CN103768330A - Traditional Chinese medicine composition for treating pullorum disease and preparation method of traditional Chinese medicine composition - Google Patents

Traditional Chinese medicine composition for treating pullorum disease and preparation method of traditional Chinese medicine composition Download PDF

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Publication number
CN103768330A
CN103768330A CN201210413430.7A CN201210413430A CN103768330A CN 103768330 A CN103768330 A CN 103768330A CN 201210413430 A CN201210413430 A CN 201210413430A CN 103768330 A CN103768330 A CN 103768330A
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parts
chinese medicine
medicine composition
radix
pullorum disease
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陈庆忠
安同伟
卢宪杰
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TIANJIN ZHONGGAO BIOTECHNOLOGY CO Ltd
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TIANJIN ZHONGGAO BIOTECHNOLOGY CO Ltd
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Abstract

The invention relates to a traditional Chinese medicine composition for treating pullorum disease. The traditional Chinese medicine composition comprises the following components by weight: 15 to 30 parts of scutellaria baicalensis, 15 to 25 parts of Chinese pulsatilla root, 20 to 30 parts of berberis julianae schneid, 15 to 25 parts of rhizoma alismatis, 10 to 20 parts of honeysuckle, 10 to 20 parts of dandelion, 10 to 20 parts of hawthorn, 10 to 20 parts of medicated leaven and 15 to 25 parts of Chinese yam. The traditional Chinese medicine composition comprises effective constituents for clearing heat, detoxifying, tonifying spleen and stopping dysentery, has excellent functions of treating the pullorum disease of a chicken, a bred chicken or an adult chicken, has no medicine residue, and is convenient to use and lower in cost.

Description

Chinese medicine composition for the treatment of Pullorum Disease and preparation method thereof
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition for the treatment of Pullorum Disease and preparation method thereof.
Background technology
Nowadays people increase gradually to the demand of birds, and China's poultry husbandry development grows, and use because antibiotic, hormone etc. are frequent, cause the drug resistance of drug effect decline, chicken to strengthen.Traditional Chinese herbal medicine, Western medicine etc. all can not effectively be treated Pullorum Disease, and to chickling, be bred as chicken, Adult Chicken and use different medicines, increase residual in fowl body of medicine, increase the toxic and side effects to the mankind, slow down the development of China's poultry husbandry.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of Pullorum Disease, this Chinese medicine composition has good treatment chickling, is bred as chicken, the effect of Adult Chicken Hakuri, and drug residue can not occur, and easy to use, cost is lower.
Another object of the present invention is to provide a kind of preparation method of Chinese medicine composition for the treatment of Pullorum Disease.
The present invention is achieved by the following technical solutions:
Treat a Chinese medicine composition for Pullorum Disease, component and the ratio of weight and number thereof of its Chinese medicine composition are respectively:
Radix Scutellariae 15-30 part;
Radix Pulsatillae 15-25 part;
Radix Berberidis 20-30 part;
Flos Lonicerae 10-20 part;
Herba Taraxaci 10-20 part;
Rhizoma Alismatis 15-25 part;
Fructus Crataegi 10-20 part;
Massa Medicata Fermentata 10-20 part;
Rhizoma Dioscoreae 15-25 part.
And this Chinese medicine composition component and optimum ratio of weight and number thereof are respectively:
25 parts of Radix Scutellariaes;
20 parts of the Radix Pulsatillaes;
25 parts of Radix Berberidis;
17 parts of Flos Loniceraes;
15 parts of Herba Taraxacis;
20 parts of Rhizoma Alismatis;
15 parts of Fructus Crataegis;
15 parts of Massa Medicata Fermentatas;
20 parts of Rhizoma Dioscoreaes.
Treat a preparation method for the Chinese medicine composition of Pullorum Disease, its step is as follows:
(1) take respectively Radix Scutellariae, the Radix Pulsatillae, Radix Berberidis, Flos Lonicerae, Herba Taraxaci, Rhizoma Alismatis, Fructus Crataegi, Massa Medicata Fermentata, Rhizoma Dioscoreae according to weight proportion and pulverize, and respectively all by 80 mesh sieves;
(2) Radix Scutellariae after sieving, the Radix Pulsatillae, Radix Berberidis, Flos Lonicerae, Herba Taraxaci, Rhizoma Alismatis, Fructus Crataegi, Massa Medicata Fermentata, Rhizoma Dioscoreae are put into abundant mix homogeneously in blending tank, the Chinese medicine composition finished product of the Pullorum Disease that both obtained medical treatment.
Advantage of the present invention and beneficial effect are:
1, the Chinese medicine composition of this treatment Pullorum Disease contains Radix Scutellariae, the Radix Pulsatillae, Radix Berberidis, Flos Lonicerae, Herba Taraxaci, Rhizoma Alismatis, Fructus Crataegi, Massa Medicata Fermentata, Rhizoma Dioscoreae, and can Qinghua damp and hot, heat-clearing and toxic substances removing have the effects such as treatment Pullorum Disease, spleen reinforcing weightening finish.
2, the Chinese medicine composition broad-spectrum high efficacy of this treatment Pullorum Disease, to gastric acid quite stable, rear absorption well for oral administration, is not affected by water temperature, acid-base value, just can reach blood peak concentration of drug simultaneously at extremely low concentration and in the short period.
3, the present invention contains heat-clearing and toxic substances removing, and the effective ingredient of spleen invigorating dysentery relieving has the effect of fine treatment Pullorum Disease, and drug residue can not occur, and easy to use, cost is lower.
The specific embodiment
The present invention is described in further detail by following examples.It should be noted that: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
In component involved in the present invention, Radix Scutellariae, the Radix Pulsatillae, Radix Berberidis, Flos Lonicerae, Herba Taraxaci, Rhizoma Alismatis, Fructus Crataegi, Massa Medicata Fermentata, Rhizoma Dioscoreae all can be bought and obtain on market.
Embodiment 1
Treat a Chinese medicine composition for Pullorum Disease, component and the weight thereof of its Chinese medicine composition are respectively: Radix Scutellariae 20g, Radix Pulsatillae 16g, Radix Berberidis 20g, Flos Lonicerae 14g, Herba Taraxaci 12g, Rhizoma Alismatis 15g, Fructus Crataegi 10g, Massa Medicata Fermentata 10g, Rhizoma Dioscoreae 15g.
Treat a preparation method for the Chinese medicine composition of Pullorum Disease, the step of its preparation method is as follows:
(1) take respectively Radix Scutellariae, the Radix Pulsatillae, Radix Berberidis, Flos Lonicerae, Herba Taraxaci, Rhizoma Alismatis, Fructus Crataegi, Massa Medicata Fermentata, Rhizoma Dioscoreae according to weight proportion and pulverize, and respectively all by 80 mesh sieves;
(2) Radix Scutellariae after sieving, the Radix Pulsatillae, Radix Berberidis, Flos Lonicerae, Herba Taraxaci, Rhizoma Alismatis, Fructus Crataegi, Massa Medicata Fermentata, Rhizoma Dioscoreae are put into abundant mix homogeneously in blending tank, the Chinese medicine composition finished product of the Pullorum Disease that both obtained medical treatment.
Embodiment 2
Treat a Chinese medicine composition for Pullorum Disease, component and the weight thereof of its Chinese medicine composition are respectively: Radix Scutellariae 25g, Radix Pulsatillae 20g, Radix Berberidis 25g, Flos Lonicerae 17g, Herba Taraxaci 15g, Rhizoma Alismatis 20g, Fructus Crataegi 15g, Massa Medicata Fermentata 15g, Rhizoma Dioscoreae 20g.
The step of its preparation method is with embodiment 1.
Embodiment 3
Treat a Chinese medicine composition for Pullorum Disease, component and the weight thereof of its Chinese medicine composition are respectively: Radix Scutellariae 30g, Radix Pulsatillae 25g, Radix Berberidis 30g, Flos Lonicerae 20g, Herba Taraxaci 20g, Rhizoma Alismatis 25g, Fructus Crataegi 20g, Massa Medicata Fermentata 20g, Rhizoma Dioscoreae 25g.
The step of its preparation method is with embodiment 1.
Using method of the present invention, chickling is boiled by the amount of the 8-15g 1000ml that adds water, and gets supernatant liquid for oral administration, and sooner or later respectively once, can reach therapeutic effect in 2-3 days every day.Be bred as chicken and Adult Chicken and only press 2-3g/, after mixing homogeneously, feed with feedstuff, sooner or later respectively once, can reach therapeutic effect in 2-3 days every day.
Clinical trial
Use advantage of the present invention below by concrete test explanation:
The Hakuri of 1 primary treatment chickling of the present invention, incubation chicken and Adult Chicken.Pullorum Disease, also can be by vertical transmission to filial generation mainly by transmission.The chicken of infected chicken Hakuri all there will be lassitude, appetite decline, feces to have the pathological characters such as abnormal flavour.The present invention carries out dysentery relieving detoxification experiment to being bred as chicken:
1.1 get 60 ages in days, body weight is bred as 240 of chickens uniformly, is divided at random 4 groups, 60 every group.Be test group of the present invention, oxytetracycline group, the Radix Pulsatillae group of faling apart, blank group, is designated as respectively A group, B group, C group, D group.
1.2 by the feedstuff with a certain amount of Pullorum Disease Salmonella, feeds to 4 groups 240 healthy incubation chickens, and feeding is all bred as chicken for 2-3 days and all occurs Pullorum Disease phenomenon.Be bred as chickens by 240 of infected chicken Hakuri and be divided into 4 groups, raise respectively in conditions such as ventilation, temperature, water source, raisings all in identical Factory Building isolation mutually, control cross infection.The cleaning of having abundant water resources, food abundance, feeds 3 every day.
After 1.3 incubation chicken morbidities, test immediately.Test group of the present invention is fed to being bred as chicken by every chicken 2-3g, and every day sooner or later respectively once; Oxytetracycline group is fed to experimental chicken by every chicken 2-3g, every day 2 times, sooner or later respectively once; Every chicken 2-3g of the loose group of the Radix Pulsatillae feeds to experimental chicken, every day 2 times, sooner or later respectively once; Blank group does not give any medicine.Continuous Observation 30 days, does once record in every three days, and by outcome record in following table.
Pullorum Disease situation
Figure BSA00000794955100041
As can be seen from the above table test group of the present invention to the incubation chicken therapeutic effect of Hakuri is better, the incubation chicken having more than 50% for about a week after medication does not have dysentery phenomenon.Along with the prolongation of time, be bred as Pullorum Disease situation and take a turn for the better gradually, about 20 days, only have 9 incubation chickens to have dysentery phenomenon, finally only have 1 death, account for 1.67% of sum.
Oxytetracycline group has certain curative effect to being bred as Pullorum Disease treatment, and after medication, there is a change for the better for chicken dysentery, but resume speed is slower.Within after medication about one week, there is 28% incubation chicken successfully to cure.Along with administration time extends, there is a change for the better for dysentery, but cure rate is lower, finally has 9 to be bred as chicken death, accounts for 15% of sum.
The loose group of the Radix Pulsatillae is general to being bred as Pullorum Disease therapeutic effect, within after medication about one week, has 35% incubation chicken to get well, and be then bred as chicken dysentery and take a turn for the better to some extent, but therapeutic effect is not good, finally has 11 incubation chicken deaths, accounts for total 18.33%.
The incubation chicken of blank group does not give any medicine, has just started Pullorum Disease and has not almost taken a turn for the better, and after even Hakuri occurs one week, has the chicken death of incubation phenomenon.Along with being bred as the prolongation of fowl raising time, the immunity of chicken and corresponding resistance also obviously increase, so Hakuri phenomenon takes a turn for the better to some extent.But mortality rate is higher, finally there are 21 death, account for 35% of sum.
As can be seen from the above table, Pullorum Disease can cause chicken lassitude, appetite depression, feces whiting and have abnormal flavour.The therapeutic effect of test group of the present invention is obviously better than oxytetracycline group and the loose group of the Radix Pulsatillae, and test group of the present invention obviously increases the immunity of chicken, promotes appetite, reduces the mortality rate that chicken causes due to dysentery.The mortality rate of blank group is the highest, is 35%, and visible Pullorum Disease mortality rate is higher, and test group of the present invention can better be cured Pullorum Disease.
2 malicious secondary result of the tests: during field test, participate in the experiment the physical signs such as the body temperature, breathing, pulse of chicken all within normal range, the mental status is normal, energy is strong, honey stomach, feces urine are observed without ANOMALOUS VARIATIONS, and none death, also without any untoward reaction.Show that the present invention has no side effect to chicken.

Claims (3)

1. a Chinese medicine composition for the treatment of Pullorum Disease, is characterized in that: component and the ratio of weight and number thereof of this Chinese medicine composition are respectively:
Radix Scutellariae 15-30 part;
Radix Pulsatillae 15-25 part;
Radix Berberidis 20-30 part;
Flos Lonicerae 10-20 part;
Herba Taraxaci 10-20 part;
Rhizoma Alismatis 15-25 part;
Fructus Crataegi 10-20 part;
Massa Medicata Fermentata 10-20 part;
Rhizoma Dioscoreae 15-25 part.
2. the Chinese medicine composition for the treatment of Pullorum Disease according to claim 1, is characterized in that: the component of this Chinese medicine composition and optimum ratio of weight and number thereof are:
25 parts of Radix Scutellariaes;
20 parts of the Radix Pulsatillaes;
25 parts of Radix Berberidis;
17 parts of Flos Loniceraes;
15 parts of Herba Taraxacis;
20 parts of Rhizoma Alismatis;
15 parts of Fructus Crataegis;
15 parts of Massa Medicata Fermentatas;
20 parts of Rhizoma Dioscoreaes.
3. a preparation method for the Chinese medicine composition for the treatment of Pullorum Disease as claimed in claim 1, is characterized in that: the step of this preparation method is as follows:
(1) take respectively Radix Scutellariae, the Radix Pulsatillae, Radix Berberidis, Flos Lonicerae, Herba Taraxaci, Rhizoma Alismatis, Fructus Crataegi, Massa Medicata Fermentata, Rhizoma Dioscoreae according to weight proportion and pulverize, and respectively all by 80 mesh sieves;
(2) Radix Scutellariae after sieving, the Radix Pulsatillae, Radix Berberidis, Flos Lonicerae, Herba Taraxaci, Rhizoma Alismatis, Fructus Crataegi, Massa Medicata Fermentata, Rhizoma Dioscoreae are put into abundant mix homogeneously in blending tank, the Chinese medicine composition finished product of the Pullorum Disease that both obtained medical treatment.
CN201210413430.7A 2012-10-24 2012-10-24 Traditional Chinese medicine composition for treating pullorum disease and preparation method of traditional Chinese medicine composition Pending CN103768330A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105250424A (en) * 2015-11-15 2016-01-20 衡阳市金凤牲猪养殖专业合作社 Drug for preventing and treating pullorum disease and preparation method thereof
CN105494950A (en) * 2015-12-23 2016-04-20 铜陵润生生态养殖有限公司 Chicken feed additive for preventing avian staphylocosis and pullorum disease
CN106177472A (en) * 2016-08-29 2016-12-07 高亮 A kind of Chinese medicine composition treating Pullorum Disease

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1286999A (en) * 1999-09-03 2001-03-14 周来云 Veterinary medicine
CN102028907A (en) * 2009-09-29 2011-04-27 赵宪梅 Traditional Chinese medicinal preparation for treating yellow scour of newborn piglets

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1286999A (en) * 1999-09-03 2001-03-14 周来云 Veterinary medicine
CN102028907A (en) * 2009-09-29 2011-04-27 赵宪梅 Traditional Chinese medicinal preparation for treating yellow scour of newborn piglets

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105250424A (en) * 2015-11-15 2016-01-20 衡阳市金凤牲猪养殖专业合作社 Drug for preventing and treating pullorum disease and preparation method thereof
CN105494950A (en) * 2015-12-23 2016-04-20 铜陵润生生态养殖有限公司 Chicken feed additive for preventing avian staphylocosis and pullorum disease
CN106177472A (en) * 2016-08-29 2016-12-07 高亮 A kind of Chinese medicine composition treating Pullorum Disease

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Application publication date: 20140507