MX2016015132A - Cepas de labyrinthulomycete para producir acido docosahexanoico. - Google Patents

Cepas de labyrinthulomycete para producir acido docosahexanoico.

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Publication number
MX2016015132A
MX2016015132A MX2016015132A MX2016015132A MX2016015132A MX 2016015132 A MX2016015132 A MX 2016015132A MX 2016015132 A MX2016015132 A MX 2016015132A MX 2016015132 A MX2016015132 A MX 2016015132A MX 2016015132 A MX2016015132 A MX 2016015132A
Authority
MX
Mexico
Prior art keywords
strains
docosahexaenoic acid
dha
increased
producing docosahexaenoic
Prior art date
Application number
MX2016015132A
Other languages
English (en)
Inventor
R Radakovits Randor
L Champagne Michele
Original Assignee
Synthetic Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthetic Genomics Inc filed Critical Synthetic Genomics Inc
Publication of MX2016015132A publication Critical patent/MX2016015132A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/10—Protozoa; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/10—Protozoa; Culture media therefor
    • C12N1/105—Protozoal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/90—Protozoa ; Processes using protozoa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P30/00—Technologies relating to oil refining and petrochemical industry
    • Y02P30/20—Technologies relating to oil refining and petrochemical industry using bio-feedstock

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Animal Husbandry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se divulgan cepas de labyrinthulomycetes mejoradas que producen aceites microbianos con aumento de contenido de ácido decosahecanoico (DHA). Las cepas tienen mayor productividad con respecto a una cepa de tipo salvaje. Asimismo, se proveen composiciones de aceite microbiano con aumento de contenido de DHA. Tambien se incluyen métodos para mejorar las cepas para la producción de lípidos, tal como DHA.
MX2016015132A 2014-05-22 2015-05-22 Cepas de labyrinthulomycete para producir acido docosahexanoico. MX2016015132A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462002107P 2014-05-22 2014-05-22
PCT/US2015/032308 WO2015179844A2 (en) 2014-05-22 2015-05-22 Labyrinthulomycete strains for producing docosahexaenoic acid

Publications (1)

Publication Number Publication Date
MX2016015132A true MX2016015132A (es) 2017-08-10

Family

ID=54554984

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016015132A MX2016015132A (es) 2014-05-22 2015-05-22 Cepas de labyrinthulomycete para producir acido docosahexanoico.

Country Status (9)

Country Link
US (2) US20160177255A1 (es)
EP (1) EP3146059B1 (es)
JP (1) JP6901859B2 (es)
CN (2) CN113278529B (es)
AU (1) AU2015263881B2 (es)
BR (1) BR112016027101B1 (es)
CA (1) CA2949711A1 (es)
MX (1) MX2016015132A (es)
WO (1) WO2015179844A2 (es)

Families Citing this family (13)

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EP3265567B1 (en) 2015-03-02 2020-07-29 Conagen Inc. Regulatory elements from labyrinthulomycetes microorganisms
EP3795586A3 (en) 2016-03-16 2021-06-23 Conagen Inc. Production of proteins in labyrinthulomycetes
US10851395B2 (en) * 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
BR112019000430A2 (pt) * 2016-07-13 2019-07-09 Dsm Ip Assets Bv sistema crispr-cas para uma célula hospedeira de algas
US10633454B2 (en) 2016-11-01 2020-04-28 Conagen Inc. Expression of modified glycoproteins and glycopeptides
WO2019151452A1 (ja) * 2018-01-31 2019-08-08 日本水産株式会社 微生物の乾燥粉末及びその製造方法
KR102100650B1 (ko) * 2018-06-29 2020-04-16 씨제이제일제당 주식회사 신규한 트라우즈토카이트리움 속 균주, 및 이를 이용한 다중불포화지방산 생산방법
CN109022284B (zh) * 2018-09-03 2021-05-21 杭州园泰生物科技有限公司 提高球等鞭金藻生物量以及dha产量的方法
CN110157748A (zh) * 2019-03-25 2019-08-23 厦门大学 一种裂殖壶菌发酵产多不饱和脂肪酸的调控方法
CN110157770A (zh) * 2019-05-06 2019-08-23 中国科学院水生生物研究所 一种高通量筛选高产油裂殖壶菌突变体的方法
CN114746393A (zh) * 2019-08-30 2022-07-12 Ciimar-海洋与环境跨学科研究中心 卤代的化合物、其方法和用途
KR20220163979A (ko) * 2020-04-03 2022-12-12 마라 리뉴어블즈 코퍼레이션 높은 수준의 오메가-3 지방산을 갖는 미생물 오일
WO2023094996A1 (en) * 2021-11-24 2023-06-01 Dsm Ip Assets B.V. COMPOSITIONS HAVING HIGH LEVELS OF DPA (n-3) AND METHODS FOR PRODUCING

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ES2626018T3 (es) * 2005-06-07 2017-07-21 Dsm Nutritional Products Ag Microorganismos eucariotas para la producción de lípidos y antioxidantes
JP2009519032A (ja) * 2005-12-16 2009-05-14 アヴェスタゲン リミテッド ドコサヘキサエン酸（ｄｈａ）産生スラウストキトリウム菌株‐ｓｃ１
AU2007351658B2 (en) * 2006-08-01 2013-05-30 Dsm Nutritional Products Ag Oil producing microbes and methods of modification thereof
EP2105506A1 (de) * 2008-03-26 2009-09-30 Lonza Ag Verfahren zur Herstellung PUFAs enthaltender Öle unter Verwendung von Mikroorganismen der Ordnung Labyrinthulomycota
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CN102787074B (zh) * 2011-05-20 2016-06-08 罗盖特兄弟公司 生产角鲨烯的微藻新菌株
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Also Published As

Publication number Publication date
JP2017518747A (ja) 2017-07-13
US20200385668A1 (en) 2020-12-10
EP3146059B1 (en) 2019-09-18
AU2015263881A1 (en) 2016-12-15
CN107075538A (zh) 2017-08-18
BR112016027101A2 (pt) 2017-12-26
CA2949711A1 (en) 2015-11-26
EP3146059A4 (en) 2017-11-22
BR112016027101B1 (pt) 2022-11-08
WO2015179844A2 (en) 2015-11-26
US20160177255A1 (en) 2016-06-23
JP6901859B2 (ja) 2021-07-14
CN113278529A (zh) 2021-08-20
CN113278529B (zh) 2023-10-10
WO2015179844A3 (en) 2016-01-14
EP3146059A2 (en) 2017-03-29
AU2015263881B2 (en) 2020-06-18

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