CN102085294A - Medicinal composition with immunoregulation effect - Google Patents
Medicinal composition with immunoregulation effect Download PDFInfo
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- CN102085294A CN102085294A CN2009102255678A CN200910225567A CN102085294A CN 102085294 A CN102085294 A CN 102085294A CN 2009102255678 A CN2009102255678 A CN 2009102255678A CN 200910225567 A CN200910225567 A CN 200910225567A CN 102085294 A CN102085294 A CN 102085294A
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Abstract
The invention discloses a medicinal composition with an immunoregulation effect, which is prepared from the raw medicinal materials including 8-15 parts of astragalus root, 3-10 parts of ginseng, 3-10 parts of garlic and 2-5 parts of liquorice. The medicinal composition is prepared by reasonably matching and combining different herbal medicines and has an obvious immunoregulation effect, and in addition, the herbal medicines are all conventional raw medicinal materials so that the advantages of good safety and no toxic and side effects are achieved.
Description
Technical field
The present invention relates to the pharmaceutical preparations technology field, especially a kind of pharmaceutical composition with immunoregulation effect.
Background technology
Immunomodulating is meant in the immunne response process between inner each cell of immune system, between immunocyte and the immune molecule and the interaction between immune system and the other system, constitute a network structure of coordination, mutual restriction mutually, make immunne response keep suitable intensity, thereby guarantee the stable of organismic internal environment.
Immunne response is as a kind of physiological function, no matter is the tolerance phenomenon to self component, all is to carry out under the control of immune regulation mechanism of body to " non-" antigenic repulsion still.Immune regulation mechanism is to keep the stable key of organismic internal environment, if immunoloregulation function is unusual, self component is produced intensive immune attack, causes cytoclasis, and autoimmune disease will take place afunction.If cause pathogeny imcrobe infection can not produce the reaction (reacted low and can make severe infections, reacted anaphylaxis then takes place by force) of appropriateness to external world, also can cause illeffects to body.Therefore, immune regulation mechanism has not only determined the generation of immunne response, and has determined the power of reaction.
Body's immunological function is usually with hyperfunction or hang down description, and is hyperfunction, lowly all be deleterious for body.The people's is whether healthy, depends on that body's immunological function keeps relative homeostasis, the i.e. relative equilibrium of immunologic function.
Sometimes immune system also can be broken not reacting self material, and the effect of oneself is repelled in appearance, then forms so-called autoimmune phenomena, if caused tissue injury, then autoimmune disease can take place, as rheumatoid arthritis, lupus erythematosus, rheumatoid heart disease etc.
When immune function of human body takes place unusually to causing obvious pathological changes, can influence the operate as normal life greatly, promptly need to give suitable immunoregulation medicament this moment, makes immune function of human body recover normal.
Summary of the invention
Main purpose of the present invention just provides a kind of new pharmaceutical composition with immunoregulation effect.
In order to realize the foregoing invention purpose, the technical solution used in the present invention is as follows:
A kind of pharmaceutical composition with immunoregulation effect, make with following amount amount part proportion raw material medicine:
Radix Astragali 8-15 part, Radix Ginseng 3-10 part, Bulbus Allii 3-10 part, Radix Glycyrrhizae 2-5 part.
The crude drug proportioning of aforementioned pharmaceutical compositions can be preferably:
Radix Astragali 10-12 part, Radix Ginseng 5-8 part, Bulbus Allii 5-8 part, Radix Glycyrrhizae 3-4 part.
Medicine of the present invention can be according to the conventional preparation method preparation of various peroral dosage form medicines.
In each crude drug of pharmaceutical composition of the present invention:
The Radix Astragali is the root of leguminous herbaceous plant's Radix Astagali, Radix Astragali.Mainly contain flavones ingredient calycosin (calycosin), 3-hydroxyl-9,10-dimethoxy Lignum pterocarpi indici alkane also contains astragaloside I, V, III compositions such as (astragaloside I, V, III).Have effects such as invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Be usually used in that the deficiency of vital energy is weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle are difficultly burst, burst for a long time do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst and chronic nephritis proteinuria, diabetes.
Radix Ginseng is the dry root of Araliaceae Radix Ginseng Panax ginseng C.A.Mey..Kind of ginsenoside surplus containing 30 (can be divided into three groups, be oleanolic acid group, protopanoxadiol group and Protopanaxatriol's group), be called ginsenoside (Ginsenoside)-RX (X=0, a1, a2, a3, b1, b2, b3, c, d, e, f, g1, g2, g3, h1, h2, h3, s1, s2), Panax pseudoginseng Wall. Saponin (Pseudoginsenoside saponin) F11 etc. is still arranged.Saponin is the material base of Radix Ginseng physiologically active.Protopanoxadiol (Protopanaxadiol) and Protopanaxatriol (Protopanaxatriol) are the former existence forms among the ginsenoside, when separating glycoside unit, because the effect of diluted acid, the hydroxyl and the ethylene linkage cyclization of molecular side chain part form panoxadiol (Panaxadiol) and panaxatriol (Panaxatriol), and panoxadiol and panaxatriol all are triterpenoid compound.Function: strongly invigorating primordial QI, take off and promote the production of body fluid, calm the nerves admittedly.Cure mainly: impairment caused by overstrain is deficient, lack of appetite, asthenia, regurgitation are told food, stool lingering diarrhea, empty cough with asthma are short, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency be multiple, the card of all qi-blood-body fluid deficiencies.Ginsenoside and ginseng polysaccharide have stimulation to intact animal's reticuloendothelial system phagocytic function.Ginsenoside or Flos Ginseng's Saponin can significantly strengthen the activate the phagocytic capacity of mouse peritoneal emigrated cell to chicken red blood cell.Ginseng polysaccharide or other compositions also have stimulation to intact animal's reticuloendothelial system.Therefore, Radix Ginseng also has significant immunoregulation effect.
Radix Glycyrrhizae is dicotyledon pulse family Leguminosae Radix Glycyrrhizae Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. G.inflata Bat., or the root and rhizome of Glycyrrhiza glabra L. G.glabra L..Have effects such as invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.But be usually used in the anxious pain of weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, and cushion toxicity and strong.
Compared with prior art, the invention has the beneficial effects as follows: pharmaceutical composition of the present invention is reasonably combined by different pharmaceutical, has tangible immunomodulating effect; And be crude drug commonly used, safety is good, has no side effect.
The specific embodiment
The present invention is described in further detail below in conjunction with the specific embodiment.
Embodiment 1
Present embodiment has the pharmaceutical composition of immunoregulation effect and makes with following amount amount part proportion raw material medicine:
15 parts of the Radixs Astragali, 10 parts of Radix Ginsengs, 3 parts in Bulbus Allii, 4 parts in Radix Glycyrrhizae.
Embodiment 2
Present embodiment has the pharmaceutical composition of immunoregulation effect and makes with following amount amount part proportion raw material medicine:
10 parts of the Radixs Astragali, 5 parts of Radix Ginsengs, 8 parts in Bulbus Allii, 2 parts in Radix Glycyrrhizae.
Embodiment 3
Present embodiment has the pharmaceutical composition of immunoregulation effect and makes with following amount amount part proportion raw material medicine:
8 parts of the Radixs Astragali, 8 parts of Radix Ginsengs, 10 parts in Bulbus Allii, 5 parts in Radix Glycyrrhizae.
Embodiment 4
Present embodiment has the pharmaceutical composition of immunoregulation effect and makes with following amount amount part proportion raw material medicine:
12 parts of the Radixs Astragali, 3 parts of Radix Ginsengs, 5 parts in Bulbus Allii, 3 parts in Radix Glycyrrhizae.
The various embodiments described above medicine is all by following method preparation: the crude drug of getting described ratio mixes, and adds 12 times of 70% alcohol reflux 5 hours, filters filtrate for later use; Filtering residue added 10 times of 70% alcohol reflux 3 hours again, filtered; Merge filtrate twice, be concentrated into about 1.10 (60 ℃) of relative density, adding starch is an amount of, and the back of granulating is divided in the 1# capsule shells of packing into, promptly.
Claims (2)
1. pharmaceutical composition with immunoregulation effect, make with following amount amount part proportion raw material medicine:
Radix Astragali 8-15 part, Radix Ginseng 3-10 part, Bulbus Allii 3-10 part, Radix Glycyrrhizae 2-5 part.
2. pharmaceutical composition according to claim 1 is characterized in that: amount amount part proportioning of described crude drug is:
Radix Astragali 10-12 part, Radix Ginseng 5-8 part, Bulbus Allii 5-8 part, Radix Glycyrrhizae 3-4 part.
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CN2009102255678A CN102085294A (en) | 2009-12-03 | 2009-12-03 | Medicinal composition with immunoregulation effect |
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CN2009102255678A CN102085294A (en) | 2009-12-03 | 2009-12-03 | Medicinal composition with immunoregulation effect |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104984023A (en) * | 2015-06-09 | 2015-10-21 | 王跃进 | Garlic polysaccharide soft capsule |
CN108159178A (en) * | 2018-02-09 | 2018-06-15 | 陕西医大血友病研究院 | A kind of immunological regulation mixture and application |
CN114712474A (en) * | 2022-05-10 | 2022-07-08 | 吉林天新医药科技有限公司 | Traditional Chinese medicine composition for treating lung cancer and preparation method and application thereof |
-
2009
- 2009-12-03 CN CN2009102255678A patent/CN102085294A/en active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104984023A (en) * | 2015-06-09 | 2015-10-21 | 王跃进 | Garlic polysaccharide soft capsule |
CN108159178A (en) * | 2018-02-09 | 2018-06-15 | 陕西医大血友病研究院 | A kind of immunological regulation mixture and application |
CN108159178B (en) * | 2018-02-09 | 2021-03-23 | 陕西医大血友病研究院 | Immunoregulation mixture and application thereof |
CN114712474A (en) * | 2022-05-10 | 2022-07-08 | 吉林天新医药科技有限公司 | Traditional Chinese medicine composition for treating lung cancer and preparation method and application thereof |
CN114712474B (en) * | 2022-05-10 | 2023-09-12 | 吉林天新医药科技有限公司 | Traditional Chinese medicine composition for treating lung cancer and preparation method and application thereof |
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Application publication date: 20110608 |