CN102846795A - Chinese medicine composition for preventing and treating mastitis of dairy cattle and preparation method thereof - Google Patents

Chinese medicine composition for preventing and treating mastitis of dairy cattle and preparation method thereof Download PDF

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Publication number
CN102846795A
CN102846795A CN201210402202XA CN201210402202A CN102846795A CN 102846795 A CN102846795 A CN 102846795A CN 201210402202X A CN201210402202X A CN 201210402202XA CN 201210402202 A CN201210402202 A CN 201210402202A CN 102846795 A CN102846795 A CN 102846795A
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China
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chinese medicine
medicine composition
dairy cattle
cow
mastitis
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杨学云
魏玉荣
吴建勇
王登峰
李建军
徐猛
易忠
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VETERINARY RESEARCH INSTITUTE OF XINJIANG UYGUR AUTONOMOUS REGION ANIMAL SCIENCES ACADEMY
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VETERINARY RESEARCH INSTITUTE OF XINJIANG UYGUR AUTONOMOUS REGION ANIMAL SCIENCES ACADEMY
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Priority to CN201210402202XA priority Critical patent/CN102846795A/en
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Abstract

The invention relates to Chinese medicine composition for preventing and treating mastitis of dairy cattle and a preparation method thereof. The Chinese medicine composition comprises the following components: dandelion, selfheal spike, green tangerine peel and liquorice. The dandelion, the selfheal spike, the green tangerine peel and the liquorice are smashed and then uniformly mixed in proportion to obtain the Chinese medicine composition, the form of the Chinese medicine composition is powder. The Chinese medicine composition has the advantages of reasonable combination and preparation, simple manufacturing process, low cost, favorable taste, convenience in use, no medicine residue and no side effects. The Chinese medicine composition can be used for dairy cattle and pregnant cattle. The Chinese medicine composition provided by the invention can be used for effectively preventing and treating mastitis of dairy cattle, reducing the economic loss, and enhancing the economic benefits of the dairy cattle breading industry. The clinical tests prove that the effective rate of the Chinese medicine composition in firstly treating recessive mastitis of the dairy cattle reaches 100%, the effective rate of the Chinese medicine composition in the milk area is over 85%, and the effective rate of the Chinese medicine composition in treating clinical mastitis of the dairy cattle is over 85%. The Chinese medicine composition is suitable for preventing and treating mastitis of dairy cattle of individual farmers and scale dairy cattle fields.

Description

A kind of Chinese medicine composition of preventing and treating mammitis of cow and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition of preventing and treating mammitis of cow and preparation method thereof.
Background technology
Mammitis of cow is a kind of common, the multiple disease of milch cow, also is to have a strong impact on one of topmost disease of dairy aquaculture economic benefit.This disease not only affects milk yield, milk quality, and prolongs post-partum estrus and pregnant time, causes the Lactation of Dairy Cow defunctionalization when serious and is eliminated, and brings the tremendous economic loss to dairy.It is reported that the mammitis of cow sickness rate of the U.S. is 30%-70%, the average mastitis prevalence of Japan is 45.1%, and the mammitis of cow positive rate of China is 46.4%-85.7%.According to statistics, China's mammitis of cow sickness rate generally is higher than abroad, and every year is caused the loss of several hundred million units because of mastitis in the whole nation.
Mammitis of cow is a complex disease with numerous causes of disease, its morbidity main cause is: 1. cause pathogeny imcrobe infection: cause pathogeny imcrobe infection is the first cause that causes mammitis of cow, be divided into two classes by its spread path: a class is the contagious infection pathogenic microorganism, and another kind of is environment sexually transmitted disease (STD) pathogenic microorganism.The contagious infection pathogenic microorganism mainly contains staphylococcus aureus, streptococcus agalactiae, streptococcus dysgalactiae, mycoplasma etc.Environment sexually transmitted disease (STD) pathogenic microorganism is present in feces, bedding and padding or straw in a mattress, sewage, sports ground, mainly is escherichia coli, cow breast streptococcus, suppurative corynebacterium etc.When the body function descends or the nipple damage, invade breast so that breast barrier function reduces and cause infection.2. feeding and management factor: cowshed, milk place and milking routine disinfecting system are not strict, and the veterinary personnel of basic unit lack a sense of responsibility; Mechanical milking does not carry out in operation sequence, hand milking's operational approach is improper, mode that the person of milking is changed frequent or flip-flop is milked, the secondary infection disease is in time treatment, and is correct to the milch cow that arrives the dry milk phase, in time the factor such as dry milk all is to cause the common cause of mastitis.3. nutrition, environmental factors: the uneven or excessive sickness rate that also can increase mastitis of feed ingredient flip-flop, daily ration heterogeneity; High temperature, high humidity make milch cow be in the heat stress state season, and loss of appetite, body disease-resistant power weaken, and are the key factors that causes latent mammitis to occur.Cowshed is stuffy, untidy, and sports ground is put aside in a large number excrement, urine and sewage and caused the cattle body unclean; The sanitary condition of living environment is poor all to be the key factor of bringing out latent mammitis.
Mainly be to strengthen feeding and management, maintenance environmental health, standard milking routine etc. to the prevention method of mastitis at present.Carry out in addition the injection of mastitis vaccine.At present domestic also do not have commercial effective mastitis vaccine, although commercial vaccine is abroad arranged, price is high, and effect is uncertain, is not widely used at home.Use antibiotic to remain the important means for the treatment of mammitis of cow, but because the particularity of breast tissue, and along with the extensive use of antibacterials, increasing of Resistant strain, antibacterial is more and more strong to the drug resistance of common antibiotics, the invalid situation of antibiotic therapy often occurs, this selects to bring very large difficulty for the medication for the treatment of mammitis of cow.Because antibiotic use causes abandoning of great deal of milk, make the cattle farm be subjected to more serious economic loss simultaneously.
Chinese medicine has noresidue, has no side effect, and life-time service can not produce the advantages such as public health security problem such as drug resistance, so that Chinese medicine is representing its advantage aspect the control mammitis of cow gradually.More through the Chinese medicine composition of retrieving present relevant treatment mammitis of cow, open (bulletin) numbers 101134074, its component is Herba Violae, Radix Salviae Miltiorrhizae, Spina Gleditsiae, Flos Lonicerae, Fructus Chebulae, Flos Carthami, Caulis Spatholobi, Semen Vaccariae, Radix Glycyrrhizae; Open (bulletin) numbers 101134080, its component Fructus Forsythiae, Folium Isatidis, Flos Carthami, Caulis Spatholobi, Flos Lonicerae, Bulbus Fritillariae Thunbergii; Open (bulletin) numbers 101209310, its component is Rhizoma Cimicifugae, Radix Et Rhizoma Rhei, Herba Houttuyniae; Open (bulletin) numbers 1965976, its component is Herba Taraxaci, Flos Lonicerae, Herba Violae, Radix Angelicae Sinensis, Fructus Trichosanthis, Fructus Arctii, Rhizoma Chuanxiong, Pericarpium Citri Reticulatae Viride, Radix Scutellariae, Fructus Forsythiae; Open (bulletin) numbers 101297899, its component is Herba Taraxaci, Herba Violae, Flos Lonicerae, Retinervus Luffae Fructus, Semen Vaccariae, Fructus Trichosanthis; Open (bulletin) numbers 101297857, its component is the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, Flos Lonicerae, Poria; Open (bulletin) numbers 101322779, its component is Herba Violae, Herba Taraxaci, Fructus Forsythiae, Rhizoma Coptidis; Open (bulletin) numbers 101417045, its component is Herba Taraxaci, Semen Vaccariae, Medulla Tetrapanacis, Flos Lonicerae, Rhizoma Coptidis, Herba Violae, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Glycyrrhizae, Herba Pteridis Multifidae, curled dock; Open (bulletin) number 101810733A, its component Herba Taraxaci, Herba Violae, the Radix Astragali, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Radix Glycyrrhizae; Open (bulletin) numbers 101612262, its component is Herba Taraxaci, Herba Violae, levamisole hydrochloride; Open (bulletin) numbers 101612335, its component is Herba Taraxaci, Flos Lonicerae, Flos Chrysanthemi Indici, Radix Angelicae Sinensis, Rhizoma Phragmitis, Fructus Gardeniae, Radix Scutellariae; Open (bulletin) numbers 101647959, its component is Realgar, Cortex Phellodendri, Borneolum Syntheticum, Radix Et Rhizoma Rhei, Herba Taraxaci, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ampelopsis, Os Draconis; Open (bulletin) number 101912520A, its component is Herba Houttuyniae, Flos Lonicerae, Pericarpium Citri Reticulatae, Radix Saposhnikoviae, Bulbus Fritillariae Uninbracteatae, Radix Trichosanthis, Radix Glycyrrhizae, the Radix Angelicae Dahuricae; Open (bulletin) number 101933995A, its component is Rhizoma Coptidis, Cortex Phellodendri, Herba Taraxaci, Semen Persicae, Fructus Gardeniae, Radix Isatidis, Herba Andrographis, Fructus Forsythiae, Nodus Nelumbinis Rhizomatis, Folium Isatidis, Myrrha, Radix Glycyrrhizae; Open (bulletin) number 102139024A, its component is for to be prepared from tens of kinds of raw materials such as Cornu Cervi, Folium Prinsepiae Utilis, Herba Tripterospermi, Rhizoma Bolbostematis, Radix Cirsii Japonicis.More than these Chinese medicine composition some shortcomings are arranged, 1. many Chinese prescription compositions are various, so cost is very high, to cattle-raising, are not suitable for promoting the use of; 2. many Chinese prescription abnormal smells from the patients are very heavy, and milch cow can not search for food voluntarily, need to gavage, and waste time and energy; 3. many Chinese prescriptions are fit to indivedual cases are carried out immunotherapy targeted autoantibody, are not suitable for cow in milk is carried out full group administration, therefore can not use on a large scale.
For these deficiencies and shortcoming, the invention provides a kind of Chinese medicine composition of preventing and treating mammitis of cow and preparation method thereof, this Chinese medicine composition reasonable recipe, preparation technology are simple, with low cost, easy to use, simultaneously drug residue free, have no side effect, cow in milk, conceived cattle can be used.Not only can effectively prevent, treat mastitis, and can improve the immune level of milch cow body, the infection of nonspecific opposing microorganism guarantees the health status of body, improves the milk cattle cultivating benefit of already helping.Through clinical trial: a milk cow recessive breast treatment effective percentage reaches 100%, and breast district effective percentage reaches more than 85%, and milch cow clinic mastitis effective percentage reaches more than 85%.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine composition of preventing and treating mammitis of cow and preparation method thereof, and the each component of this Chinese medicine composition is: Herba Taraxaci, Spica Prunellae, Pericarpium Citri Reticulatae Viride and Radix Glycyrrhizae, will mix in proportion after each component pulverizing, and dosage form is that powder gets final product.This drug regimen compatibility is reasonable, preparation technology is simple, with low cost, good palatability, easy to use, simultaneously drug residue free, have no side effect, cow in milk, conceived cattle can be used.The present invention can effectively prevent, treat mammitis of cow, reduces economic loss, improves the milk cattle cultivating benefit of already helping.Through clinical trial: a milk cow recessive breast treatment effective percentage reaches 100%, and breast district effective percentage reaches more than 85%; Milch cow clinic mastitis treated effect reaches more than 85%.During use, directly with Chinese medicine composition with feed after feedstuff mixes, cow in milk and conceived cattle all can be used.This Chinese medicine composition good palatability does not need to decoct or gavage, and is easy to use, is fit to the control of individual raiser and large-scale dairy farm mammitis of cow.
A kind of Chinese medicine composition of preventing and treating mammitis of cow of the present invention, the each component mass percent of this Chinese medicine composition is: Herba Taraxaci 20-80%, Spica Prunellae 10-40%, Pericarpium Citri Reticulatae Viride 5-30% and Radix Glycyrrhizae 5-10% make.
The each component mass percent of this Chinese medicine composition is: Herba Taraxaci 35-70%, Spica Prunellae 15-35%, Pericarpium Citri Reticulatae Viride 9-22% and Radix Glycyrrhizae 6-8% make.
The preparation method of described control mammitis of cow Chinese medicine composition is pulverized each component of Herba Taraxaci, Spica Prunellae, Pericarpium Citri Reticulatae Viride and Radix Glycyrrhizae, mixes in proportion again, and dosage form is that powder gets final product.
A kind of Chinese medicine composition of preventing and treating mammitis of cow of the present invention compared with prior art its characteristics is:
1. Chinese herbal medicine of the present invention makes up totally four kinds of components, and cheap, and cost is very low, is fit to extensively promote the use of;
2. the Chinese herbal medicine abnormal smells from the patient that comprises of the present invention is very little, good palatability, can with feedstuff mixed feeding or Direct-fed, do not need to gavage, conveniently save trouble, saved manpower labour cost, be fit to large-scale administration;
3. herbal prescription of the present invention is reasonable, to the not taboo of conceived milch cow, is well suited for the full group of cow in milk administration, and the scope of application is extensive;
4. Chinese herbal medicine combination of the present invention; use rear drug residue free, have no side effect; for a long time interval administration; the whole immune level that improves the milch cow body; thereby improve the ability of the nonspecific opposing infected by microbes of body; effectively the generation of prevention mammitis of cow reduces economic loss, the benefit thereby the raising milk cattle cultivating helps already.
The specific embodiment
Embodiment 1
Take by weighing respectively by mass percentage Herba Taraxaci 20%, Spica Prunellae 40%, Pericarpium Citri Reticulatae Viride 30% and Radix Glycyrrhizae 10%, each component is pulverized respectively, mix homogeneously then, dosage form is that powder gets final product.
Embodiment 2
Take by weighing by mass percentage Herba Taraxaci 80%, Spica Prunellae 10%, Pericarpium Citri Reticulatae Viride 5% and Radix Glycyrrhizae 5%, each component is pulverized respectively, mix homogeneously then, dosage form is that powder gets final product.
Embodiment 3
Take by weighing by mass percentage Herba Taraxaci 60%, Spica Prunellae 25%, Pericarpium Citri Reticulatae Viride 8% and Radix Glycyrrhizae 7%, each component is pulverized respectively, mix homogeneously then, dosage form is that powder gets final product.
Embodiment 4
Take by weighing by mass percentage Herba Taraxaci 35%, Spica Prunellae 35%, Pericarpium Citri Reticulatae Viride 22% and Radix Glycyrrhizae 8%, each component is pulverized respectively, mix homogeneously then, dosage form is that powder gets final product.
Embodiment 5
Take by weighing by mass percentage Herba Taraxaci 70%, Spica Prunellae 15%, Pericarpium Citri Reticulatae Viride 9% and Radix Glycyrrhizae 6%, each component is pulverized respectively, mix homogeneously then, dosage form is that powder gets final product.
Embodiment 6
Take by weighing by mass percentage Herba Taraxaci 50%, Spica Prunellae 30%, Pericarpium Citri Reticulatae Viride 13% and Radix Glycyrrhizae 7%, each component is pulverized respectively, mix homogeneously then, dosage form is that powder gets final product.
Press the Chinese medicine composition of any one acquisition of embodiment 1-6; during use; directly with Chinese medicine composition with feed after feedstuff mixes; for full group cow in milk or latent mammitis milch cow; dosage regimen is: 0.2 thousand g/timess/head, 1-3 times/day, 3-5 days is a course for the treatment of; but rechallenge after interval 1-2 month can carry out the administration of long-term interval.For the milch cow that the mastitis clinical symptoms occurs, such as breast redness, newborn, the cotton-shaped breast of water sample and peptonized milk etc., dosage regimen is: 0.2 thousand g/timess/head, 2-3 times/day, 5-7 days is a course for the treatment of.This Chinese medicine composition good palatability does not need to decoct or gavage, and is easy to use.
A kind of Chinese medicine composition of preventing and treating mammitis of cow of the present invention and preparation method thereof, by cow in milk being carried out full group administration, can wholely improve the milch cow immunity level, thereby improve the ability of the nonspecific opposing infected by microbes of body, the effectively generation of prevention mammitis of cow, reduce economic loss, the benefit thereby the raising milk cattle cultivating helps already.

Claims (3)

1. Chinese medicine composition of preventing and treating mammitis of cow, it is characterized in that the each component mass percent of this Chinese medicine composition is: Herba Taraxaci 20-80%, Spica Prunellae 10-40%, Pericarpium Citri Reticulatae Viride 5-30% and Radix Glycyrrhizae 5-10% make.
2. the Chinese medicine composition of control mammitis of cow according to claim 1, it is characterized in that the each component mass percent of this Chinese medicine composition is: Herba Taraxaci 35-70%, Spica Prunellae 15-35%, Pericarpium Citri Reticulatae Viride 9-22% and Radix Glycyrrhizae 6-8% make.
3. the preparation method of control mammitis of cow Chinese medicine composition according to claim 1 and 2 is characterized in that each component of Herba Taraxaci, Spica Prunellae, Pericarpium Citri Reticulatae Viride and Radix Glycyrrhizae is pulverized, and mixes in proportion again, and dosage form is that powder gets final product.
CN201210402202XA 2012-10-22 2012-10-22 Chinese medicine composition for preventing and treating mastitis of dairy cattle and preparation method thereof Pending CN102846795A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
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CN103239651A (en) * 2013-05-16 2013-08-14 孙霞 Traditional Chinese medicine for treating subclinical mastitis for dairy cow
CN104069206A (en) * 2013-03-28 2014-10-01 长江大学 Traditional Chinese herbal formula for treating milk cow postpartum mastitis
CN104431485A (en) * 2014-11-29 2015-03-25 汝州羊羊羊牧业科技有限公司 Feed for cattle and sheep in lactation period
CN105104753A (en) * 2015-08-26 2015-12-02 新昌县大成生物科技有限公司 Feed additive for treating recessive cow mastitis of dairy cows
CN105124296A (en) * 2015-09-17 2015-12-09 广西百强水牛奶业股份有限公司 Specific feed for dairy buffalo
CN105124295A (en) * 2015-09-17 2015-12-09 广西百强水牛奶业股份有限公司 Dairy buffalo feed for improving milk flavor
CN105169023A (en) * 2015-09-06 2015-12-23 王璐 Veterinary drug for treating mastopathy of livestock
CN107095940A (en) * 2017-06-12 2017-08-29 张从娥 A kind of natural plants combination preventing and treating mastitis for milk cows and ncreasing milk and fatting cow preparation
CN113117029A (en) * 2021-04-22 2021-07-16 章国忠 Traditional Chinese medicine composition for reducing somatic cell count in milk and preparation method thereof

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104069206A (en) * 2013-03-28 2014-10-01 长江大学 Traditional Chinese herbal formula for treating milk cow postpartum mastitis
CN103239651A (en) * 2013-05-16 2013-08-14 孙霞 Traditional Chinese medicine for treating subclinical mastitis for dairy cow
CN103239651B (en) * 2013-05-16 2015-04-08 青岛华仁技术孵化器有限公司 Traditional Chinese medicine for treating subclinical mastitis for dairy cow
CN104431485A (en) * 2014-11-29 2015-03-25 汝州羊羊羊牧业科技有限公司 Feed for cattle and sheep in lactation period
CN105104753A (en) * 2015-08-26 2015-12-02 新昌县大成生物科技有限公司 Feed additive for treating recessive cow mastitis of dairy cows
CN105169023A (en) * 2015-09-06 2015-12-23 王璐 Veterinary drug for treating mastopathy of livestock
CN105124296A (en) * 2015-09-17 2015-12-09 广西百强水牛奶业股份有限公司 Specific feed for dairy buffalo
CN105124295A (en) * 2015-09-17 2015-12-09 广西百强水牛奶业股份有限公司 Dairy buffalo feed for improving milk flavor
CN107095940A (en) * 2017-06-12 2017-08-29 张从娥 A kind of natural plants combination preventing and treating mastitis for milk cows and ncreasing milk and fatting cow preparation
CN113117029A (en) * 2021-04-22 2021-07-16 章国忠 Traditional Chinese medicine composition for reducing somatic cell count in milk and preparation method thereof

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Application publication date: 20130102