CN102112483A - (2s,3r,4r,5s,6r)-2-(4-氯-3-(4-乙氧基苄基)苯基)-6-(甲基硫)四氢-2h-吡喃-3,4,5-三醇的固体形式及其使用方法 - Google Patents

(2s,3r,4r,5s,6r)-2-(4-氯-3-(4-乙氧基苄基)苯基)-6-(甲基硫)四氢-2h-吡喃-3,4,5-三醇的固体形式及其使用方法 Download PDF

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CN102112483A
CN102112483A CN2009801279245A CN200980127924A CN102112483A CN 102112483 A CN102112483 A CN 102112483A CN 2009801279245 A CN2009801279245 A CN 2009801279245A CN 200980127924 A CN200980127924 A CN 200980127924A CN 102112483 A CN102112483 A CN 102112483A
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chloro
crystalline compounds
phenyl
peak
pyrans
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苏珊·玛格丽特·德保罗
阿内特·佩尔贝格
赵芒柱
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Lexicon Pharmaceuticals Inc
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Lexicon Pharmaceuticals Inc
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CN2009801279245A 2008-07-17 2009-07-15 (2s,3r,4r,5s,6r)-2-(4-氯-3-(4-乙氧基苄基)苯基)-6-(甲基硫)四氢-2h-吡喃-3,4,5-三醇的固体形式及其使用方法 Pending CN102112483A (zh)

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CN201710477527.7A CN107629097A (zh) 2008-07-17 2009-07-15 一种化合物的固体形式及其使用方法

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US8142308P 2008-07-17 2008-07-17
US61/081,423 2008-07-17
PCT/US2009/050636 WO2010009197A1 (en) 2008-07-17 2009-07-15 Solid forms of (2s,3r,4r,5s,6r)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2h-pyran-3,4,5-triol and methods of their use

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CN201710477527.7A Withdrawn CN107629097A (zh) 2008-07-17 2009-07-15 一种化合物的固体形式及其使用方法

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WO2017202351A1 (zh) * 2016-05-25 2017-11-30 苏州科睿思制药有限公司 一种钠-葡萄糖协同转运蛋白抑制剂药物的新晶型及其制备方法和用途
CN110818722A (zh) * 2018-08-14 2020-02-21 苏州鹏旭医药科技有限公司 三种化合物及其制备方法和在合成索格列净中的用途
CN113880701A (zh) * 2021-10-10 2022-01-04 浙江司太立制药股份有限公司 一种抗糖尿病药物中间体及其制备方法

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AU2008279424B2 (en) 2007-07-26 2013-06-13 Lexicon Pharmaceuticals, Inc. Methods and compounds useful for the preparation of sodium glucose co-transporter 2 inhibitors
AU2009270936B2 (en) 2008-07-15 2014-12-18 Theracos, Inc. Deuterated benzylbenzene derivatives and methods of use
TWI472521B (zh) 2008-07-17 2015-02-11 Lexicon Pharmaceuticals Inc （２ｓ，３ｒ，４ｒ，５ｓ，６ｒ）－２－（４－氯－３－（４－乙氧苄基）苯基）－６－（甲硫）四氫－２ｈ－哌喃－３，４，５－三醇的固體形態與其使用方法
TWI562775B (en) * 2010-03-02 2016-12-21 Lexicon Pharmaceuticals Inc Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
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TWI631963B (zh) * 2011-01-05 2018-08-11 雷西肯製藥股份有限公司 包含鈉－葡萄糖共同輸送體１與２之抑制劑的組合物與應用方法
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US12213970B2 (en) 2018-10-29 2025-02-04 Boehringer Ingelheim International Gmbh Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof
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CN109824687B (zh) * 2019-03-26 2022-03-22 上海凌凯医药科技有限公司 呋喃木糖衍生物的新合成方法
KR102951944B1 (ko) * 2019-07-05 2026-04-10 산동 단홍 파머수티컬 컴퍼니., 리미티드. SGLTs 억제제의 결정형 및 그 응용
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Publication number Priority date Publication date Assignee Title
WO2017202351A1 (zh) * 2016-05-25 2017-11-30 苏州科睿思制药有限公司 一种钠-葡萄糖协同转运蛋白抑制剂药物的新晶型及其制备方法和用途
CN109195980A (zh) * 2016-05-25 2019-01-11 苏州科睿思制药有限公司 一种钠-葡萄糖协同转运蛋白抑制剂药物的新晶型及其制备方法和用途
CN109195980B (zh) * 2016-05-25 2022-05-17 苏州科睿思制药有限公司 一种钠-葡萄糖协同转运蛋白抑制剂药物的新晶型及其制备方法和用途
CN110818722A (zh) * 2018-08-14 2020-02-21 苏州鹏旭医药科技有限公司 三种化合物及其制备方法和在合成索格列净中的用途
CN110818722B (zh) * 2018-08-14 2022-12-02 苏州鹏旭医药科技有限公司 三种化合物及其制备方法和在合成索格列净中的用途
CN113880701A (zh) * 2021-10-10 2022-01-04 浙江司太立制药股份有限公司 一种抗糖尿病药物中间体及其制备方法

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IL210269A0 (en) 2011-03-31
US20100016422A1 (en) 2010-01-21
EP2332947A1 (en) 2011-06-15
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CL2009001595A1 (es) 2010-07-19
ZA201100175B (en) 2012-03-28
AR072807A1 (es) 2010-09-22
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US20130165395A1 (en) 2013-06-27
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DK2332947T3 (da) 2018-01-29
US8217156B2 (en) 2012-07-10
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CO6351797A2 (es) 2011-12-20
KR101707246B1 (ko) 2017-02-15
SG185317A1 (en) 2012-11-29
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NO2332947T3 (https=) 2018-03-31
IL210269A (en) 2015-06-30
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PL2332947T3 (pl) 2018-04-30
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