CN102421900B - 用于抑制Eg5和VEGF基因表达的脂质配制的组合物以及方法 - Google Patents

用于抑制Eg5和VEGF基因表达的脂质配制的组合物以及方法 Download PDF

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CN102421900B
CN102421900B CN201080020483.1A CN201080020483A CN102421900B CN 102421900 B CN102421900 B CN 102421900B CN 201080020483 A CN201080020483 A CN 201080020483A CN 102421900 B CN102421900 B CN 102421900B
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dsrna
lipid
composition
acid
nucleic acid
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CN102421900A (zh
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D·巴姆克罗特
A·阿金克
D·萨
T·诺沃布兰塞瓦
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Alnylam Pharmaceuticals Inc
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CN201080020483.1A 2009-03-12 2010-03-12 用于抑制Eg5和VEGF基因表达的脂质配制的组合物以及方法 Expired - Fee Related CN102421900B (zh)

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US15978809P 2009-03-12 2009-03-12
US61/159,788 2009-03-12
US23157909P 2009-08-05 2009-08-05
US61/231,579 2009-08-05
US28594709P 2009-12-11 2009-12-11
US61/285,947 2009-12-11
PCT/US2010/027210 WO2010105209A1 (en) 2009-03-12 2010-03-12 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES

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CN102421900B true CN102421900B (zh) 2015-07-22

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CN201510338694.4A Expired - Fee Related CN104922699B (zh) 2009-03-12 2010-03-12 脂质配制的组合物以及用于抑制Eg5和VEGF基因表达的方法

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US (2) US20100267806A1 (https=)
EP (1) EP2406376A1 (https=)
JP (2) JP6032724B2 (https=)
CN (2) CN102421900B (https=)
AU (1) AU2010223967B2 (https=)
CA (1) CA2754043A1 (https=)
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WO (1) WO2010105209A1 (https=)

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