CN102666545B - 作为jak抑制剂的杂环吡唑并嘧啶类似物 - Google Patents

作为jak抑制剂的杂环吡唑并嘧啶类似物 Download PDF

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Publication number
CN102666545B
CN102666545B CN201080058290.5A CN201080058290A CN102666545B CN 102666545 B CN102666545 B CN 102666545B CN 201080058290 A CN201080058290 A CN 201080058290A CN 102666545 B CN102666545 B CN 102666545B
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pyrazolo
methyl
pyrazol
pyrimidin
amine
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CN102666545A (zh
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N·拉姆斯登
R·J·哈里森
S·奥克森福德
K·贝尔
N·皮顿
C·达戈斯廷
C·布萨尔
A·拉特克利夫
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Cellzome Ltd
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Cellzome Ltd
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Gastroenterology & Hepatology (AREA)
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  • Gynecology & Obstetrics (AREA)
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CN201080058290.5A 2009-10-20 2010-10-19 作为jak抑制剂的杂环吡唑并嘧啶类似物 Expired - Fee Related CN102666545B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP09173535.7 2009-10-20
EP09173535 2009-10-20
US37535810P 2010-08-20 2010-08-20
US61/375,358 2010-08-20
PCT/EP2010/065700 WO2011048082A1 (en) 2009-10-20 2010-10-19 Heterocyclyl pyrazolopyrimidine analogues as jak inhibitors

Publications (2)

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CN102666545A CN102666545A (zh) 2012-09-12
CN102666545B true CN102666545B (zh) 2016-04-06

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US (1) US9242987B2 (enExample)
EP (1) EP2491039A1 (enExample)
JP (1) JP5744887B2 (enExample)
KR (1) KR20120102601A (enExample)
CN (1) CN102666545B (enExample)
AR (1) AR078675A1 (enExample)
AU (1) AU2010309882B2 (enExample)
BR (1) BR112012009327A2 (enExample)
CA (1) CA2775009A1 (enExample)
EA (1) EA022120B1 (enExample)
IL (1) IL218751A0 (enExample)
MX (1) MX2012004020A (enExample)
NZ (1) NZ598907A (enExample)
TW (1) TW201125867A (enExample)
WO (1) WO2011048082A1 (enExample)

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