CN104256182A - Feed additive with fermented Chinese herbal medicine for treating dairy cow hemafecia - Google Patents

Feed additive with fermented Chinese herbal medicine for treating dairy cow hemafecia Download PDF

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Publication number
CN104256182A
CN104256182A CN201410527876.1A CN201410527876A CN104256182A CN 104256182 A CN104256182 A CN 104256182A CN 201410527876 A CN201410527876 A CN 201410527876A CN 104256182 A CN104256182 A CN 104256182A
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chinese herbal
fermentation
herbal medicine
feed additive
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CN201410527876.1A
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董书阁
董立波
侯文燕
董静静
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Qingdao Jiarui Biological Technology Co Ltd
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Qingdao Jiarui Biological Technology Co Ltd
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Abstract

The invention discloses a feed additive used for treating dairy cow hemafecia, which takes a Chinese herbal medicine fermentation product as a main component. The feed additive is characterized by comprising the fermented Chinese herbal medicine, herba schizonepetae carbonisatum, colla corii asini, an amino acid trace element chelating agent, carbonized sanguisorba root and furnace soil, wherein the fermented Chinese herbal medicine is prepared by angelica sinensis, semen ziziphi spinosae, red paeony root, coptidis rhizoma, polygala tenuifolia, lonicera japonica, fructus forsythiae, cape jasmine, liquorice, atractylodes macrocephala, radix scutellariae, myrobalan and fried cacumen biotae through a process comprising the ultrasonic assisted degradation and mixed fermentation. The feed additive has the advantages that the production process comprising the ultrasonic assisted degradation and mixed fermentation is adopted, the effects are more remarkable than those of an existing Chinese herbal medicine feed additive, and the dairy cow hemafecia caused by cold-dampness, heat toxin and other reasons can be effectively treated; the feed additive has the advantages of quick effects, definite treatment effects, less possibility of the occurrence of drug resistance, small side effects, low animal product drug residue amount and capability of improvig human and animal safety in aspect of treating the hemafecia.

Description

A kind of fermentation of Chinese herbal medicine feed addictive for the treatment of milk cow and having blood in stool
Technical field
The present invention relates to a kind of fermentation of Chinese herbal medicine feed addictive for the treatment of milk cow and having blood in stool, belong to feed additive field.
Background technology
Milk cow production is the farming industry of economical and efficient, is one of important component part of agricultural modernization.Nowadays the development of milk industry is all paid much attention in countries in the world.The milk industry output value of developed country generally accounts for about 1/3 of the animal husbandry gross output value.Milk is already through becoming the pillar industry of developed country's agricultural, and they see the important symbol of the agricultural modernization especially flourishing level of animal husbandry as the development degree of milk industry.Milk crop and occupancy volume per person have been regarded as one of leading indicator of national economy development degree and overall national strength power.The milk cow production of current China presents sustainable growth situation always, and within 2013, China's cow population reaches 1,500 ten thousand, becomes the important component part of China's agricultural economy.
Diarrhoea is one of modal disease in milk cattle cultivating, its pathogenic factor mainly contain feeding and management improper, drink feed do not save, forced labour excessively or usually has a delicate constitution or cold-dampness, damp and hot in invade caused by, bring serious adverse effect to milk cattle cultivating.In the treatment of current diarrhea of dairy cow, adopt Western medicine more, but Western medicine particularly antibiotic therapy easily produces drug resistance, suppresses stomach and intestine beneficial microbes, upsets balance between rumen microbial population, upsets Rumen Internal Environment, causes the side effects such as the indigestion of serious suprainfection and stubbornness, have that livestock products drug residue amount is high, the shortcoming such as threaten human food safely simultaneously.In clinical practice, also often see due to a large amount of Long-Time Service antibiotic, particularly antibiotic for oral administration, causes serious indigestion and rumen peristalsis to weaken and even stops, and appetite, ruminates completely absolutely useless, is difficult to the case of rehabilitation again.Having blood in stool is modal one in diarrhoea.
China is vast in territory, and Chinese herbal medicine resource is very abundant, therefore in development Chinese herb feed additive, has huge potentiality.The research level of current Chinese herbal feed additive is lower, manufacture craft simple coarse, and the technological element of a product is lower, and quality is stable not, and problem like this seriously governs applying of Chinese medicine fodder interpolation.Fermentable Chinese medicine is reform to traditional Chinese medicine process technology and innovation, has various features and advantage.This technology is introduced the research of Chinese herbal feed additive, its scientific and technological content can be made significantly to promote, effect is more remarkable, quality is more stable, benefit is more obvious, can immunity of organisms be significantly improved, strengthen the level of milk cow resist the disease, have important using value for the various problems solving current milk cattle cultivating.
Summary of the invention
The advantage a kind of feed addictive being main component with Chinese herbal medicine tunning being used for the treatment of milk cow and having blood in stool is provided during technical problem to be solved by this invention, the milk cow adopting this feed addictive to feed has instant effect in treatment is had blood in stool, curative effect develops immunity to drugs really, not easily, side effect is little, livestock products drug residue is low, being conducive to person poultry safety.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The invention provides a kind of fermentation of Chinese herbal medicine feed addictive for the treatment of milk cow and having blood in stool, it is characterized in that being made up of the component of following mass ratio: fermentation of Chinese herbal medicine 60 ~ 70 parts, charred schizonepeta 4 ~ 6 parts, 8 ~ 12 parts, donkey-hide gelatin, amino acid trace element chelated dose 8 ~ 12 parts, charred RADIX SANGUISORBAE 4 ~ 6 parts, humus flava usta 4 ~ 6 parts.
Above-mentioned fermentation of Chinese herbal medicine mixture is obtained by compound Chinese herb " ultrasonic assistant degraded+mixed fungus fermentation " technique.
Described compound Chinese herb, is characterized in that being made up of the Chinese herbal medicine of following mass ratio: Radix Angelicae Sinensis 12 ~ 18 parts, spina date seed 8 ~ 12 parts, the radix paeoniae rubrathe 8 ~ 12 parts, the coptis 6 ~ 10 parts, polygala root 3 ~ 5 parts, honeysuckle 6 ~ 10 parts, the capsule of weeping forsythia 6 ~ 8 parts, cape jasmine 3 ~ 5 parts, 6 ~ 10 parts, Radix Glycyrrhizae, the bighead atractylodes rhizome 6 ~ 10 parts, the root of large-flowered skullcap 6 ~ 10 parts, myrobalan 3 ~ 5 parts, stir-fry cacumen biotae 3 ~ 5 parts.
Described probio comprises bafillus natto, saccharomyces cerevisiae, bacillus subtilis, bifidobacterium bifidum.
To the invention provides kind a treatment milk cow to have blood in stool fermentation of Chinese herbal medicine feed addictive, it is characterized in that specifically comprising the following steps:
(1) preparation of compound Chinese herb: according to above-mentioned formula precise Chinese herbal medicine, be crushed to 40 ~ 60 orders, mix, obtained compound Chinese herb;
(2) ultrasonic assistant degraded: the water adding 5 ~ 10 times in compound Chinese herb pulvis, under ultrasonic assistant effect, reflux under 100 DEG C of conditions degraded 20 ~ 30min;
(3) zymotic fluid preparation: add 5.0 ~ 8.0% glucose, 2.0 ~ 3.0% yeast extracts, 0.3 ~ 0.5% potassium dihydrogen phosphate, 0.02%MgSO in the Chinese herbal medicine degradation solution after degraded 4.7H 2o, 0.01%CaCl 2, pH is adjusted to 7.0 ~ 7.2;
(4) mixed fungus fermentation: select liquid fermentation tank, liquid amount is 60 ~ 70%, bafillus natto after inoculation activation, saccharomyces cerevisiae, bacillus subtilis, inoculum concentration is respectively 2 ~ 4%, 5 ~ 8%, 2 ~ 4%, control fermentation temperature 28 ~ 37 DEG C, rotating speed 150 ~ 300rpm, throughput 10 ~ 20L/min; At this fermentation condition bottom fermentation 12 ~ 24h; Then the bifidobacterium bifidum after inoculation activation, inoculum concentration 3 ~ 5%, standing for fermentation 12h;
(5) adsorption dry: after having fermented, fermented liquid 1.2 ~ 2 volume ratio wheat brans are adsorbed, dry in 40 ~ 60 DEG C of blast driers, moisture controls 8 ~ 10%;
(6) pulverize: pulverizing of being sieved by dried product pulverizer 60 order, obtains fermentation of Chinese herbal medicine mixture;
(7) mix: by fermentation of Chinese herbal medicine, charred schizonepeta, donkey-hide gelatin, amino acid trace element chelated dose, charred RADIX SANGUISORBAE, humus flava usta mix in proportion;
(8) crushing packing: namely mixture crushing packing is obtained Chinese herbal feed additive.
To the invention provides kind a treatment milk cow to have blood in stool fermentation of Chinese herbal medicine feed addictive, the mass ratio that described fermented type Chinese herb medicine additive for milk cow forage product uses in milk cow has blood in stool daily ration is 1 ~ 2%.
The present invention, according to the growth characteristic of the phase milk cow that gives milk and growth characteristic, have chosen multiple medicinal herb components and nutritional cost combines, and improves by the fermentation of probio the effect that additive treatment milk cow has blood in stool.Selected Chinese herbal medicine is natural, safe Chinese herbal medicine, the configuration criteria of " monarch " is strictly followed in its process for preparation, the optimum amount of Chinese herbal medicine is finally determined through repetition test and checking, make Synergistic between various medicinal herb components, mutually promote and reach the effect that fabulous treatment milk cow has blood in stool; This invention product is the soft multiple additives with the treatment effect of having blood in stool on the basis of fermentation of Chinese herbal medicine also, further increases the effect that treatment milk cow is had blood in stool.Culture experiment result shows that test group milk cow (n=30) to be had blood in stool phenomenon for there is milk cow under the condition of initiatively not preventing epidemic, control group then has 4 routine milk cows to have blood in stool phenomenon (p<0.05), shows effect that product of the present invention has prevention milk cow preferably and has blood in stool.
To the invention provides kind a treatment milk cow to have blood in stool fermentation of Chinese herbal medicine feed addictive, it is advantageous that: one is the production technology that have employed " Chinese herbal medicine ultrasonic assistant degraded+mixed fungus fermentation " in fermentation of Chinese herbal medicine feed addictive preparation process, and action effect is more remarkable compared with existing Chinese herbal feed additive product; Two is two-fold advantage that fermentation of Chinese herbal medicine feed addictive has Chinese herbal medicine and probio, effectively can treat milk cow because of having blood in stool of causing of reason such as cold-dampness, cold-dampness, heat poison; Three is this Product Green safety, has no adverse effects, there is not the problem such as medicament residue and drug resistance to milk cow.
Detailed description of the invention
embodiment 1:
One is treated milk cow and to be had blood in stool fermentation of Chinese herbal medicine feed addictive, and concrete preparation process is as follows:
(1) weigh: according to following formula precise Chinese herbal medicine: Radix Angelicae Sinensis 12 parts, spina date seed 12 parts, the radix paeoniae rubrathe 8 parts, the coptis 10 parts, polygala root 3 parts, honeysuckle 10 parts, the capsule of weeping forsythia 6 parts, cape jasmine 5 parts, 6 parts, Radix Glycyrrhizae, the bighead atractylodes rhizome 10 parts, the root of large-flowered skullcap 6 parts, myrobalan 3 parts, stir-fry cacumen biotae 3 parts;
(2) preparation of compound Chinese herb: the Chinese herbal medicine powder after weighing is broken to 40 ~ 60 orders, mixes, obtained compound Chinese herb;
(3) ultrasonic assistant degraded: the water adding 5 times in compound Chinese herb pulvis, under ultrasonic assistant effect, reflux under 100 DEG C of conditions degraded 20 ~ 30min;
(4) zymotic fluid preparation: add 5.0% glucose, 2.0% yeast extract, 0.3% potassium dihydrogen phosphate, 0.02%MgSO in the Chinese herbal medicine degradation solution after degraded 4.7H 2o, 0.01%CaCl 2, pH is adjusted to 7.0 ~ 7.2;
(5) mixed fungus fermentation: select liquid fermentation tank, liquid amount is 60 ~ 70%, the bafillus natto after inoculation activation, saccharomyces cerevisiae, bacillus subtilis, inoculum concentration is respectively 2%, 5%, 2%, control fermentation temperature 28 ~ 37 DEG C, rotating speed 150 ~ 300rpm, throughput 10 ~ 20L/min; At this fermentation condition bottom fermentation 24h; Then the bifidobacterium bifidum after inoculation activation, inoculum concentration 3%, standing for fermentation 12h;
(6) adsorption dry: after having fermented, fermented liquid 1.2 volume ratio wheat brans are adsorbed, dry in 40 ~ 60 DEG C of blast driers, moisture controls 8 ~ 10%;
(7) pulverize: pulverizing of being sieved by dried product pulverizer 60 order, obtains fermentation of Chinese herbal medicine mixture;
(8) mix: in fermentation of Chinese herbal medicine 65 parts, bifidobacterium bifidum 5 parts, glucoproteinase 10 parts, amino acid trace element chelated dose 10 parts, bacillus subtilis 5 parts, brewer's yeast 5 parts ratio mix;
(9) crushing packing: namely mixture crushing packing is obtained Chinese herbal feed additive.
embodiment 2:
One is treated milk cow and to be had blood in stool fermentation of Chinese herbal medicine feed addictive, and concrete preparation process is as follows:
(1) weigh: according to following formula precise Chinese herbal medicine: Radix Angelicae Sinensis 18 parts, spina date seed 8 parts, the radix paeoniae rubrathe 12 parts, the coptis 6 parts, polygala root 5 parts, honeysuckle 6 parts, the capsule of weeping forsythia 8 parts, cape jasmine 3 parts, 10 parts, Radix Glycyrrhizae, the bighead atractylodes rhizome 6 parts, the root of large-flowered skullcap 10 parts, myrobalan 5 parts, stir-fry cacumen biotae 4 parts;
(2) preparation of compound Chinese herb: the Chinese herbal medicine powder after weighing is broken to 40 ~ 60 orders, mixes, obtained compound Chinese herb;
(3) ultrasonic assistant degraded: the water adding 5 times in compound Chinese herb pulvis, under ultrasonic assistant effect, reflux under 100 DEG C of conditions degraded 20 ~ 30min;
(4) zymotic fluid preparation: add 8.0% glucose, 3.0% yeast extract, 0.5% potassium dihydrogen phosphate, 0.02%MgSO in the Chinese herbal medicine degradation solution after degraded 4.7H 2o, 0.01%CaCl 2, pH is adjusted to 7.0 ~ 7.2;
(5) mixed fungus fermentation: select liquid fermentation tank, liquid amount is 60 ~ 70%, the bafillus natto after inoculation activation, saccharomyces cerevisiae, bacillus subtilis, inoculum concentration is respectively 4%, 8%, 4%, control fermentation temperature 28 ~ 37 DEG C, rotating speed 150 ~ 300rpm, throughput 10 ~ 20L/min; At this fermentation condition bottom fermentation 12h; Then the bifidobacterium bifidum after inoculation activation, inoculum concentration 5%, standing for fermentation 12h;
(6) adsorption dry: after having fermented, fermented liquid 1.2 ~ 2 volume ratio wheat brans are adsorbed, dry in 40 ~ 60 DEG C of blast driers, moisture controls 8 ~ 10%;
(7) pulverize: pulverizing of being sieved by dried product pulverizer 60 order, obtains fermentation of Chinese herbal medicine mixture;
(8) mix: in fermentation of Chinese herbal medicine 60 parts, bifidobacterium bifidum 6 parts, glucoproteinase 12 parts, amino acid trace element chelated dose 12 parts, bacillus subtilis 4 parts, brewer's yeast 6 parts ratio mix;
(9) crushing packing: namely mixture crushing packing is obtained Chinese herbal feed additive.
embodiment 3:
One is treated milk cow and to be had blood in stool fermentation of Chinese herbal medicine feed addictive, and concrete preparation process is as follows:
(1) weigh: according to following formula precise Chinese herbal medicine: Radix Angelicae Sinensis 15 parts, spina date seed 10 parts, the radix paeoniae rubrathe 10 parts, the coptis 8 parts, polygala root 4 parts, honeysuckle 8 parts, the capsule of weeping forsythia 7 parts, cape jasmine 4 parts, 8 parts, Radix Glycyrrhizae, the bighead atractylodes rhizome 8 parts, the root of large-flowered skullcap 8 parts, myrobalan 4 parts, stir-fry cacumen biotae 5 parts;
(2) preparation of compound Chinese herb: the Chinese herbal medicine powder after weighing is broken to 40 ~ 60 orders, mixes, obtained compound Chinese herb;
(3) ultrasonic assistant degraded: the water adding 5 times in compound Chinese herb pulvis, under ultrasonic assistant effect, reflux under 100 DEG C of conditions degraded 20 ~ 30min;
(4) zymotic fluid preparation: add 7.0% glucose, 2.5% yeast extract, 0.4% potassium dihydrogen phosphate, 0.02%MgSO in the Chinese herbal medicine degradation solution after degraded 4.7H 2o, 0.01%CaCl 2, pH is adjusted to 7.0 ~ 7.2;
(5) mixed fungus fermentation: select liquid fermentation tank, liquid amount is 60 ~ 70%, the bafillus natto after inoculation activation, saccharomyces cerevisiae, bacillus subtilis, inoculum concentration is respectively 3%, 7%, 2 ~ 4%, control fermentation temperature 28 ~ 37 DEG C, rotating speed 150 ~ 300rpm, throughput 10 ~ 20L/min; At this fermentation condition bottom fermentation 18h; Then the bifidobacterium bifidum after inoculation activation, inoculum concentration 4%, standing for fermentation 12h;
(6) adsorption dry: after having fermented, fermented liquid 1.2 ~ 2 volume ratio wheat brans are adsorbed, dry in 40 ~ 60 DEG C of blast driers, moisture controls 8 ~ 10%;
(7) pulverize: pulverizing of being sieved by dried product pulverizer 60 order, obtains fermentation of Chinese herbal medicine mixture;
(8) mix: in fermentation of Chinese herbal medicine 70 parts, bifidobacterium bifidum 4 parts, glucoproteinase 8 parts, amino acid trace element chelated dose 8 parts, bacillus subtilis 6 parts, brewer's yeast 6 parts ratio mix;
(9) crushing packing: namely mixture crushing packing is obtained Chinese herbal feed additive.
Above embodiment only for illustration of technical scheme of the present invention, but not is limited; Although be described in detail by invention with reference to previous embodiment, for the person of ordinary skill of the art, still the technical scheme described in previous embodiment can be modified, or equivalent replacement has been carried out to wherein portion of techniques feature; And to these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of the present invention's technical scheme required for protection.

Claims (1)

1. treat the fermentation of Chinese herbal medicine feed addictive that milk cow is had blood in stool, it is characterized in that being prepared by following steps:
(1) preparation of compound Chinese herb: in Radix Angelicae Sinensis 12 ~ 18 parts, spina date seed 8 ~ 12 parts, the radix paeoniae rubrathe 8 ~ 12 parts, the coptis 6 ~ 10 parts, polygala root 3 ~ 5 parts, honeysuckle 6 ~ 10 parts, the capsule of weeping forsythia 6 ~ 8 parts, cape jasmine 3 ~ 5 parts, 6 ~ 10 parts, Radix Glycyrrhizae, the bighead atractylodes rhizome 6 ~ 10 parts, the root of large-flowered skullcap 6 ~ 10 parts, myrobalan 3 ~ 5 parts, fry cacumen biotae 3 ~ 5 parts of ratio precise Chinese herbal medicines, be crushed to 40 ~ 60 orders, mix, obtained compound Chinese herb;
(2) ultrasonic assistant degraded: the water adding 5 ~ 10 times in compound Chinese herb pulvis, under ultrasonic assistant effect, reflux under 100 DEG C of conditions degraded 20 ~ 30min;
(3) zymotic fluid preparation: add 5.0 ~ 8.0% glucose, 2.0 ~ 3.0% yeast extracts, 0.3 ~ 0.5% potassium dihydrogen phosphate, 0.02%MgSO in the Chinese herbal medicine degradation solution after degraded 4.7H 2o, 0.01%CaCl 2, pH is adjusted to 7.0 ~ 7.2;
(4) mixed fungus fermentation: select liquid fermentation tank, liquid amount is 60 ~ 70%, bafillus natto after inoculation activation, saccharomyces cerevisiae, bacillus subtilis, inoculum concentration is respectively 2 ~ 4%, 5 ~ 8%, 2 ~ 4%, control fermentation temperature 28 ~ 37 DEG C, rotating speed 150 ~ 300rpm, throughput 10 ~ 20L/min; At this fermentation condition bottom fermentation 12 ~ 24h; Then the bifidobacterium bifidum after inoculation activation, inoculum concentration 3 ~ 5%, standing for fermentation 12h;
(5) adsorption dry: after having fermented, fermented liquid 1.2 ~ 2 volume ratio wheat brans are adsorbed, dry in 40 ~ 60 DEG C of blast driers, moisture controls 8 ~ 10%;
(6) pulverize: pulverizing of being sieved by dried product pulverizer 60 order, obtains fermentation of Chinese herbal medicine mixture;
(7) mix: in fermentation of Chinese herbal medicine 60 ~ 70 parts, charred schizonepeta 4 ~ 6 parts, 8 ~ 12 parts, donkey-hide gelatin, amino acid trace element chelated dose 8 ~ 12 parts, charred RADIX SANGUISORBAE 4 ~ 6 parts, humus flava usta 4 ~ 6 parts of ratios mix;
(8) crushing packing: namely mixture crushing packing is obtained Chinese herbal feed additive.
CN201410527876.1A 2014-10-10 2014-10-10 Feed additive with fermented Chinese herbal medicine for treating dairy cow hemafecia Pending CN104256182A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106212860A (en) * 2016-07-20 2016-12-14 内蒙古民族大学 Cattle feedstuff chinese herbal medicine additive
CN107307197A (en) * 2017-07-12 2017-11-03 无为县松林生态养殖有限公司 A kind of ox feed addictive

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106212860A (en) * 2016-07-20 2016-12-14 内蒙古民族大学 Cattle feedstuff chinese herbal medicine additive
CN107307197A (en) * 2017-07-12 2017-11-03 无为县松林生态养殖有限公司 A kind of ox feed addictive

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Application publication date: 20150107