CN102241772B - 抗体与诊断试剂盒 - Google Patents
抗体与诊断试剂盒 Download PDFInfo
- Publication number
- CN102241772B CN102241772B CN201110126050.0A CN201110126050A CN102241772B CN 102241772 B CN102241772 B CN 102241772B CN 201110126050 A CN201110126050 A CN 201110126050A CN 102241772 B CN102241772 B CN 102241772B
- Authority
- CN
- China
- Prior art keywords
- antibody
- brca1
- terminal
- immune response
- albumen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Description
Claims (1)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33375210P | 2010-05-12 | 2010-05-12 | |
US61/333,752 | 2010-05-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102241772A CN102241772A (zh) | 2011-11-16 |
CN102241772B true CN102241772B (zh) | 2017-03-15 |
Family
ID=44913886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201110126050.0A Active CN102241772B (zh) | 2010-05-12 | 2011-05-12 | 抗体与诊断试剂盒 |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN102241772B (zh) |
WO (1) | WO2011140827A1 (zh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9476095B2 (en) | 2011-04-15 | 2016-10-25 | The Johns Hopkins University | Safe sequencing system |
EP3447495B2 (en) | 2012-10-29 | 2024-03-13 | The Johns Hopkins University | Papanicolaou test for ovarian and endometrial cancers |
US11286531B2 (en) | 2015-08-11 | 2022-03-29 | The Johns Hopkins University | Assaying ovarian cyst fluid |
CN105238763A (zh) * | 2015-10-26 | 2016-01-13 | 无锡傲锐东源生物科技有限公司 | 抗pr蛋白单克隆抗体杂交瘤细胞及其产生的抗pr单克隆抗体和应用 |
CN110927387B (zh) * | 2019-11-08 | 2022-05-20 | 江苏大学 | 一种brca2蛋白酶联免疫双抗夹心试剂盒及其应用 |
CN111253483B (zh) * | 2020-03-02 | 2021-07-30 | 江苏莱森生物科技研究院有限公司 | 一种抗brca1单克隆抗体及其用途 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1006181A2 (en) * | 1998-12-01 | 2000-06-07 | Affymetrix, Inc. (a California Corporation) | Expression monitoring of downstream genes in the BRCAl Pathway |
US7465540B2 (en) * | 2000-09-21 | 2008-12-16 | Luminex Corporation | Multiple reporter read-out for bioassays |
-
2011
- 2011-05-12 CN CN201110126050.0A patent/CN102241772B/zh active Active
- 2011-05-12 WO PCT/CN2011/000833 patent/WO2011140827A1/zh active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1006181A2 (en) * | 1998-12-01 | 2000-06-07 | Affymetrix, Inc. (a California Corporation) | Expression monitoring of downstream genes in the BRCAl Pathway |
US7465540B2 (en) * | 2000-09-21 | 2008-12-16 | Luminex Corporation | Multiple reporter read-out for bioassays |
Non-Patent Citations (3)
Title |
---|
BRCA1 gene expression in breast cancer A correlative study between real-time RT-PCR and immunohistochemistry;Fahd Al-Mulla et al;《Journal of Histochemistry & Cytochemistry》;20050501;第622页表1 * |
Detecting BRCA2 Protein Truncation in Tissue Biopsies to Identify Breast Cancers That Arise in BRCA2 Gene Mutation Carriers;Patrice Watson et al;《JOURNAL of ClLINICAL ONCOLOGY》;20090820;摘要 * |
Phosphorylated BRCA1 is predominantly located in the nucleus and mitochondri;Elisabeth D. Coene et al;《Molecular Biology of the Cell》;20050828;第998页第二栏第一段 * |
Also Published As
Publication number | Publication date |
---|---|
CN102241772A (zh) | 2011-11-16 |
WO2011140827A1 (zh) | 2011-11-17 |
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Address after: 313299 Zhejiang city of Huzhou province Deqing County Wukang Changhong Street No. 345 Applicant after: Zhejiang Shuo Wen Bioisystech Co., Ltd Address before: 304, room 345, office building, 313200 Changhong East Street, Zhejiang, Deqing County Applicant before: Huzhou Shuwen Biotechnologies Co., Ltd. |
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Free format text: CORRECT: APPLICANT; FROM: HUZHOU SHUWEN BIOTECHNOLOGIES CO., LTD. TO: ZHEJIANG SHUWEN BIO-TECHNOLOGIES CO., LTD. Free format text: CORRECT: ADDRESS; FROM: 313200 HUZHOU, ZHEJIANG PROVINCE TO: 313299 HUZHOU, ZHEJIANG PROVINCE |
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Effective date of registration: 20180816 Address after: 242000 19-2 buildings and 19-1 buildings of R & D building of Xuancheng science and Technology Park, Anhui economic and Technological Development Zone. Patentee after: Digital Biotechnology (Xuancheng) Co., Ltd. Address before: 313299 Changhong East Street, Wu Kang Town, Deqing County, Huzhou, Zhejiang 345 Patentee before: Zhejiang Shuo Wen Bioisystech Co., Ltd |
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