CN102961540A - Medicine for treating coronary heart disease and preparation method for same - Google Patents

Medicine for treating coronary heart disease and preparation method for same Download PDF

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Publication number
CN102961540A
CN102961540A CN2012104974901A CN201210497490A CN102961540A CN 102961540 A CN102961540 A CN 102961540A CN 2012104974901 A CN2012104974901 A CN 2012104974901A CN 201210497490 A CN201210497490 A CN 201210497490A CN 102961540 A CN102961540 A CN 102961540A
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China
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medicine
parts
heart disease
coronary heart
treatment
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CN2012104974901A
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Chinese (zh)
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闫位国
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Guangxi Dongxing City Innovation Characteristic Medical Science & Technology Development Co Ltd
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Guangxi Dongxing City Innovation Characteristic Medical Science & Technology Development Co Ltd
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Priority to CN2012104974901A priority Critical patent/CN102961540A/en
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Abstract

The invention provides a medicine for treating coronary heart disease and a preparation method for the same. The medicine is prepared into different preparations as needed by crushing eight traditional Chinese medicines of raw arisaema consanguineum schott, raw pinellia ternate, radix sophorae flavescentis, fried jujube kernel, radix aconiti carmichaeli, pseudo-ginseng, borneol and coptis chinensis into a fine powder according to a certain proportioning ratio. The medicine provided by the invention is prepared by taking the traditional Chinese medicine theories of China as basis, combining years of clinical practice, screening pure traditional Chinese medicines with the functions of activating blood and dispersing stagnation, as well as promoting coronary circulation and relieving pain from the treasure house of Chinese medicines, as well as is capable of effectively eliminating the diseases of oppression, ischemia and palpitation caused by the unsmooth blood flow of people with coronary heart disease. The medicine is moderate in properties, free from recurrence after medicine withdrawal, short in treatment course, fast to become effective, free of toxic or side effect, safe and reliable, and simple in production method, as well as is the first-choice good medicine for all people with coronary heart disease.

Description

A kind of medicine for the treatment of coronary heart disease and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of medicine for the treatment of coronary heart disease and preparation method thereof.
Background technology
Coronary heart disease is the abbreviation of coronary heart disease, it is a kind of because coronary atherosclerosis or vasospasm is narrow or stop up, the coronary circulation obstacle occurs, cause myocardial oxygen to and demand between unbalance and cause myocardial ischemia or downright bad a kind of heart disease, also be called ischemic heart desease.The main cause that causes primary disease is the improper and body deficiency due to old age of chronic dietary, inward invasion of pathogenic cold, disorder of emotion, mostly is immediate cause or inducement.Overweight muscle power or mental work on the basis of the motive and deficiency of heart-YANG, also can further consume sad gas, all can bring out or increase the weight of primary disease.Bend over the desk for a long time, like quiet few moving, can make dysfunction of the spleen in transportation, grow turbid expectorant, or breast sun mistake exhibition, QI-blood circulation is not smooth, all can encourage primary disease.The primary disease basic pathogenesis is blockage of the cardiac vessels, and stagnation of QI and blood may bring about pain under the effect of this multi-pathogenesis, can cause internal organs negative and positive of qi and blood imbalance, produces that expectorant is turbid, the stagnation of QI, blood stasis, thus numbness resistance heart arteries and veins and produce pained all diseases.Cardinal symptom is the squeezing sense of sudden shirtfront or pain, or there is paroxysmal pain at left breastbone rear portion, also can involve the positions such as most of pareordia.Pale complexion during outbreak, expression anxiety or agitation, palpitation and uneasiness, have palpitation, breathe hard, si dol urg can accompany and see cold sweat, often can cause sudden death.Because Incidence of CHD is high, mortality rate is high, the healthy of the mankind in serious harm, b referred to as " human the first killer ".
The medicament categories for the treatment of coronary heart disease is many, and great majority are western medicine, cure the symptoms, not the disease.Its treatment approach improves myocardial oxygen delivery and reduces myocardial oxygen consumption, thereby alleviate state of an illness symptom mainly with the medicine that adopts coronary dilating and decreased heart rate.Facts have proved, though this class medicine can be alleviated disease to a certain extent, exist all the time impairment of YIN, consumption gas, difficult Da Zhiben is sorry.Normally better during medication, in case the original state of an illness is just got back to again in drug withdrawal, if inappropriate medication also may be failed to respond to any medical treatment even increased the weight of disease.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of instant effect, medicine of the treatment coronary heart disease that therapeutic effect is good and preparation method thereof.
Technical scheme provided by the invention is a kind of medicine for the treatment of coronary heart disease, and it is made by the raw material of following weight portion: 30~60 parts of Rhizoma Arisaematis, 30~60 parts of Rhizoma Pinelliae, 30~60 parts of Radix Sophorae Flavescentiss, 30~60 parts of Semen Ziziphi Spinosae (parched)s, 30~60 parts of Radix Aconiti Lateralis Preparatas, 30~60 parts in Radix Notoginseng, 3~6 parts of Borneolum Syntheticums, 30~60 parts of Rhizoma Coptidis.
Preferred weight part of above-mentioned raw materials is: 45 parts of Rhizoma Arisaematis, 45 parts of Rhizoma Pinelliae, 50 parts of Radix Sophorae Flavescentiss, 50 parts of Semen Ziziphi Spinosae (parched)s, 50 parts of Radix Aconiti Lateralis Preparatas, 45 parts in Radix Notoginseng, 5 parts, 40 parts of Borneolum Syntheticums.
The dosage form of said medicine can be medically acceptable any dosage form, is specially pill or capsule.
The present invention also provides the preparation method of the medicine of above-mentioned treatment coronary heart disease, may further comprise the steps:
1) take by weighing Rhizoma Arisaematis, Rhizoma Pinelliae, Radix Sophorae Flavescentis, Semen Ziziphi Spinosae (parched), Radix Aconiti Lateralis Preparata, Radix Notoginseng, Borneolum Syntheticum, the Rhizoma Coptidis of formula ratio, be ground into fine powder, for subsequent use;
2) with above-mentioned fine powder mixing, make on demand different preparations.
The step 1 of above-mentioned preparation method) in, the granularity of fine powder is 100~300 orders.
The step 2 of above-mentioned preparation method) in, the dosage form of described preparation is pill or capsule.
The instructions of taking of medicine of the present invention is: take every day, takes minutes for 2~3 times, and each 0.6~1.2g takes with cold boiled water, and after meal or to take effect half an hour ante cibum better, 1 month was 1 course for the treatment of.
The mechanism of each raw medicinal material is as follows in the medicine of the present invention:
Rhizoma Arisaematis, drying dampness to eliminate phlegm is expellingged wind and relieving convulsion, mass dissipating and swelling eliminating; Rhizoma Pinelliae, acrid in the mouth, warm in nature, enter lung, spleen, stomach three warps, reducing swelling and alleviating pain; Radix Sophorae Flavescentis, bitter in the mouth, cold in nature enters liver, kidney, large intestine, small intestine meridian, bladder, heart channel, heat clearing and damp drying, parasite killing, diuresis; Semen Ziziphi Spinosae (parched), sweet in the mouth, acid, property is flat, enters heart channel, spleen channel, Liver Channel, gallbladder meridian, mind tranquilizing and the heart calming, nourishing the liver, arresting sweating; Radix Aconiti Lateralis Preparata, acrid in the mouth, sweet, extremely hot in nature, GUIXIN, kidney, spleen channel, recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, by wind-cold damp pathogen; Radix Notoginseng, warm in nature, sweet in the mouth, little hardship, nontoxic, return Liver Channel, stomach warp, heart channel, lung meridian, large intestine channel, hemostasis, loose blood, analgesic therapy.Borneolum Syntheticum, acrid in the mouth, hardship are slightly cold, and enter lung, liver two warps, and logical all keys, loose stagnated fire, removing nebula make eye bright, reducing swelling and alleviating pain; Rhizoma Coptidis, bitter in the mouth, cold in nature, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication.
Medicine of the present invention has the chest stuffiness relieving of regulating the flow of vital energy, changes the effect of turbid resolving depression, eliminating blood stasis and smoothing collaterals, effectively blood fat reducing anticoagulant, dilution thickness blood, thrombus, simultaneously can improve vascular endothelial function, remove vasospasm, can obviously treat the cardiopalmus ischemia, arrhythmia, coronary heart disease, the symptoms such as cardiopalmus infraction, alleviate various types of tachycardias, palpitation and short breath, uncomfortable in chest, shortness of breath and palpitation, the symptom such as weak are recovered function of nervous system, and can be prevented the generation of the cardiovascular and cerebrovascular disease vulnerable crowd cardiovascular and cerebrovascular disease such as hyperlipidemia, hypertension, diabetes.The present invention is pure Chinese medicinal preparation, and the gentle easily clothes of the property of medicine do not rebound after the drug withdrawal, short treating period, and instant effect, safe without toxic side effect, and also raw material sources are abundant, preparation method is simple, with low cost, are the first-selected good medicine of vast patients with coronary heart disease.
The specific embodiment
The invention will be further described with specific embodiment for the below, but be not limited to these embodiment.
Embodiment 1
1) proportioning by embodiment 1 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) each raw material select materials clean, the oven dry, grind to form 100 order fine powders, for subsequent use;
3) with the medicated powder disinfection, incapsulate, every capsules contains medicated powder 0.3g, and one day 2~3 times, each 2~3, cold boiled water takes, and one month is a course for the treatment of.
Embodiment 2
1) proportioning by embodiment 2 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) each raw material select materials clean, the oven dry, grind to form 300 order fine powders, for subsequent use;
3) medicated powder is mixed with conventional excipients, make pill, every heavy 0.4g of pill, one day 2~3 times, each 2~3, cold boiled water takes, and one month is a course for the treatment of.
Embodiment 3
1) proportioning by embodiment 3 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) each raw material select materials clean, the oven dry, grind to form 150 order fine powders, for subsequent use;
3) with the medicated powder disinfection, incapsulate, every capsules contains medicated powder 0.3g, and one day 2~3 times, each 2~3, cold boiled water takes, and one month is a course for the treatment of.
Embodiment 4
1) proportioning by embodiment 4 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) each raw material select materials clean, the oven dry, grind to form 200 order fine powders, for subsequent use;
3) medicated powder is mixed with conventional excipients, make pill, every heavy 0.4g of pill, one day 2~3 times, each 2~3, cold boiled water takes, and one month is a course for the treatment of.
Table 1
Raw material (g) Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
Rhizoma Arisaematis ?30 ?50 ?45 ?30
Rhizoma Pinelliae ?30 ?55 ?45 ?60
Radix Sophorae Flavescentis ?30 ?59 ?50 ?30
Semen Ziziphi Spinosae (parched) ?30 ?59 ?50 ?60
Radix Aconiti Lateralis Preparata ?30 ?57 ?50 ?30
Radix Notoginseng ?30 ?58 ?45 ?60
Borneolum Syntheticum ?3 ?6 ?5 ?3
Rhizoma Coptidis ?30 ?55 ?40 ?60
Use and the therapeutic effect of medicine of the present invention are described below in conjunction with concrete case.
Case 1: Tao Sutian, man, 60 years old, because suffering from hypertension 10 years, getting better through the multi-treatment end turns, headache, dizziness, left breast paroxysmal pain, day increases the weight of then, in the dizzy headache of in October, 2009 excuse, palpitating speed, moving then increase the weight of, be hypertension, hyperlipidemia, hyperglycemia, coronary heart disease through hospital diagnosis, take the Drug therapy 60 days of the embodiment of the invention 1 on October 5th, 2009, transference cure is followed up a case by regular visits to and was had no recurrence in 2 years.
Case 2: Li Shizhen, woman, 40 years old, in in May, 2008 because of palpitating speed, dizziness, the headache, there is twinge in the left side during pareordia, out of breath the increasing the weight of that walk, and lower limb are ice-cold, left side blood pressure 160~100 millimetress of mercury, blood pressure 170~100 millimetress of mercury in right side are 2 phase coronary heart disease of hypertension through hospital diagnosis, in August, 2008 with the medicine of the embodiment of the invention 2 50 days, transference cure is followed up a case by regular visits to and was had no recurrence in 2 years.
Case 3: Xu Guiying, the woman, 60 years old, in June, 2008, the dizzy headache of excuse has radiated pain during left breast shoulder, and was out of breath, the slight edema of two lower limb, blood pressure left side 180~110 millis become mercury column, and right side 170~100 millimetress of mercury are with uncomfortable in chest.In June 21 in 2008 the Nikkei hospital diagnosis be 2 phase hypertension, coronary heart disease.Take the medicine 48 days of the embodiment of the invention 3 on July 21st, 2008, transference cure is followed up a case by regular visits to and was had no recurrence in 2 years.
Case 4: Tian Qingbo, the man, 58 years old, paroxysmal pain is for many years in the heart for patient companion uncomfortable in chest, long-term taking Western medicine symptom can not be alleviated, in March, 2010 occur that pain increases the weight of, cardiopalmus gas is few, fatigue and weakness, moving symptom of then panting, check that electrocardiogram finds coronary insufficiency, begin to take the medicine 3 months of the embodiment of the invention 4 on March 25th, 2010, the check electrocardiogram recovers normal.
Case 5: Liu Hansheng, the man, 62 years old, existing 5 years coronary heart disease medical histories were had palpitation easily when movable, are felt oppressed, breathing heavily, and can't fall asleep night, and after the paroxysm perspire in the whole body, do not feel like a meal lip pastiness, black eye.Attempted for many years the distinct methods treatment, in case but just easily recurrence of drug withdrawal.The medicine that begins to take the embodiment of the invention 2 in August, 2011 is after 3 months, and above-mentioned symptom disappears, the recurrence of following up a case by regular visits to that so far there are no.
Case 6: Ou Yangchun, the woman, 57 years old, sensation of oppression over the chest with shortness of breath, the soreness of waist is weak, aversion to cold and cold limbs, cardiopalmus, pale complexion.Medical discovery of in October, 2009 pale tongue is dark, and deep-slow pulse is deficient and weak YANG QI.This day take the embodiment of the invention 2 described medicines after 15 days, symptom obviously alleviates, continue to take 15 days after, transference cure is followed up a case by regular visits to and is had no recurrence.
Case 7: blue preeminent, the man, 59 years old, suffered from cardiovascular disease 8 years, once be diagnosed as myocardial infarction, clinical manifestation is palpitation and short breath, uncomfortable in chest, in many ways sees a doctor and does not heal always.The medicine that begins to take the embodiment of the invention 3 in May, 2009 is after 1 month, clinical symptom disappearance, and after continuing to take 2 months, Electrocardioscopy is fully normal, and drug withdrawal follows the tracks of to follow up a case by regular visits to having no recurrence in 2 years.
Case 8: Wang Yuanjun, the man, 60 years old, the frequent cardiopalmus of patient is breathed hard, and was weak, insomnia, dreaminess, dizziness is in the medical red tongue of finding of in JIUYUE, 2008, light stripping no fur, indentations at the margin of the tongue, deep,thready and forceless pulse.This day begins to take the medicine of the embodiment of the invention 4 after 1 course for the treatment of, and symptom fades away, and for consolidating curative effect, after continuing to take 1 month, symptom all disappears, and drug withdrawal is followed up a case by regular visits to and had no recurrence in 2 years.

Claims (6)

1. medicine for the treatment of coronary heart disease, it is characterized in that: it is made by the raw material of following weight portion: 30~60 parts of Rhizoma Arisaematis, 30~60 parts of Rhizoma Pinelliae, 30~60 parts of Radix Sophorae Flavescentiss, 30~60 parts of Semen Ziziphi Spinosae (parched)s, 30~60 parts of Radix Aconiti Lateralis Preparatas, 30~60 parts in Radix Notoginseng, 3~6 parts of Borneolum Syntheticums, 30~60 parts of Rhizoma Coptidis.
2. the medicine for the treatment of coronary heart disease according to claim 1, it is characterized in that: the weight portion of each raw material is: 45 parts of Rhizoma Arisaematis, 45 parts of Rhizoma Pinelliae, 50 parts of Radix Sophorae Flavescentiss, 50 parts of Semen Ziziphi Spinosae (parched)s, 50 parts of Radix Aconiti Lateralis Preparatas, 45 parts in Radix Notoginseng, 5 parts of Borneolum Syntheticums, 40 parts of Rhizoma Coptidis.
3. the medicine for the treatment of coronary heart disease according to claim 1, it is characterized in that: the dosage form of this medicine is pill or capsule.
4. the preparation method of the medicine for the treatment of coronary heart disease claimed in claim 1 is characterized in that: may further comprise the steps:
1) take by weighing Rhizoma Arisaematis, Rhizoma Pinelliae, Radix Sophorae Flavescentis, Semen Ziziphi Spinosae (parched), Radix Aconiti Lateralis Preparata, Radix Notoginseng, Borneolum Syntheticum, the Rhizoma Coptidis of formula ratio, be ground into fine powder, for subsequent use;
2) with above-mentioned fine powder mixing, make on demand different preparations.
5. the process for preparing medicine for the treatment of coronary heart disease according to claim 4 is characterized in that: step 1) in, the granularity of described fine powder is 100~300 orders.
6. the process for preparing medicine for the treatment of coronary heart disease according to claim 4 is characterized in that: step 2) in, the dosage form of described preparation is pill or capsule.
CN2012104974901A 2012-11-29 2012-11-29 Medicine for treating coronary heart disease and preparation method for same Pending CN102961540A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105232677A (en) * 2015-10-10 2016-01-13 临沂草之美医药科技有限公司 Traditional Chinese medicine composition for treating myocardial infarction and preparation method of traditional Chinese medicine composition
CN113413412A (en) * 2021-05-31 2021-09-21 广东医科大学顺德妇女儿童医院(佛山市顺德区妇幼保健院) A composition containing oxymatrine and its application in preparing medicine for treating heart disease

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105232677A (en) * 2015-10-10 2016-01-13 临沂草之美医药科技有限公司 Traditional Chinese medicine composition for treating myocardial infarction and preparation method of traditional Chinese medicine composition
CN113413412A (en) * 2021-05-31 2021-09-21 广东医科大学顺德妇女儿童医院(佛山市顺德区妇幼保健院) A composition containing oxymatrine and its application in preparing medicine for treating heart disease

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Application publication date: 20130313