CN102326082A - 凝固蛋白原原料及其制造方法、使用它测定来自生物的生理活性物质的方法和测定装置 - Google Patents

凝固蛋白原原料及其制造方法、使用它测定来自生物的生理活性物质的方法和测定装置 Download PDF

Info

Publication number
CN102326082A
CN102326082A CN2010800085809A CN201080008580A CN102326082A CN 102326082 A CN102326082 A CN 102326082A CN 2010800085809 A CN2010800085809 A CN 2010800085809A CN 201080008580 A CN201080008580 A CN 201080008580A CN 102326082 A CN102326082 A CN 102326082A
Authority
CN
China
Prior art keywords
coagulogen
lal
physiologically active
raw material
active substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800085809A
Other languages
English (en)
Chinese (zh)
Inventor
薮崎克己
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Publication of CN102326082A publication Critical patent/CN102326082A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN2010800085809A 2009-02-19 2010-02-19 凝固蛋白原原料及其制造方法、使用它测定来自生物的生理活性物质的方法和测定装置 Pending CN102326082A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009037150A JP5437660B2 (ja) 2009-02-19 2009-02-19 コアギュロゲン原料及びその製造方法、それを用いた生物由来の生理活性物質の測定方法及び測定装置
JP2009-037150 2009-02-19
PCT/JP2010/052551 WO2010095718A1 (ja) 2009-02-19 2010-02-19 コアギュロゲン原料及びその製造方法、それを用いた生物由来の生理活性物質の測定方法及び測定装置

Publications (1)

Publication Number Publication Date
CN102326082A true CN102326082A (zh) 2012-01-18

Family

ID=42633995

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800085809A Pending CN102326082A (zh) 2009-02-19 2010-02-19 凝固蛋白原原料及其制造方法、使用它测定来自生物的生理活性物质的方法和测定装置

Country Status (7)

Country Link
US (1) US8790885B2 (https=)
EP (1) EP2400302A4 (https=)
JP (1) JP5437660B2 (https=)
KR (1) KR20110132334A (https=)
CN (1) CN102326082A (https=)
CA (1) CA2753062A1 (https=)
WO (1) WO2010095718A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106645721A (zh) * 2016-09-30 2017-05-10 广州鸿琪光学仪器科技有限公司 一种凝固酶检测试剂、反应垫、其制备方法及试剂盒
CN108956543A (zh) * 2017-05-18 2018-12-07 微采视像科技股份有限公司 凝血酶原时间的测定方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2755276A1 (en) * 2009-03-13 2010-09-16 Kowa Company, Ltd. Method for measuring physiologically active substance of biological origin, program for implementing the same, and apparatus for measuring physiologically active substance of biological origin
JP5981338B2 (ja) * 2009-06-26 2016-08-31 チャールズ リバー ラボラトリーズ， インコーポレイテッド 加熱処理したリムルスアメーバ様細胞溶解物
WO2012053515A1 (ja) * 2010-10-18 2012-04-26 Obata Toru ゲル粒子測定試薬及びこれを用いた測定方法
JPWO2013062013A1 (ja) * 2011-10-26 2015-04-02 興和株式会社 生物由来の生理活性物質の測定方法及び、それに用いられる微粒子及び抽出液
DE102012110288A1 (de) * 2012-10-26 2014-04-30 Leibniz-Institut Für Neue Materialien Gemeinnützige Gmbh Verfahren zur Detektion von Endotoxinen und/oder 1,3-beta-D-Glucanen in einer Probe
JP2016529939A (ja) 2013-06-12 2016-09-29 キンバリー クラーク ワールドワイド インコーポレイテッド 多孔質ポリオレフィン繊維から形成された不織布ウェブを含む吸収性物品
WO2025181654A1 (en) * 2024-02-26 2025-09-04 Smith & Nephew, Inc. Methods for measurement of endotoxin contaminants in enzymatic compositions

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0476459A (ja) * 1990-07-19 1992-03-11 Taiyo Fishery Co Ltd β―グルカン類に対する特異性の高いアメボサイト・ライセート及びその製造方法
CN1087724A (zh) * 1992-05-08 1994-06-08 生化学工业株式会社 前处理剂、前处理方法、使用经前处理的试样的测定法、测定用药盒以及感染症的诊断方法
EP0613004A1 (en) * 1993-02-26 1994-08-31 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Reagent for endotoxin assay and method for endotoxin assay using the same
CN1469124A (zh) * 2003-06-04 2004-01-21 湛江安度斯生物有限公司 一种血液的细菌内毒素定量检测方法—同系统模型法
CN1621841A (zh) * 2003-11-29 2005-06-01 丁友玲 抗干扰鲎试剂的制备工艺
CN1632579A (zh) * 2005-01-13 2005-06-29 丁友玲 鲎试剂检测用的血液前处理法
WO2008038329A1 (en) * 2006-09-25 2008-04-03 Kowa Kabushiki Kaisha Apparatus for gelation measurement and sample cell
WO2008139544A1 (ja) * 2007-05-01 2008-11-20 Kowa Company, Ltd. ゲル化測定装置および試料セル
CN101368967A (zh) * 2008-08-28 2009-02-18 湛江安度斯生物有限公司 一种微量终点显色鲎试验方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322217A (en) 1980-06-27 1982-03-30 Mallinckrodt, Inc. Process for preparing Limulus lysate
BE889407A (fr) * 1980-06-27 1981-10-16 Mallinckrodt Inc Amelioration du procede de preparation d'un lysat de limule
DK255887D0 (da) 1987-05-20 1987-05-20 Claus Koch Immunoassay
JP2737514B2 (ja) 1992-01-24 1998-04-08 和光純薬工業株式会社 エンドトキシン測定用試料の前処理方法
WO1996006858A1 (en) * 1994-09-01 1996-03-07 Seikagaku Corporation (1→3)-β-D-GLUCAN-BINDING PROTEIN, ANTIBODY THAT RECOGNIZES THE PROTEIN, AND USE OF THE PROTEIN AND ANTIBODY
JPH10293129A (ja) 1997-04-18 1998-11-04 Nof Corp リン脂質中のエンドトキシン測定法
JP3913132B2 (ja) 2002-07-29 2007-05-09 東亜ディーケーケー株式会社 エンドトキシン測定方法及び装置、並びにエンドトキシン計測システム
EP1836492B1 (en) * 2005-01-13 2008-12-31 Charles River Laboratories, Inc. Method for classifying a microorganism in a biological sample
US20100119530A1 (en) 2006-07-06 2010-05-13 Wenchao Song Regulation of TLR Signaling by Complement
JP4940085B2 (ja) * 2007-10-02 2012-05-30 興和株式会社 エンドトキシン測定用の容器

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0476459A (ja) * 1990-07-19 1992-03-11 Taiyo Fishery Co Ltd β―グルカン類に対する特異性の高いアメボサイト・ライセート及びその製造方法
CN1087724A (zh) * 1992-05-08 1994-06-08 生化学工业株式会社 前处理剂、前处理方法、使用经前处理的试样的测定法、测定用药盒以及感染症的诊断方法
EP0613004A1 (en) * 1993-02-26 1994-08-31 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Reagent for endotoxin assay and method for endotoxin assay using the same
CN1469124A (zh) * 2003-06-04 2004-01-21 湛江安度斯生物有限公司 一种血液的细菌内毒素定量检测方法—同系统模型法
CN1621841A (zh) * 2003-11-29 2005-06-01 丁友玲 抗干扰鲎试剂的制备工艺
CN1632579A (zh) * 2005-01-13 2005-06-29 丁友玲 鲎试剂检测用的血液前处理法
WO2008038329A1 (en) * 2006-09-25 2008-04-03 Kowa Kabushiki Kaisha Apparatus for gelation measurement and sample cell
WO2008139544A1 (ja) * 2007-05-01 2008-11-20 Kowa Company, Ltd. ゲル化測定装置および試料セル
CN101368967A (zh) * 2008-08-28 2009-02-18 湛江安度斯生物有限公司 一种微量终点显色鲎试验方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SHIN NAKAMURA等: "A Clottable Protein (Coagulogen) from Amoebocyte Lysate of Japanese Horseshoe Crab (Tachypleus tridentatus). Its Isolation and Biochemical Properties", 《THE JOURNAL OF BIOCHEMISTRY》 *
王志光，杜良成: "中国鲎试剂中凝固蛋白原的快速纯化", 《昆明医学院学报》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106645721A (zh) * 2016-09-30 2017-05-10 广州鸿琪光学仪器科技有限公司 一种凝固酶检测试剂、反应垫、其制备方法及试剂盒
CN108956543A (zh) * 2017-05-18 2018-12-07 微采视像科技股份有限公司 凝血酶原时间的测定方法

Also Published As

Publication number Publication date
KR20110132334A (ko) 2011-12-07
JP2010190801A (ja) 2010-09-02
CA2753062A1 (en) 2010-08-26
JP5437660B2 (ja) 2014-03-12
WO2010095718A1 (ja) 2010-08-26
US20120040385A1 (en) 2012-02-16
US8790885B2 (en) 2014-07-29
EP2400302A4 (en) 2012-07-04
EP2400302A1 (en) 2011-12-28

Similar Documents

Publication Publication Date Title
CN102326082A (zh) 凝固蛋白原原料及其制造方法、使用它测定来自生物的生理活性物质的方法和测定装置
CN101903776B (zh) 内毒素的测定方法和内毒素的测定用试剂盒
CN102869976B (zh) 凝胶粒子测定装置
CN104459139B (zh) 一种利用表面官能团的d二聚体乳胶增强免疫比浊检测试剂盒
US4038147A (en) Method for detecting endotoxins
CN101918840B (zh) 检测对象的检测方法和定量方法
JP5629306B2 (ja) 生物由来の生理活性物質の測定方法及び測定用試薬キット
WO2009148132A1 (ja) 生物由来の生理活性物質の測定方法、生物由来の生理活性物質の測定用キット及び、生物由来の生理活性物質の測定装置
CN103168243B (zh) 凝胶粒子测定试剂及使用其的测定方法
JP5096166B2 (ja) 生体サンプル中の微生物を分類する方法
WO2010092950A1 (ja) 生物由来の生理活性物質の測定方法及び測定装置
WO2013062013A1 (ja) 生物由来の生理活性物質の測定方法及び、それに用いられる微粒子及び抽出液
JP2012215461A (ja) 生物由来の生理活性物質の測定方法及び測定装置
HK1163805A (en) Coagulogen raw material, process for producing same, and method and apparatus for measuring physiologically active substance of biological origin using the same
JP3822974B2 (ja) エンドトキシン特異的ライセートの製造方法
JP2012154815A (ja) 生物由来の生理活性物質の測定方法及び測定装置
JP2007240397A (ja) （１→３）−β−Ｄ−グルカンの測定方法
JPWO2013168695A1 (ja) ヒアルロン酸製剤中の生物由来の生理活性物質の測定方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1163805

Country of ref document: HK

AD01 Patent right deemed abandoned

Effective date of abandoning: 20120118

C20 Patent right or utility model deemed to be abandoned or is abandoned
REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1163805

Country of ref document: HK