CN102085235A - Composition having immunity-enhancing effect - Google Patents

Abstract

The invention discloses a composition having immunity-enhancing effect. The composition is prepared from the following raw material medicaments in part by weight: 10 to 20 parts of mushroom, 10 to 15 parts of astragalus, 5 to 8 parts of Indian buead, 2 to 5 parts of largehead atractylodes rhizome and 2 to 5 parts of liquorice. The composition can obviously enhance the immunity by reasonable combination of different medicines and has the characteristics of high safety, low-price and readily available raw materials, low cost and suitability for long-time taking.

Description

A kind of compositions with enhance immunity effect

Technical field

The present invention relates to the pharmaceutical preparations technology field, especially a kind of compositions with enhance immunity effect.

Background technology

The human immune system has three kinds of defencive functions:

1. defense function: the pathogenic microorganism invasion and attack of opposing antibacterial, virus, fungus etc.

2. stabilization function: in time remove dead cell old and feeble in the body,, thereby keep intravital stable with the performance of obstruction free body normal function.

3. immune surveillance function: in time find and eliminate the cell that morphs in the body, prevent the generation of cancer.

Immunologic dysfunction comprises the hyperfunction and immunologic hypofunction of immunologic function.

So-called immunologic hypofunction is exactly that a variety of causes makes immune system normally not bring into play protective effect, in the case, very easily causes infection such as antibacterial, virus, fungus, and various diseases takes place, even causes tumor.

The typical clinical manifestation of immunologic hypofunction is easily various serious infection to take place repeatedly because of losing immune surveillance function, as upper respiratory tract infection, and urinary tract infection, septicemia, meningitis, chickenpox, measles, pulmonary tuberculosis etc.

In addition, opportunistic infection is the characteristic performance of immunologic hypofunction.The toxicity of most of antibacterials, virus, fungus is lower, can not make the normal person ill, but because the patient immune function who has reduction, these hypotoxicity antibacterials, virus, fungus also can infect body, cause disease, thisly be reduced to the infection of condition, be called opportunistic infection by medical circle with immunologic function.The common skin of the patient of opportunistic infection, mucosa, gastrointestinal tract candida albicans infection.Due to illness the people often infects, and has strengthened the consumption of body, so generally have a delicate constitution, performance such as malnutrition, listlessness, fatigue and weak, appetite depression, sleep disorder.Serious immunologic hypofunction person is arranged, behind inoculation attenuation challenge virus or antibacterial vaccine, can cause serious opportunistic infection, even cause that causing gangrenosum acne reacts.

At present, control immunologic hypofunction, the particularly key of Secondary cases immunologic hypofunction is the function that improves immunocyte.The medicine of enhancing immunity commonly used adopts genetic engineering to produce more at present, and the production cost height costs an arm and a leg, unsuitable life-time service.The Lac regis apis that can often take during even expert advice keeps healthy usually, fish zamene, Oleum Bulbus Allii, lecithin, Radix Panacis Quinquefolii etc., all price is high, and for the immunologic hypofunction patient that needs are often taken, its financial burden is also well imagined.

Summary of the invention

Main purpose of the present invention just provides a kind of compositions with enhance immunity effect safe and effective and with low cost.

In order to realize the foregoing invention purpose, the technical solution used in the present invention is as follows:

A kind of compositions with enhance immunity effect, make with following amount amount part proportion raw material medicine:

Lentinus Edodes 10-20 part, Radix Astragali 10-15 part, Poria 5-8 part, Rhizoma Atractylodis Macrocephalae 2-5 part, Radix Glycyrrhizae 2-5 part.

The crude drug proportioning of above-mentioned composition can be preferably:

Lentinus Edodes 15-20 part, Radix Astragali 12-15 part, Poria 5-6 part, Rhizoma Atractylodis Macrocephalae 2-3 part, Radix Glycyrrhizae 2-3 part.

Medicine of the present invention can be according to the conventional preparation method preparation of various peroral dosage form medicines.

In each crude drug of the present composition:

Lentinus Edodes is the sporophore of Agaricales Tricholomataceae Lentinus Lentinus Edodes Lentinus edodes (Berk.) sing.---the inducing agent double stranded RNA of lentinan, blood fat reducing composition---Lentinus Edodes is given birth to very much, Lentinus Edodes adenine and the derivant of adenine, antiviral composition---interferon etc. that contain antineoplastic component.The effect that invigorating the liver and kidney, strengthening the spleen and stomach, replenishing QI and blood, intelligence promoting and the mind tranquilizing, beauty treatment face are arranged.But phlegm-eliminiating and qi-regulating also, stomach reinforcing and in, detoxifcation, antitumor, holder varioliform exanthema.

The Radix Astragali is the root of leguminous herbaceous plant's Radix Astagali, Radix Astragali.Mainly contain flavones ingredient calycosin (calycosin), 3-hydroxyl-9,10-dimethoxy Lignum pterocarpi indici alkane also contains astragaloside I, V, III compositions such as (astragaloside I, V, III).Have effects such as invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Be usually used in that the deficiency of vital energy is weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle are difficultly burst, burst for a long time do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst and chronic nephritis proteinuria, diabetes.

Poria is Polyporaceae fungus Poria Wolfiporia cocos (Schw.) Ryv.﹠amp; The dry sclerotia of Gibn.Contain compositions such as B-pachyman, pachymic acid, lecithin and sterol.Function with promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming; Be used for that edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool are had loose bowels, irritability, palpitation with fear insomnia.Modern pharmacological research confirms that it has effects such as diuresis, antibacterial action, the protective effect to hepatic injury, antitumor action, raise immunity.

The Rhizoma Atractylodis Macrocephalae is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..Contain volatile oil 1.4%, main component is atractylol (Atractylol), atractylone (Atractylon) etc., and contains vitamin A.Rhizome contains volatile oil about 1.4%, contain atractylone (a-tractylone) in the oil, still contain butenolide A, second (butenolide A, B), celery alkane dienone [selina-4 (14), 7 (11)-dien-8-one], β-celery oil alkene (β-Se-linene), Eucalyptus terpene (aromaden-drene); Other contains oxygen Coumarins (oxicoumarines), saccharide and resin etc.Have invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect; Be used for that insufficiency of the spleen lack of appetite, abdominal distention are had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Modern study confirms effects such as the Rhizoma Atractylodis Macrocephalae also has the gastrointestinal motility of adjustment function, antiulcer, protects the liver, enhancing human body immunity function, anti-stress, enhancing hemopoietic function, diuresis, inhibition uterine contraction, antioxidation, slow down aging, blood sugar lowering, anticoagulation, antitumor.

Radix Glycyrrhizae is dicotyledon pulse family Leguminosae Radix Glycyrrhizae Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. G.inflata Bat., or the root and rhizome of Glycyrrhiza glabra L. G.glabra L..Have effects such as invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.But be usually used in the anxious pain of weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, and cushion toxicity and strong.

Compared with prior art, the invention has the beneficial effects as follows: the present composition is reasonably combined by different pharmaceutical, and the enhance immunity effect is obvious, and safety is good; And raw material is cheap and easy to get, and cost is lower, suits to take for a long time.

The specific embodiment

The present invention is described in further detail below in conjunction with the specific embodiment.

Embodiment 1

Present embodiment has the compositions of enhance immunity effect and makes with following amount amount part proportion raw material medicine:

20 parts on Lentinus Edodes, 15 parts of the Radixs Astragali, 5 parts in Poria, 3 parts of the Rhizoma Atractylodis Macrocephalaes, 2 parts in Radix Glycyrrhizae.

Embodiment 2

Present embodiment has the compositions of enhance immunity effect and makes with following amount amount part proportion raw material medicine:

10 parts on Lentinus Edodes, 12 parts of the Radixs Astragali, 6 parts in Poria, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 5 parts in Radix Glycyrrhizae.

Embodiment 3

Present embodiment has the compositions of enhance immunity effect and makes with following amount amount part proportion raw material medicine:

15 parts on Lentinus Edodes, 10 parts of the Radixs Astragali, 8 parts in Poria, 2 parts of the Rhizoma Atractylodis Macrocephalaes, 3 parts in Radix Glycyrrhizae.

The various embodiments described above medicine is all by following method preparation: the crude drug of getting described ratio mixes, and adds 12 times of water boiling and extraction 2 hours, filters filtrate for later use; Filtering residue added 10 times of water boiling and extraction 1.5 hours again, filtered filtrate for later use; Filtering residue added 8 times of water boiling and extraction 1 hour again, filtered; Merge three times filtrate, be concentrated into about 1.10 (60 ℃) of relative density, adding starch is an amount of, and the back of granulating is divided in the 1# capsule shells of packing into, promptly.

Claims (2)

1. compositions with enhance immunity effect, make with following amount amount part proportion raw material medicine:

Lentinus Edodes 10-20 part, Radix Astragali 10-15 part, Poria 5-8 part, Rhizoma Atractylodis Macrocephalae 2-5 part, Radix Glycyrrhizae 2-5 part.

2. compositions according to claim 1 is characterized in that: amount amount part proportioning of described crude drug is:

Lentinus Edodes 15-20 part, Radix Astragali 12-15 part, Poria 5-6 part, Rhizoma Atractylodis Macrocephalae 2-3 part, Radix Glycyrrhizae 2-3 part.