CN102657801A - Organic dairy cow breast disinfectant and preparation method thereof - Google Patents

Organic dairy cow breast disinfectant and preparation method thereof Download PDF

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Publication number
CN102657801A
CN102657801A CN2012101392345A CN201210139234A CN102657801A CN 102657801 A CN102657801 A CN 102657801A CN 2012101392345 A CN2012101392345 A CN 2012101392345A CN 201210139234 A CN201210139234 A CN 201210139234A CN 102657801 A CN102657801 A CN 102657801A
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cow breast
disinfectant solution
disinfectant
concentrating agents
organic type
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Chinese (zh)
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张翊
郝建
梁琥琪
张晓亮
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SHANGHAI YONGXIANG BIOTECHNOLOGY CO Ltd
University of Shanghai for Science and Technology
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SHANGHAI YONGXIANG BIOTECHNOLOGY CO Ltd
University of Shanghai for Science and Technology
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Priority to CN2012101392345A priority Critical patent/CN102657801A/en
Publication of CN102657801A publication Critical patent/CN102657801A/en
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Abstract

The invention relates to a dairy cow breast disinfectant, and belongs to the fields of biomedicine and medicaments for agriculture and livestock. The organic dairy cow breast disinfectant is characterized by comprising the following raw materials in percentage by mass according to the formula: 0.25 to 1 percent of 99 percent glycerol, 0.25 to 1 percent of synthetic Chinese medicinal herb concentrate, and the balance of deionized water. The Chinese medicinal herb concentrate is prepared from extracts of honeysuckle, indigowoad leaf, Chinese violet, muskroot-like semiaquilegia root, atractylodes rhizome, folium artemisiae argyi, phyllanthus ruinaria, dandelion, sophora flavescens, glabrous greenbrier rhizome, fructus cnidii, patrinia and groundsel by cleaning, extraction, re-extraction of primary residue, synthesis, decolorization and concentration, and the density of the concentrate is more than or equal to 1.04g/mm<3>. The disinfectant is used for diminishing dairy cow breast inflammation caused by invasion of multiple microbes such as candida albicans, escherichia coli, streptococcus, microsporum, salmonella and shigella and controlling invasion of pathogenic microbes on breasts and mammary glands of dairy cows.

Description

Organic type cow breast disinfectant solution and preparation method thereof
Technical field
The present invention relates to a kind of organic type cow breast disinfectant solution and preparation method thereof, belong to biological medicine and agriculture herding veterinary drug field.
Background technology
Before and after milch cow was milked, the breast area sterilization was a kind of means of total plate count amount in the domestic and international dairy husbandry control raw milk quality.
The industry present situation:
Like iodine class disinfectant, there is some weak point in existing traditional cow breast disinfectant in use, mainly shows: 1. zest is arranged; 2. volatile, easy residual.In view of these defectives that perplex all the time for many years, scholar, the research worker in this field have been done number of research projects.To the breast inflammation of milk cattle that the infringement that with Candida albicans, escherichia coli, streptococcus, sporidiole bacteria, Salmonella, shigella is master's multiple microorganism causes, the problem that emphasis solves is the invasion and attack of control source of disease microorganism to cow breast, mammary gland.
Find that after deliberation traditional Chinese herbal medicine Flos Lonicerae, Folium Isatidis, Herba Violae, Radix Semiaquilegiae, Rhizoma Atractylodis, Folium Artemisiae Argyi, Cacumen Securinegae Suffruticosae, Herba Taraxaci, Radix Sophorae Flavescentis, Rhizoma Smilacis Glabrae, Fructus Cnidii, Herba Patriniae, Herba Senecionis Scandentis pair and Candida albicans, escherichia coli, streptococcus, sporidiole bacteria, Salmonella, shigella are that main multiple microorganism has strongly, continues the inhibition killing action.
Summary of the invention
Defective to the prior art existence; The purpose of this invention is to provide a kind of organic type cow breast disinfectant solution and preparation method thereof; This disinfectant solution be have better bactericidal action, can effectively control the disinfectant solution of source of disease microorganism to the invasion and attack of cow breast, mammary gland; Both kept the good advantage of iodine class disinfectant solution bactericidal effect, overcome again iodine class disinfectant solution volatile, be prone to residual defective.
For achieving the above object, the technical scheme that the present invention adopts is:
Organic type cow breast disinfectant solution, the composition and the mass percent thereof of this disinfectant solution are following:
Glycerin (purity>99%) 0.25%~1%
Density>=1.04g/mm 3Synthetic Chinese medicine concentrating agents 0.25%~1%
The deionized water surplus
Described synthetic Chinese medicine concentrating agents is that the common process extraction of passing through of Flos Lonicerae 180g~220g, Folium Isatidis 180g~220g, Herba Violae 130g~170g, Radix Semiaquilegiae 180g~220g, Rhizoma Atractylodis 100g~140g, Folium Artemisiae Argyi 100g~140g, Cacumen Securinegae Suffruticosae 180g~220g, Herba Taraxaci 100g~140g, Radix Sophorae Flavescentis 230g~270g, Rhizoma Smilacis Glabrae 230g~270g, Fructus Cnidii 280g~320g, Herba Patriniae 130g~170g, Herba Senecionis Scandentis 180g~220g gets; Promptly extract again → synthesize → decolour → concentrate, finally obtain density>=1.04g/ mm through cleaning → extraction → female slag 3Concentrating agents.
The method for preparing of organic type cow breast disinfectant solution, described milk cow sterilizing liquid is water aqua type, its preparation method is following: at first by above-mentioned prescription weigh batching, make density>=1.04g/ mm 3The synthetic Chinese medicine concentrating agents; Get said synthetic Chinese medicine concentrating agents 2.5g~10g, add 2.5g~10g Chun Du>99% glycerin is blended into deionized water to 1000g after stirring, and promptly makes organic type cow breast disinfectant solution after stirring.
Than prior art, the advantage of milk cow sterilizing liquid of the present invention and effect can be concluded narration as follows:
1. product of the present invention is having tangible kill activity to Candida albicans, escherichia coli, streptococcus, sporidiole bacteria, Salmonella, shigella etc. less than 20s in the time.
2. zest is little, selects for use glycerin (content>99%) to cooperate, and has the effect of skin protection, skin moistening concurrently, prevents xerosis cutis, be full of cracks.
3. there is not anaphylaxis.
Description of drawings
Fig. 1 is the process chart of organic type cow breast disinfectant solution of the present invention.
The specific embodiment
Below in conjunction with accompanying drawing and specific embodiment embodiments of the invention are described in further detail.
As shown in Figure 1, used Chinese herbal medicine concentrating agents is to be prepared from through the conventional process of tradition in the present embodiment.Its preparation method is following:
Flos Lonicerae 200g, Folium Isatidis 200g, Herba Violae 150g, Radix Semiaquilegiae 200g, Rhizoma Atractylodis 120g, Folium Artemisiae Argyi 120g, Cacumen Securinegae Suffruticosae 200g, Herba Taraxaci 120g, Radix Sophorae Flavescentis 250g, Rhizoma Smilacis Glabrae 250g, Fructus Cnidii 300g, Herba Patriniae 150g, Herba Senecionis Scandentis 200g are extracted → synthesize → decolour → concentrate density again through cleaning → extraction → mother solution and arrive>=1.04g/ mm 3Get final product.Its concrete manufacturing process is: Flos Lonicerae, Folium Isatidis, Herba Violae, Radix Semiaquilegiae, Rhizoma Atractylodis, Folium Artemisiae Argyi, Cacumen Securinegae Suffruticosae, Herba Taraxaci, Radix Sophorae Flavescentis, Rhizoma Smilacis Glabrae, Fructus Cnidii, Herba Patriniae, the Herba Senecionis Scandentis that will clean the back drying add deionized water to not having about medicine 30mm; Be heated to 105 ℃ of insulations 10 minutes; After be cooled to 80 ℃ the insulation 20 minutes, after extract liquid.Female slag adds deionized water once more to not having about medicine 5mm, is heated to 105 ℃ of insulations 10 minutes, after be cooled to 80 ℃ of insulations 20 minutes, after extract liquid.Two liquid merge after decolouring is concentrated to>=1.04g/ mm 3Get final product.
Get said synthetic Chinese medicine concentrating agents 5g, add 5g purity 99% glycerin, be blended into deionized water to 1000g after stirring, promptly make organic type cow breast disinfectant solution after stirring.
This organic type cow breast disinfectant solution through Shanghai City milk measuring station testing result see table 1, table 2.
Table 1 organic type cow breast disinfectant solution laboratory sterilization effect
Figure 770687DEST_PATH_IMAGE001
Annotate: the ATP test bar that adopts Minnesota Mining and Manufacturing Company to produce carries out in solution, and recommended density is 0.25% and 0.5%.When free bacterium number shows effectively during greater than total bacteria count.
The on-the-spot clinical trial sterilization effect of table 2 organic type cow breast disinfectant solution
Figure 662136DEST_PATH_IMAGE001
Can find that from above two tables it is 0.25%~0.5% that laboratory is recommended the concentration of this disinfectant solution, and in the field trial 0.25% disinfectant solution concentration reality in the 30s to source of disease microorganism do not have obvious effect.It is thus clear that clinical source of disease microorganism is obstinate than the microorganism of laboratory source of disease.So the design of the content of the extracts of Chinese herbal medicine of product of the present invention is 0.5%.
Table 3 organic type cow breast disinfectant solution and traditional cow breast disinfectant compare
? Bactericidal effect Residual Stimulate Nursing role To environmental effect
Product of the present invention 5 seconds killing microorganisms Do not have Do not have Have Do not have
Reference product 5 seconds killing microorganisms Have Have Do not have Have

Claims (2)

1. organic type cow breast disinfectant solution is characterized in that, the composition and the mass percent thereof of this disinfectant solution are following:
Purity>99% glycerin 0.25%~1%
Density>=1.04g/mm 3Synthetic Chinese medicine concentrating agents 0.25%~1%
The deionized water surplus
Described synthetic Chinese medicine concentrating agents is that the common process extraction of passing through of Flos Lonicerae 180g~220g, Folium Isatidis 180g~220g, Herba Violae 130g~170g, Radix Semiaquilegiae 180g~220g, Rhizoma Atractylodis 100g~140g, Folium Artemisiae Argyi 100g~140g, Cacumen Securinegae Suffruticosae 180g~220g, Herba Taraxaci 100g~140g, Radix Sophorae Flavescentis 230g~270g, Rhizoma Smilacis Glabrae 230g~270g, Fructus Cnidii 280g~320g, Herba Patriniae 130g~170g, Herba Senecionis Scandentis 180g~220g gets; Promptly extract again → synthesize → decolour → concentrate, finally obtain density>=1.04g/ mm through cleaning → extraction → female slag 3Concentrating agents.
2. the method for preparing of organic type cow breast disinfectant solution; Be used to prepare organic type cow breast disinfectant solution as claimed in claim 1, it is characterized in that, described milk cow sterilizing liquid is water aqua type; Its preparation method is following: at first by above-mentioned prescription weigh batching, make density>=1.04g/ mm 3The synthetic Chinese medicine concentrating agents; Get said synthetic Chinese medicine concentrating agents 2.5g~10g, add 2.5g~10g Chun Du>99% glycerin is blended into deionized water to 1000g after stirring, and promptly makes organic type cow breast disinfectant solution after stirring.
CN2012101392345A 2012-05-08 2012-05-08 Organic dairy cow breast disinfectant and preparation method thereof Pending CN102657801A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103271102A (en) * 2013-05-31 2013-09-04 沁阳市崇义中天养殖场 Chinese herbal medicine environmentally-friendly sanitizer for dairy farm
CN106342962A (en) * 2016-08-28 2017-01-25 广西兴胜农牧有限公司 Method for disinfecting dairy farms
CN106342949A (en) * 2016-08-28 2017-01-25 广西兴胜农牧有限公司 Disinfectant for dairy farms and method for preparing the disinfectant
CN106342952A (en) * 2016-08-28 2017-01-25 广西兴胜农牧有限公司 Disinfectant for dairy farms
CN106417406A (en) * 2016-08-28 2017-02-22 广西兴胜农牧有限公司 Disinfectant for disinfecting dairy farm
CN106982742A (en) * 2017-02-24 2017-07-28 河南牧业经济学院 Milk cow production column bed filler, mattress and its application method
CN110038045A (en) * 2019-05-21 2019-07-23 郑州百瑞动物药业有限公司 A kind of mammilla of milk cattle disinfectant preparation and preparation method thereof

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RU2367433C1 (en) * 2008-03-07 2009-09-20 Закрытое акционерное общество научно-производственное предприятие "Агрофарм" (ЗАО НПП "Агрофарм") Preparation for mastitis treatment in lactating cows
CN101537104A (en) * 2009-05-07 2009-09-23 赵守财 Traditional Chinese medicinal composition for treating dairy cow mastitis, preparation method and applications thereof
CN101797329A (en) * 2010-04-01 2010-08-11 上海大学 Safety milk cow sterilizing nursing agent
CN102274142A (en) * 2011-07-19 2011-12-14 北京联合大学生物化学工程学院 Preparation method of compound Chinese medicine washing liquid

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Publication number Priority date Publication date Assignee Title
CN1334077A (en) * 2000-07-17 2002-02-06 尹庆文 Medicinal bath lotion
US20080153894A1 (en) * 2002-12-19 2008-06-26 Pharmacia Corporation Cyclooxygenase-2 inhibitor and antibacterial agent combination for intramammary treatment of mastitis
CN101041032A (en) * 2007-04-30 2007-09-26 周鑫 Bath lotion for preventing pruritus
RU2367433C1 (en) * 2008-03-07 2009-09-20 Закрытое акционерное общество научно-производственное предприятие "Агрофарм" (ЗАО НПП "Агрофарм") Preparation for mastitis treatment in lactating cows
CN101537104A (en) * 2009-05-07 2009-09-23 赵守财 Traditional Chinese medicinal composition for treating dairy cow mastitis, preparation method and applications thereof
CN101797329A (en) * 2010-04-01 2010-08-11 上海大学 Safety milk cow sterilizing nursing agent
CN102274142A (en) * 2011-07-19 2011-12-14 北京联合大学生物化学工程学院 Preparation method of compound Chinese medicine washing liquid

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103271102A (en) * 2013-05-31 2013-09-04 沁阳市崇义中天养殖场 Chinese herbal medicine environmentally-friendly sanitizer for dairy farm
CN103271102B (en) * 2013-05-31 2015-09-02 焦作市穆升牛业有限公司 Chinese herbal medicine environmentally-friesanitizer sanitizer for dairy farm
CN106342962A (en) * 2016-08-28 2017-01-25 广西兴胜农牧有限公司 Method for disinfecting dairy farms
CN106342949A (en) * 2016-08-28 2017-01-25 广西兴胜农牧有限公司 Disinfectant for dairy farms and method for preparing the disinfectant
CN106342952A (en) * 2016-08-28 2017-01-25 广西兴胜农牧有限公司 Disinfectant for dairy farms
CN106417406A (en) * 2016-08-28 2017-02-22 广西兴胜农牧有限公司 Disinfectant for disinfecting dairy farm
CN106982742A (en) * 2017-02-24 2017-07-28 河南牧业经济学院 Milk cow production column bed filler, mattress and its application method
CN110038045A (en) * 2019-05-21 2019-07-23 郑州百瑞动物药业有限公司 A kind of mammilla of milk cattle disinfectant preparation and preparation method thereof

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Application publication date: 20120912