CN102170888B - 芍药苷制剂及其用于减少脂肪的用途 - Google Patents

芍药苷制剂及其用于减少脂肪的用途 Download PDF

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Publication number
CN102170888B
CN102170888B CN2009801251269A CN200980125126A CN102170888B CN 102170888 B CN102170888 B CN 102170888B CN 2009801251269 A CN2009801251269 A CN 2009801251269A CN 200980125126 A CN200980125126 A CN 200980125126A CN 102170888 B CN102170888 B CN 102170888B
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fat
preparation
fat splitting
peoniflorin
strengthens
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Expired - Fee Related
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CN2009801251269A
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CN102170888A (zh
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贝克尔·拉比耶
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0452—Specially adapted for transcutaneous muscle stimulation [TMS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0004—Applications of ultrasound therapy
    • A61N2007/0008—Destruction of fat cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN2009801251269A 2008-05-23 2009-05-25 芍药苷制剂及其用于减少脂肪的用途 Expired - Fee Related CN102170888B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/126,246 US7943187B2 (en) 2008-05-23 2008-05-23 Paeoniflorin preparations and uses thereof for fat reduction
US12/126,246 2008-05-23
PCT/CN2009/000569 WO2010127470A1 (en) 2008-05-23 2009-05-25 Paeoniflorin preparations and uses thereof for fat reduction

Publications (2)

Publication Number Publication Date
CN102170888A CN102170888A (zh) 2011-08-31
CN102170888B true CN102170888B (zh) 2013-06-19

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CN2009801251269A Expired - Fee Related CN102170888B (zh) 2008-05-23 2009-05-25 芍药苷制剂及其用于减少脂肪的用途

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Country Link
US (4) US7943187B2 (enExample)
EP (1) EP2300018B1 (enExample)
JP (1) JP5507549B2 (enExample)
KR (1) KR101656536B1 (enExample)
CN (1) CN102170888B (enExample)
AU (2) AU2009345773A1 (enExample)
CA (1) CA2725972A1 (enExample)
DK (1) DK2300018T3 (enExample)
WO (1) WO2010127470A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7943187B2 (en) * 2008-05-23 2011-05-17 Bakr Rabie Paeoniflorin preparations and uses thereof for fat reduction
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
US20130012840A1 (en) * 2010-03-23 2013-01-10 Real Aesthetics Ltd. System and method for accelerating the relative proportion of fat catabolism
US20120237492A1 (en) 2011-02-18 2012-09-20 Kythera Biopharmaceuticals, Inc. Treatment of submental fat
AU2014340351B2 (en) 2013-10-21 2020-01-30 Alevere Medical Corporation Fused heterocyclic organic compounds, pharmaceutical compositions, and medical uses thereof
US20170119794A1 (en) * 2015-11-04 2017-05-04 Kythera Biopharmaceuticals, Inc. Treatments of accumulated fat with deoxycholic acid and salts thereof
US20200397820A1 (en) 2018-02-09 2020-12-24 Kohaku Bio Technology Co., Ltd. Glycerol Release Promoter
KR102392292B1 (ko) 2021-07-21 2022-05-03 중앙대학교 산학협력단 페오니플로린을 포함하는 악액질 및 근손실 예방 또는 치료용 조성물

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2560367Y (zh) * 2001-08-30 2003-07-16 夏勤 适于喉部和气管滴入药物的针头
CN1555806A (zh) * 2003-12-31 2004-12-22 昆明同持医药研究有限公司 一种芍药甙注射剂及其制备方法和应用
CN1984637A (zh) * 2004-05-10 2007-06-20 株式会社Lg生活健康 包含芍药甙的皮肤老化护理品

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US5919621A (en) * 1991-10-24 1999-07-06 Brown; David B. Methods for diagnosing human male infertility
IL101387A (en) * 1992-03-26 1999-11-30 Pharmos Ltd Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets
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FR2717382B1 (fr) * 1994-03-21 1996-06-07 Fabre Pierre Cosmetique Extraits de Paeonia Lactiflora titré en paeoniflorine utiles en cosmétologie dans le traitement capillaire.
PE17897A1 (es) * 1995-02-17 1997-06-12 Lilly Co Eli Formulacion transdermica en parche del 3-(4-butiltio)-1,2,5-tiadiazol-3-il)-1-azabiciclo (2,2,2) octano
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KR100769580B1 (ko) * 2005-03-07 2007-10-23 주식회사 엘지생활건강 자외선에 의한 피부 ｄｎａ 손상 방지제
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CN2560367Y (zh) * 2001-08-30 2003-07-16 夏勤 适于喉部和气管滴入药物的针头
CN1555806A (zh) * 2003-12-31 2004-12-22 昆明同持医药研究有限公司 一种芍药甙注射剂及其制备方法和应用
CN1984637A (zh) * 2004-05-10 2007-06-20 株式会社Lg生活健康 包含芍药甙的皮肤老化护理品

Also Published As

Publication number Publication date
JP2011523950A (ja) 2011-08-25
KR20110138322A (ko) 2011-12-27
US20150018906A1 (en) 2015-01-15
US20170216333A1 (en) 2017-08-03
US7943187B2 (en) 2011-05-17
CN102170888A (zh) 2011-08-31
US20110218163A1 (en) 2011-09-08
HK1159477A1 (en) 2012-08-03
WO2010127470A1 (en) 2010-11-11
US9901591B2 (en) 2018-02-27
EP2300018A1 (en) 2011-03-30
US20170368086A9 (en) 2017-12-28
AU2015242976A1 (en) 2015-11-05
US20090292238A1 (en) 2009-11-26
CA2725972A1 (en) 2010-11-11
EP2300018A4 (en) 2011-07-20
JP5507549B2 (ja) 2014-05-28
DK2300018T3 (en) 2017-09-11
US8491947B2 (en) 2013-07-23
EP2300018B1 (en) 2017-05-17
KR101656536B1 (ko) 2016-09-12
AU2009345773A1 (en) 2010-11-11

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