much.
Summary of the invention
The object of the present invention is to provide the hypertensive Folium Mori Chinese medicine preparation of little, the eutherapeutic alleviation of a kind of toxic and side effects and preparation method, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
The hypertensive Folium Mori Chinese medicine preparation of a kind of alleviation, is formed by the preparation of raw material of following weight portion: 100 ~ 120 parts, Radix Glycyrrhizae, Ganoderma 160 ~ 180 parts, Radix Scutellariae 100 ~ 120 parts, Fructus Crataegi 70 ~ 90 parts, Semen Cassiae 180 ~ 200, Radix Angelicae Sinensis 140 ~ 160 parts, 280 ~ 300 parts, Folium Mori.
The hypertensive Folium Mori Chinese medicine preparation of described alleviation, is made up of raw material medicine: 100 parts, Radix Glycyrrhizae, Ganoderma 170 parts, Radix Scutellariae 110 parts, Fructus Crataegi 80 parts, Semen Cassiae 190 parts, Radix Angelicae Sinensis 150 parts, 290 parts, Folium Mori.
The hypertensive Folium Mori Chinese medicine preparation of described alleviation, concrete preparation process is as follows:
Extracting liquorice 100 parts, Ganoderma 170 parts, Radix Scutellariae 110 parts, Fructus Crataegi 80 parts, Semen Cassiae 190 parts, Radix Angelicae Sinensis 150 parts, 220 parts, Folium Mori, cleaning is dried, be ground into granule, add water immersion 60 ~ 90min at the temperature of 50 ~ 70 DEG C, then use soak by water twice, the distilled water that first time adds crude drug 12 times amount, continue to decoct 30min after intense fire is fried boiling, and then slow fire boiling 3 ~ 5h, get isolated by filtration of boiling medicine; And then add the distilled water of crude drug 8 times amount, decoct 1 ~ 2h, get secondary isolated by filtration of boiling medicine, the relative density that filtrate carries out being concentrated into concentrated solution at the temperature of 65 ~ 75 DEG C is 1.10 ~ 1.20, then the content of ethanol in liquid is made to be 60% adding ethanol, mix homogeneously, leaves standstill 20 ~ 24h, filters and regains ethanol; Filtrate is condensed into the extractum containing solid weight 68 ~ 72%, adds sucrose 20%, refined honey 12%, antiseptic 2%, stock solution embedding, irradiation sterilization, packed products, hypertensive Folium Mori Chinese medicine preparation must be alleviated.
Instructions of taking: every day is early, middle and late respectively takes once, and a dose is 10ml, 15 days courses for the treatment of, manyly after taking medicine took effect at 15 ~ 20 days, and 3 ~ 4 courses for the treatment of cure.
The pharmacological action of the raw material of Chinese medicine selected by the present invention: Radix Glycyrrhizae: to be slightly cold, bitter, enters the heart, Liver Channel, and dispel addiction, menstruction regulating and pain relieving, the removing heat from blood of invigorating blood circulation disappears pain, clearing away heart-fire for tranquillization; Ganoderma: sweet, flat, GUIXIN, lung, liver, kidney channel, tonify deficiency is calmed the nerves, expelling phlegm for arresting cough; Semen Cassiae: sweet, bitter, be slightly cold, returns large intestine channel, liver heat removing and eyesight improving, loosening bowel to relieve constipation; Fructus Ligustri Lucidi: sweet, bitter, cool, returns liver, kidney channel, liver and kidney tonifying, improving eyesight, clearind deficient heat; Radix Angelicae Sinensis: sweet, pungent, warm, returns liver, the heart, spleen channel, blood-supplementing blood-nourishing, Huoxue San " are tired, regulating menstruation, pain relieving, intestine moistening; Folium Mori: bitter, cold in nature, GUIXIN, liver, spleen, lung meridian, clearing away summer-heat, improving eyesight removing toxic substances, QI invigorating recover from fatigue, and blood fat reducing, solution labor clear away heart-fire, and enhance metabolism; All medicines play altogether strong do not learn invigorate blood circulation, merit that good for heart and brain, blood pressure lowering are dizzy clearly.Decoction of the present invention is applicable to hypertension symptom, can remove rapidly the symptoms such as the dizzy headache of caused by hypertension, and heat clearing away and internal heat reducing, and effective, toxic and side effects is little, keeps health.Points for attention: anemia of pregnant woman is forbidden.
Detailed description of the invention
Embodiment 1
Alleviate hypertensive Folium Mori Chinese medicine preparation
Be made up of raw material medicine: 100 parts, Radix Glycyrrhizae, Ganoderma 160 parts, Radix Scutellariae 100 parts, Fructus Crataegi 70 parts, Semen Cassiae 180 parts, Radix Angelicae Sinensis 140 parts, 280 parts, Folium Mori.
Concrete preparation process is as follows:
Extracting liquorice 100 parts, Ganoderma 160 parts, Radix Scutellariae 100 parts, Fructus Crataegi 70 parts, Semen Cassiae 180 parts, Radix Angelicae Sinensis 140 parts, 280 parts, Folium Mori, cleaning is dried, be ground into granule, add water and soak 70min at the temperature of 60 DEG C, then use soak by water twice, the distilled water that first time adds crude drug 12 times amount, continue to decoct 30min after intense fire is fried boiling, and then slow fire boiling 3h, get isolated by filtration of boiling medicine; And then add the distilled water of crude drug 8 times amount, decoct 2h, get secondary isolated by filtration of boiling medicine, the relative density that filtrate carries out being concentrated into concentrated solution at the temperature of 70 DEG C is 1.10 ~ 1.20, then the content of ethanol in liquid is made to be 60% adding ethanol, mix homogeneously, leaves standstill 24h, filters and regains ethanol; Filtrate is condensed into the extractum containing solid weight 70%, adds sucrose 20%, refined honey 12%, antiseptic 2%, stock solution embedding, irradiation sterilization, packed products, hypertensive Folium Mori Chinese medicine preparation must be alleviated.
Embodiment 2
Alleviate hypertensive Folium Mori Chinese medicine preparation
Be made up of raw material medicine: 110 parts, Radix Glycyrrhizae, Ganoderma 170 parts, Radix Scutellariae 110 parts, Fructus Crataegi 80 parts, Semen Cassiae 190 parts, Radix Angelicae Sinensis 150 parts, 290 parts, Folium Mori.
Concrete preparation process is as follows:
Extracting liquorice 110 parts, Ganoderma 170 parts, Radix Scutellariae 110 parts, Fructus Crataegi 80 parts, Semen Cassiae 190 parts, Radix Angelicae Sinensis 150 parts, 290 parts, Folium Mori, cleaning is dried, be ground into granule, add water and soak 70min at the temperature of 60 DEG C, then use soak by water twice, the distilled water that first time adds crude drug 12 times amount, continue to decoct 30min after intense fire is fried boiling, and then slow fire boiling 3h, get isolated by filtration of boiling medicine; And then add the distilled water of crude drug 8 times amount, decoct 2h, get secondary isolated by filtration of boiling medicine, the relative density that filtrate carries out being concentrated into concentrated solution at the temperature of 70 DEG C is 1.10 ~ 1.20, then the content of ethanol in liquid is made to be 60% adding ethanol, mix homogeneously, leaves standstill 24h, filters and regains ethanol; Filtrate is condensed into the extractum containing solid weight 70%, adds sucrose 20%, refined honey 12%, antiseptic 2%, stock solution embedding, irradiation sterilization, packed products, hypertensive Folium Mori Chinese medicine preparation must be alleviated.
Embodiment 3
Alleviate hypertensive Folium Mori Chinese medicine preparation
Be made up of raw material medicine: 120 parts, Radix Glycyrrhizae, Ganoderma 180 parts, Radix Scutellariae 120 parts, Fructus Crataegi 90 parts, Semen Cassiae 200 parts, Radix Angelicae Sinensis 160 parts, 300 parts, Folium Mori.
Concrete preparation process is as follows:
Extracting liquorice 120 parts, Ganoderma 180 parts, Radix Scutellariae 120 parts, Fructus Crataegi 90 parts, Semen Cassiae 200 parts, Radix Angelicae Sinensis 160 parts, 300 parts, Folium Mori, cleaning is dried, be ground into granule, add water and soak 70min at the temperature of 60 DEG C, then use soak by water twice, the distilled water that first time adds crude drug 12 times amount, continue to decoct 30min after intense fire is fried boiling, and then slow fire boiling 3h, get isolated by filtration of boiling medicine; And then add the distilled water of crude drug 8 times amount, decoct 2h, get secondary isolated by filtration of boiling medicine, the relative density that filtrate carries out being concentrated into concentrated solution at the temperature of 70 DEG C is 1.10 ~ 1.20, then the content of ethanol in liquid is made to be 60% adding ethanol, mix homogeneously, leaves standstill 24h, filters and regains ethanol; Filtrate is condensed into the extractum containing solid weight 70%, adds sucrose 20%, refined honey 12%, antiseptic 2%, stock solution embedding, irradiation sterilization, packed products, hypertensive Folium Mori Chinese medicine preparation must be alleviated.
Embodiment 4
Clinical trial
(1) subjects: adopt the present invention to treat 100 routine patients altogether, Qi Zhongnan: 55 examples, female 45 example; The oldest person 70 years old, age reckling 30 years old.
(2) Therapeutic Method: every day is early, middle and late respectively takes once, and a dose is 10ml, 15 days courses for the treatment of, 3 ~ 4 recoveries from illness courses for the treatment of.
(3) blood pressure curative effect determinate standard: 1. effective, diastolic pressure more than decline lOmmHg, and reach normal range; Though 2. diastolic pressure does not drop to normally, own decline 20mmHg or more; 3. diastolic pressure comparatively treats the front 10 ~ 19mmHg that declines, but does not reach normal range; 4. systolic pressure comparatively treats front more than decline 30mmHg; 5. invalidly above standard person is not reached.
Therapeutic effect of syndrome criterion
A () effective clinical symptoms, sign are obviously improved, syndrome integral reduces >=70%;
B () effective clinical symptom, sign all take a favorable turn, syndrome integral reduces >=30%;
C () invalid clinical symptoms, sign are not improved, even increase the weight of, syndrome integral reduces less than 30%.
(d) therapeutic outcome: how to take effect at 30 ~ 50 days after taking medicine in the routine case of patient 100,3 ~ 4 courses for the treatment of cure; Wherein cure 70 examples, effective 22 examples, effective 5 examples, invalid 3 examples, total effective rate reaches 97%.
Embodiment 5
Model case: Zhang, man, 55 years old is hypertension by hospital diagnosis, healing in 3 months of taking medicine.
Embodiment 6
Model case: Liu, man, 60 years old is hypertension by hospital diagnosis, healing in 4 months of taking medicine.
Embodiment 7
Model case: Lin, female, 50 years old, high pressure 180, low pressure 120, healing in 4 months of taking medicine.
Claims (3)
1. alleviate hypertensive Folium Mori Chinese medicine preparation for one kind, it is characterized in that, formed by the preparation of raw material of following weight portion: 100 ~ 120 parts, Radix Glycyrrhizae, Ganoderma 160 ~ 180 parts, Radix Scutellariae 100 ~ 120 parts, Fructus Crataegi 70 ~ 90 parts, Semen Cassiae 180 ~ 200, Radix Angelicae Sinensis 140 ~ 160 parts, 180 ~ 300 parts, Folium Mori.
2. the hypertensive Folium Mori Chinese medicine preparation of alleviation according to claim 1, is characterized in that, be made up of raw material medicine: 100 parts, Radix Glycyrrhizae, Ganoderma 170 parts, Radix Scutellariae 110 parts, Fructus Crataegi 80 parts, Semen Cassiae 190 parts, Radix Angelicae Sinensis 150 parts, 220 parts, Folium Mori.
3. the hypertensive Folium Mori Chinese medicine preparation of alleviation according to claim 1 and 2, it is characterized in that, concrete preparation process is as follows: extracting liquorice 100 parts, Ganoderma 170 parts, Radix Scutellariae 110 parts, Fructus Crataegi 80 parts, Semen Cassiae 190 parts, Radix Angelicae Sinensis 150 parts, 220 parts, Folium Mori, cleaning is dried, be ground into granule, add water immersion 60 ~ 90min at the temperature of 50 ~ 70 DEG C, then soak by water twice is used, add the distilled water of crude drug 12 times amount for the first time, continue to decoct 30min after intense fire is fried boiling, and then slow fire boiling 3 ~ 5h, get isolated by filtration of boiling medicine; And then add the distilled water of crude drug 8 times amount, decoct 1 ~ 2h, get secondary isolated by filtration of boiling medicine, the relative density that filtrate carries out being concentrated into concentrated solution at the temperature of 65 ~ 75 DEG C is 1.10 ~ 1.20, then the content of ethanol in liquid is made to be 60% adding ethanol, mix homogeneously, leaves standstill 20 ~ 24h, filters and regains ethanol; Filtrate is condensed into the extractum containing solid weight 68 ~ 72%, adds sucrose 20%, refined honey 12%, antiseptic 2%, stock solution embedding, irradiation sterilization, packed products, hypertensive Folium Mori Chinese medicine preparation must be alleviated.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105106308A (en) * | 2015-09-16 | 2015-12-02 | 程俊 | Arrowroot flour traditional Chinese medicine preparation for relieving hypertension and preparation method |
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2015
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Application publication date: 20150819 |