CN102428185B - 破囊壶菌、脂肪酸组合物和其制备方法及用途 - Google Patents

破囊壶菌、脂肪酸组合物和其制备方法及用途 Download PDF

Info

Publication number
CN102428185B
CN102428185B CN200980159422.0A CN200980159422A CN102428185B CN 102428185 B CN102428185 B CN 102428185B CN 200980159422 A CN200980159422 A CN 200980159422A CN 102428185 B CN102428185 B CN 102428185B
Authority
CN
China
Prior art keywords
biomass
thraustochytrid
fatty acids
weight
isolated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN200980159422.0A
Other languages
English (en)
Chinese (zh)
Other versions
CN102428185A (zh
Inventor
K·E·阿普特
J·W·普菲弗三世
J·M·汉森
P·W·伯赫恩斯
R·泽克尔
T·L·斯托尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42739887&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN102428185(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Priority to CN201811114403.3A priority Critical patent/CN109609562A/zh
Priority to CN201510471114.9A priority patent/CN104988078B/zh
Publication of CN102428185A publication Critical patent/CN102428185A/zh
Application granted granted Critical
Publication of CN102428185B publication Critical patent/CN102428185B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C12N1/125—Unicellular algae isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/89—Algae ; Processes using algae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Pain & Pain Management (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Animal Husbandry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Edible Oils And Fats (AREA)
CN200980159422.0A 2009-03-19 2009-03-19 破囊壶菌、脂肪酸组合物和其制备方法及用途 Active CN102428185B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201811114403.3A CN109609562A (zh) 2009-03-19 2009-03-19 破囊壶菌、脂肪酸组合物和其制备方法及用途
CN201510471114.9A CN104988078B (zh) 2009-03-19 2009-03-19 破囊壶菌、脂肪酸组合物和其制备方法及用途

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2009/001720 WO2010107415A1 (en) 2009-03-19 2009-03-19 Thraustochytrids, fatty acid compositions, and methods of making and uses thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN201510471114.9A Division CN104988078B (zh) 2009-03-19 2009-03-19 破囊壶菌、脂肪酸组合物和其制备方法及用途
CN201811114403.3A Division CN109609562A (zh) 2009-03-19 2009-03-19 破囊壶菌、脂肪酸组合物和其制备方法及用途

Publications (2)

Publication Number Publication Date
CN102428185A CN102428185A (zh) 2012-04-25
CN102428185B true CN102428185B (zh) 2020-07-10

Family

ID=42739887

Family Applications (2)

Application Number Title Priority Date Filing Date
CN200980159422.0A Active CN102428185B (zh) 2009-03-19 2009-03-19 破囊壶菌、脂肪酸组合物和其制备方法及用途
CN201811114403.3A Pending CN109609562A (zh) 2009-03-19 2009-03-19 破囊壶菌、脂肪酸组合物和其制备方法及用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201811114403.3A Pending CN109609562A (zh) 2009-03-19 2009-03-19 破囊壶菌、脂肪酸组合物和其制备方法及用途

Country Status (17)

Country Link
EP (6) EP4353826A2 (ko)
JP (1) JP5762393B2 (ko)
KR (1) KR101861375B1 (ko)
CN (2) CN102428185B (ko)
AU (2) AU2009342676B2 (ko)
BR (1) BRPI0923968B1 (ko)
CA (1) CA2754952C (ko)
DK (3) DK2408922T3 (ko)
EA (1) EA030161B1 (ko)
ES (3) ES2757878T3 (ko)
IL (1) IL215141A0 (ko)
MX (2) MX356532B (ko)
NZ (3) NZ703725A (ko)
PL (1) PL2408922T3 (ko)
SG (1) SG174383A1 (ko)
WO (1) WO2010107415A1 (ko)
ZA (1) ZA201107517B (ko)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2408922T3 (en) 2009-03-19 2016-12-05 Dsm Ip Assets Bv Thraustochytrids, FATTY ACID COMPOSITIONS AND METHODS OF MAKING AND USE THEREOF
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
CN102884201B (zh) 2010-01-19 2016-04-13 帝斯曼知识产权资产管理有限公司 生产二十碳五烯酸的微生物、脂肪酸组成物及其制作方法与用途
EP3617318A1 (en) 2010-06-01 2020-03-04 DSM IP Assets B.V. Extraction of lipid from cells and products therefrom
CN108771240A (zh) * 2011-07-21 2018-11-09 帝斯曼知识产权资产管理有限公司 脂肪酸组合物
EA034980B1 (ru) * 2011-07-21 2020-04-14 ДСМ АйПи АССЕТС Б.В. Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции жирных кислот, способы их получения и применения
AU2014369042B2 (en) 2013-12-20 2020-04-30 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
AU2014369045B2 (en) 2013-12-20 2020-02-27 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
SG11201605009RA (en) 2013-12-20 2016-07-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
KR102426987B1 (ko) 2013-12-20 2022-07-28 디에스엠 아이피 어셋츠 비.브이. 미생물 세포로부터의 미생물 오일의 수득 방법
CN103725617A (zh) * 2014-01-01 2014-04-16 北京大学深圳研究生院 一株富含甘油酯型DHA的破囊壶菌Aurantiochytrium sp.及其应用
MX2016015132A (es) * 2014-05-22 2017-08-10 Synthetic Genomics Inc Cepas de labyrinthulomycete para producir acido docosahexanoico.
CN104206864A (zh) * 2014-08-28 2014-12-17 青岛海智源生命科技有限公司 一种富含二十二碳六烯酸的饲料
US10874120B2 (en) * 2014-12-12 2020-12-29 Dsm Ip Assets B.V. Feed supplement material for use in aquaculture feed
FR3038913B1 (fr) * 2015-07-17 2020-05-01 Fermentalg Biomasse de thraustochytrides, procede de culture et utilisations
FR3038914B1 (fr) * 2015-07-17 2020-03-13 Fermentalg Biomasse de thraustochytrides, procede de culture et utilisations
WO2017131188A1 (ja) * 2016-01-28 2017-08-03 日本水産株式会社 高度不飽和脂肪酸を含む油脂の製造方法
US11419350B2 (en) 2016-07-01 2022-08-23 Corbion Biotech, Inc. Feed ingredients comprising lysed microbial cells
GB201718423D0 (en) * 2017-11-07 2017-12-20 Polglase Jane Lesley Microorganism
FR3085825B1 (fr) 2018-09-14 2021-07-16 Fermentalg Huile de microorganismes riche en acide docosahexaenoique
FR3085962B1 (fr) 2018-09-14 2021-06-18 Fermentalg Procede d'extracton d'une huile riche en pufa
WO2020141206A1 (en) 2019-01-03 2020-07-09 Corbion Biotech Inc. Process for manufacturing lysed cell suspension
FR3111912A1 (fr) 2020-06-24 2021-12-31 Fermentalg Procédé de culture de microorganismes pour l’accumulation de lipides
SE2151489A1 (en) * 2021-12-07 2023-06-08 Mycorena Ab A food product or food ingredient comprising fungi biomass with an increased intracellular fat content

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451567B1 (en) * 1988-09-07 2002-09-17 Omegatech, Inc. Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms
US5130242A (en) 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5407957A (en) 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
JPH08511533A (ja) 1993-06-09 1996-12-03 マーテック・バイオサイエンスィズ・コーポレーション 神経学的障害の治療に有用な方法および医薬用組成物
US20050027004A1 (en) 1993-06-09 2005-02-03 Martek Biosciences Corporation Methods of treating senile dementia and Alzheimer's diseases using docosahexaenoic acid and arachidonic acid compositions
EP0823475B1 (en) 1995-04-17 2009-06-17 National Institute of Advanced Industrial Science and Technology Novel microorganisms capable of producing highly unsaturated fatty acids and process for producing highly unsaturated fatty acids by using the microorganisms
WO1996040106A2 (en) * 1995-06-07 1996-12-19 Martek Biosciences Corporation Methods for controlling highly unsaturated fatty acid content in various tissues
DK0894142T4 (da) 1996-03-28 2014-02-24 Dsm Ip Assets Bv Mikrobiel olie der omfatter en polyumættet fedtsyre og proces til produktion af olie fra pasteuriseret og granuleret biomasse.
DK1785492T3 (da) * 1996-07-23 2010-07-26 Nagase Chemtex Corp Fremgangsmåde til fremstilling af docosahexaensyre og docosapentaensyre
AU748220C (en) 1997-08-01 2003-02-27 Martek Biosciences Corporation DHA-containing nutritional compositions and methods for their production
JP4283351B2 (ja) 1998-08-27 2009-06-24 サントリー酒類株式会社 新規な油脂組成物の製造方法および用途
WO2000050547A1 (en) 1999-02-26 2000-08-31 Monsanto Company Process for separating a triglyceride comprising a docosahexaenoic acid residue from a mixture of triglycerides
ES2675517T3 (es) 2000-01-19 2018-07-11 Dsm Ip Assets B.V. Proceso de extracción sin solvente
DE10151155A1 (de) 2001-10-19 2003-05-08 Nutrinova Gmbh Native PUFA-Triglyceridmischungen mit einem hohen Gehalt an mehrfach ungesättigten Fettsäuren sowie Verfahren zu deren Herstellung und deren Verwendung
EP2384750A1 (en) * 2002-09-27 2011-11-09 Martek Biosciences Corporation Improved Glycemic Control for Prediabetes and/or Diabetes Type II using Docohexaenoic Acid
JP4280158B2 (ja) 2002-12-27 2009-06-17 富士フイルム株式会社 ドコサヘキサエン酸生産能を有する微生物及びその利用
WO2004084882A1 (en) * 2003-03-27 2004-10-07 Suntory Limited Use of arachidonic acid for normalization of infradian rhythm
CN1264967C (zh) * 2004-12-08 2006-07-19 中国海洋大学 海洋真菌裂殖壶菌ouc88的工业应用
DE102005003625A1 (de) 2005-01-26 2006-07-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Verfahren zur Herstellung einer DHA-haltigen Fettsäure-Zusammensetzung
MX300085B (es) 2005-07-01 2012-06-08 Martek Biosciences Corp Producto oleoso que contiene acido graso poli-insaturado y usos y produccion del mismo.
US9145534B2 (en) * 2006-07-28 2015-09-29 Bioriginal Food & Science Corporation Fat containing composition
US9023616B2 (en) 2006-08-01 2015-05-05 Dsm Nutritional Products Ag Oil producing microbes and method of modification thereof
US20100086979A1 (en) * 2006-10-27 2010-04-08 Thomas Kiy Production of omega-3 fatty acids in microflora of thraustochytriales using modified media
CL2008002020A1 (es) 2007-07-12 2008-11-14 Ocean Nutrition Canada Ltd Metodo de modificacion de un aceite, que comprende hidrolizar gliceridos con una solucion de lipasa thermomyces lanuginosus, separar la fraccion de acido graso saturado de la fraccion de glicerido hidrolizado y esterificar los gliceridos hidrolizados en la presencia de candida antarctica lipasa b; y composicion de aceite.
TWI337229B (en) 2007-08-27 2011-02-11 Htc Corp Portable electronic apparatus with dual hinges
DK2408922T3 (en) 2009-03-19 2016-12-05 Dsm Ip Assets Bv Thraustochytrids, FATTY ACID COMPOSITIONS AND METHODS OF MAKING AND USE THEREOF

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Thraustochytrid Marine Protists: Production of PUFAs and Other Emerging Technologies;RAGHUKUMAR;《MARINE BIOTECHNOL》;20081130;第10卷(第6期);631-640 *

Also Published As

Publication number Publication date
EP4183883A1 (en) 2023-05-24
SG174383A1 (en) 2011-11-28
CA2754952C (en) 2018-11-06
NZ703725A (en) 2017-06-30
AU2009342676A1 (en) 2011-11-03
JP2012520673A (ja) 2012-09-10
IL215141A0 (en) 2011-12-29
ES2757878T3 (es) 2020-04-30
EP3530740A1 (en) 2019-08-28
CN109609562A (zh) 2019-04-12
EP2408922A4 (en) 2013-06-05
EP3196309A2 (en) 2017-07-26
DK3530740T3 (da) 2021-10-18
JP5762393B2 (ja) 2015-08-12
DK2408922T3 (en) 2016-12-05
ES2602121T3 (es) 2017-02-17
EP4353826A2 (en) 2024-04-17
EP3530740B1 (en) 2021-07-28
KR101861375B1 (ko) 2018-05-25
NZ595599A (en) 2013-12-20
ZA201107517B (en) 2012-06-27
EA201190218A1 (ru) 2012-07-30
BRPI0923968A2 (pt) 2015-07-21
WO2010107415A1 (en) 2010-09-23
EP3196309B1 (en) 2019-09-04
MX356532B (es) 2018-06-01
CA2754952A1 (en) 2010-09-23
NZ613586A (en) 2015-06-26
AU2009342676B2 (en) 2016-02-25
AU2016203427B2 (en) 2018-03-22
EP2408922A1 (en) 2012-01-25
EA030161B1 (ru) 2018-06-29
BRPI0923968A8 (pt) 2018-11-06
DK3196309T3 (da) 2019-11-25
EP2408922B1 (en) 2016-08-10
CN102428185A (zh) 2012-04-25
EP3196309A3 (en) 2017-09-06
AU2016203427A1 (en) 2016-06-16
PL2408922T3 (pl) 2017-02-28
MX2011009750A (es) 2011-09-29
ES2895261T3 (es) 2022-02-18
EP3926050A1 (en) 2021-12-22
BRPI0923968B1 (pt) 2020-04-28
KR20110128944A (ko) 2011-11-30

Similar Documents

Publication Publication Date Title
CN102428185B (zh) 破囊壶菌、脂肪酸组合物和其制备方法及用途
US10757959B2 (en) Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
TWI653336B (zh) 生產二十碳五烯酸之微生物、脂肪酸組成物及其製作方法與用途
JP6208125B2 (ja) 脂肪酸組成物
CN104988078B (zh) 破囊壶菌、脂肪酸组合物和其制备方法及用途
JP6362218B2 (ja) ヤブレツボカビ、脂肪酸組成物、ならびにその作出および使用の方法
JP2018108096A (ja) ヤブレツボカビ、脂肪酸組成物、ならびにその作出および使用の方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: DISIMAN INTELLECTUAL PROPERTY ASSETS B.V.

Free format text: FORMER OWNER: MARTEK BIOSCIENCES CORP.

Effective date: 20130220

C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20130220

Address after: Holland Heerlen

Applicant after: Disiman Intellectual Property Assets B.V.

Address before: American Maryland

Applicant before: Martek Biosciences Corp.

C53 Correction of patent of invention or patent application
CB02 Change of applicant information

Address after: Holland Heerlen

Applicant after: DSM IP ASSETS B.V.

Address before: Holland Heerlen

Applicant before: Disiman Intellectual Property Assets B.V.

COR Change of bibliographic data

Free format text: CORRECT: APPLICANT; FROM: DISIMAN INTELLECTUAL PROPERTY ASSETS B.V. TO: DSM IP ASSETS BV

GR01 Patent grant
GR01 Patent grant