CN102482701B - I类抗-cea抗体及其使用 - Google Patents

I类抗-cea抗体及其使用 Download PDF

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Publication number
CN102482701B
CN102482701B CN201080039267.1A CN201080039267A CN102482701B CN 102482701 B CN102482701 B CN 102482701B CN 201080039267 A CN201080039267 A CN 201080039267A CN 102482701 B CN102482701 B CN 102482701B
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China
Prior art keywords
antibody
seq
fragment
cea
class
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CN201080039267.1A
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English (en)
Chinese (zh)
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CN102482701A (zh
Inventor
H·J·汉森
C-H·张
D·M·戈德堡
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Immunomedics Inc
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Immunomedics Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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