CN104173604A - Traditional Chinese medicine composition for improving piglet anti-infection immunization function and preparation method thereof - Google Patents

Abstract

The invention relates to a traditional Chinese medicine composition for improving a piglet anti-infection immunization function and a preparation method thereof. The traditional Chinese medicine composition comprises, by weight, 5-10 parts of herba houttuyniae, 5-10 parts of cortex phellodendri, 5-10 parts of isatis root, 5-15 parts of ash bark, 5-15 parts of polygonum viviparum, 5-15 parts of coptis root, 10-20 parts of radix astragali, 10-20 parts of Chinese angelica, 3-5 parts of buffalo horn concentrate powder, 10-20 parts of herba violae and 3-5 parts of licorice root. The traditional Chinese medicine composition for improving a piglet anti-infection immunization function comprises the pure natural Chinese herbal medicines, can treat piglet early-onset escherichia coli-caused disease and adjust piglet internal organ balance and immunity, is safe and eco-friendly, does not produce medicine residue and can still produce effects on strains having resistance to antibiotic. The traditional Chinese medicine composition has good oral absorbency. The preparation method has simple processes and is suitable for industrial production. The traditional Chinese medicine composition has the characteristics of use simpleness, convenience and speediness. Compared with other dosage forms, the traditional Chinese medicine composition is suitable for treating piglet early-onset escherichia coli-caused disease in a large-scale culture field.

Description

A kind of Chinese medicine composition that strengthens piglet anti-infectious immunity function and preparation method thereof

Technical field

The invention belongs to field of medicine preparing technology, especially a kind of Chinese medicine composition that strengthens piglet anti-infectious immunity function and preparation method thereof

Background technology

Early onset colibacillosis is that the one of newborn piglet is acute, height lethal infectious disease.Primary disease is the piglet early onset escherichia coli that enterotoxigenic Escherichia coli causes, it is suckling pig common disease, there is higher M & M, the serious development that hinders pig industry, piglet morbidity is rear as controlled and treatment not in time, will cause the full nest death of piglet, cause serious economic loss to raiser, and hinder the development of animal husbandry.

Can well treat at present the colibacillary medicine of piglet early onset and have chloromycetin, furazolidone, neomycin, sulfadiazine etc., but because furazolidone belongs to furans, furazolidone and chloromycetin have been classified national fowl poultry kind prohibitive materials as, neomycin and sulfadiazine off-drug period are long, and Reusability easily produces Resistant strain and on Western medicine, is not yet effectively treated the colibacillary medicine of piglet early onset.And be used for the treatment of that the colibacillary Chinese medicine preparation of piglet early onset is as loose in four taste Herba Andrographis, the loose and plus-minus Xiaohuang granule of four yellow Zhili granules, poplar flower oral liquid, dysentery relieving etc., clinical all right for preventing, but controlled very poor during really for piglet early onset escherichia coli and mixed infection, curative effect is very not desirable.

The present invention utilizes domestic a large amount of Chinese herbal medicine resource, according to Chinese medical theory and piglet pathogenesis etiology, with reference to eighteen incompatible medicaments nineteen medicaments of mutual restraint, the one of rationally utilizing the meridian distribution of property and flavor of Chinese herbal medicine and function to cure mainly development is treated colibacillary herbal medicine of piglet early onset and preparation method thereof, this product is pure Chinese medicinal preparation, good to the bacterial strain therapeutic effect of suffering from the colibacillary piglet of early onset and serious mixed infection or developed immunity to drugs, and antenatal sow is by feeding or feeding all can improve resistance and the anti-disease ability of anti-stress of piglet in sow and body, feeding sow in lactation also can be absorbed by piglet by milk, play the colibacillary effect of early treatment piglet early onset.This invention medicine is Chinese medicine solid powder, also can make an addition in feedstuff, have dosage accurately, steady quality, transport, store, carry, apply all more convenient; Mechanization production, output is large, and cost is low, and sanitary standard also easily reaches.

Summary of the invention

The object of the invention is to overcome the deficiency of existing preparation and technology, propose that a kind of safety, green, no drug residue, compatibility are reasonable, convenient drug administration, the simple one of technique treat colibacillary herbal medicine of piglet early onset and preparation method thereof.

The technical scheme that the present invention realizes object is;

Strengthen a Chinese medicine composition for piglet anti-infectious immunity function, form component and mass fraction thereof and be respectively:

Herba Houttuyniae 5-10 part; Cortex Phellodendri 5-10 part; Radix Isatidis 5-10 part; Cortex Fraxini 5-15 part; Polygonum viviparum L. 5-15 part; Rhizoma Coptidis 5-15 part; Radix Astragali 10-20 part; Radix Angelicae Sinensis 10-20 part; Pulvis Cornus Bubali Concentratus 3-5 part; Herba Violae 10-20 part; Radix Glycyrrhizae 3-5 part.

Can add one or more in Radix et Rhizoma Thalictri, Fructus Terminaliae Billericae, Rhizoma Polygoni Cuspidati, Herba Potentillae Discoloris.

A kind of Chinese medicine composition that strengthens piglet anti-infectious immunity function and preparation method thereof, step is:

(1) by Herba Houttuyniae, Cortex Phellodendri, Radix Isatidis, Cortex Fraxini, Polygonum viviparum L., Rhizoma Coptidis, the Radix Astragali, Radix Angelicae Sinensis, Pulvis Cornus Bubali Concentratus, Herba Violae, Radix Glycyrrhizae.Adopt Chinese medicine grinder to pulverize separately, cross respectively 80 mesh standard sieves, obtain Chinese crude drug fine powder;

(2) take the Pulvis Cornus Bubali Concentratus of recipe quantity for subsequent use;

(3) take (1) by prescription, mix 20 minutes;

(4) (2) are dropped in (3) and mixed 20 minutes, obtain a kind of colibacillary herbal medicine of piglet early onset for the treatment of.

And described Pulvis Cornus Bubali Concentratus does not need to pulverize, after needing to adopt, add mixing method.

Advantage of the present invention and beneficial effect are:

1, the present invention has innovated the colibacillary Chinese herbal medicine compatibility agent of control piglet early onset, fully demonstrate the advantage in the Chinese herbal medicine application of Chinese medicine big country, the important breakthrough of domestic new product application technology, for new Chinese prescription has been opened up in the colibacillary treatment of domestic piglet early onset.

2, the present invention has improved the first traditional treatment mode of controlling after being ill, can be by the antenatal feeding of sow to improve sow and piglet self immunity of organisms and resistance, also can absorb and utilize by milk, make piglet play early treatment's object, thereby reach prevention effect.

3, the technique the present invention relates to has that production equipment is simple, processing ease, advantage easy to use, to be applicable to industrialization, make up the blank of anti-piglet early onset escherichia coli treatment aspect, domestic veterinary drug market, innovated the Chinese prescription of reasonable compatibility, promoted the development of aquaculture.

Detailed description of the invention

Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.

Herba Houttuyniae 5-10 part; Cortex Phellodendri 5-10 part; Radix Isatidis 5-10 part; Cortex Fraxini 5-15 part; Polygonum viviparum L. 5-15 part; Rhizoma Coptidis 5-15 part; Radix Astragali 10-20 part; Radix Angelicae Sinensis 10-20 part; Pulvis Cornus Bubali Concentratus 3-5 part; Herba Violae 10-20 part; Radix Glycyrrhizae 3-5 part.

Can add one or more in Radix et Rhizoma Thalictri, Fructus Terminaliae Billericae, Rhizoma Polygoni Cuspidati, Herba Potentillae Discoloris.

Embodiment 1:

Strengthen a Chinese medicine composition for piglet anti-infectious immunity function, it forms component and parts by weight are respectively (following examples are same):

5 parts of Herba Houttuyniae; Cortex Phellodendri 5; Radix Isatidis 5; 5 parts of Cortex Fraxinis; 5 parts of Polygonum viviparum L.; 5 parts of Rhizoma Coptidis; 10 parts of the Radixs Astragali; 10 parts of Radix Angelicae Sinensis; 3 parts of Pulvis Cornus Bubali Concentratuss; 10 parts of Herba Violaes; 3 parts, Radix Glycyrrhizae.

Crude drug involved in the present invention all adopts the regulation of " Chinese veterinary pharmacopoeia " two Chinese crude drugs of in 2010 version and decoction pieces.

A kind of Chinese medicine composition that strengthens piglet anti-infectious immunity function and preparation method thereof, comprises the steps:

(1) by Herba Houttuyniae, Cortex Phellodendri, Radix Isatidis, Cortex Fraxini, Polygonum viviparum L., Rhizoma Coptidis, the Radix Astragali, Radix Angelicae Sinensis, Pulvis Cornus Bubali Concentratus, Herba Violae, Radix Glycyrrhizae.Adopt Chinese medicine grinder to pulverize separately, cross respectively 80 mesh standard sieves, obtain Chinese crude drug fine powder;

(2) take the Pulvis Cornus Bubali Concentratus of recipe quantity for subsequent use;

(3) take (1) by prescription, mix 20 minutes;

(4) (2) are dropped in (3) and mixed 20 minutes, obtain a kind of colibacillary herbal medicine of piglet early onset for the treatment of.

Embodiment 2:

Strengthen a Chinese medicine composition for piglet anti-infectious immunity function, it forms component and parts by weight are respectively:

10 parts of Herba Houttuyniae; 10 parts of Cortex Phellodendris; 10 parts of Radix Isatidis; 15 parts of Cortex Fraxinis; 15 parts of Polygonum viviparum L.; 15 parts of Rhizoma Coptidis; 20 parts of the Radixs Astragali; 20 parts of Radix Angelicae Sinensis; 5 parts of Pulvis Cornus Bubali Concentratuss; 20 parts of Herba Violaes; 5 parts, Radix Glycyrrhizae.

The step of the present embodiment preparation method is same as embodiment 1.

Detecting data: this invention is 100% for piglet early onset escherichia coli prevention effective percentage, is 98.6% for piglet early onset escherichia coli treatment obvious effective rate.

Claims (3)

1. one kind strengthens Chinese medicine composition of piglet anti-infectious immunity function and preparation method thereof, it is characterized in that: form component and mass fraction thereof and be respectively:

Herba Houttuyniae 5-10 part; Cortex Phellodendri 5-10 part; Radix Isatidis 5-10 part; Cortex Fraxini 5-15 part; Polygonum viviparum L. 5-15 part; Rhizoma Coptidis 5-15 part; Radix Astragali 10-20 part; Radix Angelicae Sinensis 10-20 part; Pulvis Cornus Bubali Concentratus 3-5 part; Herba Violae 10-20 part; Radix Glycyrrhizae 3-5 part.

2. a kind of Chinese medicine composition that strengthens piglet anti-infectious immunity function according to claim 1 and preparation method thereof, is characterized in that: describedly add one or more in Radix et Rhizoma Thalictri, Fructus Terminaliae Billericae, Rhizoma Polygoni Cuspidati, Herba Potentillae Discoloris.

3. one kind strengthens Chinese medicine composition of piglet anti-infectious immunity function and preparation method thereof, it is characterized in that: the step of preparation is:

(1) by Herba Houttuyniae, Cortex Phellodendri, Radix Isatidis, Cortex Fraxini, Polygonum viviparum L., Rhizoma Coptidis, the Radix Astragali, Radix Angelicae Sinensis, Pulvis Cornus Bubali Concentratus, Herba Violae, Radix Glycyrrhizae.Adopt Chinese medicine grinder to pulverize separately, cross respectively 80 mesh standard sieves, obtain Chinese crude drug fine powder;

(2) take the Pulvis Cornus Bubali Concentratus of recipe quantity for subsequent use;

(3) take each Chinese crude drug fine powder in (1) by prescription, mix 20 minutes;

(4) (2) are dropped in (3) and mixed 20 minutes, obtain a kind of colibacillary herbal medicine of piglet early onset for the treatment of.