CN104666635A - Externally-applied traditional Chinese medicine ointment for treating acute mastitis of dairy cow and preparation method of ointment - Google Patents

Externally-applied traditional Chinese medicine ointment for treating acute mastitis of dairy cow and preparation method of ointment Download PDF

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Publication number
CN104666635A
CN104666635A CN201310642446.XA CN201310642446A CN104666635A CN 104666635 A CN104666635 A CN 104666635A CN 201310642446 A CN201310642446 A CN 201310642446A CN 104666635 A CN104666635 A CN 104666635A
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China
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chinese medicine
cow
preparation
ointment
external application
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CN201310642446.XA
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陈庆忠
安同伟
李迎梅
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TIANJIN ZHONGAO FEED Co Ltd
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TIANJIN ZHONGAO FEED Co Ltd
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Abstract

The invention relates to externally-applied traditional Chinese medicine ointment for treating acute mastitis of a dairy cow and a preparation method of the ointment. The traditional Chinese medicine ointment is prepared by steps of grinding and crushing five raw materials including cordate houttuynia, herba violae, honeysuckle, myrrh and rhizoma corydalis and blending by using vinegar and honey. Lots of treatment tests prove that the traditional Chinese medicine ointment disclosed by the invention is particularly remarkable in treatment effect and free of any toxic and side effects.

Description

External application Chinese medicine unguentum for the treatment of acute mammitis of cow and preparation method thereof
Technical field
The invention belongs to field of veterinary, especially a kind of external application Chinese medicine unguentum for the treatment of acute mammitis of cow and preparation method thereof.
Background technology
Acute mastitis is that breast presents redness, burning pain is main symptom, and refuse a kind of frequently-occurring disease of young stock sucking or artificial suckling, show as mammary swelling more, milk is not smooth or obstructed, extrude a small amount of milk or the water sample milk that contain small pieces floccule, what have is mixed with bean curd scoriform thing, and oppressing newborn pond has crepitation, often with General Symptomies such as heatings.Multiplely to be born between female animal age of sucking in puerperal.Chinese veterinarian claims primary disease to be that milk is swollen, milk is yellow, acute mastitis.To this sick as treatment not in time or wrong treatment or curative effect not good, often cause breast suppurate or change into chronic inflammatory disease, cause eliminating of milch cow.In order to address this problem, we have explored the present invention on the basis of front this disease of human therapy.
Summary of the invention
The object of the present invention is to provide a kind of external application Chinese medicine unguentum for the treatment of acute mammitis of cow, this Chinese medicinal ointment heat-clearing and toxic substances removing, antimicrobial and anti-inflammation efficacy are strong, effectively fast can obtain prevention and therapy acute mammitis of cow.
Another object of the present invention is to provide a kind of preparation method for the treatment of the external application Chinese medicine unguentum of acute mammitis of cow.
The present invention is achieved by the following technical solutions:
Treat an external application Chinese medicine unguentum for acute mammitis of cow, component and the ratio of weight and number thereof of its Chinese medicinal ointment are respectively:
Treat a preparation method for the external application Chinese medicine unguentum of acute mammitis of cow, the step of its preparation method is as follows:
(1) take Myrrha and Rhizoma Corydalis respectively by weight ratio, add in grinder and carry out grinding 15-60 minute, medicamental pulverata A must be mixed, for subsequent use;
(2) take Herba Houttuyniae, Herba Violae and Flos Lonicerae respectively by weight ratio, pulverize, the concentration adding 15-45 times amount is 50%-95% alcoholic solution, be 40-60 DEG C in temperature and extract 30-65min, filter, concentrated after add equivalent volumes chloroform carry out remove impurity, obtain extract B, for subsequent use;
(3) weight ratio of getting 2-5 times amount is vinegar and the honey mixt of 5:1, and mediation step (1) gained mixing medicamental pulverata A and step (2) extract obtained B, must treat the external application Chinese medicine unguentum finished product of acute mammitis of cow.
Advantage of the present invention and beneficial effect are:
1, be used as medicine after the Myrrha in the present invention and Rhizoma Corydalis grinding, finer and smoother, drug effect utilizes fully, and nontoxic non-stimulated, and safety has no side effect.
2, the Herba Houttuyniae in the present invention, Herba Violae and Flos Lonicerae extract are concentrated to be used as medicine, and the good drug effect of its heat-clearing and toxic substances removing, inhibiting bacteria and diminishing inflammation, especially to the symptom such as redness, burning pain because of staphylococcus and the microbial serosity of hammer and Catarrhal acute mastitis.
Detailed description of the invention
The present invention is described in further detail by following examples.It should be noted that: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Herba Houttuyniae involved in the present invention, Herba Violae, Flos Lonicerae, Myrrha, Rhizoma Corydalis all commercially can be bought and obtain.
Embodiment 1
Treat an external application Chinese medicine unguentum for acute mammitis of cow, component and the weight thereof of its Chinese medicinal ointment are respectively: Herba Houttuyniae 5kg, Herba Violae 1kg, Flos Lonicerae 1kg, Myrrha 1kg, Rhizoma Corydalis 1kg.
Treat a preparation method for the external application Chinese medicine unguentum of acute mammitis of cow, the step of its preparation method is as follows:
(1) take Myrrha and Rhizoma Corydalis respectively by weight ratio, add in grinder and carry out grinding 15 minutes, medicamental pulverata A must be mixed, for subsequent use;
(2) take Herba Houttuyniae, Herba Violae and Flos Lonicerae respectively by weight ratio, pulverize, the concentration adding 15 times amount is 50% alcoholic solution, be 40 DEG C in temperature and extract 30min, filter, concentrated after add equivalent volumes chloroform carry out remove impurity, obtain extract B, for subsequent use;
(3) weight ratio of getting 2 times amount is vinegar and the honey mixt of 5:1, and mediation step (1) gained mixing medicamental pulverata A and step (2) extract obtained B, must treat the external application Chinese medicine unguentum finished product of acute mammitis of cow.
Embodiment 2
Treat an external application Chinese medicine unguentum for acute mammitis of cow, component and the weight thereof of its compositions are respectively: Herba Houttuyniae 50kg, Herba Violae 45kg, Flos Lonicerae 10kg, Myrrha 20kg, Rhizoma Corydalis 30kg.
Treat a preparation method for the external application Chinese medicine unguentum of acute mammitis of cow, the step of its preparation method is as follows:
(1) take Myrrha and Rhizoma Corydalis respectively by weight ratio, add in grinder and carry out grinding 60 minutes, medicamental pulverata A must be mixed, for subsequent use;
(2) take Herba Houttuyniae, Herba Violae and Flos Lonicerae respectively by weight ratio, pulverize, the concentration adding 45 times amount is 95% alcoholic solution, be 60 DEG C in temperature and extract 65min, filter, concentrated after add equivalent volumes chloroform carry out remove impurity, obtain extract B, for subsequent use;
(3) weight ratio of getting 5 times amount is vinegar and the honey mixt of 5:1, and mediation step (1) gained mixing medicamental pulverata A and step (2) extract obtained B, must treat the external application Chinese medicine unguentum finished product of acute mammitis of cow.
Embodiment 3
Treat an external application Chinese medicine unguentum for acute mammitis of cow, component and the weight thereof of its compositions are respectively: Herba Houttuyniae 20kg, Herba Violae 4kg, Flos Lonicerae 4kg, Myrrha 4kg, Rhizoma Corydalis 4kg.
Treat a preparation method for the external application Chinese medicine unguentum of acute mammitis of cow, the step of its preparation method is as follows:
(1) take Myrrha and Rhizoma Corydalis respectively by weight ratio, add in grinder and carry out grinding 40 minutes, medicamental pulverata A must be mixed, for subsequent use;
(2) take Herba Houttuyniae, Herba Violae and Flos Lonicerae respectively by weight ratio, pulverize, the concentration adding 30 times amount is 75% alcoholic solution, be 50 DEG C in temperature and extract 45min, filter, concentrated after add equivalent volumes chloroform carry out remove impurity, obtain extract B, for subsequent use;
(3) weight ratio of getting 4 times amount is vinegar and the honey mixt of 5:1, and mediation step (1) gained mixing medicamental pulverata A and step (2) extract obtained B, must treat the external application Chinese medicine unguentum finished product of acute mammitis of cow.
Usage and dosage of the present invention is: extrude and to suffer from cow breast after milk, clean breast, then dry with dry towel, the present invention be from top to bottom applied on breast, change dressings every day twice time, be used in conjunction 4 days with warm water.
Clinical practice
Test one
Within 2011, choose in the large-scale cattle farm of Shandong Zibo the milch cow that 45 are suffered from acute mastitis, under identical rearing conditions, stochastic averagina is divided into 5 groups, often organizes 9; Penicillin+streptomycin group is through papillary duct drug administration by injection, and 4% sodium hypochlorite is dipping 30 seconds/time, and twice daily, each group process is as following table.
Table 1 the present invention is to the therapeutic effect-Shandong of acute mammitis of cow
The sick cattle number of group Cure head number Effective number Clinical cure rate Effective percentage
High dose group 9 of the present invention 8 9 88.89% 100.00%
Dosage group 9 in the present invention 7 9 77.78% 100.00%
Low dose group 9 of the present invention 6 8 66.67% 88.89%
Penicillin+streptomycin group 9 6 7 66.67% 77.78%
4% sodium hypochlorite group 9 4 6 44.44% 66.67%
Result shows: the present invention has good curative effect to acute mammitis of cow, administration is after 4 days, the overwhelming majority suffers from red, swollen, the hot transference cure of cow breast, part partial gall alleviates, wherein high dose group of the present invention, cure rate reaches 88.89%, and effective percentage reaches 100.00%, apparently higher than penicillin+streptomycin group and 4% sodium hypochlorite group, two matched groups.
Test two
In November, 9 ~ 2012 in 2011, choose in the large-scale dairy cow farm in Suizhou, Hubei Province the milch cow that 50 are suffered from acute mastitis, under identical rearing conditions, stochastic averagina is divided into 5 groups, often organizes 10; Penicillin+streptomycin group is through papillary duct drug administration by injection, and 4% sodium hypochlorite is dipping 30 seconds/time, and twice daily, each group process is as following table.
Table 2 the present invention is to the therapeutic effect-Hubei of acute mammitis of cow
Group Size of animal Cure head number Effective number Cure rate Effective percentage
High dose group of the present invention 10 9 10 90.00% 100.00%
Dosage group in the present invention 10 7 9 70.00% 90.00%
Low dose group of the present invention 10 6 9 60.00% 90.00%
0.2% sodium hypochlorite group 10 5 6 50.00% 60.00%
Penicillin+streptomycin group 10 7 8 70.00% 80.00%
Result shows: the present invention is obvious to acute mammitis of cow curative effect, and administration is after 4 days, and high dose group cure rate of the present invention is higher than penicillin+streptomycin 20 percentage points, the overwhelming majority suffers from cattle acute mastitis transference cure, red and swollen block dissipates, and partial gall alleviates, and effective percentage is all more than 90%.

Claims (2)

1. treat an external application Chinese medicine unguentum for acute mammitis of cow, it is characterized in that: component and the ratio of weight and number thereof of this Chinese medicinal ointment are respectively:
2. a preparation method for the external application Chinese medicine unguentum for the treatment of acute mammitis of cow as claimed in claim 1, is characterized in that: the step of this preparation method is as follows:
(1) take Myrrha and Rhizoma Corydalis respectively by weight ratio, add in grinder and carry out grinding 15-60 minute, medicamental pulverata A must be mixed, for subsequent use;
(2) take Herba Houttuyniae, Herba Violae and Flos Lonicerae respectively by weight ratio, pulverize, the concentration adding 15-45 times amount is 50%-95% alcoholic solution, be 40-60 DEG C in temperature and extract 30-65min, filter, concentrated after add equivalent volumes chloroform carry out remove impurity, obtain extract B, for subsequent use;
(3) weight ratio of getting 2-5 times amount is vinegar and the honey mixt of 5:1, and mediation step (1) gained mixing medicamental pulverata A and step (2) extract obtained B, must treat the external application Chinese medicine unguentum finished product of acute mammitis of cow.
CN201310642446.XA 2013-12-03 2013-12-03 Externally-applied traditional Chinese medicine ointment for treating acute mastitis of dairy cow and preparation method of ointment Pending CN104666635A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017144925A1 (en) * 2016-02-24 2017-08-31 Gavranovic Dragan Topical composition for treatment and/or prophilaxis of mastitis and/or edema
CN109045219A (en) * 2018-10-26 2018-12-21 天水师范学院 It is a kind of for treating the careless compound external-use paste of red cyclopentadienyl of female rabbit mammitis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1660209A (en) * 2004-12-21 2005-08-31 江苏省农业科学院 Film coating agent for treating mastitis of milch cows and preparation methde

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1660209A (en) * 2004-12-21 2005-08-31 江苏省农业科学院 Film coating agent for treating mastitis of milch cows and preparation methde

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
张传美等: "九味中药及其复方对奶牛乳房炎病原菌的体外抑菌试验", 《动物医学进展》 *
梁崇杰等编著: "《畜禽常见病土法良方3000例》", 30 September 2006, 四川科学技术出版社 *
许振涛等: "奶牛乳房炎的综合防控", 《山东畜牧兽医》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017144925A1 (en) * 2016-02-24 2017-08-31 Gavranovic Dragan Topical composition for treatment and/or prophilaxis of mastitis and/or edema
CN109045219A (en) * 2018-10-26 2018-12-21 天水师范学院 It is a kind of for treating the careless compound external-use paste of red cyclopentadienyl of female rabbit mammitis
CN109045219B (en) * 2018-10-26 2021-05-11 天水师范学院 Compound herba Rabdosiae Glaucocalycis external ointment for treating female rabbit mastitis

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