MX2011012263A - Isoxazolinas como inhibidores de hidrolasa de amida de acido graso. - Google Patents
Isoxazolinas como inhibidores de hidrolasa de amida de acido graso.Info
- Publication number
- MX2011012263A MX2011012263A MX2011012263A MX2011012263A MX2011012263A MX 2011012263 A MX2011012263 A MX 2011012263A MX 2011012263 A MX2011012263 A MX 2011012263A MX 2011012263 A MX2011012263 A MX 2011012263A MX 2011012263 A MX2011012263 A MX 2011012263A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- independently
- aryl
- alkynyl
- carbocyclyl
- Prior art date
Links
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Classifications
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- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
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| US17928009P | 2009-05-18 | 2009-05-18 | |
| US17928509P | 2009-05-18 | 2009-05-18 | |
| US17928309P | 2009-05-18 | 2009-05-18 | |
| PCT/US2010/035309 WO2010135360A1 (en) | 2009-05-18 | 2010-05-18 | Isoxazolines as inhibitors of fatty acid amide hydrolase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2011012263A true MX2011012263A (es) | 2012-01-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011012263A MX2011012263A (es) | 2009-05-18 | 2010-05-18 | Isoxazolinas como inhibidores de hidrolasa de amida de acido graso. |
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| JP (1) | JP2012527467A (enExample) |
| KR (1) | KR20120042766A (enExample) |
| CN (1) | CN102459202B (enExample) |
| AR (1) | AR076687A1 (enExample) |
| AU (1) | AU2010249674A1 (enExample) |
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| CA (1) | CA2762527A1 (enExample) |
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| TW (1) | TW201043620A (enExample) |
| WO (1) | WO2010135360A1 (enExample) |
| ZA (1) | ZA201108657B (enExample) |
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| US10954231B2 (en) | 2006-10-16 | 2021-03-23 | Bionomics Limited | Anxiolytic compounds |
| PL2074123T3 (pl) | 2006-10-16 | 2013-04-30 | Bionomics Ltd | Nowe związki o działaniu przeciwlękowym |
| US8927551B2 (en) | 2009-05-18 | 2015-01-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| US9149465B2 (en) | 2009-05-18 | 2015-10-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| US20130150346A1 (en) | 2010-01-08 | 2013-06-13 | Quest Ventures Ltd. | Use of FAAH Inhibitors for Treating Parkinson's Disease and Restless Legs Syndrome |
| WO2011123719A2 (en) | 2010-03-31 | 2011-10-06 | Ironwood Pharmaceuticals, Inc. | Use of faah inhibitors for treating abdominal, visceral and pelvic pain |
| AU2012222874B2 (en) | 2011-03-02 | 2015-04-16 | Bionomics Limited | Novel small-molecules as therapeutics |
| CA2835450C (en) | 2011-05-12 | 2020-05-12 | Bionomics Limited | Methods for preparing naphthyridines |
| WO2018112843A1 (en) | 2016-12-22 | 2018-06-28 | Merck Sharp & Dohme Corp. | Heteroaryl piperidine ether allosteric modulators of the m4 muscarinic acetylcholine receptor |
| CA3072420A1 (en) * | 2017-08-10 | 2019-02-14 | Taisho Pharmaceutical Co., Ltd. | Pyridine compound substituted with azole |
| US10485790B1 (en) | 2018-09-13 | 2019-11-26 | Syneurx International (Taiwan) Corp. | Salts of cycloserine compounds and applications thereof |
| EP3866798A4 (en) * | 2018-10-15 | 2022-07-13 | Dana-Farber Cancer Institute, Inc. | ENHANCED TRANSCRIPTIONAL ASSOCIATED DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND THEIR USES |
| CN110016142B (zh) * | 2019-04-30 | 2021-08-03 | 合肥工业大学 | 一种含嘧啶硼酸结构的硅油及其制备方法 |
| SG11202113129UA (en) | 2019-05-31 | 2021-12-30 | Ikena Oncology Inc | Tead inhibitors and uses thereof |
| CA3141826A1 (en) | 2019-05-31 | 2020-12-03 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| MX2023009402A (es) | 2021-02-11 | 2023-08-23 | Basf Se | Derivados de isoxazolina sustituida. |
| EP4043444A1 (en) | 2021-02-11 | 2022-08-17 | Basf Se | Substituted isoxazoline derivatives |
| CN116888101A (zh) * | 2021-02-11 | 2023-10-13 | 巴斯夫欧洲公司 | 取代的异噁唑啉衍生物 |
| US20250051338A1 (en) | 2021-10-25 | 2025-02-13 | Kymera Therapeutics, Inc. | Tyk2 degraders and uses thereof |
| EP4238971A1 (en) | 2022-03-02 | 2023-09-06 | Basf Se | Substituted isoxazoline derivatives |
| EP4486740A1 (en) | 2022-03-02 | 2025-01-08 | Basf Se | Substituted isoxazoline derivatives |
| EP4342885A1 (en) | 2022-09-20 | 2024-03-27 | Basf Se | N-(3-(aminomethyl)-phenyl)-5-(4-phenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-amine derivatives and similar compounds as pesticides |
| CN120152959A (zh) | 2022-09-20 | 2025-06-13 | 巴斯夫欧洲公司 | 作为杀有害生物剂的n-(3-(氨基甲基)-苯基)-5-(4-苯基)-5-(三氟甲基)-4,5-二氢异噁唑-3-胺衍生物及类似化合物 |
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| GB9505651D0 (en) * | 1995-03-21 | 1995-05-10 | Agrevo Uk Ltd | AgrEvo UK Limited |
| US7662971B2 (en) * | 2002-10-08 | 2010-02-16 | The Scripps Research Institute | Inhibitors of fatty acid amide hydrolase |
| CA2506026A1 (en) * | 2002-11-14 | 2004-05-27 | The Scripps Research Institute | Crystalline form of fatty acid amine hydrolase (faah) |
| WO2005034952A2 (en) * | 2003-10-07 | 2005-04-21 | The Feinstein Institute For Medical Research | Isoxazole and isothiazole compounds useful in the treatment of inflammation |
| FR2866888B1 (fr) * | 2004-02-26 | 2006-05-05 | Sanofi Synthelabo | Derives de alkylpiperazine- et alkylhomopiperazine- carboxylates, leur preparation et leur application en therapeutique |
| TW200633990A (en) * | 2004-11-18 | 2006-10-01 | Takeda Pharmaceuticals Co | Amide compound |
| US20070155747A1 (en) * | 2005-12-29 | 2007-07-05 | Kadmus Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| ITMI20061279A1 (it) * | 2006-06-30 | 2008-01-01 | Consiglio Nazionale Ricerche | Agonisti nicotinici selettivi per il sottotipo recettoriale alfa7,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| JO3598B1 (ar) * | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| WO2009011904A1 (en) * | 2007-07-19 | 2009-01-22 | Renovis, Inc. | Compounds useful as faah modulators and uses thereof |
| CA2710743A1 (en) * | 2007-12-27 | 2009-07-09 | Bial-Portela & Ca., S.A. | 5-o-substituted 3-n-phenyl-1,3,4-oxadiazolones for medical use |
| CN101970432B (zh) * | 2008-01-25 | 2014-05-28 | 杜邦公司 | 杀真菌杂环化合物 |
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2010
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- 2010-05-18 JP JP2012511971A patent/JP2012527467A/ja not_active Ceased
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- 2010-05-18 TW TW099115796A patent/TW201043620A/zh unknown
- 2010-05-18 AU AU2010249674A patent/AU2010249674A1/en not_active Abandoned
- 2010-05-18 KR KR1020117030377A patent/KR20120042766A/ko not_active Withdrawn
- 2010-05-18 CN CN201080032435.4A patent/CN102459202B/zh not_active Expired - Fee Related
- 2010-05-18 WO PCT/US2010/035309 patent/WO2010135360A1/en not_active Ceased
- 2010-05-18 SG SG10201402443PA patent/SG10201402443PA/en unknown
- 2010-05-18 CA CA2762527A patent/CA2762527A1/en not_active Abandoned
- 2010-05-18 RU RU2011151635/04A patent/RU2539595C2/ru not_active IP Right Cessation
- 2010-05-18 SG SG2011085503A patent/SG176168A1/en unknown
- 2010-05-18 EP EP10778279.9A patent/EP2432771A4/en not_active Withdrawn
- 2010-05-18 MX MX2011012263A patent/MX2011012263A/es not_active Application Discontinuation
- 2010-05-18 NZ NZ596585A patent/NZ596585A/en not_active IP Right Cessation
- 2010-05-18 BR BRPI1011049A patent/BRPI1011049A2/pt not_active IP Right Cessation
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2011
- 2011-11-17 IL IL216420A patent/IL216420A0/en unknown
- 2011-11-24 ZA ZA2011/08657A patent/ZA201108657B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2539595C2 (ru) | 2015-01-20 |
| AR076687A1 (es) | 2011-06-29 |
| NZ619076A (en) | 2015-07-31 |
| CA2762527A1 (en) | 2010-11-25 |
| RU2011151635A (ru) | 2013-06-27 |
| KR20120042766A (ko) | 2012-05-03 |
| BRPI1011049A2 (pt) | 2019-09-24 |
| WO2010135360A1 (en) | 2010-11-25 |
| CN102459202B (zh) | 2015-11-25 |
| SG10201402443PA (en) | 2014-10-30 |
| TW201043620A (en) | 2010-12-16 |
| ZA201108657B (en) | 2013-01-30 |
| NZ596585A (en) | 2014-01-31 |
| CN102459202A (zh) | 2012-05-16 |
| AU2010249674A1 (en) | 2011-12-15 |
| IL216420A0 (en) | 2012-03-01 |
| EP2432771A4 (en) | 2013-06-05 |
| JP2012527467A (ja) | 2012-11-08 |
| EP2432771A1 (en) | 2012-03-28 |
| SG176168A1 (en) | 2011-12-29 |
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| FA | Abandonment or withdrawal |