CN102657729A - Traditional Chinese medicine injection used in treatment of dairy cow mastitis and preparation method thereof - Google Patents

Abstract

The invention relates to a traditional Chinese medicine injection used in the treatment of dairy cow mastitis. The traditional Chinese medicine injection is characterized by being prepared from the following raw material components in parts by weight: 1-5 parts of burdock, 1-5 parts of honeysuckle, 1-3 parts of green tangerine peel, 1-3 parts of radix scutellariae, and 1-2 parts of salvia miltiorrhiza. A preparation method of the compound traditional Chinese medicine injection used in the treatment of dairy cow mastitis comprises the following steps: (1) weighing 1-5 parts of burdock, 1-5 parts of honeysuckle, 1-3 parts of green tangerine peel, 1-3 parts of radix scutellariae, and 1-2 parts of salvia miltiorrhiza by weight; and (2) weighing the five traditional Chinese medicines, adding 10 times water in each component for decoction twice for 1.5 hours each time, filtering decoction fluid, mixing filtrate, concentrating to proper amount, chilling, adding ethanol to enable the ethanol content to be 65%, standing for 24 hours, filtering, recovering ethanol from filtrate, concentrating to proper amount, adding proper amount of water, refrigerating for 48 hours, filtering, adding water to constant volume, adding sodium benzoate, uniformly mixing, filling, and sterilizing, thus obtaining the traditional Chinese medicine injection. The invention provides the traditional Chinese medicine injection which is mainly used in the prevention and treatment of dairy cow mastitis for the breeding industry of dairy cows, and has the characteristics of quickly taking effect and being definite in curative effect without medicine residue or withdrawal period.

Description

Be used to Chinese medicine of treating mammitis of cow and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine injection products, particularly relate to a kind of Chinese medicine that is used to treat mammitis of cow.

Background technology

Mammitis of cow be milch cow modal also be a kind of disease that causes the dairy economic loss maximum.The Therapeutic Principle commonly used of mastitis is an anti-inflammation, improves environment, strengthens the animal resistance.Antibiotic is the most frequently used medicine of anti-inflammation, and like penicillin, ampicillin, streptomycin etc., curative effect is all better.Cure purpose though use the antibiotic therapy mastitis can reach antibacterial, do not have the effect that long-term promotion mammary gland recovers, the ill nipple milk yield in recovery from illness back descends, and is reaching in the treatment phase of first quarter moon, and the milk anorexia usefulness of producing causes the production economic loss.Even more serious is; Some microorganism can produce obstinate Drug resistance to antibiotic; Not only reduce its curative effect, and a large amount of antibiotic remainss of the toxin of a large amount of pathogenic microorganisms in the mastitis disease Lac Bovis seu Bubali juice and generation thereof or generation after treatment, direct harm humans is healthy.Along with people's to food safety requirements improve constantly with country to the stricter requirement of quality of dairy products, the antibiotic of clinical control mastitis commonly used is owing to exist drug residue to be limited the use of gradually.

Summary of the invention

The objective of the invention is the deficiency to prior art, a kind of herbal mixture injection that is used to treat mammitis of cow and preparation method thereof is provided.

A kind of herbal mixture injection that is used to treat mammitis of cow is characterized in that, it is characterized in that: be made up of the following raw materials according component, by weight meter: Fructus Arctii 1-5 part, Flos Lonicerae 1-5 part, Pericarpium Citri Reticulatae Viride 1-3 part, Radix Scutellariae 1-3 part, Radix Salviae Miltiorrhizae 1-2 part.

The above-mentioned herbal mixture injection that is used to treat mammitis of cow, it is 4 parts of Fructus Arctiis that preferable component is formed, 4 parts of Flos Loniceraes, 2 parts on Pericarpium Citri Reticulatae Viride, 2 parts of Radix Scutellariaes, 1 part of Radix Salviae Miltiorrhizae.

A kind of method for preparing that is used to treat the herbal mixture injection of mammitis of cow, carry out as follows:

(1) takes by weighing Fructus Arctii 1-5 part by weight, Flos Lonicerae 1-5 part, Pericarpium Citri Reticulatae Viride 1-3 part, Radix Scutellariae 1-3 part, Radix Salviae Miltiorrhizae 1-2 part;

(2) take by weighing above 5 kinds of Chinese medicines, each component adds 10 times of decoctings respectively and boils secondary, and each 1.5 hours, decocting liquid filtered, and filtrating merges, and is concentrated into an amount of; Put coldly, add ethanol and make and contain the alcohol amount and reach 65%, left standstill 24 hours, filter filtrate recycling ethanol; Be concentrated in right amount, it is an amount of to add water, and cold preservation 48 hours is filtered, and adds the water standardize solution; Add sodium benzoate, mixing, fill, sterilization promptly gets.

The invention has the beneficial effects as follows: for milk cattle cultivating already provides a kind of Chinese medicine that is mainly used in the control mammitis of cow, have instant effect, curative effect really, no drug residue, do not need the characteristics of off-drug period.

Chinese herbal medicine belongs to natural product; Contain multiple biological effective components, have antibiotic, antiinflammatory, be difficult for producing bacterial drug resistance, characteristics such as internal metabolism is very fast, high-efficiency low-toxicity, noresidue or low-residual, after treatment, generally do not need the off-drug period; Alternative chemical synthetic drug; Both but bacteriostasis and sterilization, enhancing immunity function of animal can be used as the metabolism that extraordinary bioactive additive is regulated body again, promoted the absorption of nutrient substance.

Composition principle of the present invention is: Fructus Arctii dispelling wind and heat pathogens in the side, removing toxic substances and promoting subsidence of swelling; The Flos Lonicerae heat-clearing and toxic substances removing, dispelling wind and heat pathogens; Pericarpium Citri Reticulatae Viride drainage dispelling the stagnated QI, removing food stagnancyization stagnates; The Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication; The Radix Salviae Miltiorrhizae promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle; All medicines share, heat-clearing and toxic substances removing, and the eliminating carbuncle eliminating stagnation can be dredged strongly fragrant lactogenesis.

The specific embodiment

Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:

Embodiment 1

A kind of herbal mixture injection that is used to treat mammitis of cow is made up of the following raw materials according component: Fructus Arctii 40g, Flos Lonicerae 40g, Pericarpium Citri Reticulatae Viride 30g, Radix Scutellariae 20g, Radix Salviae Miltiorrhizae 10g.

Its preparation method carries out as follows:

(1) takes by weighing Fructus Arctii 40g by weight, Flos Lonicerae 40g, Pericarpium Citri Reticulatae Viride 30g, Radix Scutellariae 20g, Radix Salviae Miltiorrhizae 10g;

(2) take by weighing above 5 kinds of Chinese medicines, each component adds 10 times of decoctings respectively and boils secondary, and each 1.5 hours, decocting liquid filtered, and filtrating merges, and is concentrated into an amount of; Put coldly, add ethanol and make and contain the alcohol amount and reach 65%, left standstill 24 hours, filter filtrate recycling ethanol; Be concentrated in right amount, it is an amount of to add water, and cold preservation 48 hours is filtered, and adds the water standardize solution; Add sodium benzoate, mixing, fill, sterilization promptly gets.

Embodiment 2

A kind of herbal mixture injection that is used to treat mammitis of cow is made up of the following raw materials according component: Fructus Arctii 50g, Flos Lonicerae 40g, Pericarpium Citri Reticulatae Viride 30g, Radix Scutellariae 30g, Radix Salviae Miltiorrhizae 10g.

Its preparation method carries out as follows:

(1) takes by weighing Fructus Arctii 50g by weight, Flos Lonicerae 40g, Pericarpium Citri Reticulatae Viride 30g, Radix Scutellariae 30g, Radix Salviae Miltiorrhizae 10g;

(2) take by weighing above 5 kinds of Chinese medicines, each component adds 10 times of decoctings respectively and boils secondary, and each 1.5 hours, decocting liquid filtered, and filtrating merges, and is concentrated into an amount of; Put coldly, add ethanol and make and contain the alcohol amount and reach 65%, left standstill 24 hours, filter filtrate recycling ethanol; Be concentrated in right amount, it is an amount of to add water, and cold preservation 48 hours is filtered, and adds the water standardize solution; Add sodium benzoate, mixing, fill, sterilization promptly gets.

Embodiment 3

A kind of herbal mixture injection that is used to treat mammitis of cow is made up of the following raw materials according component: Fructus Arctii 40g, Flos Lonicerae 40g, Pericarpium Citri Reticulatae Viride 20g, Radix Scutellariae 20g, Radix Salviae Miltiorrhizae 10g.

Its preparation method carries out as follows:

(1) takes by weighing Fructus Arctii 40g by weight, Flos Lonicerae 40g, Pericarpium Citri Reticulatae Viride 20g, Radix Scutellariae 20g, Radix Salviae Miltiorrhizae 10g;

(2) take by weighing above 5 kinds of Chinese medicines, each component adds 10 times of decoctings respectively and boils secondary, and each 1.5 hours, decocting liquid filtered, and filtrating merges, and is concentrated into an amount of; Put coldly, add ethanol and make and contain the alcohol amount and reach 65%, left standstill 24 hours, filter filtrate recycling ethanol; Be concentrated in right amount, it is an amount of to add water, and cold preservation 48 hours is filtered, and adds the water standardize solution; Add sodium benzoate, mixing, fill, sterilization promptly gets.

Embodiment 4

A kind of herbal mixture injection that is used to treat mammitis of cow is made up of the following raw materials according component: Fructus Arctii 40g, Flos Lonicerae 30g, Pericarpium Citri Reticulatae Viride 20g, Radix Scutellariae 20g, Radix Salviae Miltiorrhizae 10g.

Its preparation method carries out as follows:

(1) takes by weighing Fructus Arctii 40g by weight, Flos Lonicerae 30g, Pericarpium Citri Reticulatae Viride 20g, Radix Scutellariae 20g, Radix Salviae Miltiorrhizae 10g;

(2) take by weighing above 5 kinds of Chinese medicines, each component adds 10 times of decoctings respectively and boils secondary, and each 1.5 hours, decocting liquid filtered, and filtrating merges, and is concentrated into an amount of; Put coldly, add ethanol and make and contain the alcohol amount and reach 65%, left standstill 24 hours, filter filtrate recycling ethanol; Be concentrated in right amount, it is an amount of to add water, and cold preservation 48 hours is filtered, and adds the water standardize solution; Add sodium benzoate, mixing, fill, sterilization promptly gets.

Embodiment 5

Clinical trial: 75 nose heave disease milch cows in 353 of the raising of Jinghai dairy farm; Clinical symptoms: dairy cow milk is faint yellow water sample or water sample viscosity liquid redly; General Symptoms in various degree appears simultaneously, like loss of appetite or useless exhausted, more than the fervescence to 41 ℃; Breathe and palpitating speed lethargy.75 nose heave disease milch cows are divided into 4 groups, satisfy respectively with the treatment of embodiment 1-4 Chinese medicine, continuous use is gathered the milk inspection and is identified curative effect after 5 days.The result proves that it is 92% that medicine of the present invention is totally treated effective percentage; In 4 groups of milch cows among the embodiment 3 cure rate the highest; Reach 97%, embodiment 1-2,4 medicament administration group cure rates are between 90.2-92.3%, and above result shows that this medicine has therapeutical effect to acute mastitis.16 healthy cows are used the herbal mixture injection of embodiment 1-4 respectively, continuous use after 10 days the milk cattle sign normal, do not show toxic and side effects.

Above-mentioned detailed description of herbal mixture injection of being used to treat mammitis of cow and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore, variation and modification not breaking away under the general plotting of the present invention should belong within protection scope of the present invention.

Claims (4)

1. a Chinese medicine that is used to treat mammitis of cow is characterized in that, it is characterized in that: be made up of the following raw materials according component, by weight meter: Fructus Arctii 1-5 part, Flos Lonicerae 1-5 part, Pericarpium Citri Reticulatae Viride 1-3 part, Radix Scutellariae 1-3 part, Radix Salviae Miltiorrhizae 1-2 part.

2. the Chinese medicine that is used to treat mammitis of cow according to claim 3 is characterized in that, 4 parts of Fructus Arctiis, 4 parts of Flos Loniceraes, 2 parts on Pericarpium Citri Reticulatae Viride, 2 parts of Radix Scutellariaes, 1 part of Radix Salviae Miltiorrhizae.

3. a method for preparing that is used to treat the Chinese medicine of mammitis of cow is characterized in that, carries out as follows:

(1) takes by weighing Fructus Arctii 1-5 part by weight, Flos Lonicerae 1-5 part, Pericarpium Citri Reticulatae Viride 1-3 part, Radix Scutellariae 1-3 part, Radix Salviae Miltiorrhizae 1-2 part;

(2) take by weighing above 5 kinds of Chinese medicines, each component adds 10 times of decoctings respectively and boils secondary, and each 1.5 hours, decocting liquid filtered, and filtrating merges, and is concentrated into an amount of; Put coldly, add ethanol and make and contain the alcohol amount and reach 65%, left standstill 24 hours, filter filtrate recycling ethanol; Be concentrated in right amount, it is an amount of to add water, and cold preservation 48 hours is filtered, and adds the water standardize solution; Add sodium benzoate, mixing, fill, sterilization promptly gets.

4. according to the method for preparing of Chinese medicine that is used to treat mammitis of cow of claim 3, it is characterized in that, carry out as follows:

(1) takes by weighing 4 parts of Fructus Arctiis by weight, 4 parts of Flos Loniceraes, 2 parts on Pericarpium Citri Reticulatae Viride, 2 parts of Radix Scutellariaes, 1 part of Radix Salviae Miltiorrhizae;

(2) take by weighing above 5 kinds of Chinese medicines, each component adds 10 times of decoctings respectively and boils secondary, and each 1.5 hours, decocting liquid filtered, and filtrating merges, and is concentrated into an amount of; Put coldly, add ethanol and make and contain the alcohol amount and reach 65%, left standstill 24 hours, filter filtrate recycling ethanol; Be concentrated in right amount, it is an amount of to add water, and cold preservation 48 hours is filtered, and adds the water standardize solution; Add sodium benzoate, mixing, fill, sterilization promptly gets.