CN105769959A - Panax notoginseng preparation prepared from snow pears, rice water and honey, and preparation method - Google Patents
Panax notoginseng preparation prepared from snow pears, rice water and honey, and preparation method Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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Abstract
The invention relates to a panax notoginseng preparation prepared from snow pears, rice water and honey, and also provides a preparation method of the preparation at the same time. According to the preparation and the preparation method, on the basis of theories of traditional Chinese medicine, the drugs are used in coordination, so that panax notoginseng as well as the snow pears, the rice water and the honey is mutually restraint to take effect; the snow pears, the rice water and the honey have effects of nourishing yin, tonifying qi, helping produce saliva and slake thirst, moistening dryness, relaxing the bowels and relieving restlessness, can reduce warm dryness of panax notoginseng and reduce side effects such as thirst, astriction, fever, insomnia and the like, and accordingly, consumption of body fluid and generation of heat and dryness are prevented while effects of dissipation of blood stasis and bleeding stopping of panax notoginseng are achieved; meanwhile, the preparation has effects of nourishing yin and tonifying qi and can improve the bitter taste of panax notoginseng, thereby being more easily taken by people.
Description
Technical field
The present invention relates to the preparation of a kind of pear rice water Mel Radix Notoginseng, the preparation method simultaneously additionally providing said preparation, belong to food and field of pharmaceutical technology.
Background technology
Radix Notoginseng has another name called Radix Notoginseng, the dry root of panax araliaceae plant Panaxnotoginseng (Burk.) F.H.Chen and rhizome, and main product is in Yunnan Wenshan Prefecture, therefore named mountain of papers Radix Notoginseng.Chinese crude drug Radix Notoginseng is using its root as medicinal effects, has dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain.
Sweet in the mouth, micro-hardship, temperature.Effect, dissipating blood stasis stops blooding, subduing swelling and relieving pain.Cure mainly for spitting blood, spit blood, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling.
A large amount of medical researches prove, Radix Notoginseng can be used for treating the various inside and outside hemorrhages such as traumatic hemorrhage, blood stasis, gastrorrhagia, hematuria；Expansion blood vessel, thrombus, improves microcirculation, the cardiovascular and cerebrovascular disease such as prevention and treatment hyperlipidemia, cholesterol increase, coronary heart diseases and angina pectoris, apoplexy sequela；The hepatopathy such as fatty liver, hepatic fibrosis and lose blood, body deficiency syndrome that puerperal, the reason such as prolonged illness cause.Radix Notoginseng, to cardiovascular system, to body material's metabolism, nervous system, auxiliary are suppressed anticancer, the antioxidation whitening colour of skin, slow down aging and tonification many-sided pharmacological action such as strong, makes it prevent and treat multiple disease, health care aspect extensive use.
But owing to Radix Notoginseng is warm in nature, easily consumption impairment of body fluid liquid, causes the disease of the deficiency of YIN.Show as and after taking Radix Notoginseng, occur that thirsty, constipation, myasthenia of limbs, dysphoria with smothery sensation, evening take the side effect such as insomnia.
Summary of the invention
The present invention provides a kind of notoginseng preparations processed, the present invention can improve take produce after Radix Notoginseng thirsty, constipation, myasthenia of limbs, the aspect side effect such as dysphoria with smothery sensation, invigorating middle warmer invigorating the spleen and regulating the stomach can be increased, promote the production of body fluid effect of intestine moistening, Radix Notoginseng is made to alleviate the not raw hot dryness-fire of consumption wound of body fluid while dissipating blood stasis stops blooding, improve Radix Notoginseng bitterness mouthfeel simultaneously, make people be easier to take.
The preparation of a kind of pear rice water Mel Radix Notoginseng of the present invention, it is characterised in that be made up by ratio of weight and the number of copies of following medicine:
Radix Notoginseng 5～100, pear 5～60, rice water 5～100, Mel 5～60,.
The preparation method of a kind of pear rice water Mel Radix Notoginseng of the present invention, comprises the steps:
1) Radix Notoginseng is cleaned smashing for coarse granule shape；
2) choose the squeezing of fresh pear, filter, add 2～4 times of clear water and obtain snow pear juice；
3) choose rice clear water will boil 20～30 minutes, be filtrated to get rice water and cool standby；
4) choosing Mel and add heating in pot, the goods that refining obtains to 105～110 DEG C, refined honey water content is more than 30%, and color and luster is without significant change, and slightly sticking refined honey is standby；
5) by step 2), 3), 4) to obtain pear rice water Mel standby for mix homogeneously；
6) the Radix Notoginseng granule after smashing being put into temperature in pear rice water Mel prepared by step 4) and control 10～20 DEG C of leaching systems 2～48 hours, period stirred 1 time every 6 hours so that it is is evenly distributed, soaks into Radix Notoginseng granule and fully absorb pear rice water Mel；
7 by leaching system after notoginseng drying to water content less than 15%, beat powder and get final product.
In above-mentioned any technical scheme, Radix Notoginseng raw material is 5～100 weight portions, it is preferable that 20～100 weight portions, further preferably 30～70 weight portion, more preferably 40～70 weight portion；Pear is 5～60 weight portions, it is preferable that 1～40 weight portion, further preferably 5～20 weight portion, more preferably 10～20 weight portion；Rice water is 5～100 weight portions, it is preferable that 5～80 weight portions, further preferably 40～80 weight portion, more preferably 50～70 weight portion；Refined honey is 5～60 weight portions, it is preferable that 1～40 weight portion, further preferably 5～20 weight portion, more preferably 10～20 weight portion.
The preparation method that the preparation method of the present invention may be used without the conventional formulation of medicine and pharmacology.
[function cures mainly] dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting blood, spit blood, epistaxis, to have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling, with deficiency of YIN symptom.
[usage and dosage] 3～9g；Swallow, a 1～3g.
[attention] anemia of pregnant woman is cautious use of.
The pharmacological effect side of the present invention solves as follows:
Pear
Nature and flavor acid sweet, micro-, cold；Attach to the lung and stomach meridians.Have and moisturize, promote the production of body fluid, heat clearing away effect, it is usually used in hyperactivity of fire caused by deficiency of YIN, dryness-heat impairing the lung, the auxiliary treatment that Tianjin wound is thirsty.Recording according to Compendium of Material Medica, " pears person, also, its property is descending fluently for profit." there is the effect of lung moistening clearing away dryness, promoting the production of body fluid to quench thirst, nourishing blood and promoting granulation.The traditional Chinese medical science thinks the lung and the large intestine being interior-exteriorly related, therefore has effect of moistening dryness for relaxing bowels while moisturizing lung heat clearing, and the throat therefore deficiency of YIN occurred is dry, thirsty, dryness of the intestine dry stool all has good effect.
Radix Notoginseng
Nature and flavor hardship sweet, micro-, temperature, return through returning liver, stomach warp.There is dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain.Cure mainly spitting of blood, spit blood, epistaxis, to have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling down swells and ache.Just it is acknowledged as since ancient times and there is significant blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain effect, there is the good reputation of " Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) ", " southern part of the country SHENCAO ".Cure mainly spitting of blood, spit blood, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling.
Rice water
Rice water nature and flavor are sweet flat, have QI invigorating, yin nourishing, the function moisturized, containing inorganic salts such as substantial amounts of nicotinic acid, vitamin B1, B2 and ferrophosphorus in rice water, also have the nutrients such as certain carbohydrate and fat.
Mel
Performance: sweet in the mouth, flat；Return taste, lung and large intestine channel.Function invigorating middle warmer, cough-relieving, moisturize, removing toxic substances.For the processing aids of invigorating the spleen and replenishing QI medicine, in order to potentiation, moisturize and correct mouthfeel.Such as Radix Ginseng (processed with honey), the processed with honey Radix Stemonae, Radix Asteris (processed with honey), processed with honey Flos Farfarae, processed with honey Folium Mori, processed with honey Cortex Mori, processed with honey Fructus Schisandrae Chinensis, Radix Glycyrrhizae (processed with honey) etc..
The present invention is based on theory of Chinese medical science basis, utilizes said medicine compatibility, makes Radix Notoginseng and pear rice water Mel mutual restraint between two drugs prove effective, utilizes the cool in nature of pear rice water Mel, the flat dry property of warm to reduce Radix Notoginseng of sweet in the mouth, improves the side effect such as thirsty, constipation, heating, insomnia.The nourshing Yin and drynsessmoistening prescription effect utilizing pear rice water Mel makes Radix Notoginseng not consume impairment of body fluid liquid while dissipating blood stasis stops blooding, not raw hot dryness-fire；Improve again Radix Notoginseng bitterness mouthfeel makes people be easier to take simultaneously.
Effectiveness for proving this invention has carried out pharmacological evaluation from pharmacodynamics aspect, is reported as follows:
Primary Radix Notoginseng powder can substantially increase mice autonomic activities number of times, hence it is evident that increases mice amount of drinking water and urine volume, and mice expression can be made irritated, movable increase；Hydrouria, darkens, and feces gets rid of minimizing, and shape is hard；The sleep of threshold dose pentobarbital sodium is had synergism, Sleep latency can be obviously prolonged, and curtail sleep；
Conclusion: primary Radix Notoginseng powder continuous oral 1 month, can make animal the side effect such as thirsty, constipation, insomnia occur.The continuous oral present invention 1 month, has no obvious animal and the side effect such as thirsty, dysphoria with smothery sensation, constipation, insomnia occurs.
The positive effect of the present invention is further illustrated below in conjunction with clinic:
One, diagnostic criteria:
Diagnosing according to " Diagnostics of Chinese Medicine ", various internal medicine are hemorrhage, traumatic hemorrhage, and various blood stasis cause pain, chest and abdomen twinge, and tumbling and swelling, simultaneously with deficiency of YIN person.
Two, inclusive criteria:
The above-mentioned standard of all genus all can include clinic in.Three, using method:
In composition of prescription, compatibility uses or folk prescription use.Four, curative effect judging standard:
Compare the side effect such as thirsty, constipation, myasthenia of limbs, insomnia all do not occur with primary Radix Notoginseng after the treatment of the application of the invention Radix Notoginseng.
The positive effect of the present invention is in that: the present invention is based on theory of Chinese medical science basis, utilize said medicine compatibility, Radix Notoginseng and pear rice water Mel mutual restraint between two drugs is made to prove effective, pear rice water Mel has effect of enriching yin boost qi, promoting the production of body fluid to quench thirst, moistening dryness for relaxing bowels relieving restlessness, the dry property of warm of Radix Notoginseng can be reduced, improve the side effect such as thirsty, constipation, heating, insomnia, make Radix Notoginseng not consume impairment of body fluid liquid while dissipating blood stasis stops blooding, raw hot dryness-fire；There is effect of enriching yin boost qi simultaneously, and Radix Notoginseng bitterness mouthfeel can be improved again make people be easier to take.
Detailed description of the invention
Embodiments below and case application, be only for clearly demonstrating example of the present invention, and be not limitation of the invention.For those of ordinary skill in the field, other multi-form change or variations can also be made on the basis of the above description.And the apparent change thus amplified out or variation are still among protection scope of the present invention.
Embodiment 1:
1, take 50g pseudo-ginseng, the removal of impurity, smash as coarse powder, through dry 1 hour of low temperature 30 DEG C, be dried to water content 20%；
2, taking the squeezing of 10g pear, filter, it is standby that addition 20g clear water obtains snow pear juice；
3, choose 50g rice addition 300g clear water to boil 20 minutes, filter and obtain rice water；
4, take 10g Mel temperature 110 DEG C refine 4 minutes refined honey water standby；
5, by step 2, that 3,4 mix homogeneously obtain pear rice water Mel is standby；
6, being placed in step 5 pear rice water Mel by the Radix Notoginseng raw material that step 1 is dry and stir soak system 8 hours constant temperature 20 DEG C, period stirred 1 time every 4 hours so that it is is evenly distributed, soaks into Radix Notoginseng and fully absorb pear rice water Mel；
7, step 6 is processed the Radix Notoginseng obtained and is placed in low-temperature vacuum drying case, dry 3 hours through low temperature 30 DEG C, be dried to water content 15%,
8, smash as impalpable powder and get final product.
Embodiment 2:
1, take 300g pseudo-ginseng, the removal of impurity, smash as coarse powder, through dry 1 hour of low temperature 30 DEG C, be dried to water content 20%；
2, taking the squeezing of 100g pear, filter, it is standby that addition 200g clear water obtains snow pear juice；
3, choose 150g rice to add 800g clear water and boil 25 minutes, filter and rice water；
4, take 200g Mel temperature 110 DEG C refine 10 minutes refined honey water standby；
5, by step 2, that 3,4 mix homogeneously obtain pear rice water Mel is standby；
6, being placed in step 5 pear rice water Mel by the Radix Notoginseng raw material that step 1 is dry and stir soak system 12 hours constant temperature 15 DEG C, period stirred 1 time every 4 hours so that it is is evenly distributed, soaks into Radix Notoginseng and fully absorb pear rice water Mel；
7, step 6 is processed the Radix Notoginseng obtained and be placed in low-temperature vacuum drying case, dry 5 hours through low temperature 23 DEG C, be dried to water content 13%；
8, smash as impalpable powder and get final product.
Embodiment 3:
1, take 100g pseudo-ginseng, the removal of impurity, smash as coarse powder, through dry 1 hour of low temperature 28 DEG C, be dried to water content 20%；
2, taking the squeezing of 80g pear, filter, it is standby that addition 200g clear water obtains snow pear juice；
3, choose 200g rice to add 700g clear water and boil 22 minutes, filter and rice water；
4, take 200g Mel temperature 110 DEG C refine 10 minutes refined honey water standby；
5, by step 2, that 3,4 mix homogeneously obtain pear rice water Mel is standby；
6, being placed in pear rice water Mel by the Radix Notoginseng raw material that step 1 is dry and stir soak system 8 hours constant temperature 18 DEG C, period stirred 1 time every 4 hours so that it is is evenly distributed, soaks into Radix Notoginseng and fully absorb pear rice water Mel；
7, step 6 is processed the Radix Notoginseng obtained and be placed in low-temperature vacuum drying case, dry 2 hours through low temperature 25 DEG C, be dried to water content 14%；
8, smash as impalpable powder and get final product.
The therapeutic effect of medicine of the present invention is further demonstrated that by following model case:
1, Lee, man 47 years old, diagnosis: upper gastrointestinal hemorrhage, hematemesis, black of defecating, gastric ulcer.
Treatment: every day 3 times, a 3g took the hemorrhage minimizing after 1 week of primary Radix Notoginseng powder, hematemesis stops, but causes blood deficiency owing to losing blood, and dysphoria with smothery sensation, thirsty, constipation symptom occurs.
Effect: the rear Radix Notoginseng powder using the embodiment of the present invention 1 preparation, often takes 3 grams, improves the symptom of dysphoria with smothery sensation, thirsty, constipation, do not occur any side effect yet, and disease is fully recovered after taking 30 days continuously after using pear rice water Mel Radix Notoginseng powder of the present invention every day 3 instead.
2, Zhang, female, 42 years old, diagnosis: hysteromyoma, hemorrhage, lower abdomen pain.
Treatment: using Radix Notoginseng powder auxiliary treatment, take Radix Notoginseng powder 3g every day 3 times, after taking 1 week, bleeding alleviates.But occur in that the side effect that Radix Notoginseng causes: thirsty, constipation, slightly have a sleepless night.
Effect: subsequently primary Radix Notoginseng powder is used instead in the embodiment of the present invention pear rice water Mel Radix Notoginseng powder of 2 preparations, thirsty after taking, constipation, the disappearance of mild insomnia shape.After taking 1 month continuously, hemorrhage, pain symptom is wholly absent.
3, poplar, man, 50 years old tcm diagnosis: the tcm syndrome differentiation and treatment deficiency of YIN is had blood in stool.
Treatment: compatibility Radix Rehmanniae Preparata, Fructus Corni, Rhizoma dioscoreae, Poria, the Rhizoma Anemarrhenae.Radix Notoginseng powder is taken after mixing it with water, every day 3 times, each 3g, and after taking 5 days continuously, basic stopping is had blood in stool, but serious being hard and dry occurs, simultaneously with thirsty, and the side reaction such as dysphoria with smothery sensation, myasthenia of limbs.
Effect: after by primary Radix Notoginseng powder this with the pear rice water Mel Radix Notoginseng powder in embodiment of the present invention 3, dysphoria with smothery sensation, thirsty side reaction disappear, and defecation is normal, do not occur any side effect after taking 21 days continuously yet, and disease is fully recovered.
Claims (2)
1. the preparation of a rice-washed water processed with honey Radix Notoginseng, it is characterised in that be made up by ratio of weight and the number of copies of following medicine:
Radix Notoginseng 5～100, Mel 5～60, rice-washed water 5～100.
2. the preparation method of a kind of rice-washed water processed with honey Radix Notoginseng according to claim 1, comprises the steps:
1) Radix Notoginseng is cleaned smashing for coarse powder；
2) choosing Mel and add heating in pot, the goods that refining obtains to 105～110 DEG C, refined honey water content is more than 30%, and color and luster is without significant change, and slightly sticking refined honey is standby；
3) choose rice clear water and eluriate that to obtain the rice-washed water of white opacity standby；
4) by step 2) and 3) to obtain refined honey rice-washed water standby for mix homogeneously；
5) the Radix Notoginseng coarse powder after smashing being put into temperature in refined honey rice-washed water prepared by step 4) and control 5～25 DEG C of leaching systems 2～48 hours, period stirred 1 time every 6 hours so that it is is evenly distributed, soaks into Radix Notoginseng granule and fully absorb refined honey rice-washed water；
6) by the notoginseng drying after leaching system to water content less than 15%；
7) Radix Notoginseng step 6) dried is pulverized as impalpable powder and get final product.
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| CN201610145585.5A CN105769959A (en) | 2016-03-15 | 2016-03-15 | Panax notoginseng preparation prepared from snow pears, rice water and honey, and preparation method |
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| CN201610145585.5A CN105769959A (en) | 2016-03-15 | 2016-03-15 | Panax notoginseng preparation prepared from snow pears, rice water and honey, and preparation method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110141593A (en) * | 2019-05-28 | 2019-08-20 | 黄再强 | A kind of preparation method of fresh Radix Notoginseng honey piece |
-
2016
- 2016-03-15 CN CN201610145585.5A patent/CN105769959A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110141593A (en) * | 2019-05-28 | 2019-08-20 | 黄再强 | A kind of preparation method of fresh Radix Notoginseng honey piece |
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