MX2011012263A - Isoxazolinas como inhibidores de hidrolasa de amida de acido graso. - Google Patents
Isoxazolinas como inhibidores de hidrolasa de amida de acido graso.Info
- Publication number
- MX2011012263A MX2011012263A MX2011012263A MX2011012263A MX2011012263A MX 2011012263 A MX2011012263 A MX 2011012263A MX 2011012263 A MX2011012263 A MX 2011012263A MX 2011012263 A MX2011012263 A MX 2011012263A MX 2011012263 A MX2011012263 A MX 2011012263A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- independently
- aryl
- alkynyl
- carbocyclyl
- Prior art date
Links
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Classifications
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- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
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- Dermatology (AREA)
- Reproductive Health (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17928509P | 2009-05-18 | 2009-05-18 | |
| US17928309P | 2009-05-18 | 2009-05-18 | |
| US17928009P | 2009-05-18 | 2009-05-18 | |
| PCT/US2010/035309 WO2010135360A1 (en) | 2009-05-18 | 2010-05-18 | Isoxazolines as inhibitors of fatty acid amide hydrolase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2011012263A true MX2011012263A (es) | 2012-01-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011012263A MX2011012263A (es) | 2009-05-18 | 2010-05-18 | Isoxazolinas como inhibidores de hidrolasa de amida de acido graso. |
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| AU (1) | AU2010249674A1 (enExample) |
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| TW (1) | TW201043620A (enExample) |
| WO (1) | WO2010135360A1 (enExample) |
| ZA (1) | ZA201108657B (enExample) |
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| US10954231B2 (en) | 2006-10-16 | 2021-03-23 | Bionomics Limited | Anxiolytic compounds |
| SI2074123T1 (sl) | 2006-10-16 | 2013-03-29 | Bionomics Limited | Nove anksiolitične spojine |
| US8927551B2 (en) | 2009-05-18 | 2015-01-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| US9149465B2 (en) | 2009-05-18 | 2015-10-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| US20130150346A1 (en) | 2010-01-08 | 2013-06-13 | Quest Ventures Ltd. | Use of FAAH Inhibitors for Treating Parkinson's Disease and Restless Legs Syndrome |
| WO2011123719A2 (en) | 2010-03-31 | 2011-10-06 | Ironwood Pharmaceuticals, Inc. | Use of faah inhibitors for treating abdominal, visceral and pelvic pain |
| WO2012116415A1 (en) | 2011-03-02 | 2012-09-07 | Bionomics Limited | Novel small-molecules as therapeutics |
| CN103649086A (zh) | 2011-05-12 | 2014-03-19 | 生态学有限公司 | 制备萘啶的方法 |
| WO2018112843A1 (en) | 2016-12-22 | 2018-06-28 | Merck Sharp & Dohme Corp. | Heteroaryl piperidine ether allosteric modulators of the m4 muscarinic acetylcholine receptor |
| JP7052798B2 (ja) | 2017-08-10 | 2022-04-12 | 大正製薬株式会社 | アゾールで置換されたピリジン化合物 |
| US10485790B1 (en) | 2018-09-13 | 2019-11-26 | Syneurx International (Taiwan) Corp. | Salts of cycloserine compounds and applications thereof |
| US12698259B2 (en) | 2018-10-15 | 2026-08-04 | Dana-Farber Cancer Institute, Inc. | Transcriptional enhanced associate domain (TEAD) transcription factor inhibitors and uses thereof |
| CN110016142B (zh) * | 2019-04-30 | 2021-08-03 | 合肥工业大学 | 一种含嘧啶硼酸结构的硅油及其制备方法 |
| US11458149B1 (en) | 2019-05-31 | 2022-10-04 | Ikena Oncology, Inc. | TEAD inhibitors and uses thereof |
| BR112021024108A2 (pt) | 2019-05-31 | 2022-03-22 | Ikena Oncology Inc | Inibidores de tead e usos dos mesmos |
| EP4043444A1 (en) | 2021-02-11 | 2022-08-17 | Basf Se | Substituted isoxazoline derivatives |
| US12595239B2 (en) | 2021-02-11 | 2026-04-07 | Basf Se | Substituted isoxazoline derivatives |
| KR20240111312A (ko) | 2021-10-25 | 2024-07-16 | 카이메라 쎄라퓨틱스 인코포레이티드 | Tyk2 분해제 및 이의 용도 |
| EP4238971A1 (en) | 2022-03-02 | 2023-09-06 | Basf Se | Substituted isoxazoline derivatives |
| US20250163037A1 (en) | 2022-03-02 | 2025-05-22 | Basf Se | Substituted isoxazoline derivatives |
| EP4342885A1 (en) | 2022-09-20 | 2024-03-27 | Basf Se | N-(3-(aminomethyl)-phenyl)-5-(4-phenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-amine derivatives and similar compounds as pesticides |
| WO2024061665A1 (en) | 2022-09-20 | 2024-03-28 | Basf Se | N-(3-(aminomethyl)-phenyl)-5-(4-phenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-amine derivatives and similar compounds as pesticides |
| WO2026107062A1 (en) | 2024-11-13 | 2026-05-21 | Recludix Pharma, Inc. | Stat6 degraders and uses thereof |
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| GB9505651D0 (en) * | 1995-03-21 | 1995-05-10 | Agrevo Uk Ltd | AgrEvo UK Limited |
| AU2003275493A1 (en) * | 2002-10-08 | 2004-05-04 | The Scripps Research Institute | Inhibitors of fatty acid amide hydrolase |
| JP2006516095A (ja) * | 2002-11-14 | 2006-06-22 | ザ スクリップス リサーチ インスティテュート | 脂肪酸アミドヒドロラーゼ（ｆａａｈ）の結晶形 |
| WO2005034952A2 (en) * | 2003-10-07 | 2005-04-21 | The Feinstein Institute For Medical Research | Isoxazole and isothiazole compounds useful in the treatment of inflammation |
| FR2866888B1 (fr) * | 2004-02-26 | 2006-05-05 | Sanofi Synthelabo | Derives de alkylpiperazine- et alkylhomopiperazine- carboxylates, leur preparation et leur application en therapeutique |
| TW200633990A (en) * | 2004-11-18 | 2006-10-01 | Takeda Pharmaceuticals Co | Amide compound |
| US20070155747A1 (en) * | 2005-12-29 | 2007-07-05 | Kadmus Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| ITMI20061279A1 (it) * | 2006-06-30 | 2008-01-01 | Consiglio Nazionale Ricerche | Agonisti nicotinici selettivi per il sottotipo recettoriale alfa7,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| JO3598B1 (ar) * | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| WO2009011904A1 (en) * | 2007-07-19 | 2009-01-22 | Renovis, Inc. | Compounds useful as faah modulators and uses thereof |
| BRPI0821482A2 (pt) * | 2007-12-27 | 2015-07-14 | Bial Portela & Ca Sa | 3-n-fenil-1,3,4-oxadiazolona 5-o-substituída, seu uso, sua composição e seu processo de preparação |
| EP2402332A3 (en) * | 2008-01-25 | 2014-10-29 | E.I. Du Pont De Nemours And Company | Fungicidal heterocyclic compounds |
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- 2010-05-18 TW TW099115796A patent/TW201043620A/zh unknown
- 2010-05-18 WO PCT/US2010/035309 patent/WO2010135360A1/en not_active Ceased
- 2010-05-18 BR BRPI1011049A patent/BRPI1011049A2/pt not_active IP Right Cessation
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- 2010-05-18 MX MX2011012263A patent/MX2011012263A/es not_active Application Discontinuation
- 2010-05-18 SG SG2011085503A patent/SG176168A1/en unknown
- 2010-05-18 AU AU2010249674A patent/AU2010249674A1/en not_active Abandoned
- 2010-05-18 SG SG10201402443PA patent/SG10201402443PA/en unknown
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- 2010-05-18 JP JP2012511971A patent/JP2012527467A/ja not_active Ceased
- 2010-05-18 KR KR1020117030377A patent/KR20120042766A/ko not_active Withdrawn
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- 2010-05-18 EP EP10778279.9A patent/EP2432771A4/en not_active Withdrawn
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- 2011-11-17 IL IL216420A patent/IL216420A0/en unknown
- 2011-11-24 ZA ZA2011/08657A patent/ZA201108657B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ596585A (en) | 2014-01-31 |
| RU2011151635A (ru) | 2013-06-27 |
| EP2432771A1 (en) | 2012-03-28 |
| KR20120042766A (ko) | 2012-05-03 |
| CN102459202A (zh) | 2012-05-16 |
| TW201043620A (en) | 2010-12-16 |
| CN102459202B (zh) | 2015-11-25 |
| CA2762527A1 (en) | 2010-11-25 |
| JP2012527467A (ja) | 2012-11-08 |
| ZA201108657B (en) | 2013-01-30 |
| IL216420A0 (en) | 2012-03-01 |
| EP2432771A4 (en) | 2013-06-05 |
| BRPI1011049A2 (pt) | 2019-09-24 |
| SG176168A1 (en) | 2011-12-29 |
| AU2010249674A1 (en) | 2011-12-15 |
| NZ619076A (en) | 2015-07-31 |
| WO2010135360A1 (en) | 2010-11-25 |
| SG10201402443PA (en) | 2014-10-30 |
| AR076687A1 (es) | 2011-06-29 |
| RU2539595C2 (ru) | 2015-01-20 |
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| FA | Abandonment or withdrawal |