CN101474252A - Chinese medicine granular formulation for treating female postpartum disease - Google Patents
Chinese medicine granular formulation for treating female postpartum disease Download PDFInfo
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- CN101474252A CN101474252A CNA2009100210047A CN200910021004A CN101474252A CN 101474252 A CN101474252 A CN 101474252A CN A2009100210047 A CNA2009100210047 A CN A2009100210047A CN 200910021004 A CN200910021004 A CN 200910021004A CN 101474252 A CN101474252 A CN 101474252A
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Abstract
The invention relates to a Chinese patent drug for treating post labour diseases, in particular to the drug of curing the ceaseless post labour lochia and the lower abdomen crymodynia caused by the qi deficiency and blood stasis and a method for preparing the Chinese patent drug. The Chinese patent drug comprises traditional Chinese medicinal materials, i.e. six milk veteh, angelica, radix salviae miltiorrhizae, radix codonopsitis, motherwort and herba patriniae, has the functions of tonifying qi, nourishing the blood and promoting blood circulation by removing blood stasis and excellent effects of curing and preventing ceaseless post labour lochia, lower abdomen crymodynia and other symptoms caused by qi deficiency and blood stasis, and can obviously lesson the threat of the disease symptoms on female patients.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of female postpartum disease, especially relate to Chinese medicine granules of symptoms such as the postpartum lochiorrhea for the treatment of due to women's blood stasis due to qi deficiency in puerperal, lower abdomen pain and preparation method thereof.
Background technology
Lochia, lower abdomen pain are present women's common diseases in puerperal.The women produces the consumption gas of losing blood, and the unable promotion blood operation of the deficiency of vital energy, so that thrombosis are sluggish and produce stomachache.Deficiency of vital energy insufficiency of blood, puerperal is overstrain impairing the spleen again, so that the debility of CHONG and REN meridians, can not take the photograph blood, and cause lochia.Joining female blood nourishing granule is that employing Chinese medicine is primary raw material, and effective component extracting develops, and has benefiting QI and nourishing blood, the effect of blood circulation promoting and blood stasis dispelling, and Radix Astragali tonifying Qi and lifting yang, benefiting QI for strengthening the superficies in the side, Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving.Two medicines share, and play the effect of benefiting QI and nourishing blood altogether.Radix Codonopsis and Radix Astragali compatibility, Radix Salviae Miltiorrhizae and Radix Angelicae Sinensis compatibility play that the monarch and his subjects want to help, the synergism of the mutual-assistance, have obviously strengthened clinical efficacy.The Herba Leonuri promoting blood flow to regulate menstruation, the Sonchus brachyotus DC. removing blood stasis and expelling pus.Full side's compatibility uses, Qi deficiency blood stasis type puerperal disease patient's the tcm clinical practice symptom and improvement, recovery and the shortening course of disease of tongue pulse condition played a positive role,
The present invention is a kind of Chinese medicine granules, is to adopt the traditional Chinese herbal medicine of China to be prepared from, and it has overcome the big shortcoming of western medicine side effect, the Chinese medicine granules of a kind of tool benefiting QI for activating blood circulation effect that finds out.
Summary of the invention
The object of the invention is to provide a kind of prescription science, preparation and the Chinese medicine granules that is exclusively used in treatment women puerperal disease easy to use, that curative effect is high by excavating motherland's Chinese medicine resource.
The present invention is achieved in that its main formula is the compound Chinese medicinal preparation that the crude drug by following component and weight portion processes:
134～200 parts of 134～200 parts of Radix Salviae Miltiorrhizaes of 134～200 parts of Radix Codonopsis of the Radix Astragali
107～161 parts of 107～161 parts of Sonchus brachyotus DC. of 107～161 parts of Herba Leonuris of Radix Angelicae Sinensis
Its preparation method is:
With above Six-element medical material, decoct with water 1～3 time, each 1～3 hour, collecting decoction, filter, filtrate decompression is concentrated into the clear paste that relative density is 1.10～1.20 (50～70 ℃), adds ethanol and makes and contain alcohol amount and reach 40～80%, leaves standstill 12～48 hours, filter, filtrate recycling ethanol, extractum added 1～3 times of amount of water, 60～100 ℃ of insulations 15～45 minutes, cold preservation 10～14 hours, filter, filtrate is concentrated into the thick paste that relative density is 1.35～1.40 (50～70 ℃), gets thick paste, add stevioside glycosides, dextrin and ethanol, make granule, drying, promptly.
Chinese medicine astragalus (over sixty years of age) is plain to be celebrated with " all medicines of QI invigorating ", is a kind of famous and precious Chinese crude drug, also is a kind of the most frequently used Chinese crude drug." Radix Astragali that records of Chinese pharmacopoeia is the dry root of leguminous plant Radix Astagali or Radix Astragali.Its medicinal history existing more than 2000 year so far, its effective ingredient is flavones ingredient calycosin (calycosin), 3-hydroxyl-9,10-dimethoxy Lignum pterocarpi indici alkane, also contain astragaloside I, V, III (astragaloside I, V, III), but invigorating QI to consolidate the body surface resistance, the diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.When the root that is classified as umbelliferae angelica Angelica sinensis (Oliv.) Diels, contain basic lactone (ligusiilide), n-butene acyl lactone (n-butylidene phthalide), ferulic acid, nicotinic acid, sucrose and several amino acids etc.Can enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Codonopsis is the dry root of campanulaceae plant Radix Codonopsis Codonopsis pilosula (Franch.) Nannf., plain flower Radix Codonopsis Codonopsis pilosula Nannf.var.modesta (Nannf.) L.T.Shen or radix codonpsis tangshen Codonopsis tangshen Oliv..Contain polysaccharide (Polysaccharides), phenols (Phenols) etc.But invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.Radix Salviae Miltiorrhizae is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bge., the root master contains diterpene quinones pigment, TANSHINONES (tanshinone) I, II A, II B, cryptotanshinone (cryptotanshinone), iso tanshinone (isotanshinones) I, II, different cryptotanshinone (lsocryptotanshinone), miltirone (miltirone), Methyl tanshinoate (methyl tanshinonate), hydroxyl Tanshinone I I A (hydroxytanshinone) etc.But stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for menoxenia, the amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.Herba Leonuri is the young stem and leaf of labiate Herba Leonuri LeonurusheterophyllusSweet., contains protein (Protein), carbohydrate multiple nutritional components such as (Carbohydrate).Have invigorate blood circulation, the effect of the method stasis of blood, regulating menstruation, the water that disappears.Control water, hematuria under menoxenia, the edema, rush down blood, dysentery, haemorrhoids.The Sonchus brachyotus DC. hardship is trembled with fear, and the function of heat-clearing and toxic substances removing, detumescence and apocenosis, blood stasis dispelling is arranged.Be used for appendicitis, enteritis, dysentery, skin ulcer furuncle carbuncle, hemorrhoid, postnatal blood stasis stomachache.
The present invention's medication of suiting the medicine to the illness is executed and is controlled, and prescription is scientific and reasonable, and crude drug source extensively is easy to get, and cost is low, safe without toxic side effect, and drug effect is fast, and is easy to use, is the preferred medication of symptoms such as postpartum lochiorrhea due to clinical treatment women QI and blood in the puerperal blood stasis, lower abdomen pain.
The specific embodiment 1: the Radix Astragali 134 grams, Radix Codonopsis 134 grams, Radix Salviae Miltiorrhizae 134 grams, Radix Angelicae Sinensis 107 grams, Herba Leonuri 107 grams, Sonchus brachyotus DC. 107 grams, with above Six-element medical material, decoct with water each 1 hour 1 time, collecting decoction filters, and filtrate decompression is concentrated into the clear paste that relative density is 1.10～1.20 (50 ℃), add ethanol and make and contain alcohol amount and reach 40%, left standstill 12 hours, filter, filtrate recycling ethanol, extractum added 1 times of amount of water, 60 ℃ of insulations 15 minutes, cold preservation 10 hours, filter, filtrate is concentrated into the thick paste that relative density is 1.35～1.40 (50 ℃), gets thick paste, add stevioside glycosides 2.14 grams, dextrin 176 gram and ethanol, make granule, drying, promptly.
The embodiment of the invention 2: the Radix Astragali 167 grams, Radix Codonopsis 167 grams, Radix Salviae Miltiorrhizae 167 grams, Radix Angelicae Sinensis 134 grams, Herba Leonuri 134 grams, Sonchus brachyotus DC. 134 grams, with above Six-element medical material, decoct with water each 2 hours 2 times, collecting decoction filters, and filtrate decompression is concentrated into the clear paste that relative density is 1.10～1.20 (60 ℃), add ethanol and make and contain alcohol amount and reach 65%, left standstill 24 hours, filter, filtrate recycling ethanol, extractum added 2 times of amounts of water, 80 ℃ of insulations 30 minutes, cold preservation 12 hours, filter, filtrate is concentrated into the thick paste that relative density is 1.35～1.40 (60 ℃), gets thick paste, add stevioside glycosides 2.68 grams, dextrin 220 gram and ethanol, make granule, drying, promptly.
The embodiment of the invention 3: the Radix Astragali 200 grams, Radix Codonopsis 200 grams, Radix Salviae Miltiorrhizae 200 grams, Radix Angelicae Sinensis 161 grams, Herba Leonuri 161 grams, Sonchus brachyotus DC. 161 grams, with above Six-element medical material, decoct with water each 3 hours 3 times, collecting decoction filters, and filtrate decompression is concentrated into the clear paste that relative density is 1.10～1.20 (70 ℃), add ethanol and make and contain alcohol amount and reach 80%, left standstill 48 hours, filter, filtrate recycling ethanol, extractum added 3 times of amounts of water, 100 ℃ of insulations 45 minutes, cold preservation 14 hours, filter, filtrate is concentrated into the thick paste that relative density is 1.35～1.40 (70 ℃), gets thick paste, add stevioside glycosides 3.22 grams, dextrin 264 gram and ethanol, make granule, drying, promptly.
Usage and dosage: boiled water is taken after mixing it with water, a 8g, 3 times on the one.
Claims (6)
1, a kind of Chinese medicine granules for the treatment of female postpartum disease, it is characterized in that: it is made by Six-element Chinese herbal medicine such as the Radixs Astragali, and each Chinese herbal medicine proportioning by weight of distinguishing the flavor of is respectively:
134～200 parts of 134～200 parts of Radix Salviae Miltiorrhizaes of 134～200 parts of Radix Codonopsis of the Radix Astragali
107～161 parts of 107～161 parts of Sonchus brachyotus DC. of 107～161 parts of Herba Leonuris of Radix Angelicae Sinensis
2, a kind of Chinese medicine granules for the treatment of female postpartum disease, it is characterized in that: it is made by Six-element Chinese herbal medicine such as the Radixs Astragali, and each Chinese herbal medicine proportioning by weight of distinguishing the flavor of is respectively:
167 parts of 167 parts of Radix Salviae Miltiorrhizaes of 167 parts of Radix Codonopsis of the Radix Astragali
134 parts of 134 parts of Sonchus brachyotus DC. of 134 parts of Herba Leonuris of Radix Angelicae Sinensis
3, according to the compound Chinese medicinal preparation of claim 1 treatment female postpartum disease, it is characterized in that: main formula can also add following component and weight portion:
176～264 parts in 2.14～3.22 parts of dextrin of stevioside
4, according to the compound Chinese medicinal preparation of claim 2 treatment female postpartum disease, it is characterized in that: main formula can also add following component and weight portion:
220 parts in 2.68 parts of dextrin of stevioside
5, as claim 1,3 described a kind of preparation of drug combination methods for the treatment of female postpartum disease, its preparation technology is: the Radix Astragali, Radix Codonopsis, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Herba Leonuri, Sonchus brachyotus DC., with above Six-element medical material, decoct with water 1-3 time, each 1-3 hour, collecting decoction, filter, filtrate decompression is concentrated into the clear paste that relative density is 1.10～1.20 (50 ℃-70 ℃), adds ethanol and makes and contain alcohol amount and reach 40-80%, leaves standstill 12-48 hour, filter, filtrate recycling ethanol, extractum added 1～3 times of amount of water, 60～100 ℃ of insulations 15-45 minute, cold preservation 10-14 hour, filter, filtrate is concentrated into the thick paste that relative density is 1.35～1.40 (50～70 ℃), gets thick paste, add the stevioside glycosides, dextrin and ethanol, make granule, drying, promptly.
6, as claim 2,4 described a kind of preparation of drug combination methods for the treatment of female postpartum disease, its preparation technology is: the Radix Astragali, Radix Codonopsis, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Herba Leonuri, Sonchus brachyotus DC., with above Six-element medical material, decoct with water 2 times, each 2 hours, collecting decoction, filter, filtrate decompression is concentrated into the clear paste that relative density is 1.10～1.20 (60 ℃), adds ethanol and makes and contain alcohol amount and reach 65%, leaves standstill 24 hours, filter, filtrate recycling ethanol, extractum added 2 times of amounts of water, 80 ℃ of insulations 30 minutes, cold preservation 12 hours, filter, filtrate is concentrated into the thick paste that relative density is 1.35～1.40 (60 ℃), gets thick paste, add the stevioside glycosides, dextrin and ethanol, make granule, drying, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CNA2009100210047A CN101474252A (en) | 2009-01-21 | 2009-01-21 | Chinese medicine granular formulation for treating female postpartum disease |
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| CNA2009100210047A CN101474252A (en) | 2009-01-21 | 2009-01-21 | Chinese medicine granular formulation for treating female postpartum disease |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102657699A (en) * | 2012-06-01 | 2012-09-12 | 西安仁仁药业有限公司 | Cane sugar-containing and sugar-free Shenkun blood nourishing granules with longer period of validity |
| CN103285279A (en) * | 2013-06-22 | 2013-09-11 | 李伟丽 | Traditional Chinese medicine composition for promoting gravid postpartum recovery, and applications thereof |
-
2009
- 2009-01-21 CN CNA2009100210047A patent/CN101474252A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102657699A (en) * | 2012-06-01 | 2012-09-12 | 西安仁仁药业有限公司 | Cane sugar-containing and sugar-free Shenkun blood nourishing granules with longer period of validity |
| CN102657699B (en) * | 2012-06-01 | 2014-04-30 | 西安仁仁药业有限公司 | Cane sugar-containing and sugar-free Shenkun blood nourishing granules with longer period of validity |
| CN103285279A (en) * | 2013-06-22 | 2013-09-11 | 李伟丽 | Traditional Chinese medicine composition for promoting gravid postpartum recovery, and applications thereof |
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Open date: 20090708 |