CN102548981B - N1-酰基-5-氟嘧啶酮衍生物 - Google Patents
N1-酰基-5-氟嘧啶酮衍生物 Download PDFInfo
- Publication number
- CN102548981B CN102548981B CN201080045370.7A CN201080045370A CN102548981B CN 102548981 B CN102548981 B CN 102548981B CN 201080045370 A CN201080045370 A CN 201080045370A CN 102548981 B CN102548981 B CN 102548981B
- Authority
- CN
- China
- Prior art keywords
- phenyl
- herbicides
- insecticides
- compounds
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- JBLJSEJOJGOMSW-UHFFFAOYSA-N CN(Cc1ccccc1)C(C(F)=CN1)=NC1=O Chemical compound CN(Cc1ccccc1)C(C(F)=CN1)=NC1=O JBLJSEJOJGOMSW-UHFFFAOYSA-N 0.000 description 1
- JPQWLWFWPXNLPS-UHFFFAOYSA-N CN(Cc1ccccc1)C(C(F)=CN1C(c2ccc[s]2)=O)=NC1=O Chemical compound CN(Cc1ccccc1)C(C(F)=CN1C(c2ccc[s]2)=O)=NC1=O JPQWLWFWPXNLPS-UHFFFAOYSA-N 0.000 description 1
- YXISIJYSMOEQKS-UHFFFAOYSA-N CN(Cc1ccccc1)c(nc(nc1)Cl)c1F Chemical compound CN(Cc1ccccc1)c(nc(nc1)Cl)c1F YXISIJYSMOEQKS-UHFFFAOYSA-N 0.000 description 1
- WHPFEQUEHBULBW-UHFFFAOYSA-N Fc(cnc(Cl)n1)c1Cl Chemical compound Fc(cnc(Cl)n1)c1Cl WHPFEQUEHBULBW-UHFFFAOYSA-N 0.000 description 1
- QIQITDHWZYEEPA-UHFFFAOYSA-N O=C(c1ccc[s]1)Cl Chemical compound O=C(c1ccc[s]1)Cl QIQITDHWZYEEPA-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23222309P | 2009-08-07 | 2009-08-07 | |
| US61/232,223 | 2009-08-07 | ||
| PCT/US2010/044576 WO2011017538A1 (en) | 2009-08-07 | 2010-08-05 | N1-acyl-5-fluoropyrimidinone derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102548981A CN102548981A (zh) | 2012-07-04 |
| CN102548981B true CN102548981B (zh) | 2015-05-13 |
Family
ID=43535292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080045370.7A Active CN102548981B (zh) | 2009-08-07 | 2010-08-05 | N1-酰基-5-氟嘧啶酮衍生物 |
Country Status (33)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5784603B2 (ja) * | 2009-08-07 | 2015-09-24 | ダウ アグロサイエンシィズ エルエルシー | Ｎ１−スルホニル−５−フルオロピリミジノン誘導体 |
| RS56609B1 (sr) | 2011-08-17 | 2018-02-28 | Adama Makhteshim Ltd | 1-supstituisani derivati 5-fluor-3,6-dihidro-6-imino-2(1h)-pirimidinona kao fungicidna sredstva za upotrebu u proizvodnji bilja |
| CN104902757B (zh) | 2012-12-28 | 2019-01-08 | 阿达玛马克西姆股份有限公司 | N-(取代的)-5-氟-4-亚氨基-3-甲基-2-氧代-3,4-二氢嘧啶-1(2h)-羧酸酯衍生物 |
| JP6258969B2 (ja) | 2012-12-28 | 2018-01-10 | アダマ・マクテシム・リミテッド | Ｎ−（置換）−５−フルオロ−４−イミノ−３−メチル−２−オキソ−３，４−ジヒドロピリミジン−１（２ｈ）−カルボキサミド誘導体 |
| WO2014105821A1 (en) * | 2012-12-28 | 2014-07-03 | Dow Agrosciences Llc | 1-(substituted-benzoyl)-5-fluoro-4-imino-3-methyl-3,4-dihydropyrimidin-2(1h)-one derivatives |
| CN112094262A (zh) | 2012-12-31 | 2020-12-18 | 阿达玛马克西姆股份有限公司 | 作为杀真菌剂的化合物 |
| UA129860C2 (uk) | 2013-12-31 | 2025-08-27 | Адама Махтешім Лтд. | 5-фтор-4-іміно-3-(алкіл/заміщений алкіл)-1-(арилсульфоніл)-3,4-дигідропіримідин-2(1h)-он і способи його одержання |
| CR20160344A (es) | 2013-12-31 | 2016-12-19 | Adama Makhteshim Ltd | Mezclas fungicidas sinérgicas para el control fúngico en cereales |
| CN107001397B (zh) | 2014-09-26 | 2020-10-13 | 科慕埃弗西有限公司 | 异氰酸酯衍生的有机硅烷 |
| IL271950B2 (en) | 2017-07-17 | 2024-06-01 | Adama Makhteshim Ltd | Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one |
| CA3118729A1 (en) | 2018-11-05 | 2020-05-14 | Adama Makhteshim Ltd. | Mixtures and compositions comprising 5-fluoro-4-imino-3- methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and methods of use thereof |
| US12466796B2 (en) | 2019-09-23 | 2025-11-11 | Adama Makhteshim Ltd. | Process for preparing 5-(fluoro-4-imino-3-methyl)-1-tosyl-3,4 dihydropyrimidine-(1H)-one and derivatives of the compound |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH421973A (de) * | 1962-05-01 | 1966-10-15 | Hoffmann La Roche | Verfahren zur Herstellung eines Cytosin-Derivates |
| US3309359A (en) * | 1965-10-22 | 1967-03-14 | Hoffmann La Roche | N-mono-acyl-5-fluorocytosine derivatives and process |
| US3368938A (en) * | 1966-01-13 | 1968-02-13 | Hoffmann La Roche | Controlling fungi with 5-fluorocytosine |
| US3868373A (en) * | 1970-01-27 | 1975-02-25 | Hoffmann La Roche | 4-Amino-5-fluoro-2-tri(lower alkyl) silyloxypyrimidines |
| CH579057A5 (enExample) | 1973-09-07 | 1976-08-31 | Hoffmann La Roche | |
| FR2530636A1 (fr) | 1982-07-23 | 1984-01-27 | Rhone Poulenc Agrochimie | Nouveaux derives de la tetrahydro-2,3,6,7 5h-thiazolo (3,2-a) pyrimidine, leur preparation et leur utilisation comme herbicides |
| EP0139613A1 (de) | 1983-08-29 | 1985-05-02 | Ciba-Geigy Ag | N-(2-Nitrophenyl)-4-aminopyrimidin-Derivate, deren Herstellung und Verwendung |
| US4845081A (en) * | 1984-10-18 | 1989-07-04 | University Of Florida | Aminomethyl derivatives of biologically active substances, and enhanced delivery thereof across topical membranes |
| ATE109776T1 (de) | 1988-03-09 | 1994-08-15 | Ciba Geigy Ag | Mittel zum schutz von pflanzen gegen krankheiten. |
| DE3821711A1 (de) * | 1988-06-28 | 1990-02-08 | Bayer Ag | Thiazolopyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel |
| JP3217191B2 (ja) * | 1992-07-16 | 2001-10-09 | ビーエーエスエフ アクチェンゲゼルシャフト | ヘテロ芳香族化合物およびこれを含有する植物保護剤 |
| EP0836602B1 (en) * | 1995-07-05 | 2002-01-30 | E.I. Du Pont De Nemours And Company | Fungicidal pyrimidinones |
| DE69712331T2 (de) * | 1996-03-11 | 2002-11-28 | Syngenta Participations Ag, Basel | Pyrimidin-4-on derivate als pestizidesmittel |
| HRP970239B1 (en) | 1997-05-09 | 2004-04-30 | Inst Ru Er Bouekovic | Process for the preparation of sulfonyl-pyrimidine derivatives with antitumor activity |
| GT199900185A (es) * | 1998-11-06 | 2001-04-18 | Novedosa pirimidin-4-enamina como fungicida. | |
| US7914799B2 (en) * | 2001-08-27 | 2011-03-29 | Immunitor USA, Inc. | Anti-fungal composition |
| US20080269238A1 (en) * | 2004-04-01 | 2008-10-30 | Takeda Pharmaceutical Company Limited | Thiazolopyrimidine Derivative |
| US20080004253A1 (en) * | 2006-06-30 | 2008-01-03 | Bryan James Branstetter | Thiazolopyrimidine modulators of TRPV1 |
| EP2562166B1 (en) * | 2008-01-22 | 2015-08-19 | Dow AgroSciences LLC | 5-fluoro pyrimidine derivatives as fungicides |
| EP2317851B1 (en) | 2008-08-01 | 2014-01-15 | Dow AgroSciences LLC | Use of 5-fluorocytosine as a fungicide |
| PL2389375T3 (pl) | 2009-01-23 | 2015-11-30 | Euro Celtique Sa | Pochodne kwasu hydroksamowego |
| JP5784603B2 (ja) * | 2009-08-07 | 2015-09-24 | ダウ アグロサイエンシィズ エルエルシー | Ｎ１−スルホニル−５−フルオロピリミジノン誘導体 |
-
2010
- 2010-05-08 UA UAA201202731A patent/UA106889C2/uk unknown
- 2010-08-05 LT LTEP10807171.3T patent/LT2519512T/lt unknown
- 2010-08-05 KR KR1020127005927A patent/KR101792285B1/ko not_active Expired - Fee Related
- 2010-08-05 BR BR112012002810-3A patent/BR112012002810B1/pt active IP Right Grant
- 2010-08-05 WO PCT/US2010/044576 patent/WO2011017538A1/en not_active Ceased
- 2010-08-05 PE PE2012000169A patent/PE20120688A1/es not_active Application Discontinuation
- 2010-08-05 HU HUE10807171A patent/HUE045290T2/hu unknown
- 2010-08-05 EP EP10807171.3A patent/EP2519512B1/en active Active
- 2010-08-05 SI SI201031893T patent/SI2519512T1/sl unknown
- 2010-08-05 ES ES10807171T patent/ES2728966T3/es active Active
- 2010-08-05 TR TR2019/08180T patent/TR201908180T4/tr unknown
- 2010-08-05 PT PT10807171T patent/PT2519512T/pt unknown
- 2010-08-05 MX MX2012001620A patent/MX2012001620A/es active IP Right Grant
- 2010-08-05 JP JP2012523950A patent/JP5748754B2/ja active Active
- 2010-08-05 AU AU2010279402A patent/AU2010279402B2/en not_active Ceased
- 2010-08-05 US US12/851,236 patent/US8470839B2/en active Active - Reinstated
- 2010-08-05 EA EA201270253A patent/EA023411B1/ru not_active IP Right Cessation
- 2010-08-05 CA CA2768510A patent/CA2768510C/en not_active Expired - Fee Related
- 2010-08-05 HR HRP20190919TT patent/HRP20190919T1/hr unknown
- 2010-08-05 DK DK10807171.3T patent/DK2519512T3/da active
- 2010-08-05 PL PL10807171T patent/PL2519512T3/pl unknown
- 2010-08-05 IN IN539DEN2012 patent/IN2012DN00539A/en unknown
- 2010-08-05 NZ NZ597570A patent/NZ597570A/en unknown
- 2010-08-05 CN CN201080045370.7A patent/CN102548981B/zh active Active
-
2012
- 2012-01-18 CR CR20120030A patent/CR20120030A/es unknown
- 2012-02-02 ZA ZA2012/00819A patent/ZA201200819B/en unknown
- 2012-02-02 HN HN2012000269A patent/HN2012000269A/es unknown
- 2012-02-03 NI NI201200022A patent/NI201200022A/es unknown
- 2012-02-05 IL IL217952A patent/IL217952A/en active IP Right Grant
- 2012-02-06 CL CL2012000316A patent/CL2012000316A1/es unknown
- 2012-02-06 CO CO12019954A patent/CO6491117A2/es active IP Right Grant
- 2012-02-07 EC ECSP12011653 patent/ECSP12011653A/es unknown
-
2019
- 2019-06-06 CY CY20191100603T patent/CY1122115T1/el unknown
Non-Patent Citations (2)
| Title |
|---|
| Nucleosides with furanyl scaffolds;Sanjib Bera,et al.;《Tetrahedron》;20021231;第58卷;4865-4871 * |
| Nucleosides. XXXIII. N4-Acylated 5-Fluorocytosines and a Direct Synthesis of 5-Fluoro-2"-deoxycytidine;R. DUSCHINSKY,et al.;《Journal of medicinal chemistry》;19660731;第9卷;566-572 * |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102574831B (zh) | N1-磺酰基-5-氟代嘧啶酮衍生物 | |
| CN102548980B (zh) | 5-氟嘧啶酮衍生物 | |
| CN102548981B (zh) | N1-酰基-5-氟嘧啶酮衍生物 | |
| CN102497781B (zh) | N1-取代的-5-氟-2-氧代嘧啶酮-1(2h)-甲酰胺衍生物 | |
| CN102548979B (zh) | 5-氟代-2-氧代嘧啶-1(2h)-甲酸酯衍生物 | |
| CN102762210B (zh) | 2-醛肟-5-氟嘧啶衍生物 | |
| AU2010279409B2 (en) | N1-substituted-5-fluoro-2-oxopyrimidinone-1(2H)-carboxamide derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1172894 Country of ref document: HK |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information |
Inventor after: Boebel Timothy Inventor after: Bryan Kristy Inventor after: Lorsbach Beth Inventor after: Martin Teresita Inventor after: Owen W. John Inventor after: Pobanz Mark Inventor after: Thornburgh Scott Inventor after: Webster Jeffery Inventor after: Yao Chenglin Inventor before: Boebel Timothy Inventor before: Bryan Kristy Inventor before: Lorsbach Beth Inventor before: Martin Teresita Inventor before: Owen W. Inventor before: Pobanz Mark Inventor before: Thornburgh Scott Inventor before: Webster Jeffery Inventor before: Yao Chenglin |
|
| COR | Change of bibliographic data | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1172894 Country of ref document: HK |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20161222 Address after: Beersheba, Israel Patentee after: ADAMA MAKHTESHIM LTD. Address before: indiana Patentee before: Dow Agrosciences LLC |
|
| TR01 | Transfer of patent right |