CN102459202B - 作为脂肪酸酰胺水解酶的抑制剂的异噁唑啉 - Google Patents

作为脂肪酸酰胺水解酶的抑制剂的异噁唑啉 Download PDF

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CN102459202B
CN102459202B CN201080032435.4A CN201080032435A CN102459202B CN 102459202 B CN102459202 B CN 102459202B CN 201080032435 A CN201080032435 A CN 201080032435A CN 102459202 B CN102459202 B CN 102459202B
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substituted
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compound
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CN102459202A (zh
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马克·L·本克
阿尔弗雷多·C·卡斯特罗
劳伦斯·K·陈
凯瑟琳·A·埃文斯
路易斯·格勒涅尔
迈克尔·J·格罗根
伊夫·勒布朗
刘涛
斯特凡·佩卢索
丹尼尔·A·斯奈德
托马斯·T·帝比茨
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Infinity Pharmaceuticals Inc
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CN201080032435.4A 2009-05-18 2010-05-18 作为脂肪酸酰胺水解酶的抑制剂的异噁唑啉 Expired - Fee Related CN102459202B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US17928509P 2009-05-18 2009-05-18
US17928309P 2009-05-18 2009-05-18
US17928009P 2009-05-18 2009-05-18
US61/179,285 2009-05-18
US61/179,283 2009-05-18
US61/179,280 2009-05-18
PCT/US2010/035309 WO2010135360A1 (en) 2009-05-18 2010-05-18 Isoxazolines as inhibitors of fatty acid amide hydrolase

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CN102459202A CN102459202A (zh) 2012-05-16
CN102459202B true CN102459202B (zh) 2015-11-25

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EP (1) EP2432771A4 (enExample)
JP (1) JP2012527467A (enExample)
KR (1) KR20120042766A (enExample)
CN (1) CN102459202B (enExample)
AR (1) AR076687A1 (enExample)
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SI2074123T1 (sl) 2006-10-16 2013-03-29 Bionomics Limited Nove anksiolitične spojine
US8927551B2 (en) 2009-05-18 2015-01-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US9149465B2 (en) 2009-05-18 2015-10-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US20130150346A1 (en) 2010-01-08 2013-06-13 Quest Ventures Ltd. Use of FAAH Inhibitors for Treating Parkinson's Disease and Restless Legs Syndrome
WO2011123719A2 (en) 2010-03-31 2011-10-06 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating abdominal, visceral and pelvic pain
WO2012116415A1 (en) 2011-03-02 2012-09-07 Bionomics Limited Novel small-molecules as therapeutics
CN103649086A (zh) 2011-05-12 2014-03-19 生态学有限公司 制备萘啶的方法
WO2018112843A1 (en) 2016-12-22 2018-06-28 Merck Sharp & Dohme Corp. Heteroaryl piperidine ether allosteric modulators of the m4 muscarinic acetylcholine receptor
JP7052798B2 (ja) 2017-08-10 2022-04-12 大正製薬株式会社 アゾールで置換されたピリジン化合物
US10485790B1 (en) 2018-09-13 2019-11-26 Syneurx International (Taiwan) Corp. Salts of cycloserine compounds and applications thereof
US12698259B2 (en) 2018-10-15 2026-08-04 Dana-Farber Cancer Institute, Inc. Transcriptional enhanced associate domain (TEAD) transcription factor inhibitors and uses thereof
CN110016142B (zh) * 2019-04-30 2021-08-03 合肥工业大学 一种含嘧啶硼酸结构的硅油及其制备方法
US11458149B1 (en) 2019-05-31 2022-10-04 Ikena Oncology, Inc. TEAD inhibitors and uses thereof
BR112021024108A2 (pt) 2019-05-31 2022-03-22 Ikena Oncology Inc Inibidores de tead e usos dos mesmos
EP4043444A1 (en) 2021-02-11 2022-08-17 Basf Se Substituted isoxazoline derivatives
US12595239B2 (en) 2021-02-11 2026-04-07 Basf Se Substituted isoxazoline derivatives
KR20240111312A (ko) 2021-10-25 2024-07-16 카이메라 쎄라퓨틱스 인코포레이티드 Tyk2 분해제 및 이의 용도
EP4238971A1 (en) 2022-03-02 2023-09-06 Basf Se Substituted isoxazoline derivatives
US20250163037A1 (en) 2022-03-02 2025-05-22 Basf Se Substituted isoxazoline derivatives
EP4342885A1 (en) 2022-09-20 2024-03-27 Basf Se N-(3-(aminomethyl)-phenyl)-5-(4-phenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-amine derivatives and similar compounds as pesticides
WO2024061665A1 (en) 2022-09-20 2024-03-28 Basf Se N-(3-(aminomethyl)-phenyl)-5-(4-phenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-amine derivatives and similar compounds as pesticides
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