CN103768362A - Chinese veterinary drug used for preventing and treating mastitis of dairy cow and preparation method thereof - Google Patents
Chinese veterinary drug used for preventing and treating mastitis of dairy cow and preparation method thereof Download PDFInfo
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- CN103768362A CN103768362A CN201210405811.0A CN201210405811A CN103768362A CN 103768362 A CN103768362 A CN 103768362A CN 201210405811 A CN201210405811 A CN 201210405811A CN 103768362 A CN103768362 A CN 103768362A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 208000004396 mastitis Diseases 0.000 title abstract description 8
- 235000013365 dairy product Nutrition 0.000 title abstract description 6
- 239000000273 veterinary drug Substances 0.000 title abstract description 6
- 230000002265 prevention Effects 0.000 claims abstract description 15
- 239000000284 extract Substances 0.000 claims abstract description 10
- 208000031462 Bovine Mastitis Diseases 0.000 claims description 25
- 241000411851 herbal medicine Species 0.000 claims description 20
- 239000003814 drug Substances 0.000 claims description 17
- 241000628997 Flos Species 0.000 claims description 13
- 239000009636 Huang Qi Substances 0.000 claims description 9
- 229940079593 drug Drugs 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 8
- 241000195474 Sargassum Species 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 3
- 241000283690 Bos taurus Species 0.000 abstract description 11
- 201000010099 disease Diseases 0.000 abstract description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 4
- 206010007247 Carbuncle Diseases 0.000 abstract description 3
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 3
- 239000003640 drug residue Substances 0.000 abstract description 3
- 230000036039 immunity Effects 0.000 abstract description 3
- 244000052616 bacterial pathogen Species 0.000 abstract description 2
- 231100000957 no side effect Toxicity 0.000 abstract description 2
- 230000008961 swelling Effects 0.000 abstract description 2
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241000512259 Ascophyllum nodosum Species 0.000 abstract 1
- 241001061264 Astragalus Species 0.000 abstract 1
- 235000010110 Astragalus glycyphyllos Nutrition 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 241000244987 Daiswa polyphylla Species 0.000 abstract 1
- 241000123589 Dipsacus Species 0.000 abstract 1
- 241000555682 Forsythia x intermedia Species 0.000 abstract 1
- 241000935235 Fritillaria meleagris Species 0.000 abstract 1
- 241000931143 Gleditsia sinensis Species 0.000 abstract 1
- 235000005206 Hibiscus Nutrition 0.000 abstract 1
- 235000007185 Hibiscus lunariifolius Nutrition 0.000 abstract 1
- 244000048199 Hibiscus mutabilis Species 0.000 abstract 1
- 235000003973 Hibiscus mutabilis Nutrition 0.000 abstract 1
- 244000284380 Hibiscus rosa sinensis Species 0.000 abstract 1
- 241000244365 Ligusticum sinense Species 0.000 abstract 1
- 241000219138 Luffa Species 0.000 abstract 1
- 235000003956 Luffa Nutrition 0.000 abstract 1
- 244000302544 Luffa aegyptiaca Species 0.000 abstract 1
- 235000009814 Luffa aegyptiaca Nutrition 0.000 abstract 1
- 241000972673 Phellodendron amurense Species 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 244000290970 Tetrapanax papyrifer Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000009776 industrial production Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000008267 milk Substances 0.000 description 3
- 235000013336 milk Nutrition 0.000 description 3
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- 241001430197 Mollicutes Species 0.000 description 1
- 241000204031 Mycoplasma Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
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- 230000036528 appetite Effects 0.000 description 1
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- 238000009360 aquaculture Methods 0.000 description 1
- 244000144974 aquaculture Species 0.000 description 1
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- 230000017531 blood circulation Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
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- 239000002158 endotoxin Substances 0.000 description 1
- 229940023064 escherichia coli Drugs 0.000 description 1
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- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000001983 lactogenic effect Effects 0.000 description 1
- 210000005075 mammary gland Anatomy 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 229940115920 streptococcus dysgalactiae Drugs 0.000 description 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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Abstract
The invention relates to a Chinese veterinary drug used for preventing and treating mastitis of dairy cows and a preparation method thereof. The Chinese veterinary drug comprises, by weight, 10 to 20 parts of dandelion, 10 to 20 parts of honeysuckle flower, 5 to 10 parts of fructus forsythia extract, 5 to 10 parts of vegetable sponge of luffa, 5 to 10 parts of ricepaperplant pith, 5 to 10 parts of cotton rose hibiscus leaf, 5 to 10 parts of thunberg fritillary bulb, 5 to 10 parts of Chinese honeylocust spine, 5 to 10 parts of Paris polyphylla, 5 to 10 parts of milkvetch root and 5 to 10 parts of Sichuan lovage rhizome. One or more selected from the group consisting of kelp, alga, amur cork-tree bark, Chinese angelica, safflower, unprocessed rehmannia root and Himalayan teasel root can be added. The Chinese veterinary drug used for preventing and treating mastitis of dairy cows prepared in the invention is a natural purely Chinese herbal preparation, exerts a good antibacterial effect on most mastitis pathogenic bacteria, can clear away heat and toxic materials, eliminating swelling, dispelling carbuncle, relieving pain, expelling pus, resisting oxidation and improving cow immunity and capability of resisting diseases, is safe and green, has no drug residue and no side effects and can be well absorbed through oral administration; the preparation method is simple and suitable for industrial production; the Chinese veterinary drug has the characteristics of easy, convenient and fast usage and is more applicable to prevention and treatment of mastitis of dairy cow on a large-scale farm compared with other dosage forms.
Description
Technical field
The invention belongs to field of medicine preparing technology, herbal medicine of especially a kind of prevention and treatment bovine mastitis and preparation method thereof.
Background technology
Along with the fast development of China's economy, improving constantly of living standards of the people, people are also constantly soaring to the demand of milk, but along with the increase of milch cow quantity, bovine mastitis has just become a very common disease, dairy farmer has many knotty problems in the time for the treatment of, but the residue problem of medicine, bovine mastitis be one of major reason causing milch cow production economy loss, bovine mastitis not only affects milk yield, milk quality, cause economic loss, and the health that jeopardizes people, therefore, bovine mastitis is a difficult problem for development dairy puzzlement all the time.
Up to the present, people have isolated 150 kinds of pathogenic microorganisms from cow mammary gland tissue, and modal have 23 kinds, wherein 14 kinds, antibacterial, 2 kinds of mycoplasmas, 7 kinds, fungus and virus.What wherein sickness rate was the highest is staphylococcus aureus, escherichia coli, streptococcus, and mycoplasma, fungus-caused mastitis sickness rate rise year by year in recent years.
The present invention utilizes domestic a large amount of Chinese herbal medicine resource, according to Chinese medical theory, rationally utilizing Chinese herbal medicine function to cure mainly reasonable compatibility uses a kind of prevention of developing and treats herbal medicine of bovine mastitis and preparation method thereof, this product is pure Chinese medicinal preparation, most of mastitis pathogenic bacteriums are had to stronger antibacterial effect, can eliminate bacterial endotoxin and inflammation-inhibiting development, can significantly suppress staphylococcus aureus, Hemolytic streptococcus, streptococcus dysgalactiae, streptococcus pneumoniae, escherichia coli, the various bacteria growths such as Pseudomonas aeruginosa, this product can regulate milch cow smooth muscle irritability, improve blood circulation, promote galactopoiesis lactogenic pain relieving, for milch cow acute mastitis, galactopoiesis is not smooth, breast amount reduces or stops, mammary swelling, hardening, heat, pain, refusal suckling, poor appetite, the symptoms such as lassitude, there is heat-clearing and toxic substances removing, Sweeling-eliminating medicine powder carbuncle, pain relieving evacuation of pus, antioxidation, strengthen milch cow immunity and the anti-disease ability of body, and safe green no drug residue, have no side effect.Have dosage accurately, steady quality, transportation, store, carry, apply all more convenient; Mechanization production, output is large, and cost is low, and sanitary standard also easily reaches.
Summary of the invention
The object of the invention is to overcome the deficiency of existing preparation and technology, propose a kind of safety, green, no drug residue, compatibility rationally, convenient drug administration, technique be simple, reliable for effect, what be easy to promote a kind ofly prevents and treats herbal medicine of bovine mastitis and preparation method thereof.
The technical scheme that the present invention realizes object is:
A herbal medicine for prevention and treatment bovine mastitis, forms component and mass fraction thereof and is respectively:
Herba Taraxaci 10-20 part; Flos Lonicerae 10-20 part;
Fructus Forsythiae extract 5-10 part; Retinervus Luffae Fructus 5-10 part;
Medulla Tetrapanacis 5-10 part; Folium Hibisci Mutabilis 5-10 part;
Bulbus Fritillariae Thunbergii 5-10 part; Spina Gleditsiae 5-10 part;
Rhizoma Paridis 5-10 part; Radix Astragali 5-10 part;
Rhizoma Chuanxiong 5-10 part.
Can add one or more in Thallus Laminariae (Thallus Eckloniae), Sargassum, Cortex Phellodendri, Radix Angelicae Sinensis, Flos Carthami, the Radix Rehmanniae, Radix Dipsaci.
Herbal medicine of a kind of prevention and treatment bovine mastitis and preparation method thereof, step is:
(1) adopt Chinese medicine grinder to pulverize separately Herba Taraxaci, Retinervus Luffae Fructus, Medulla Tetrapanacis, Folium Hibisci Mutabilis, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, the Radix Astragali and Rhizoma Chuanxiong, cross respectively 80 mesh standard sieves, obtain Chinese crude drug fine powder;
(2) Flos Lonicerae, Rhizoma Paridis are pulverized respectively, crossed 80 mesh standard sieves;
(3) take the Fructus Forsythiae extract of recipe quantity for subsequent use;
(4) take each Chinese crude drug fine powder in (1) by prescription, mix 15 minutes;
(5) (3) are dropped in (4) and mixed 15 minutes;
(6) again (2) are dropped in (5) and mixed 20 minutes, obtain the herbal medicine of a kind of prevention and treatment bovine mastitis.
Advantage of the present invention and beneficial effect are:
1, the present invention has innovated the Chinese herbal medicine compatibility agent of control bovine mastitis, fully demonstrate the advantage in the Chinese herbal medicine application of Chinese medicine big country, the important breakthrough of the new application technology of domestic herbal prescription, for Chinese medicine novel composing prescription has been opened up in the treatment of domestic bovine mastitis.
2, the present invention has improved the first traditional treatment mode of controlling after being ill, can, by feedstuff or the method such as feed, have the effects such as heat-clearing and toxic substances removing, Sweeling-eliminating medicine powder carbuncle, pain relieving evacuation of pus, antioxidation, to strengthen the anti-disease ability of milch cow immunity and body.
3, the technique the present invention relates to has that production equipment is simple, technique is simple, processing ease, advantage easy to use, to be applicable to industrialization, make up the blank of bovine mastitis treatment aspect, domestic veterinary drug market, innovate the Chinese prescription of reasonable compatibility, can realize rapidly industrialization, promote the development of aquaculture.
The specific embodiment
Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
Herba Taraxaci 10-20 part;
Flos Lonicerae 10-20 part;
Fructus Forsythiae extract 5-10 part;
Retinervus Luffae Fructus 5-10 part;
Medulla Tetrapanacis 5-10 part;
Folium Hibisci Mutabilis 5-10 part;
Bulbus Fritillariae Thunbergii 5-10 part;
Spina Gleditsiae 5-10 part;
Rhizoma Paridis 5-10 part;
Radix Astragali 5-10 part;
Rhizoma Chuanxiong 5-10 part.
Can add one or more in Thallus Laminariae (Thallus Eckloniae), Sargassum, Cortex Phellodendri, Radix Angelicae Sinensis, Flos Carthami, the Radix Rehmanniae, Radix Dipsaci.
Embodiment 1:
A herbal medicine for prevention and treatment bovine mastitis, it forms component and parts by weight are respectively (by every bag of 100g supplementary material proportioning, following examples are same):
Herba Taraxaci 15g;
Flos Lonicerae 15g;
Fructus Forsythiae extract 8g;
Retinervus Luffae Fructus 8g;
Medulla Tetrapanacis 8g;
Folium Hibisci Mutabilis 8g;
Bulbus Fritillariae Thunbergii 8g;
Spina Gleditsiae 8g;
Rhizoma Paridis 8g;
Radix Astragali 7g;
Rhizoma Chuanxiong 7g.
Crude drug involved in the present invention all adopts the regulation of " Chinese veterinary pharmacopoeia " two Chinese crude drugs of in 2010 version and decoction pieces.
Herbal medicine of a kind of prevention and treatment bovine mastitis and preparation method thereof, comprises the steps:
(1) adopt Chinese medicine grinder to pulverize separately Herba Taraxaci, Retinervus Luffae Fructus, Medulla Tetrapanacis, Folium Hibisci Mutabilis, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, the Radix Astragali and Rhizoma Chuanxiong, cross respectively 80 mesh standard sieves, obtain Chinese crude drug fine powder;
(2) Flos Lonicerae, Rhizoma Paridis are pulverized respectively, crossed 80 mesh standard sieves;
(3) take the Fructus Forsythiae extract of recipe quantity for subsequent use;
(4) take each Chinese crude drug fine powder in (1) by prescription, mix 15 minutes;
(5) (3) are dropped in (4) and mixed 15 minutes;
(6) again (2) are dropped in (5) and mixed 20 minutes, obtain the herbal medicine of a kind of prevention and treatment bovine mastitis.
Embodiment 2:
A herbal medicine for prevention and treatment bovine mastitis, it forms component and parts by weight are respectively:
Herba Taraxaci 20g;
Flos Lonicerae 10g;
Fructus Forsythiae extract 10g;
Retinervus Luffae Fructus 10g;
Medulla Tetrapanacis 5g;
Folium Hibisci Mutabilis 5g;
Bulbus Fritillariae Thunbergii 6g;
Spina Gleditsiae 5g;
Rhizoma Paridis 8g;
Radix Astragali 8g;
Rhizoma Chuanxiong 7g;
Flos Carthami 6g.
The step of the present embodiment preparation method is same as embodiment 1.
Embodiment 3:
A herbal medicine for prevention and treatment bovine mastitis, it forms component and parts by weight are respectively:
Herba Taraxaci 10g;
Flos Lonicerae 10g;
Fructus Forsythiae extract 8g;
Retinervus Luffae Fructus 8g;
Medulla Tetrapanacis 8g;
Folium Hibisci Mutabilis 8g;
Bulbus Fritillariae Thunbergii 8g;
Spina Gleditsiae 8g;
Rhizoma Paridis 8g;
Radix Astragali 7g;
Rhizoma Chuanxiong 7g;
Thallus Laminariae (Thallus Eckloniae) 5g;
Sargassum 5g.
The step of the preparation method of the present embodiment is same as embodiment 1.
Detecting data: this invention is 98.9% for bovine mastitis prevention effective percentage, is 93.8% for bovine mastitis treatment obvious effective rate.
Claims (3)
1. one kind is prevented and treats herbal medicine of bovine mastitis and preparation method thereof, it is characterized in that: form component and mass fraction thereof and be respectively:
Herba Taraxaci 10-20 part; Flos Lonicerae 10-20 part;
Fructus Forsythiae extract 5-10 part; Retinervus Luffae Fructus 5-10 part;
Medulla Tetrapanacis 5-10 part; Folium Hibisci Mutabilis 5-10 part;
Bulbus Fritillariae Thunbergii 5-10 part; Spina Gleditsiae 5-10 part;
Rhizoma Paridis 5-10 part; Radix Astragali 5-10 part;
Rhizoma Chuanxiong 5-10 part.
2. herbal medicine of a kind of prevention according to claim 1 and treatment bovine mastitis and preparation method thereof, is characterized in that: describedly add one or more in Thallus Laminariae (Thallus Eckloniae), Sargassum, Cortex Phellodendri, Radix Angelicae Sinensis, Flos Carthami, the Radix Rehmanniae, Radix Dipsaci.
3. one kind is prevented and treats herbal medicine of bovine mastitis and preparation method thereof, it is characterized in that: the step of preparation is:
(1) adopt Chinese medicine grinder to pulverize separately Herba Taraxaci, Retinervus Luffae Fructus, Medulla Tetrapanacis, Folium Hibisci Mutabilis, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, the Radix Astragali and Rhizoma Chuanxiong, cross respectively 80 mesh standard sieves, obtain Chinese crude drug fine powder;
(2) Flos Lonicerae, Rhizoma Paridis are pulverized respectively, crossed 80 mesh standard sieves;
(3) take the Fructus Forsythiae extract of recipe quantity for subsequent use;
(4) take each Chinese crude drug fine powder in (1) by prescription, mix 15 minutes;
(5) (3) are dropped in (4) and mixed 15 minutes;
(6) again (2) are dropped in (5) and mixed 20 minutes, obtain the herbal medicine of a kind of prevention and treatment bovine mastitis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210405811.0A CN103768362A (en) | 2012-10-22 | 2012-10-22 | Chinese veterinary drug used for preventing and treating mastitis of dairy cow and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210405811.0A CN103768362A (en) | 2012-10-22 | 2012-10-22 | Chinese veterinary drug used for preventing and treating mastitis of dairy cow and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN103768362A true CN103768362A (en) | 2014-05-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201210405811.0A Pending CN103768362A (en) | 2012-10-22 | 2012-10-22 | Chinese veterinary drug used for preventing and treating mastitis of dairy cow and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800615A (en) * | 2015-03-27 | 2015-07-29 | 李博 | Chinese herbal medicine formula capable of preventing and treating subclinical mastitis of milk cow |
| CN105031428A (en) * | 2015-07-21 | 2015-11-11 | 内蒙古新开元动物药业发展有限公司 | Traditional Chinese medicine preparation for treating cow mastitis and method for preparing traditional Chinese medicine preparation |
| CN109276639A (en) * | 2018-09-28 | 2019-01-29 | 西北农林科技大学 | A composition for preventing/treating milk goat udder edema and its preparation method and application |
-
2012
- 2012-10-22 CN CN201210405811.0A patent/CN103768362A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800615A (en) * | 2015-03-27 | 2015-07-29 | 李博 | Chinese herbal medicine formula capable of preventing and treating subclinical mastitis of milk cow |
| CN105031428A (en) * | 2015-07-21 | 2015-11-11 | 内蒙古新开元动物药业发展有限公司 | Traditional Chinese medicine preparation for treating cow mastitis and method for preparing traditional Chinese medicine preparation |
| CN109276639A (en) * | 2018-09-28 | 2019-01-29 | 西北农林科技大学 | A composition for preventing/treating milk goat udder edema and its preparation method and application |
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Application publication date: 20140507 |