CN102138647B - Method for preparing compound ginseng preparation and application thereof - Google Patents

Method for preparing compound ginseng preparation and application thereof Download PDF

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Publication number
CN102138647B
CN102138647B CN2011100078093A CN201110007809A CN102138647B CN 102138647 B CN102138647 B CN 102138647B CN 2011100078093 A CN2011100078093 A CN 2011100078093A CN 201110007809 A CN201110007809 A CN 201110007809A CN 102138647 B CN102138647 B CN 102138647B
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grams
preparation
compound ginseng
extract
ginseng preparation
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CN102138647A (en
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张崇禧
刘铁铮
田芯
张岩
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Shandong University Weihai
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Shandong University Weihai
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish
    • Y02A40/818Alternative feeds for fish, e.g. in aquacultures
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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Abstract

The invention belongs to the technical field of the research and development of medicine products, and relates to a method for preparing a compound ginseng preparation and application thereof. The method comprises the following steps of: selecting the following components: 6 to 9 grams of ginseng, 6 to 9 grams of astragalus, 3 to 6 grams of eucommia bark, 3 to 6 grams of glossy ganoderma, 3 to 6 grams of Chinese angelica, 2 to 4 grams of leonurus, 2 to 4 grams of tangerine peel, 1 to 2 grams of Indian buead, 1 to 2 grams of hawthorn fruit, 1 to 2 grams of medicated leaven and 1 to 2 grams of liquoric root, cleaning, performing microwave drying, and crushing to form 50-mesh powder; adding water, boiling, extracting for three times, merging extract, and filtering to obtain filter liquor; and concentrating the filter liquor to form extractum, mixing the extractum, agar and starch in a ratio of 4:1:16 uniformly, pelletizing by using a 10-mesh sieve, drying, and sieving with a 14-mesh sieve to obtain the compound ginseng preparation. The compound ginseng preparation has the promoting effect on the growth of fancy carps and is favorable for industrial production.

Description

A kind of preparation method and its usage of compound ginseng preparation
Technical field
Medical product research and development technical field under the present invention.The present invention relates to a kind of preparation method and its usage of compound ginseng preparation.Product of the present invention has facilitation to fancy carp growth, and product of the present invention is beneficial to suitability for industrialized production.
Background technology
Advantage such as that Chinese herbal feed additive has is natural, economic, efficient, noresidue, the no resistance to the action of a drug and side effect are little; And have the double action of medical and trophism concurrently; The drawback of no antibiotic and chemicals; Be widely used in recent years in the aquaculture of aquatic animal, in order to prevent disease, growth promotion with improve aquatic product quality.Contain the various active composition in the Chinese herbal medicine, the scalable immunity function of animal.Therefore it is generally acknowledged Chinese herbal medicine prevent disease and growth promoting function, main can to improve the animal body immunologic function relevant with it.The feed addictive of fish has shortcomings such as the thawing of being prone to, poor stability at present, and a part can not be eaten by fish, and utilization rate is low, and waste is serious.Agar (Agar) is claimed agar-agar again, is the hydrophilic macromolecule polysaccharide that from the Bostrychia montagnei guiding principle, extracts, and has good gelling and stability, be widely used in aspects such as food, medicine, bioengineering, but the application in the fish feed additive is not reported.
Summary of the invention
1, a kind of preparation method of compound ginseng preparation is characterized in that method of making preparation comprises following process:
Step (one): select high-quality genseng 6g-9g, Radix Astragali 6g-9g, bark of eucommia 3g-6g, glossy ganoderma 3g-6g, Radix Angelicae Sinensis 3g-6g, motherwort 2g-4g, dried orange peel 2g-4g, Poria cocos 1g-2g, hawthorn 1g-2g, Divine Comedy 1g-2g, Radix Glycyrrhizae 1g-2g and clean; Microwave drying, pulverizing are 50 order powder;
Step (two): the powder in the step () is added water boil extract 3 times; Add 6-8 times of water gaging first and soak 4.0h-6.0h, heated and boiled is extracted 2.0h-3.0h, adds 4 times of water gaging heated and boiled for the second time and extracts 1.5h-2.0h; Add 3 times of water gaging heated and boiled for the third time and extract 1.0h-1.5h; Merge extract, filter, must filtrate;
Step (three): the filtrating in the step (two) is condensed into medicinal extract, in medicinal extract: agar: starch=4: 1: 16 ratio mixings, to granulate with 10 mesh sieves, the oven dry back is crossed 14 mesh sieves and is promptly got the compound ginseng preparation.
2, the purposes of a kind of compound ginseng preparation as claimed in claim 1 is characterised in that it has facilitation to fancy carp growth.
According to the present invention, " % " among the present invention is percentage by weight.
The specific embodiment
The preparation method and its usage that relates to a kind of compound ginseng preparation of the present invention comprises following examples, and following embodiment can further specify the present invention, but does not limit the present invention in any way.
Embodiment 1:
Step (one): select high-quality genseng 6g, Radix Astragali 6g, bark of eucommia 3g, glossy ganoderma 3g, Radix Angelicae Sinensis 3g, motherwort 2g, dried orange peel 2g, Poria cocos 1g, hawthorn 1g, Divine Comedy 1g, Radix Glycyrrhizae 1g and clean, microwave drying, pulverizing are 50 order powder;
Step (two): the powder in the step () is added water boil extract 3 times, add 6 times of water gagings first and soak 4.0h, heated and boiled is extracted 2.0h; Add for the second time 4 times of water gaging heated and boiled and extract 1.5h, add 3 times of water gaging heated and boiled for the third time and extract 1.0h, merge extract; Filter, must filtrate;
Step (three): the filtrating in the step (two) is condensed into medicinal extract, in medicinal extract: agar: starch=4: 1: 16 ratio mixings, to granulate with 10 mesh sieves, the oven dry back is crossed 14 mesh sieves and is promptly got the compound ginseng preparation.
Embodiment 2:
Step (one): select high-quality genseng 9g, Radix Astragali 9g, bark of eucommia 6g, glossy ganoderma 6g, Radix Angelicae Sinensis 6g, motherwort 4g, dried orange peel 4g, Poria cocos 2g, hawthorn 2g, Divine Comedy 2g, Radix Glycyrrhizae 2g and clean, microwave drying, pulverizing are 50 order powder;
Step (two): the powder in the step () is added water boil extract 3 times, add 8 times of water gagings first and soak 6.0h, heated and boiled is extracted 3.0h; Add for the second time 4 times of water gaging heated and boiled and extract 2.0h, add 3 times of water gaging heated and boiled for the third time and extract 1.5h, merge extract; Filter, must filtrate;
Step (three): the filtrating in the step (two) is condensed into medicinal extract, in medicinal extract: agar: starch=4: 1: 16 ratio mixings, to granulate with 10 mesh sieves, the oven dry back is crossed 14 mesh sieves and is promptly got the compound ginseng preparation.
Pharmacological evaluation
The compound ginseng preparation promotes the experiment of fancy carp growth effect
1 materials and methods
1.1 material
1.1.1 compound ginseng preparation
Select high-quality genseng 9g, Radix Astragali 9g, bark of eucommia 6g, glossy ganoderma 6g, Radix Angelicae Sinensis 6g, motherwort 4g, dried orange peel 4g, Poria cocos 2g, hawthorn 2g, Divine Comedy 2g, Radix Glycyrrhizae 2g and clean, microwave drying, pulverizing are 50 order powder; Powder is added water boil extract 3 times, add 8 times of water gagings first and soak 6.0h, heated and boiled is extracted 3.0h; Add for the second time 4 times of water gaging heated and boiled and extract 2.0h, add 3 times of water gaging heated and boiled for the third time and extract 1.5h, merge extract; Filter, must filtrate, filtrating is condensed into medicinal extract; In medicinal extract: agar: starch=4: 1: 16 ratio mixings, to granulate with 10 mesh sieves, the oven dry back is crossed 14 mesh sieves and is promptly got the compound ginseng preparation.
1.1.2 experiment feed
By the compound ginseng preparation: the mixed uniform preparation of basal feed=3: 5 is done blank for compound ginseng preparation experiment feed with basal feed.The basal feed prescription is used in experiment, sees table 1.
Table 1 experiment is filled a prescription with basal feed
Figure BSA00000419892400031
1.2 method
1.2.1 experiment is raised with bright and beautiful carp
Experiment with bright and beautiful carp Cyprinus carpio L. available from aquatic products market, Weihai, body weight (41.1 ± 5.0) g, long (10.27 ± 0.48) Gm of body, the male and female dual-purpose, experiment is supported in indoor glass aquarium before beginning temporarily, with commercial feed it is satiated with food and throws something and feeds.As source of recycled water, 24h continues aeration aerating, keeps dissolved oxygen in water amount 5.0mg/L with the running water of abundant aeration dechlorination, and water temperature is controlled at (21 ± 1) ℃, begins to test after raising and train 7d.Experiment is divided into 2 groups with bright and beautiful carp by body weight at random, and experimental group is tested feedstuff feeding with the compound ginseng preparation, the control group basal feed of throwing something and feeding, every group 20 tail, establish 3 parallel.Experimental period every other day feeding volume is 2%~3% of a fish physique amount, and regularly throw something and feed during 7:00 and during 19:00 every day, and be 15 days experimental period.
1.2.2 the compound ginseng preparation is to the facilitation of bright and beautiful carp body weight and the mensuration of feed coefficient
The experiment initial stage is measured length of fish body and fish body weight, and record, when experiment finishes, length of fish body and fish body weight is measured again.Collect excreta and the bait residue of experiment fish simultaneously, weigh after the oven dry.The control group fish is raised the same experimental group of condition, and the foundation bait of throwing something and feeding is as contrast.
Rate of body weight gain=[(testing last fish body counterpoise-experiment fish body counterpoise just)/experiment is fish body counterpoise just] * 100%
Feed coefficient=(bait consumption/fish body weight gains amount) * 100%.
1.2.3 the compound ginseng preparation is to the mensuration of bright and beautiful carp richness influence
Richness (%)=(test last fish body weight/test last length of fish body) * 100%
1.2.4 the compound ginseng preparation is to the mensuration of bright and beautiful carp liver body than influence
Experimental group and control group are all raised by daily mode.Randomly draw 6 of experiment fishes from each group during the experiment beginning, put to death the back of weighing, and dissects along cloacal aperture, and the clip liver is also weighed.When finishing, experiment takes identical operations.Liver body ratio=(testing the last fish body weight of last fish body liver weight/experiment) * 100%.
2 results
The compound ginseng preparation promotes the result of fancy carp growth effect
See table 2.
Table 2 compound ginseng preparation promotes the result of fancy carp growth effect
Figure BSA00000419892400041
Annotate: compare * P<0.05 with control group
Visible by table 2, the compound ginseng preparation can significantly improve rate of body weight gain, coefficient of condition, the liver body ratio of bright and beautiful carp, and can reduce feed coefficient.

Claims (2)

1. the preparation method of a compound ginseng preparation is characterized in that method of making preparation comprises following process:
Step (one): select high-quality genseng 6g-9g, Radix Astragali 6g-9g, bark of eucommia 3g-6g, glossy ganoderma 3g-6g, Radix Angelicae Sinensis 3g-6g, motherwort 2g-4g, dried orange peel 2g-4g, Poria cocos 1g-2g, hawthorn 1g-2g, Divine Comedy 1g-2g, Radix Glycyrrhizae 1g-2g and clean; Microwave drying, pulverizing are 50 order powder;
Step (two): the powder in the step () is added water boil extract 3 times; Add 6-8 times of water gaging first and soak 4.0h-6.0h, heated and boiled is extracted 2.0h-3.0h, adds 4 times of water gaging heated and boiled for the second time and extracts 1.5h-2.0h; Add 3 times of water gaging heated and boiled for the third time and extract 1.0h-1.5h; Merge extract, filter, must filtrate;
Step (three): the filtrating in the step (two) is condensed into medicinal extract, in medicinal extract: agar: starch=4: 1: 16 ratio mixings, to granulate with 10 mesh sieves, the oven dry back is crossed 14 mesh sieves and is promptly got the compound ginseng preparation.
2. the purposes of a kind of compound ginseng preparation of preparation method's preparation as claimed in claim 1 is characterised in that it has facilitation to fancy carp growth.
CN2011100078093A 2011-01-03 2011-01-03 Method for preparing compound ginseng preparation and application thereof Expired - Fee Related CN102138647B (en)

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CN102805257A (en) * 2012-07-24 2012-12-05 山东大学威海分校 Compound Chinese herbal medicine additive for promoting growth of aquatic products and using method thereof
CN102934761B (en) * 2012-12-06 2013-11-20 山东新希望六和集团有限公司 Feed for improving fish productivity and immunity

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CN1759718A (en) * 2003-12-23 2006-04-19 吴跃飞 Green sanitary aquatic products produced by using marine lives as bioreactor and method
CN1919036A (en) * 2005-05-23 2007-02-28 吴跃飞 Green health care animal foodstuff produced by living animal bioreactor and producing method thereof
CN101002591B (en) * 2006-01-16 2012-01-25 邵峰 Feed additive and feed therewith

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