CN105769957B - Pseudo-ginseng powder prepared from snow pears and rice water, preparation of pseudo-ginseng powder and preparation method - Google Patents
Pseudo-ginseng powder prepared from snow pears and rice water, preparation of pseudo-ginseng powder and preparation method Download PDFInfo
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Abstract
The invention provides pseudo-ginseng powder prepared from snow pears and rice water, a preparation of the pseudo-ginseng powder and a preparation method.The pseudo-ginseng powder prepared from the snow pears and the rice water is prepared from, by weight, 5-100 parts of pseudo-ginseng, 5-60 parts of snow pears and 5-100 parts of rice water.The pseudo-ginseng powder prepared from the snow pears and the rice water can relieve side effects of thirst, astriction, weakness of limbs, dysphoria with smothery sensation and the like generated after pseudo-ginseng is taken, the effects of strengthening the middle warmer, strengthening the spleen and stomach, promoting secretion of saliva or body fluid and lubricating the intestines are added, pseudo-ginseng relieves losses of body fluid while dispersing stasis and stopping bleeding, no fever or dryness heat is generated, the bitter taste of pseudo-ginseng is relieved, and people can more easily take the pseudo-ginseng powder.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of snow pear water in which rice has been washed Radix Notoginseng powder and its preparation and preparation side
Method.
Background technology
Pseudo-ginseng also known as pseudo-ginseng, the dry root of panax araliaceae plant Panax notoginseng (Burk.) F.H.Chen
And rhizome, main product is in Yunnan Wenshan Prefecture, therefore named mountain of papers pseudo-ginseng.Chinese medicine pseudo-ginseng is using its root as medicinal effects, with scattered
The effect of stasis of blood hemostasis, detumescence ding-tong.
Sweet, slight bitter, temperature.Effect, dissipate stasis of blood hemostasis, detumescence ding-tong.Cure mainly for spitting blood, spit blood, bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding,
Traumatism and bleeding, chest and abdomen shouting pain, tumbling and swelling.
A large amount of medical researches prove, pseudo-ginseng can be used to treating traumatism and bleeding, hemostasis, gastrorrhagia, hematuria etc. it is various it is inside and outside go out
Mass formed by blood stasis；Expansion of blood vessels, thrombus improve microcirculation, prevention and treatment high fat of blood, cholesterol increase, coronary heart diseases and angina pectoris,
The cardiovascular and cerebrovascular diseases such as apoplexy sequela；The hepatopathys such as fatty liver, liver fibrosis and lose blood, postpartum, the reason such as prolonged illness cause
Body void card.Pseudo-ginseng is suppressing anticancer, anti-oxidant whitening to cardiovascular system, to body material's metabolism, to nervous system, auxiliary
The colour of skin, anti-aging and help many-sided pharmacological action such as strong, makes it extensively should preventing and treating various diseases, health care aspect
With.
But because pseudo-ginseng is warm in nature, easily consumption hinders body fluid, causes the disease of the deficiency of Yin.Show as taking and occur after pseudo-ginseng thirsty, just
Secret, weakness of limbs, dysphoria with smothery sensation, evening take the side effects such as insomnia.
The content of the invention
In order to overcome scarce limit of the prior art, the invention provides a kind of snow pear water in which rice has been washed Radix Notoginseng powder, it can change
It is kind to take the aspect side effect such as the thirsty of generation, constipation, weakness of limbs, dysphoria with smothery sensation after pseudo-ginseng, increase bowl spares strengthening the spleen and stomach, profit of promoting the production of body fluid
Effect of intestines, makes the consumption that pseudo-ginseng mitigates body fluid while dissipate stasis of blood hemostasis hinder not heat dryness-heat, while improve pseudo-ginseng bitter taste mouthfeel,
People are made to be easier to take.The present invention is realized by following technical scheme.
On the one hand, the invention provides a kind of snow pear water in which rice has been washed Radix Notoginseng powder, its be by following component by ratio of weight and the number of copies
Made by：5～100 parts of pseudo-ginseng, 5～60 parts of snow pear, 5～100 parts of water in which rice has been washed；It is preferred that 20～100 parts of pseudo-ginseng, 5～40 parts of snow pear,
5～80 parts of water in which rice has been washed；More preferably 30～70 parts of pseudo-ginseng, 5～20 parts of snow pear, 40～80 parts of water in which rice has been washed；Most preferably pseudo-ginseng 40～70
Part, 10～20 parts of snow pear, 50～70 parts of water in which rice has been washed.
The snow pear water in which rice has been washed Radix Notoginseng powder of the present invention is prepared by the method for comprising the steps：
1）It is meal that pseudo-ginseng cleaning is smashed；
2）Fresh snow pear squeezing is chosen, filtration adds 2～4 times of clear water to obtain snow pear juice；
3）The water in which rice has been washed that the clear water elutriation of selection rice obtains white opacity is standby；
4）By step 2）With 3）It is well mixed that to obtain snow pear water in which rice has been washed standby；
5）Pseudo-ginseng meal after smashing is put into into step 4）Temperature control is in 10～20 DEG C of leachings in the snow pear water in which rice has been washed of preparation
System 2～48 hours, period stirred 1 time every 6 hours so as to is evenly distributed, is impregnated with pseudo-ginseng particle and fully absorbs refined honey rice swill
Water；
6）Notoginseng drying after leaching is made is to water content below 15%；
7）By step 6）Dry pseudo-ginseng is crushed and is obtained final product for impalpable powder.
On the other hand, the invention provides a kind of Chinese medicine preparation, it includes above-mentioned snow pear water in which rice has been washed Radix Notoginseng powder.
Further, present invention also offers the preparation method of the snow pear water in which rice has been washed Radix Notoginseng powder, it includes following step
Suddenly：
1）It is meal that pseudo-ginseng cleaning is smashed；
2）Fresh snow pear squeezing is chosen, filtration adds 2～4 times of clear water to obtain snow pear juice；
3）The water in which rice has been washed that the clear water elutriation of selection rice obtains white opacity is standby；
4）By step 2）With 3）It is well mixed that to obtain snow pear water in which rice has been washed standby；
5）Pseudo-ginseng meal after smashing is put into into step 4）Temperature control is in 10～20 DEG C of leachings in the snow pear water in which rice has been washed of preparation
System 2～48 hours, period stirred 1 time every 6 hours so as to is evenly distributed, is impregnated with pseudo-ginseng particle and fully absorbs refined honey rice swill
Water；
6）Notoginseng drying after leaching is made is to water content below 15%；
7）By step 6）Dry pseudo-ginseng is crushed and is obtained final product for impalpable powder.
Pharmacological effect side's solution of snow pear water in which rice has been washed Radix Notoginseng powder of the present invention is as follows：
Snow pear：Nature and flavor are sweet, micro- acid, tremble with fear；Attach to the lung and stomach meridians.With moisturizing, promote the production of body fluid, heat-clearing effect, be usually used in it is fire excess from yin deficiency,
Dry-heat impairing lung, the auxiliary treatment of injury thirst.According to《Compendium of Materia Medica》Record, " pears person, profit, its property is descending fluent." there is moistening lung
It is clear it is dry, promote the production of body fluid to quench thirst, the effect of nourishing blood and promoting granulation.The traditional Chinese medical science thinks the lung and the large intestine being interior-exteriorly related, thus have while moisturizing clearing lung-heat moisturize it is logical
Just effect, thus the deficiency of Yin is occurred throat is dry, thirsty, intestinal dryness is just dry good effect.
Pseudo-ginseng：Nature and flavor are sweet, slight bitter, temperature, return through Return liver, stomach.The effect of with dissipate stasis of blood hemostasis, detumescence ding-tong.Cure mainly and cough up
Blood, spits blood, and bleeding from five sense organs or subcutaneous tissue is had blood in stool, and uterine bleeding, traumatism and bleeding, chest and abdomen shouting pain is fallen servant and swollen and ache.Just it is acknowledged as with significant since ancient times
Promoting blood circulation and removing blood stasis, detumescence ding-tong effect, the good reputation with " invaluable ", " southern part of the country god grass ".Spitting of blood is cured mainly, is spitted blood, bleeding from five sense organs or subcutaneous tissue, just
Blood, uterine bleeding, traumatism and bleeding, chest and abdomen shouting pain, tumbling and swelling.
Water in which rice has been washed：Nature and flavor are sweet, cool, nontoxic.Can be used to process medicine, can go dry property and and in and laxation effect, nurse one's health spleen
Stomach, heat-clearing stops polydipsia and stops the effects such as polydipsia, diuresis, cool blood, removing toxic substances.
The positive effect of the present invention is：The present invention is, according to theory of traditional Chinese medical science basis, using said medicine compatibility, to make pseudo-ginseng
Prove effective with snow pear water in which rice has been washed mutual restraint between two drugs, snow pear water in which rice has been washed has functions that to promote the production of body fluid to quench thirst, moistening dryness for relaxing bowels relieving restlessness, can reduce pseudo-ginseng
Dry property is warmed, improves the side effects such as thirsty, constipation, heating, insomnia, pseudo-ginseng is not consumed while dissipate stasis of blood hemostasis and hinder body fluid, no
Heat dryness-heat；Improving pseudo-ginseng bitter taste mouthfeel again simultaneously makes people be easier to take.
Specific embodiment
Embodiments below and case application, are only intended to clearly illustrate example of the present invention, and not to this
The restriction of invention.For those of ordinary skill in the art, other can also be made not on the basis of the above description
With the change or variation of form.And the obvious change thus amplified out or change still in protection scope of the present invention
Among.
Embodiment 1：
The preparation method of snow pear water in which rice has been washed Radix Notoginseng powder：
1st, 50g pseudo-ginsengs are taken, the removal of impurity is smashed as meal, the drying 1 hour of 30 DEG C of Jing low temperature, is dried to water content
20%；
2nd, the squeezing of 10g snow pears is taken, filtration adds 20g clear water to obtain snow pear juice standby；
3rd, choosing 30g rice adds 300g clear water to wash by rubbing with the hands repeatedly, filters and obtains water in which rice has been washed；
The 4th, step 2 and 3 are well mixed to obtain snow pear water in which rice has been washed standby；
5th, the pseudo-ginseng raw material being dried step 1 is placed in snow pear water in which rice has been washed and stirs in 20 DEG C of constant temperature leaching system 8 hours, phase
Between every 4 hours stir 1 time so as to be evenly distributed, be impregnated with pseudo-ginseng and fully absorb snow pear water in which rice has been washed；
6th, the pseudo-ginseng that step 5 process is obtained is placed in low-temperature vacuum drying case, the drying 3 hours of 30 DEG C of Jing low temperature is dried
To water content 15%；
7th, smash and obtained final product for impalpable powder.
Embodiment 2：
The preparation method of snow pear water in which rice has been washed Radix Notoginseng powder：
1st, 300g pseudo-ginsengs are taken, the removal of impurity is smashed as meal, the drying 1 hour of 30 DEG C of Jing low temperature, is dried to water content
20%；
2nd, the squeezing of 100g snow pears is taken, filtration adds 200g clear water to obtain snow pear juice standby；
3rd, choosing 150g rice adds 1000g clear water to wash by rubbing with the hands repeatedly, filters and obtains water in which rice has been washed；
The 4th, step 2 and 3 are well mixed to obtain snow pear water in which rice has been washed standby；
5th, the pseudo-ginseng raw material being dried step 1 is placed in snow pear water in which rice has been washed and stirs in 15 DEG C of constant temperature leaching system 12 hours,
Period stirred 1 time every 4 hours so as to is evenly distributed, is impregnated with pseudo-ginseng and fully absorbs snow pear water in which rice has been washed；
6th, the pseudo-ginseng that step 5 process is obtained is placed in low-temperature vacuum drying case, the drying 5 hours of 23 DEG C of Jing low temperature is dried
To water content 13%；
7th, smash and obtained final product for impalpable powder.
Embodiment 3：
The preparation method of snow pear water in which rice has been washed Radix Notoginseng powder：
1st, 100g pseudo-ginsengs are taken, the removal of impurity is smashed as meal, the drying 1 hour of 28 DEG C of Jing low temperature, is dried to water content
20%；
2nd, the squeezing of 80g snow pears is taken, filtration adds 200g clear water to obtain snow pear juice standby；
3rd, choosing 60g rice adds 700g clear water to wash by rubbing with the hands repeatedly, filters and obtains water in which rice has been washed；
The 4th, step 2 and 3 are well mixed to obtain snow pear water in which rice has been washed standby；
5th, the pseudo-ginseng raw material being dried step 1 is placed in snow pear water in which rice has been washed and stirs in 18 DEG C of constant temperature leaching system 8 hours, phase
Between every 4 hours stir 1 time so as to be evenly distributed, be impregnated with pseudo-ginseng and fully absorb snow pear water in which rice has been washed；
6th, the pseudo-ginseng that step 5 process is obtained is placed in low-temperature vacuum drying case, the drying 2 hours of 25 DEG C of Jing low temperature is dried
To water content 14%；
7th, smash and obtained final product for impalpable powder.
Test example 1：Pharmacodynamic Data
To prove that the validity of the invention has carried out pharmacological evaluation in terms of pharmacodynamics, it is reported as follows：
1st, test material
1-1 medicines：Primary Radix Notoginseng powder and snow pear water in which rice has been washed Radix Notoginseng powder, by Jilin Province north domain American Ginseng research Co., Ltd
There is provided, lot number 20151119.Dosage setting by people and animal body surface area equivalent dosage conversions, people's daily maximum dose level
（9g/60kg）Equivalent to mouse 1.2g/kg.Therefore the primary Radix Notoginseng powder of this test setting mouse and snow pear water in which rice has been washed Radix Notoginseng powder dosage
Be 0.6,1.2,2.4g/kg groups, desired concn is configured to 0.5% sodium carboxymethylcellulose during test.
1-2 animals：ICR mouse, 18～22g of body weight, quality certification number：SCXK（It is lucky）2015-0003, is asked in vain by Jilin University
The animal experimental center supply of grace medical college.Raise ground：Bethune medical college of Jilin University animal experimental center.
2nd, test method
ICR mouse 140,18～22g, male and female half and half.7 groups are randomly divided into by sex, body weight, i.e.,：Control group, primary three
The basic, normal, high dosage group of seven powder and the basic, normal, high dosage group of snow pear water in which rice has been washed Radix Notoginseng powder, every group of male and female are each 10.Gavage capacity
20ml/kg is, one time a day, continuous 30 days.In administration 30 days, the equal lumbar injection yellow Jackets 50mg/kg of each group mouse,
Incubation period and the length of one's sleep that record is slept in 30 minutes.
3rd, observation index
Each group observes respectively lower index for 10,20,30 days in administration：
（1）Autonomic activities situation in mouse 10 minutes；
（2）Mouse symptom and sign：The expression of animal, activity（Grab nose, itch etc.）Situation；
（3）The mouse amount of drinking water of 24 hours, urine volume and color, excrement shape etc. change.
4th, result of the test
Mouse autonomic activities is observed respectively within 10,20,30 days, compare with control group in administration, the middle and high dosage of primary Radix Notoginseng powder
Group can substantially increase mouse autonomic activities number of times（p<0.05）, the basic, normal, high dosage group of snow pear water in which rice has been washed Radix Notoginseng powder has no bright
Significant difference is different（p>0.05）, it is shown in Table 1.
Mouse amount of drinking water and urine volume situation of change are observed respectively within 10,20,30 days, compare with control group, primary three in administration
The middle and high dosage group of seven powder can substantially increase mouse amount of drinking water and urine volume in 20,30 days in administration（p<0.05）, snow pear water in which rice has been washed system
The basic, normal, high dosage group of Radix Notoginseng powder has no notable difference（p>0.05）, it is shown in Table 2.
In administration mouse urine volume color, excrement shape, the expression of animal, activity are observed respectively within 10,20,30 days（Grab nose, scabies
Itch）Situation, compares with control group, and the visible mouse expression of the middle and high dosage group of primary Radix Notoginseng powder is irritated, and activity increases, and urine volume increases
It is many, darken, excrement is excluded and reduced, and shape is hard, and the basic, normal, high dosage group of snow pear water in which rice has been washed Radix Notoginseng powder has no substantially poor
It is different, it is shown in Table 3.
In administration 30 days, the synergy to the sleep of threshold dose yellow Jackets is observed, compared with control group, primary pseudo-ginseng
The middle and high dosage group of powder can be obviously prolonged Sleep latency, and curtail sleep（p<0.05）, snow pear water in which rice has been washed Radix Notoginseng powder
Basic, normal, high dosage group has no notable difference（p>0.05 or p<0.01）, it is shown in Table 4.
The impact of the primary Radix Notoginseng powder of table 1 and the present invention to mouse autonomic activities（± S, n=10）
Compare with control group, * p<0.05
The primary Radix Notoginseng powder of table 2 and the present invention affect on 24 hours water uptakes of mouse（± S, n=10）
Compare with control group, * p<0.05
The primary Radix Notoginseng powder of table 3 and the present invention affect on mouse twenty-four-hour urine amount（± S, n=10）
The impact of the primary Radix Notoginseng powder of table 4 and the present invention to mouse yellow Jackets hypnosis（± S, n=10）
Control group compares, * p<0.05, * * p<0.01
5th, conclusion (of pressure testing)
Primary Radix Notoginseng powder can substantially increase mouse autonomic activities number of times, hence it is evident that increase mouse amount of drinking water and urine volume, can make little
Mouse expression is irritated, and activity increases, and hydrouria darkens, and excrement is excluded and reduced, and shape is hard, to threshold dose amobarbital
Sodium sleep has synergy, can be obviously prolonged Sleep latency, and curtails sleep, and points out primary Radix Notoginseng powder continuous oral
1 month, animal can be made the side effects such as thirsty, constipation, insomnia occur.The continuous oral present invention 1 month, has no that obvious animal occurs
The side effects such as thirsty, dysphoria with smothery sensation, constipation, insomnia.
Test example 2：Typical case
1st, certain man, 37 years old, diagnosis：Esophagitis, UGB, spitting blood, black of defecating.
Treatment：3 times a day, and a 3g takes the bleeding reduction after 1 week of primary Radix Notoginseng powder, and spitting blood stops, but causes due to losing blood
, there is dysphoria with smothery sensation, thirsty, constipation symptom in the deficiency of blood.It is secondary.
Effect：The Radix Notoginseng powder for being prepared using the embodiment of the present invention 1 afterwards, often takes 3 grams, and daily 3 use snow pear rice swill of the present invention instead
Dysphoria with smothery sensation, thirsty, constipation symptom are improved after water Radix Notoginseng powder, does not occur any side effect, and disease after continuously taking 21 days yet
Disease recovery from illness.
2nd, certain man, 48 years old, diagnosis：The spitting of blood that pulmonary tuberculosis causes.
Treatment：While with conventional antituberculosis therapy, Radix Notoginseng powder is taken 3 times a day a 3g, disease of spitting blood after taking 1 week
Shape mitigates.But occur in that the side effect that pseudo-ginseng causes：Thirsty, constipation, slight insomnia.
Effect：Subsequently use primary Radix Notoginseng powder instead in the embodiment of the present invention 2 snow pear water in which rice has been washed Radix Notoginseng powder for preparing, take
Thirsty afterwards, constipation, mild insomnia shape disappear.After continuously taking 1 month, spitting of blood symptom is wholly absent, and continues antituberculosis therapy 3
Fully recover after individual month.
3rd, certain man, 50 years old tcm diagnosis：Tcm syndrome differentiation and treatment type of hyperactivity of fire caused by deficiency of YIN blood urine.
Treatment：Compatibility prepared rhizome of rehmannia, cornus, Chinese yam rhizome, Poria cocos, rhizoma alismatis, the root bark of tree peony, the wind-weed, golden cypress.Radix Notoginseng powder is taken after mixing it with water, and daily 3
Secondary, each 3g, after continuously taking 5 days, stops blood urine substantially, but serious constipation occurs, while with thirsty, dysphoria with smothery sensation, four limbs
It is powerless to wait side reaction.
Effect：Afterwards by primary Radix Notoginseng powder this with the snow pear water in which rice has been washed Radix Notoginseng powder in the embodiment of the present invention 3, constipation, dysphoria with smothery sensation,
Thirsty side reaction disappears, and does not occur any side effect after continuously taking 15 days yet, and disease is fully recovered.
Claims (1)
1. a kind of preparation method of snow pear water in which rice has been washed Radix Notoginseng powder, it is characterised in that by 40～70 parts of pseudo-ginseng, 10～20 parts of snow pear,
50～70 parts of water in which rice has been washed is made by weight, comprises the steps：
1）It is meal that pseudo-ginseng cleaning is smashed；
2）Fresh snow pear squeezing is chosen, filtration adds 2～4 times of clear water to obtain snow pear juice；
3）The water in which rice has been washed that the clear water elutriation of selection rice obtains white opacity is standby；
4）By step 2）With 3）It is well mixed that to obtain snow pear water in which rice has been washed standby；
5）Pseudo-ginseng meal after smashing is put into into step 4）In the snow pear water in which rice has been washed of preparation temperature control 10～20 DEG C leaching system 2～
48 hours, period stirred 1 time every 6 hours so as to is evenly distributed, is impregnated with pseudo-ginseng particle and fully absorbs refined honey water in which rice has been washed；
6）Notoginseng drying after leaching is made is to water content below 15%；
7）By step 6）Dry pseudo-ginseng is crushed and is obtained final product for impalpable powder.
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| CN105769957A (en) | 2016-07-20 |
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