CN102133334A - Preparation method of compound fructus broussonetiae preparation and application thereof - Google Patents
Preparation method of compound fructus broussonetiae preparation and application thereof Download PDFInfo
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- CN102133334A CN102133334A CN2011100600401A CN201110060040A CN102133334A CN 102133334 A CN102133334 A CN 102133334A CN 2011100600401 A CN2011100600401 A CN 2011100600401A CN 201110060040 A CN201110060040 A CN 201110060040A CN 102133334 A CN102133334 A CN 102133334A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
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Abstract
The invention belongs to the technical field of research and development of medical products and relates to a preparation method of compound fructus broussonetiae preparation and application thereof. The preparation method comprises the following steps: selecting and cleaning 10g-15g of fructus broussonetiae, 10g-15g of codonopsis pilosula, 10g-15g of lucid ganoderma, 5g-10g of raidx astragali, 5g-10g of rhizoma polygonati, 5g-10g of radix polygonati officinalis, 5g-10g of medlar, 5g-10g of herba epimedii and 3g-5g of liquorice, microwave drying the materials, and crushing the materials into powder with 50meshes; adding water in the powder and boiling and extracting the powder for three times, combining extracts, and filtering the extracts so as to obtain filtrate; concentrating the filtrate into an extract, mixing the extract and starch according to the proportion of 1:4, pelleting the mixture by using a sieve being 10mehses, drying particles, and then sieving the particles by a sieve being 14 meshes; and finally obtaining the compound fructus broussonetiae preparation. The compound fructus broussonetiae preparation can promote the growth of paralichthys olivaceus, and is beneficial to industrial production.
Description
Technical field
Medical product research and development technical field under the present invention.The present invention relates to a kind of preparation method and its usage of compound recipe Fructus Broussonetiae preparation.Product of the present invention has the Paralichthys olivaceus of promotion growth effect, and product of the present invention is beneficial to suitability for industrialized production.
Background technology
Advantage such as that Chinese herbal feed additive has is natural, economic, efficient, noresidue, no Drug resistance and side effect are little, and have the dual function of medical and trophism concurrently, the drawback of no antibiotics and chemicals, be widely used in recent years in the aquaculture of aquatic animal, in order to prevent disease, growth promotion with improve aquatic product quality.Contain multiple nutritional components and bioactive substances such as polysaccharide, aminoacid, protein, organic acid, tannin, alkaloid, flavone, glycoside, inorganic salt in the Chinese traditional compound medicine, can promote the synthetic of animal body metabolism and protein and enzyme, the scalable immunity function of animal is accelerated the speed of growth.Therefore mainly can to improve the animal body immunologic function relevant with it to it is generally acknowledged Chinese herbal medicine prevent disease and growth promoting function.
Paralichthys olivaceus Paralichthys olivaceus (Temminck et schlegel) is commonly called as tooth sheet, step, flatfish in China, is famous and precious seafood fish, is again one of important marine culture and stock enhancement Fish.It individual very large, fine and tender taste is delicious, is the first-class material of doing raw fish, is well received by consumers, market is very wide, economic worth is very high.Paralichthys olivaceus occupies certain status on the fishery history of China, but nearly 20-30, because overfishing and environmental pollution, cause natural resources to descend significantly, imbalance between supply and demand occurs, impelled people to move towards to culture road, in cultured fishes, be only second to snapper and cabrilla, in numerous aquatic products, Paralichthys olivaceus becomes new lover in the seafood family with characteristics such as its voluptuousness exquisiteness, delicious flavour, nutritive value height.The raw fish of edible Paralichthys olivaceus has become a kind of fashion, and supply falls short of demand for the requirement of market live fish, is more promising breed variety.Product of the present invention has the Paralichthys olivaceus of promotion growth effect, and product of the present invention is beneficial to suitability for industrialized production.
Summary of the invention
1, a kind of preparation method of compound recipe Fructus Broussonetiae preparation is characterized in that the preparation method of said preparation comprises following process:
Step (one): select high-quality Fructus Broussonetiae 10g-15g, Radix Codonopsis 10g-15g, Ganoderma 10g-15g, Radix Astragali 5g-10g, Rhizoma Polygonati 5g-10g, Rhizoma Polygonati Odorati 5g-10g, Fructus Lycii 5g-10g, Herba Epimedii 5g-10g, Radix Glycyrrhizae 3g-5g and clean, microwave drying, pulverizing are 50 order powder;
Step (two): the powder in the step () is added water boil extract 3 times, add 6-8 times of water gaging first and soak 4.0h-6.0h, heated and boiled is extracted 2.0h-3.0h, add for the second time 4 times of water gaging heated and boiled and extract 1.5h-2.0h, add 3 times of water gaging heated and boiled for the third time and extract 1.0h-1.5h, merge extractive liquid, filters, and gets filtrate;
Step (three): the filtrate in the step (two) is condensed into extractum, in extractum: starch=1: 4 ratio mixing, to granulate with 10 mesh sieves, the oven dry back is crossed 14 mesh sieves and is promptly got compound recipe Fructus Broussonetiae preparation.
2, the purposes of a kind of compound recipe Fructus Broussonetiae preparation as claimed in claim 1 is characterised in that it has the Paralichthys olivaceus of promotion growth effect.
According to the present invention, " % " among the present invention is percentage by weight.
The specific embodiment
The preparation method and its usage that relates to a kind of compound recipe Fructus Broussonetiae preparation of the present invention comprises following examples, and the following examples can further specify the present invention, but do not limit the present invention in any way.
Embodiment 1:
Step (one): select high-quality Fructus Broussonetiae 10g, Radix Codonopsis 10g, Ganoderma 10g, Radix Astragali 5g, Rhizoma Polygonati 5g, Rhizoma Polygonati Odorati 5g, Fructus Lycii 5g, Herba Epimedii 5g, Radix Glycyrrhizae 3g and clean, microwave drying, pulverizing is 50 order powder;
Step (two): the powder in the step () is added water boil extract 3 times, add 6 times of water gagings first and soak 4.0h, heated and boiled is extracted 2.0h, add for the second time 4 times of water gaging heated and boiled and extract 1.5h, add 3 times of water gaging heated and boiled for the third time and extract 1.0h, merge extractive liquid,, filter, get filtrate;
Step (three): the filtrate in the step (two) is condensed into extractum, in extractum: starch=1: 4 ratio mixing, to granulate with 10 mesh sieves, the oven dry back is crossed 14 mesh sieves and is promptly got compound recipe Fructus Broussonetiae preparation.
Embodiment 2:
Step (one): select high-quality Fructus Broussonetiae 15g, Radix Codonopsis 15g, Ganoderma 15g, Radix Astragali 10g, Rhizoma Polygonati 10g, Rhizoma Polygonati Odorati 10g, Fructus Lycii 10g, Herba Epimedii 10g, Radix Glycyrrhizae 5g and clean, microwave drying, pulverizing is 50 order powder;
Step (two): the powder in the step () is added water boil extract 3 times, add 8 times of water gagings first and soak 6.0h, heated and boiled is extracted 3.0h, add for the second time 4 times of water gaging heated and boiled and extract 2.0h, add 3 times of water gaging heated and boiled for the third time and extract 1.5h, merge extractive liquid,, filter, get filtrate;
Step (three): the filtrate in the step (two) is condensed into extractum, in extractum: starch=1: 4 ratio mixing, to granulate with 10 mesh sieves, the oven dry back is crossed 14 mesh sieves and is promptly got compound recipe Fructus Broussonetiae preparation.
Pharmacological evaluation
Compound recipe Fructus Broussonetiae preparation promotes Paralichthys olivaceus growth effect test
1 materials and methods
1.1 material
1.1.1 the preparation of compound recipe Fructus Broussonetiae preparation
Select high-quality Fructus Broussonetiae 10g, Radix Codonopsis 10g, Ganoderma 10g, Radix Astragali 5g, Rhizoma Polygonati 5g, Rhizoma Polygonati Odorati 5g, Fructus Lycii 5g, Herba Epimedii 5g, Radix Glycyrrhizae 3g and clean, microwave drying, pulverizing is 50 order powder; Powder is added water boil extract 3 times, add 6 times of water gagings first and soak 4.0h, heated and boiled extraction 2.0h adds 4 times of water gaging heated and boiled for the second time and extracts 1.5h, adds 3 times of water gaging heated and boiled for the third time and extracts 1.0h, and merge extractive liquid, filters, and gets filtrate; Filtrate is condensed into extractum, in extractum: starch=1: 4 ratio mixing, to granulate with 10 mesh sieves, the oven dry back is crossed 14 mesh sieves and is promptly got compound recipe Fructus Broussonetiae preparation.
1.1.2 foundation bait
Prescription is fish and shrimp powder 30%, bean cake 30%, flour 25.6%, yeast powder 5%, Oleum Glycines 5%, soybean lecithin 1.5%, carbonic acid calcium dihydrogen 1%, sodium alginate 0.5%, choline chloride 0.5%, mixed vitamin 0.5%, mixed inorganic 0.4%, wherein crude protein 44.7%, and crude fat 3.9% is done blank with foundation bait.
1.1.3 the preparation of compound recipe Fructus Broussonetiae preparation test feed
With compound recipe Fructus Broussonetiae preparation: the ratio of foundation bait=1: 9 is made compound recipe Fructus Broussonetiae test feed.
1.1.4 test Paralichthys olivaceus and feeding and management thereof
Test used Paralichthys olivaceus body weight (8.30 ± 0.90) g, long (10.63 ± 0.77) cm of body, male and female are all used.Supported temporarily before on-test in indoor glass aquarium, with foundation bait it is satiated with food and throws something and feeds, test water is the sea water of aeration aerating 24h.Keep dissolved oxygen in water amount 5.0mg/L, water temperature is controlled at (23 ± 1) ℃, raises and train to begin experiment after 7 days.
By the body weight random packet, test group is thrown something and fed with compound recipe Fructus Broussonetiae preparation test feed with Paralichthys olivaceus in test, the matched group normal feedstuff of throwing something and feeding, every group 20 tail, establish three parallel.Every other day experimental period, feeding volume was 1.5%～2% of fish body constitution amount, and regularly throw something and feed during 7:00 and during 19:00 every day, and the test period is 15 big.
1.2 method
1.2.1 compound recipe Fructus Broussonetiae preparation is measured the facilitation and the feed coefficient of Paralichthys olivaceus body weight
The test initial stage is measured length of fish body and fish body weight, and record, during off-test, length of fish body and fish body weight is measured again.Collect the Excreta and the erbium material residue of test color simultaneously, weigh after the oven dry.The matched group fish is raised the same test group of condition, throws something and feeds foundation bait in contrast.
Rate of body weight gain=[(testing last fish body counterpoise-test fish body counterpoise just)/test is fish body counterpoise just] * 100%
Feed coefficient=(bait consumption/fish body weight gains amount) * 100%.
1.2.2 compound recipe Fructus Broussonetiae preparation is to the mensuration of Paralichthys olivaceus coefficient of condition influence
Coefficient of condition (%)=(test last fish body weight/test last length of fish body) * 100%
1.2.3 compound recipe Fructus Broussonetiae preparation is to the mensuration of Paralichthys olivaceus liver body than influence
Test group and matched group are all raised by daily mode.Randomly draw 6 of experiment fishes from each group during on-test, put to death the back of weighing, and dissects along cloacal aperture, and clip liver pancreas is also weighed.Take identical operations during off-test.Liver body ratio=(testing the last fish body weight of last fish body liver weight/test) * 100%
2 results
Compound recipe Fructus Broussonetiae preparation is to the result that influences of Paralichthys olivaceus growth indexes
See Table 1.
Table 1 compound recipe Fructus Broussonetiae preparation is to the result that influences of Paralichthys olivaceus growth indexes
Annotate: compare P＜0.05 with matched group
As shown in Table 1, rate of body weight gain, coefficient of condition, the liver body of compound recipe Fructus Broussonetiae preparation test feed are higher than matched group than generally, and feed coefficient is lower than matched group.
Claims (2)
1. the preparation method of a compound recipe Fructus Broussonetiae preparation is characterized in that the preparation method of said preparation comprises following process:
Step (one): select high-quality Fructus Broussonetiae 10g-15g, Radix Codonopsis 10g-15g, Ganoderma 10g-15g, Radix Astragali 5g-10g, Rhizoma Polygonati 5g-10g, Rhizoma Polygonati Odorati 5g-10g, Fructus Lycii 5g-10g, Herba Epimedii 5g-10g, Radix Glycyrrhizae 3g-5g and clean, microwave drying, pulverizing are 50 order powder;
Step (two): the powder in the step () is added water boil extract 3 times, add 6-8 times of water gaging first and soak 4.0h-6.0h, heated and boiled is extracted 2.0h-3.0h, add for the second time 4 times of water gaging heated and boiled and extract 1.5h-2.0h, add 3 times of water gaging heated and boiled for the third time and extract 1.0h-1.5h, merge extractive liquid, filters, and gets filtrate;
Step (three): the filtrate in the step (two) is condensed into extractum, in extractum: starch=1: 4 ratio mixing, to granulate with 10 mesh sieves, the oven dry back is crossed 14 mesh sieves and is promptly got compound recipe Fructus Broussonetiae preparation.
2. the purposes of a kind of compound recipe Fructus Broussonetiae preparation as claimed in claim 1 is characterised in that it has the Paralichthys olivaceus of promotion growth effect.
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| CN2011100600401A CN102133334B (en) | 2011-03-08 | 2011-03-08 | Preparation method of compound fructus broussonetiae preparation and application thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102488320A (en) * | 2011-12-08 | 2012-06-13 | 江苏中烟工业有限责任公司 | Application of paper mulberry fruit essential oil in cigarette flavoring and material feeding |
| CN103585097A (en) * | 2013-11-29 | 2014-02-19 | 广州市娇兰化妆品有限公司 | Epidermal growth factor-loaded bletilla rhizome polysaccharide compound, and preparation method and application thereof |
| CN103989745A (en) * | 2014-05-12 | 2014-08-20 | 南京中医药大学 | A paper mulberry fruit extract product with anti-hepatoma activity and an extraction method thereof |
| CN104543456A (en) * | 2014-12-12 | 2015-04-29 | 青岛无为保温材料有限公司 | Paralichthys olivaceus Chinese herbal medicine attractant and preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1698724A (en) * | 2005-04-08 | 2005-11-23 | 中国海洋大学 | Compound Chinese herbal immunopotentiator for juvenile of paralichthys olivaceus |
| CN101828643A (en) * | 2010-05-10 | 2010-09-15 | 大连水产学院 | Chinese medicinal herb feed additive for enhancing immunity of paralichthys olivaceus |
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2011
- 2011-03-08 CN CN2011100600401A patent/CN102133334B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1698724A (en) * | 2005-04-08 | 2005-11-23 | 中国海洋大学 | Compound Chinese herbal immunopotentiator for juvenile of paralichthys olivaceus |
| CN101828643A (en) * | 2010-05-10 | 2010-09-15 | 大连水产学院 | Chinese medicinal herb feed additive for enhancing immunity of paralichthys olivaceus |
Non-Patent Citations (2)
| Title |
|---|
| 《水产学报》 20060228 王吉桥等 金银花等复方草药对牙鲆生长、消化和免疫能力的影响 90-96 1-2 , 第01期 2 * |
| 《渔业现代化》 20010430 常忠岳等 工厂化养殖牙鲆生长及成活因素探讨 24-25、29 1-2 , 第02期 2 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102488320A (en) * | 2011-12-08 | 2012-06-13 | 江苏中烟工业有限责任公司 | Application of paper mulberry fruit essential oil in cigarette flavoring and material feeding |
| CN103585097A (en) * | 2013-11-29 | 2014-02-19 | 广州市娇兰化妆品有限公司 | Epidermal growth factor-loaded bletilla rhizome polysaccharide compound, and preparation method and application thereof |
| CN103989745A (en) * | 2014-05-12 | 2014-08-20 | 南京中医药大学 | A paper mulberry fruit extract product with anti-hepatoma activity and an extraction method thereof |
| CN104543456A (en) * | 2014-12-12 | 2015-04-29 | 青岛无为保温材料有限公司 | Paralichthys olivaceus Chinese herbal medicine attractant and preparation method |
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| CN102133334B (en) | 2012-04-18 |
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