CN102459347A - 双重可变结构域免疫球蛋白及其用途 - Google Patents

双重可变结构域免疫球蛋白及其用途 Download PDF

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Publication number
CN102459347A
CN102459347A CN2010800293337A CN201080029333A CN102459347A CN 102459347 A CN102459347 A CN 102459347A CN 2010800293337 A CN2010800293337 A CN 2010800293337A CN 201080029333 A CN201080029333 A CN 201080029333A CN 102459347 A CN102459347 A CN 102459347A
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seq
binding
antigen
antibody
amino acid
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T.哈于尔
J.刘
G.A.金斯伯里
E.B.雷利
S.E.摩根-拉普
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AbbVie Inc
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Abbott Laboratories
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CN2010800293337A 2009-05-01 2010-04-30 双重可变结构域免疫球蛋白及其用途 Pending CN102459347A (zh)

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US17471109P 2009-05-01 2009-05-01
US61/174711 2009-05-01
PCT/US2010/033231 WO2010127284A2 (en) 2009-05-01 2010-04-30 Dual variable domain immunoglobulins and uses thereof

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Cited By (3)

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CN105209076A (zh) * 2013-03-15 2015-12-30 阿布维公司 抗体药物偶联物(adc)纯化
CN113234165A (zh) * 2021-05-07 2021-08-10 暨南大学 EpCAM的改造的结合蛋白及其应用
CN113354715A (zh) * 2021-05-07 2021-09-07 暨南大学 Egfr的改造的结合蛋白及其应用

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EP2282769A4 (en) 2008-04-29 2012-04-25 Abbott Lab DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES
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KR20110016959A (ko) 2008-06-03 2011-02-18 아보트 러보러터리즈 이원 가변 도메인 면역글로불린 및 이의 용도
US8822645B2 (en) 2008-07-08 2014-09-02 Abbvie Inc. Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
CN102378768A (zh) * 2009-04-07 2012-03-14 罗氏格黎卡特股份公司 双特异性抗-ErbB-3/抗-c-Met抗体
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PH12012501070A1 (en) 2009-12-08 2017-08-23 Abbott Gmbh & Co Kg Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
WO2011109298A2 (en) 2010-03-02 2011-09-09 Abbott Laboratories Therapeutic dll4 binding proteins
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US9046513B2 (en) 2010-08-26 2015-06-02 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
JP2014509588A (ja) 2011-03-01 2014-04-21 アムジエン・インコーポレーテツド 二特異性結合剤
MX2013014789A (es) 2011-06-16 2014-01-20 Novartis Ag Proteinas solubles para utilizarse como productos terapeuticos.
AR089529A1 (es) 2011-12-30 2014-08-27 Abbvie Inc Proteinas de union especificas duales dirigidas contra il-13 y/o il-17
TW201333039A (zh) * 2011-12-30 2013-08-16 Abbvie Inc 雙可變域免疫球蛋白及其用途
AU2013211939C1 (en) 2012-01-27 2018-06-07 AbbVie Deutschland GmbH & Co. KG Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
CN103382223B (zh) 2012-04-01 2015-06-10 上海益杰生物技术有限公司 针对表皮生长因子受体隐蔽表位和t细胞抗原的多功能抗体多肽
EP2847215A1 (en) * 2012-05-07 2015-03-18 Synthes GmbH Methods and devices for treating intervertebral disc disease
WO2013180200A1 (ja) 2012-05-30 2013-12-05 中外製薬株式会社 標的組織特異的抗原結合分子
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