CN103961521A - Traditional Chinese medicine composition for treating aplastic anemia and preparation method - Google Patents

Traditional Chinese medicine composition for treating aplastic anemia and preparation method Download PDF

Info

Publication number
CN103961521A
CN103961521A CN201410005401.6A CN201410005401A CN103961521A CN 103961521 A CN103961521 A CN 103961521A CN 201410005401 A CN201410005401 A CN 201410005401A CN 103961521 A CN103961521 A CN 103961521A
Authority
CN
China
Prior art keywords
parts
radix
blood
fructus
herba
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410005401.6A
Other languages
Chinese (zh)
Inventor
魏红卫
董建中
魏思怡
闫杰青
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201410005401.6A priority Critical patent/CN103961521A/en
Publication of CN103961521A publication Critical patent/CN103961521A/en
Pending legal-status Critical Current

Links

Abstract

The invention discloses traditional Chinese medicine composition for treating aplastic anemia and a preparation method, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared to form a formula according to the principle of the monarch, the minister, the assistant andthe guide; in the formula, astragalus, dried rehmannia roots, cooked rehmannia roots, glossy privet fruits and the like serve as the monarch; barbarywolfberry fruits, herbaepimedii, moutan bark, Chinese wolfberry root-bark, deerhorn glue and the like serve as the minister; herbaecliptae, ass hide glue, red paeony roots and the like serve as the assistant; and red dates, liquorice and the like serve as the guide; all the medicines are combined to achieve effects of curing livers, spleens and kidneys simultaneously and recovering functions of hematopoietic stem cells. The composition is mainly used for treating the aplastic anemia, can increase marrow hematopoietic cells, can remove hectic fever due to yin deficiency, can repair bones and add marrow, has an obvious promoting effect on generation of granulocytic erythrocytes and erythroid progenitor cells, can accelerate generation, differentiation and maturity of the hematopoietic cells, can improve the immune function, reduce damage to immune leukocytes, stimulate and activate the hematopoietic function, enables erythrocytes to generate blood vigorously, can promote generation of the erythrocytes and the leukocytes, can increase the number of blood platelets, can enhance functions of the blood platelets and the like.

Description

One is used for the treatment of the hemopathic Chinese medicine composition of aplastic and preparation method
Technical field
The present invention is specifically related to one and is used for the treatment of the hemopathic Chinese medicine composition of aplastic, and the preparation method of this Chinese medicine composition, belongs to Chinese medicine technical field.
Background technology
Aplastic anemia is a kind of hematopathy, popular title is just aplastic anemia, be one group and cause marrow hematopoiesis function failure by certain or complex factors, the disease of peripheral blood pancytopenia, the main cause of disease is the blood disorder that versatile stem cell generation pathological changes causes, and is also the most common illness of inpatient with haematological diseases death.
The pathogenic factor of aplastic anemia comprises the many factors such as physics, chemistry, biology.Quite a few case, fails to find clear and definite reason, is referred to as former or idiopathic aplastic anemia.What those had that reason can look into is called Secondary cases aplastic anemia.Physical factor: there is ionizing radiation (x light, radionuclide, atomic bomb etc.) the common cytopenia of ionizing radiation, so that the inhibition of irreversible bone marrow hematogenesis, there is aplastic anemia.Chemical factor: have medicine and chemical substance (antipyretic analgesic, non-steroidal anti-inflammatory agent, antibiotic, the calmness of sleeping peacefully, antimalarial, pesticide, antitumor drug etc.), chloromycetin can directly cause aplastic anemia, bans use of.The relation of benzene and aplastic anemia is also very close, and the increment maturation of benzene interference cell, can cause marrow failure, forms aplastic anemia, also can cause leukemia.Some medicines suppress hemopoietic and in its structure, to contain benzene relevant.Biological factor: (hepatitis B virus, Measles virus, HIV-1, piconavirus B19 etc., can be due to direct cell toxicant, or causes host immune cytotoxicity, makes myelosis suppressed for virus.Gestation also has relation with aplastic anemia, may be pregnancy period endocrine alteration, causes aplastic anemia.
Normal marrow hemopoietic be hematopoietic stem cell in suitable hematopoieticmicroenviron-ment hypertrophy, differentiation, ripe for each be hemocyte, and be released into peripheral blood.Aplastic anemia is because the factors such as chemistry, physics and biology cause hematopoietic stem cell defect, hematopoieticmicroenviron-ment damage, immunologic mechanism imbalance, cause marrow hematopoiesis function failure, the red pulp fatization of bone marrow, cause pancytopenia, reticulocyte is also few, myelosis is low, clinically taking anemia, hemorrhage and be easy to infect as feature.According to this sick onset emergency, state of an illness weight, bone marrow injury degree with lapse to, be divided into two kinds of acute aplastic anemia (abbreviation acute aplastic anemia), chronic aplastic anemias (abbreviation chronic aplastic anemia).
Aplastic anemia patient shows effect and is mostly acute, and symptom is more serious, and this part patient's early stage outstanding symptom is infection and hemorrhage.Often have obviously weakly, dizziness, cardiopalmus, breathe hard, and be the aggravation of carrying out property.Bleeding tendency weight, almost all has skin purpura or ecchymosis, oral mucosal hematoma, gingival hemorrhage, epistaxis, digestive tract hemorrhage as having blood in stool, hematemesis, hematuria, woman in menstrual period amount be many, also has retinal hemorrhage to cause visual disorder, intracranial hemorrhage threat to life.The easy concurrent infection of patient, therefore heating is very common, the high heat that continues, occurs repeatedly.Superficial lymph knot, liver spleen are generally without enlargement.Acute aplastic anemia is pluripotential hemopoietic stem cell pathological changes.This class case is dangerously ill, the course of disease is very brief.
Slowly, main performance is usually lassitude, tired rear tachypnea, cardiopalmus, dizziness, pale complexion in the state of an illness outbreak of chronic aplastic anemia.If any hemorrhage also slighter, visceral hemorrhage is more rare.Infect, heating generally slighter, occur more late, more easy to control after treatment.Liver, all not enlargements of splenic lymph nodes, chronic aplastic anemia is that myeloid stem cell is impaired.Have spleen silght enlargement but late case is even, the course of disease is longer, and some patients were changes acute into.
Aplastic anemia belongs to the traditional Chinese medical science " asthenia, exhaustion of blood, mass formed by blood stasis " category.The traditional Chinese medical science is thought the not outer congenital defect of its reason of aplastic anemia, bothers excessively, and wind god is weak, kidney channel virtual loss, and the evil poison of diseases caused by exogenous pathogenic factor waits and injures QI and blood, internal organs, especially has influence on kidney,spleen,liver and bone marrow.For the generation of blood, all there is relation with the five internal organs, but taking spleen kidney as main." middle Jiao extracting juice of being bullied, changes and red, is meaning blood "." the middle burnt person of being bullied, separating the essence from the waste, steams body fluid, changes that it is precise and tiny, on note in the lung pulse, being and be blood " point out the i.e. effect of middle Jiao in hemopoietic of taste, therefore there be " blood person essence-QI from water and grain is also ".The important substance of hemopoietic is mainly absorbed from taste, must be through the effect ability hemopoietic of kidney, the kidney being the origin of congenital constitution, main store essential substances, raw marrow, sturdy skeleton, regular circulation of QI-blood, the source of blood is kidney, and essence and blood sharing the same origin, the spleen being the foundation of acquired constitution, source of generating QI and blood, liver storing blood, three is dirty impaired and cause all diseases of asthenia blood deficiency.Natural endowment deficiency, bothers excessively, the evil poison of knot or diseases caused by exogenous pathogenic factor in blood stasis, or interior traumatic condition will, or obstinate disease, all cause QI and blood not smooth, congestion retardance and fresh blood is raw, or the disease of asthenia blood deficiency, eating and drinking without temperance, exopathogen invasion, in poison of drug enters, the source kidney essense of bone marrow hematogenesis is short, the disease of causing asthenia, blood deficiency.
Aplastic anemia is hemopoietic system exhaustion, and the red bone marrow originally with hemopoietic function is progressively converted into the yellow bone marrow that does not possess hemopoietic, and after normal hemocyte death, health can not supplement new cell in time fully, so there is the symptom of pancytopenia.Only have the hemostasis of realization, blood coagulation, enrich blood, hemopoietic, activated bone marrow hematopoietic stem cell, could effectively cure aplastic anemia.And the good recipe of not curing at present.
Summary of the invention
The object of this invention is to provide one and be used for the treatment of the hemopathic Chinese medicine composition of aplastic.
Meanwhile, the present invention also provides a kind of preparation method that is used for the treatment of the hemopathic Chinese medicine composition of aplastic.
In order to realize above object, the technical solution adopted in the present invention is:
One is used for the treatment of the hemopathic Chinese medicine composition of aplastic, is made up of the crude drug of following parts by weight: 15～20 parts of Fructus Ligustri Lucidi, 15～25 parts of Herba Ecliptaes, 15～25 parts of Radix Polygoni Multiflori Preparata, 15～20 parts of Fructus Lycii, 10～20 parts, Radix Rehmanniae Preparata, 20～30 parts, the Radix Rehmanniae, 15～25 parts of Carapax et Plastrum Testudiniss, 15～25 parts of the Radixs Astragali, 10～20 parts of Fructus Corni, 10～15 parts of Herba Epimedii, 10～15 parts of Cortex Moutans, 10～15 parts of Cortex Lycii, 15～25 parts of Carapax Trionycis (processed)s, 15～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Semen Cuscutae, 9～12 parts of Radix Panacis Quinquefoliis, 9～15 parts, Colla Corii Asini, 20～25 parts of Herba Agrimoniaes, 15～25 parts of Colla cornus cervis, 10～25 parts of Radix Codonopsis, 9～15 parts of the Rhizoma Atractylodis Macrocephalaes, 10～15 parts of Radix Paeoniae Rubra, 15～25 parts of Radix Angelicae Sinensis, 15～25 parts of Fructus Mori, 9～15 parts of the Rhizoma Anemarrhenaes, 15～25 parts of Herba Hedyotidis Diffusaes, 9～15 parts of Fructus Psoraleaes, 9～12 parts of Radix Scutellariaes, 6～12 parts of Rhizoma Coptidis, 15～20 parts of Folium Isatidiss, 15～25 parts of Squama Maniss, 10～15 parts of Radix Scrophulariaes, 6～12 parts of Cornu Bubalis, 20～30 parts of Caulis Spatholobis, 10～15 parts, Poria, 3～6 parts of Radix Aconiti Lateralis Preparatas, 15～25 parts of Fructus Jujubaes, 6～12 parts, Radix Glycyrrhizae, 50～100 parts, Semen sojae atricolor face, 50～100 parts of Carnis Sus domesticas, 15～25 parts, brown sugar, 9～15 parts of Nodus Nelumbinis Rhizomatis.
Preferably, be used for the treatment of the hemopathic Chinese medicine composition of aplastic, crude drug by following parts by weight forms: 15 parts of Fructus Ligustri Lucidi, 25 parts of Herba Ecliptaes, 15 parts of Radix Polygoni Multiflori Preparata, 15 parts of Fructus Lycii, 20 parts, Radix Rehmanniae Preparata, 25 parts, the Radix Rehmanniae, 25 parts of Carapax et Plastrum Testudiniss, 20 parts of the Radixs Astragali, 15 parts of Fructus Corni, 15 parts of Herba Epimedii, 12 parts of Cortex Moutans, 15 parts of Cortex Lycii, 20 parts of Carapax Trionycis (processed)s, 15 parts of Radix Salviae Miltiorrhizaes, 20 parts of Semen Cuscutae, 10 parts of Radix Panacis Quinquefoliis, 10 parts, Colla Corii Asini, 25 parts of Herba Agrimoniaes, 20 parts of Colla cornus cervis, 10 parts of Radix Codonopsis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Radix Paeoniae Rubra, 20 parts of Radix Angelicae Sinensis, 20 parts of Fructus Mori, 10 parts of the Rhizoma Anemarrhenaes, 25 parts of Herba Hedyotidis Diffusaes, 15 parts of Fructus Psoraleaes, 10 parts of Radix Scutellariaes, 6 parts of Rhizoma Coptidis, 20 parts of Folium Isatidiss, 20 parts of Squama Maniss, 10 parts of Radix Scrophulariaes, 9 parts of Cornu Bubalis, 25 parts of Caulis Spatholobis, 15 parts, Poria, 6 parts of Radix Aconiti Lateralis Preparatas, 20 parts of Fructus Jujubaes, 9 parts, Radix Glycyrrhizae, 50 parts, Semen sojae atricolor face, 50 parts of Carnis Sus domesticas, 15 parts, brown sugar, 12 parts of Nodus Nelumbinis Rhizomatis.
Each crude drug effect is summarized as follows:
Fructus Ligustri Lucidi: be the fruit of Oleaceae Ligustrum plant Fructus Ligustri Lucidi; Contain triterpenes as oleanolic acid, acetyloleanolic acid, ursolic acid, acetyl ursolic acid, phenolic glycoside class is as p-hydroxyphenylethanol, foreign syringin etc., iridoid glycosides is as nuzhenide, oleuropein, different nuzhenide etc., also contain flavonoid as raceme eriodictyol, Quercetin etc., and fatty acid is as Palmic acid, oleic acid etc., phospholipid is as LYSO-PHOSPHATIDYLCHOLINE LYSOPC, PHOSPHATIDYL ETHANOLAMINE etc., and volatile oil is as various active compositions such as thioacetones; Nature and flavor sweet, bitter, cold, returns liver, kidney channel, energy liver and kidney tonifying, clearind deficient heat, improving eyesight; Cure mainly Light-headedness, soreness of the waist and knees, tinnitus, early whitening of beard and hair, osteopyrexia and fever etc.; Modern pharmacology proves that Fructus Ligustri Lucidi has antiinflammatory, blood sugar lowering, protects the liver, antimutagenesis etc.
Herba Ecliptae (Herba Tropaeoli): be the herb of Tropaeolaceae nasturtium nasturtium; Seed is containing nasturtium glycosides, benzyl isothiocyanate etc., and quintessence oil is containing benzyl thiocyanate, and stem and leaf is containing isoquercitrin, Quercetin-3-tri-glucose glycosides, chlorogenic acid; Flower is containing Kaempferol Glucoside, and containing multiple carotene, phylloxanthin, zeaxanthine, alpha-carotene, beta-carotene, herb is containing lignin, nasturtium thioglycoside isoreactivity composition; Nature and flavor are pungent, sour, cool; Energy heat-clearing and toxic substances removing, cooling blood for hemostasis; Cure mainly conjunctival congestion and swelling pain, furuncle, haematemesis, spitting of blood; Modern pharmacology proves that Herba Tropaeoli has the effects such as antibacterial, short cardiovascular diastole.
Radix Polygoni Multiflori Preparata: be the Preparation process product of the tuber of Polygonaceae arsesmart Radix Polygoni Multiflori; Contain anthraquinone analog compound as various active compositions such as emodin, chrysophanol, chrysophanic acid anthrone, Radix Polygoni Multiflori the third element, piceids; Nature and flavor hardship, sweet, puckery, tepor, returns liver, the heart, kidney channel; Can nourishing the blood and yin, loosening bowel to relieve constipation, dispel the wind, detoxify; Cure mainly Light-headedness, cardiopalmus, insomnia, soreness of the waist and knees, early whitening of beard and hair, tinnitus, dryness of the intestine constipation, chronic malaria body void, rubella pruritus, carbuncle sore, scrofula etc.; Modern pharmacology proves that Radix Polygoni Multiflori has blood fat reducing, atherosclerosis, enhancing immunity, slow down aging, anti-genetic damage, antiinflammatory, analgesic activity etc.
Fructus Lycii: for Fructus Lycii is the fruit of Solanaceae Lycium plant lycium barbarum; Contain the various active compositions such as Allylamines, polysaccharide, cerebroside, ursolic acid, alkaloid, P-coumaric acid, daucosterol, carotene, atropine, hyoscyamine, Semen Maydis xanthin, physalin, kryptoxanthin, vitamin C; Nature and flavor are sweet, flat, return liver, kidney, lung meridian; Energy nourishing the liver, nourishing kidney, lung moistening; Cure mainly caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, cough due to consumptive disease etc.; Modern pharmacology proves that Fructus Lycii has the effects such as slow down aging, anti-fatty liver, adjusting blood fat and blood glucose, promotion hemopoietic function, can also regulate body's immunity, effectively suppresses tumor growth and cell mutation etc.
Radix Rehmanniae Preparata: for the Radix Rehmanniae is concocted and formed through processing; Nature and flavor are sweet, tepor, return liver, kidney channel; Can enrich blood yin nourishing, life essence-filling, marrow-benefitting; Cure mainly all cards of blood deficiency, sweet Wen Zhirun, nourishing YIN benefit essence, with hemopoietic, is the key medicine of the tonify deficiency that nourishes blood.
The Radix Rehmanniae (Radix Rehmanniae, Radix Rehmanniae): be the tuber of Scrophulariaceae Radix Rehmanniae platymiscium Radix Rehmanniae; Contain iridoid and glycoside thereof as Herba Leonuri glycosides, aucubin, catalpol, Martynoside. A, B, C, D etc., violet ketoside is as Radix Rehmanniae violet glycosides A, B, C etc., monoterpene glycosides glycosides as bitter in Radix Rehmanniae, phenethanol glucosides is as digitophyllin C etc., phenylpropanol glucosides, as echinacosid etc., also contains JNGZ-B 1-b, fatty acid are as plurality of active ingredients such as cinnamic acid, lauric acid, myristic acids; Radix Rehmanniae nature and flavor are sweet, bitter, be slightly cold, GUIXIN, liver, kidney channel; Energy clearing away heat from blood, tonifying YIN blood, promoting blood circulation; Cure mainly epidemic febrile disease heating, jaundice, haematemesis, epistaxis, metrorrhagia, hematuria due to heat in blood, has blood in stool, quench one's thirst, and hectic fever due to YIN-deficiency consumptive fever, amenorrhea, puerperal abdonimal pain, numbness flaccidity, traumatic injury etc.; Modern pharmacology proves that Radix Rehmanniae has the effects such as tumor suppression, antiinflammatory, antifungal, blood sugar lowering, protection gastric mucosa.
Carapax et Plastrum Testudinis: be the carapace of Testudinidae Chinemys animal Testudinis; Carapax Et Plastrum Testudinis (sternite) contains 18 seed amino acids such as cholesterol, sterol-4-alkene-3-ketone, dodecenoic acid cholesterol ester, aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, cystine, methionine, another containing more than 10 kind of inorganic elementss such as chromium, manganese, copper, zinc, phosphorus, magnesium, and contain the oxygenatedchemicalss such as calcium oxide, magnesium oxide, phosphorus pentoxide, silicon dioxide, and ossein, keratin isoreactivity composition; Nature and flavor are salty, sweet, are slightly cold, and return liver, kidney, heart channel; Energy nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone, heart tonifying and tranquilizing, consolidating channel for hemostasis; Cure mainly deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, have a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, wriggling of the limbs, fastening flaccidity are weak, palpitation with fear insomnia, forgetful etc.; Modern pharmacology proves that Carapax et Plastrum Testudinis has the effect of slow down aging, has regulating action to thyroid function, immunologic function, adrenal function etc.
The Radix Astragali: be the root of pulse family Astragalus Radix Astagali and Radix Astragali; Contain saponin component as astragaloside, isoflavones components is as calycosin, and fatty acid is as Palmic acid and linoleic acid, and polysaccharide is as astragalus polysaccharides, heteropolysaccharide etc., and nearly 20 various trace elements; Radix Astragali nature and flavor are sweet, and temperature is returned lung, spleen channel; Energy benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening; Cure mainly the disease of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts and do not hold back for a long time; Modern pharmacology proves that the Radix Astragali can affect organism metabolism and has antioxidation, can also antithrombotic, antiviral, arthritis, anticancer, anti-inflammatory and antalgic, and protection cardio-cerebrovascular and promote hemopoietic function.
Fructus Corni: be the sarcocarp of Cornaceae Macrocarpium plant Fructus Corni, contain tannin composition as Fructus Corni tannin 1-3, cornusiin A-G, clove tree tannin, Herba Diclipterae Chinensis tannin D, gallic acid etc., also contain polyphenol glycoside compound as 7-O-Galla Turcica (Galla Helepensis) acyl-D-sedoheptulose, glucosides composition splits glycosides as Fructus Corni, morroniside, 7-O-methyl morroniside, loganin etc., separately contain cis-oxolane-2, 5-dicarboxylic acids dimethyl esters and threonine, valine, leucine, isoleucine, phenylalanine, aminoacid in histidine etc. 14, and polysaccharide, vitamins, anthocyanin, pentacyclic triterpene and esters isoreactivity composition thereof, nature and flavor acid, tepor, return liver, kidney channel, energy liver and kidney tonifying, convergence are admittedly de-, cure mainly have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, incessant sweating due to debility etc., modern pharmacology proves that Fructus Corni has the effects such as antiinflammatory, arrhythmia, anticoagulant, and immune system, hemorrhagic shock, blood glucose, cardiac function and hemodynamics etc. are had to regulating action.
Herba Epimedii: be stem, the leaf of Radix Berberidis Amurensis gram barrenwort Herba Epimedii, arrow leaf Herba Epimedii, Epimedium wushanense, Herba Epimedii, pubescence Herba Epimedii etc.; Its aerial parts contains flavonoid as epimedium flavone glycosides, epimedium flavone time glycosides I, and inorganic elements is as the various active such as potassium, calcium composition; Nature and flavor acrid, sweet, warm, return kidney, Liver Channel; Energy kidney invigorating and YANG supporting, strengthening the tendons and bones, expelling wind and removing dampness; Cure mainly the cough with asthma of suffering from a deficiency of the kidney, soreness of the waist and knees, rheumatic arthralgia etc.; Modern pharmacology proves that Herba Epimedii has slow down aging, regulates immunologic function, prevents and treats osteoporosis, promotes union of fracture, antitumor action etc.
Cortex Moutan: be the root bark of Paeoniaceae Paeonia plant Paeonia suffruticosa; Contain iridoid glycoside as peoniflorin, oxypaeoniflorin, paeonol, the new phenol of Paeonia suffruticosa etc., also contain the plurality of active ingredients such as gallic acid; Nature and flavor hardship, pungent, be slightly cold, GUIXIN, liver, kidney channel; Energy clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; Cure mainly the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, hot Fu Yin of calentura later stage divides heating, osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus, falls and flutter the pain of injury, rheumatism pyretic arthralgia etc.; Modern pharmacology proves that Cortex Moutan has the effect such as antiinflammatory, blood sugar lowering, and cental system, cardiovascular system, blood system and immunologic function are produced to impact in various degree.
Cortex Lycii: be the root bark of Solanaceae Lycium plant Fructus Lycii, lycium barbarum; Containing alkaloid can amine A etc. as betanin, hardship, and again containing Fructus Lycii ring octapeptide A and B, organic acid is as (S)-9-hydroxyl-10E, 12Z-octadecadienoic acid etc., and lyciumamide, linolenic acid, melissic acid, cinnamic acid, cryptojaponol isoreactivity composition; Nature and flavor are sweet, cold, return lung, kidney channel; Energy clearind deficient heat, purte the white, removing heat from blood; Cure mainly hectic fever due to deficiency of YIN, hectic fever due to YIN-deficiency night sweat, infantile malnutrition heating, dyspnea and cough due to lung-heat, haematemesis, epistaxis, quench one's thirst can; Modern pharmacology provably Cortex Lycii has the effects such as antipyretic, blood pressure lowering, blood sugar lowering.
Carapax Trionycis (processed): for Trionychidae Trionyx sinensis Wiegmann belongs to the Preparation process product of the carapace of animal Trionyx sinensis (Wiegmann) and Trionyxs teindachneri Siebenrock．; Carapace contains ossein, calcium carbonate, calcium phosphate, Toads, and contains 17 seed amino acids such as aspartic acid, threonine, glutamic acid, glycine, alanine, and more than the 10 kind of inorganic elements such as calcium, sodium, potassium, manganese; Nature and flavor are salty, be slightly cold, and return liver, kidney channel; Energy nourishing YIN and clearing away heat, suppressing hyper-yang to eliminate wind, hard masses softening and resolving; Cure mainly fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, consumption of YIN caused by febrile disease, stirring-up of pathogenic wind in the interior resulting from deficiency, pediatric epilepsy scared, Nve, mass in the abdomen of a specified duration etc.; Modern pharmacology prove Carapax Trionycis have enrich blood, the effect such as antitumor, mutation, anti-hepatic fibrosis.
Radix Salviae Miltiorrhizae: be the root of Labiatae salvia Radix Salviae Miltiorrhizae; Contain quinones as TANSHINONES, Radix Salviae Miltiorrhizae ketolide, water-soluble phenolic compounds is as salvianolic acid, protocatechuic acid, and fatty acid, as linolenic acid, linoleic acid, also contains the various active such as baicalin, daucosterol composition; Nature and flavor hardship, is slightly cold, GUIXIN, pericardium, Liver Channel; Energy blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, removing heat from blood eliminating carbuncle; Cure mainly that menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swell and ache, traumatic injury, thermal man's nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.; Modern pharmacology proves that Radix Salviae Miltiorrhizae exerts an influence to cardio-cerebrovascular, respiratory system, blood fat and atherosclerosis, liver, tumor and immunologic function etc., also has the effects such as antiinflammatory, antiallergic, anti-gastric-ulcer.
Semen Cuscutae: be the seed of Convolvulaceae Hellweed Semen Cuscutae; Seed contains flavonoid as Quercetin, Herba Astragali Melilotoidis (Herba Astragali Sinici) glycosides, hyperin etc.; South Semen Cuscutae fruit contains a large amount of alkaloids, seed contains new Semen Sesami ester element, Palmic acid, stearic acid, daucosterol and sterols as cupreol, stigmasterol, 5-avenasterol etc., flavonoid, as kaempferol, Herba Astragali Melilotoidis (Herba Astragali Sinici) glycosides, Quercetin, lacceroic acid etc., also contains the various active compositions such as southern Semen Cuscutae glycosides A, thymidylic acid, caffeic acid, p-hydroxycinnamic acid; Nature and flavor are pungent, sweet, flat, return liver,kidney,spleen warp; Can the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, the stopping leak that begins admittedly; Cure mainly soreness of waist and knee joint, blurred vision tinnitus, have loose bowels etc.; Modern pharmacology proves that the Cortex Eucommiae has and strengthens the effect such as immune, anticancer.
Radix Panacis Quinquefolii (Radix Panacis Quinquefolii): be the root of araliaceae ginseng plant's Radix Panacis Quinquefolii, Radix Panacis Quinquefolii master is containing triterpene saponin, taking neat honest fruit alkane as aglycon by pregnant saponin-Ro, taking 20 (S) protopanoxadiol as the pregnant saponin-Rb of having of aglycon 1and-RAo, Radix Panacis Quinquefolii saponin-R 1, gypenoside VII, X and XI etc., also contain volatile oil as β-farnesene, capryl alcohol, caproic acid, hendecane, 10-Pinen-3-ol, sad etc., polyacetylene constituents is as sickleleaf celery alcohol, panaxytiol, panaxydol etc., in oils and fats, fatty acid is as caproic acid, enanthic acid, sad, Palmic acid, oleic acid, linolenic acid etc., phospholipid is as diphosphatidylglycerol, phosphatidylcholine, LYSO-PHOSPHATIDYLCHOLINE LYSOPC etc., similar as panose, sorbose, fructose, glucose, sucrose, maltose etc., aminoacid is as aspartic acid, threonine, serine etc., also contain steroidal compounds as daucosterol, stigmastenol etc., separately contain ferrum, aluminum, calcium, barium, the inorganic elementss such as copper and vitamin A, B 1, B 2isoreactivity composition.
Colla Corii Asini (Colla Corii Asini): the skin of unhairing that belongs to animal donkey for equine donkey is through boiling the glue forming; Colla Corii Asini is a class glutin, hydrolysis can produce several amino acids, mainly contain glycine, proline, glutamic acid, alanine, arginine, aspartic acid, lysine, phenylalanine, serine, histidine, cysteine, valine, methionine, isoleucine, leucine, hydroxyproline etc., and contain 20 kinds of metallic elements as potassium, sodium, calcium, magnesium, ferrum, copper molybdenum, strontium, barium isoreactivity composition; Nature and flavor are sweet, flat, return liver, lung, kidney channel; Energy tonifying blood and arresting bleeding, nourishing YIN and moistening the lung; Cure mainly dizziness due to deficiency of blood, haematemesis, epistaxis, have blood in stool, dysentery, gestation hemorrhage, metrorrhagia, fidgets due to deficiency insomnia, deficiency of the lung cough caused by dryness etc.; Modern pharmacology proves that Colla Corii Asini has the effects such as the hemopoietic of promotion, radioprotective, anoxia enduring, cold resistant, resisting fatigue, hemostasis, shock.
Herba Agrimoniae: be the aerial parts of Rosaceae Agrimony platymiscium Agrimony; Contain flavonoid as luteolin-7-glucoside, apigenin-7-glucoside, Quercetin, also contain the various active compositions such as rutin, kaempferol-7-rhamnoside, benzoaric acid, caffeic acid, gallic acid and match agrimophol A, B, C, D, E, F, G; Nature and flavor hardship, puckery, flat, return lung, liver, spleen channel; Energy astringing to arrest bleeding, removing food stagnancy dysentery relieving, removing toxic substances and promoting subsidence of swelling; Cure mainly spitting of blood, haematemesis, epistaxis, diarrhoea, dysentery, de-power impairment caused by overstrain, malaria, furuncle carbuncle etc.; Modern pharmacology proves that Herba Agrimoniae has the effects such as antitumor, parasiticide, blood sugar lowering.
Colla cornus cervi (white glue, Colla cornus cervi): the angle that belongs to animal Cervus nippon Temminck or Cervus elaphus linnaeus for Cervidae deer decocts the blob of viscose of making; The angle of Cervus nippon Temminck or Cervus elaphus linnaeus decocts the blob of viscose forming, and composition is similar to Cornu Cervi, mainly containing colloid, calcium phosphate, calcium carbonate etc.; Nature and flavor are sweet, salty, and temperature is returned liver, kidney channel; Energy the kidney invigorating and essence nourishing, nourishing blood and preventing abortion, hemostasis; Cure mainly asthenia weakness and emaciation, dizziness and tinnitus, soreness of the waist and knees, sexual impotence spermatorrhea, infertility, frequent fetal movement, bleeding not during menses, haematemesis, epistaxis, hemoptysis, hematuria, carbuncle of yin nature etc.
Radix Codonopsis: be the root of campanulaceae Codonopsis plant Radix Codonopsis, element flower Radix Codonopsis, radix codonpsis tangshen, pipe flower Radix Codonopsis, C. subglobosa, C. canescens; Contain saccharide as fructose, inulin, polysaccharide and 4 kinds of heteropolysaccharide CP 1, CP 2, CP 3, CP 4glycoside is as ligustrin, n-hexyl-β-pyranglucoside, ethyl-α-D-fructofuranoside, tangshenoside, alkaloid and nitrogen containing component, as choline, loline etc., also contain the various active compositions such as syringic aldehyde, vanillic acid, pyromucic acid, atractyloide I, II; Radix Codonopsis nature and flavor are sweet, flat, return spleen, lung meridian; Energy strengthening the spleen and tonifying the lung, supplementing QI for promoting the production of body fluid; Cure mainly weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung breath with cough, breathe hard spontaneous perspiration, all cards of deficiency of both QI and blood; Modern pharmacology proves that Radix Codonopsis has enhancing body stress ability, enhancing human body immunity function, slow down aging, antiulcer, antitumor assosting effect etc.
The Rhizoma Atractylodis Macrocephalae: be the rhizome of the Compositae [WTBX plant Rhizoma Atractylodis Macrocephalae; Contain volatile oil as atractylone, α and β-Humuleno, α-curcumene, Palmic acid, hinesol etc., sesquiterpene lactones compound is as atractyloide-I, II, III, IV etc., polyacetylene alcohol compound, also contain scopoletin, there is immunocompetent mannan AM-3, and more than ten seed amino acids such as aspartic acid, serine; Rhizoma Atractylodis Macrocephalae nature and flavor hardship, sweet, temperature, returns spleen, stomach warp; Energy invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive; Cure mainly deficiency-weakness of spleen-QI weak, lack of appetite abdominal distention, have loose bowels, dysuria of constipation, fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, Korean style numbness, general pain, spontaneous sweating due to deficiency of QI etc.; Modern pharmacology proves the effects such as the Rhizoma Atractylodis Macrocephalae has antioxidation and slow down aging, antitumor, blood sugar lowering, diuresis and anti-ascites, protects the liver, function of gallbladder promoting, can also facilitating digestion system, immune system, cardiac muscle and cardiovascular system.
Radix Paeoniae Rubra: be the root of Paeoniaceae Paeonia plant peony, river Radix Paeoniae Rubra; Contain monoterpenes as Radix Paeoniae Rubra glycosides, oxidation Radix Paeoniae Rubra glycosides etc., organic acid, as benzoic acid, gallic acid etc., also contains the plurality of active ingredients such as catechin, cupreol; Nature and flavor hardship, be slightly cold, return Liver Channel; Energy clearing away heat and cooling blood, clots absorbing pain relieving, dissipating blood stasis for subsidence of swelling; Cure mainly amenorrhea dysmenorrhea, hernia abdominal mass is gathered, maculae caused by violent heat pathogen, hematemesis and epistaxis, hypochondriac pain due to stagnation of liverQI, discharging fresh blood stool, conjunctival congestion and swelling pain, injury from falling down, carbuncle skin infection, can be used for the diseases such as amenorrhea; Modern pharmacology proves that Radix Paeoniae Rubra has antithrombotic, antiplatelet aggregation, arteriosclerosis, the effect such as protects the liver.
Radix Angelicae Sinensis: be the root of Umbelliferae archangel Radix Angelicae Sinensis; Contain multiple volatile oil and organic acid, also contain more than 20 kind of inorganic elements and polysaccharide composition; Nature and flavor are sweet, pungent, bitter, and temperature is returned liver, the heart, spleen channel; Can enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturizes laxation; Cure mainly all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia, heavy after bloody dysentery, ulcer sores, injury from falling down etc.; Modern pharmacology proves that Radix Angelicae Sinensis can affect blood and hemopoietic system, has the effects such as blood fat reducing, arteriosclerosis, radioprotective, antitumor, anti-inflammatory and antalgic and anti-damage.
Fructus Mori (Mulberry is real): be the dry fruit ear of Moraceae Morus plant Mulberry; Contain vitamin B 1, B 2and carotene, fatty acid is as linoleic acid, oleic acid, palmitic acid, stearic acid etc., and in quintessence oil, containing cineole, linalyl-acetate, linalool, Camphora, limonene etc., phospholipid is as various active compositions such as phosphatidylcholine, LYSO-PHOSPHATIDYLCHOLINE LYSOPC, phosphatidic acid; Nature and flavor are sweet, sour, cold, return liver, kidney channel; Can nourishing YIN and benefiting blood, promote the production of body fluid, intestine moistening; Cure mainly the having a dizzy spell of deficiency of the liver and kindey and blood deficiency damage of essence, tinnitus, early whitening of beard and hair, have a sleepless night, quench one's thirst, soreness of waist, dryness of the intestine, constipation, tinea alba etc.; Modern pharmacology proves that Fructus Mori is to immunologic function, hemopoietic function, Na +, K +-atpase activities etc. have regulating action.
The Rhizoma Anemarrhenae: be the rhizome of the Liliaceae Anemarrhena plant Rhizoma Anemarrhenae; Contain the various active compositions such as steroidal saponin, flavonoid, polysaccharide, choline; Nature and flavor hardship, cold lung, stomach, the kidney channel of returning; Energy clearing away heat-fire, preventing phlegm from forming and stopping coughing, nourshing Yin and drynsessmoistening prescription; Cure mainly calentura high fever excessive thirst, cough due to lung-heat, laryngopharynx swelling and pain, osteopyrexia and fever, restlessness of asrhenia type and insomnia, quench one's thirst stranguria with turbid discharge, constipation etc.; Modern pharmacology proves that the Rhizoma Anemarrhenae has the effects such as resisting pathogenic microbes, antiinflammatory, antitumor.
Herba Hedyotidis Diffusae: be the herb of Rubiaceae plants of Hedyotis Herba Hedyotidis Diffusae; Herb is containing asperuloside, organic acid and esters thereof are as asperuloside acid, deacetylate asperuloside acid, Herba Paederiae time glycosides, Herba Paederiae time glycosides methyl ester etc., Anthraquinones is as 2-methyl-3-hydroxyanthraquinone, 2-methyl-3-methoxyl group anthraquinone etc., triterpenes is as ursolic acid, oleanolic acid, stigmasterol etc., the various active compositions such as flavonoid; Nature and flavor hardship, sweet, cold, GUIXIN, lung, liver, large intestine channel; Energy heat-clearing and toxic substances removing, promoting blood circulation and detumescence, dampness removing jaundice eliminating; Cure mainly dyspnea and cough due to lung-heat, lung abscess, laryngopharynx swelling and pain, acute appendicitis, furuncle and phyma skin infection, venom, the puckery pain of pyretic stranguria, edema, dysentery enteritis, jaundice due to damp-heat, cancerous protuberance etc.; Modern pharmacology proves that Herba Hedyotidis Diffusae has antitumor, antioxidation, can regulate immunologic function, protection gastric mucosa injury etc.
Fructus Psoraleae: be the fruit of pulse family Psoralea plant Fructus Psoraleae, contain Coumarins as psoralen, isopsoralen (being Radix Angelicae Dahuricae element), xanthotoxin, psoralidine, isopsoralidine, Psoralen, Fructus Psoraleae tonkabean oestrane A and B, neo-psoralen etc., Flavanones is as Fructus Psoraleae flavanone, different Fructus Psoraleae flavanone, Fructus Psoraleae flavanone methyl ether etc., chalcone is as Corylifolinin, Bavachalcone, bavachromene etc., monoterpene phenols is as Bakuchiol, also contain Fructus Psoraleae polysaccharide and potassium, manganese, calcium, ferrum, copper, zinc, the elements such as antimony, fatty acid is as Palmic acid, oleic acid, linoleic acid, stearic acid, the various active compositions such as linolenic acid, nature and flavor acrid, bitter, warm, returns kidney, spleen channel, energy reinforcing the kidney and supporting YANG, warm spleen antidiarrheal, cure mainly sweating due to debility lumbago, chronic diarrhea, breathe heavily void, vitiligo, alopecia areata, psoriasis etc., modern pharmacology proves that Fructus Psoraleae has the effects such as antitumor, short melanin generation, antipathogen.
Radix Scutellariae: be the root of Labiatae Scutellaria plant Radix Scutellariae; Contain flavone compound as baicalin, skullcapflavone I, skullcapflavone II, baicalin, wogonin, chrysin etc., also contain the plurality of active ingredients such as cupreol, campesterol and stigmasterol; Radix Scutellariae nature and flavor hardship, cold; Return lung, the heart, liver, gallbladder, large intestine channel; Energy clearing away heat-fire, dampness removing toxic substances, hemostasis, antiabortive; Cure mainly cough due to lung-heat, calentura unconsciousness due to high fever, liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria, tells nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.; Modern pharmacology proves that Radix Scutellariae has the effects such as antimicrobial, antioxidation, anticancer, blood pressure lowering, diuresis, blood fat reducing, protection ischemical reperfusion injury.
Rhizoma Coptidis: be the rhizome of Rhizoma Imperatae section coptis plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao or Coptis teeta; Contain alkaloids as various active compositions such as berberine, coptisine, epiberberine, obacunone; Rhizoma Coptidis nature and flavor hardship, cold, GUIXIN, liver, stomach, large intestine channel; Energy clearing away heat-fire, dampness, removing toxic substances; Cure mainly the high heat that calentura heresy enters heart channel, agitation, the damp and hot feeling of stuffiness in chest, has loose bowels, dysentery, the vexed insomnia of hyperactivity of heart-fire, gastropyretic vomiting, rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain, and pathopyretic ulcer, furunculosis septicemia, gingival swelling and pain, aphtha of the mouth and tongue, hemorrhoidal bleeding, eczema, scalds etc.; Modern pharmacology proves that Rhizoma Coptidis exerts an influence to blood circulation, nervous system, also has the effects such as antimicrobial, protozoacide, antiulcer, antiviral, antiinflammatory, antitumor, blood sugar lowering, anticoagulant.
Folium Isatidis: be the leaf of Cruciferae Isatis indigotica Fort. platymiscium Isatis indigotica Fort.; Contain the plurality of active ingredients such as indigo, Isatis indigotica Fort. glycosides, indirubin, rosasterol; Nature and flavor hardship, cold; GUIXIN, stomach, liver, lung meridian; Energy heat-clearing and toxic substances removing, blood cooling and ecchymoses removing; Cure mainly the high hot excessive thirst of epidemic febrile disease, coma, macule, spits blood, epistaxis, jaundice, dysentery, erysipelas, sore throat, aphtha, mumps etc.; Modern pharmacology proves that Folium Isatidis has the effects such as resisting pathogenic microbes, antiendotoxin, antioxidation.
Squama Manis: be the scale of Manidae Manis animal Manitis; Contain stearic acid, cholesterol, N-butyl-23 (carbon) amide etc., again containing 18 kinds of elements such as zinc, sodium, titanium, calcium, lead, silicon, separately contain 16 kinds of free amino acids such as aspartic acid, threonine, serine, glutamic acid, glycine, alanine, cysteine, and the various active composition such as volatile oil and water-soluble alkaloid; Nature and flavor are salty, be slightly cold, and return liver, stomach warp; Energy promoting blood circulation to restore menstrual flow, stimulating milk secretion, eliminating carbuncle; Cure mainly blood stasis amenorrhea, mass in the abdomen, rheumatic arthralgia, carbuncle, scrofula etc.; Modern pharmacology proves that Squama Manis has anticoagulation, reduces the effects such as blood viscosity, antiinflammatory, and human peripheral blood flow and hypoxia-bearing capability have certain regulating action.
Radix Scrophulariae: be the root of Scrophulariaceae figwort Radix Scrophulariae and Radix Scrophulariae; The root of Radix Scrophulariae contains iridoid as Harpagide, rhinanthin, aucubin, Radix Scrophulariae cyclic ethers etc., also contain Radix Scrophulariae kind aglycon, Radix Scrophulariae kind glycosides A and B, the root of Radix Scrophulariae contains the various active compositions such as rhinanthin, methoxyl group rhinanthin, p-methoxycinnamate, peoniflorin; Nature and flavor are sweet, bitter, salty, are slightly cold, and return lung, stomach, kidney channel; Energy removing heat from blood, nourishing YIN to lower pathogenic fire, removing toxic substances; Cure mainly that warm febrile disease joins the army that blood, fever of the body, excessive thirst, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency are insomnia, constipation is hindered in Tianjin, puckery dim-sighted, the laryngopharynx swelling and pain of order, scrofula sucutaneous nodule, skin sore etc.; Modern pharmacology proves the effects such as Radix Scrophulariae has antipyretic, antibacterial, antiinflammatory, antioxidation, protects the liver, blood sugar lowering.
Cornu Bubali (husky Cornu Bovis seu Bubali): be the angle of Bovidae Bubalus animal Babalus bubalis L.; Contain the several amino acids such as cholesterol, heart tonifying composition, peptide class, angle fiber and serine, glycine, alanine, lysine, histidine, aspartic acid, arginine, threonine, glutamic acid, proline, cystine, methionine, isoleucine; Nature and flavor hardship, salty, cold; Energy heat clearing away, removing toxic substances, removing heat from blood, arresting convulsion; Cure mainly calentura headache, unconsciousness due to high fever, send out speckle dermexanthesis, haematemesis, epistaxis, stagnant heat jaundice, infantile convulsion and laryngopharynx swelling and pain, aphtha of the mouth and tongue etc.; Modern pharmacology proves that Cornu Bubali has the effects such as antiendotoxin is poisoning, calm, convulsion, analgesia, antiinflammatory, and cardiovascular system, immune system etc. are had to regulating action.
Caulis Spatholobi: be the rattan of pulse family spatholobus suberectus platymiscium spatholobus suberectus; Contain flavones ingredient as formoononetin, ononin, prunusetin., Licochalcone A etc., also contain Sitosterols composition as daucosterol, cupreol, 7-ketone group-cupreol etc., separately contain the various active compositions such as afromosin, Dai, epifriedelanol, epicatechin, 7-hydroxy-11,12-(methylenedioxy)coumestan, protocatechuic acid, 9-methoxyl group coumestrol; Nature and flavor hardship, micro-sweet, temperature, returns liver, kidney channel; Energy relaxing muscles and tendons to promote blood circulation, nourishing blood for regulating menstruation; Cure mainly numb hand and foot, quadriplegia, rheumatic arthralgia, anemia etc.; Modern pharmacology proves that Caulis Spatholobi has the blood vessel of expansion, antiplatelet aggregation, hemopoietic system, promotes the effects such as phosphorus metabolism.
Poria: be the sclerotium of the sleeping hole of Polyporaceae genus fungus Poria; Contain triterpenes as pachymic acid, 16 Alpha-hydroxy eburicoic acids, β-para hydroxybenzene acyl group dehydroeburicoic acid etc., polysaccharide is as the callose of pachyman, pachymaran and height, branch etc., also contains the various active compositions such as ergosterol, sad, hendecanoic acid, lauric acid, dodecenoic acid, Palmic acid, dodecenoic acid fat, sad fat and inorganic elements; Nature and flavor are sweet, light, flat, GUIXIN, spleen, lung, kidney channel; Energy promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming; Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, have loose bowels, palpitation and restlessness, insomnia forgetfulness etc.; Modern pharmacology proves that Poria has diuresis, anticancer and immunological enhancement etc.
Radix Aconiti Lateralis Preparata: be Ranunculaceae aconitum plant lateral root without a head (daughter root); Contain alkaloids as various active compositions such as aconitine, mesaconitine, hypaconitine, talastisamine higenamine are between racemization demethyl Quzhou coclaurine, coryneine chloride, different Radix Consolidae, benzoylmesaconitine, Xin Wuning alkali, the peaceful alkali of Radix Aconiti Lateralis Preparata, septentrionaline, karacoline, deoxyaconitine, Fuzitine alkali; Nature and flavor are pungent, sweet, and heat is poisonous, GUIXIN, kidney, spleen channel; Energy recuperating depleted YANG and rescuing the patient from collapse, dispelling cold and removing dampness; Cure mainly excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea and faint that contrary, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, carbuncle of yin nature skin ulcer are leaked and the disease of all chronic diseaseses; Modern pharmacology proves that Radix Aconiti Lateralis Preparata has the effects such as anti-myocardial ischemina, shock, antiinflammatory, tumor suppression, and cardiovascular system, blood system, central nervous system, immunologic function etc. are had to regulating action.
Fructus Jujubae: be the fruit of Rhamnaceae jujube Fructus Jujubae; Fruit contains alkaloid as stepharine, N-demethyl Folium Nelumbinis, asimilobine, Si Tefaling, N-nornuciferine, asimilobrine etc., triterpene acids is as Betulonic acid, oleanolic acid, maslinic acid etc., saponins is as Fructus Jujubae saponin i, II, III and Jujuboside B etc., fatty acid is as oleic acid, polysaccharide is as arabinan and galacturonic acid polysaccharide, sterols, as sitosterol, stigmasterol and a small amount of desmosterol etc., also contains the various active compositions such as rutin, vitamin C and riboflavin, thiamine, carotene, nicotinic acid; Nature and flavor are sweet, warm, GUIXIN, spleen, stomach warp; Energy tonifying the spleen and stomach, replenishing QI and blood, tranquilizing mind, tune Ying Wei and the property of medicine; Cure mainly weakness of the spleen and stomach, insufficiency of vital energy and blood, anorexia and loose stool, fatigue and weakness, palpitation and insomnia, woman hysteria, disharmony of nutrient QI with defensive QI etc.; Modern pharmacology proves that Fructus Jujubae has the effects such as maincenter inhibition, hepatoprotective, muscle strength reinforcing, antioxidation and slow down aging, antitumor.
Radix Glycyrrhizae: be the root and rhizome of pulse family glycyrrhiza genus Radix Glycyrrhizae, smooth bark Radix Glycyrrhizae, Glycyrrhiza inflata Bat.; Contain triterpene saponin as glycyrrhizin, Glycyrrhiza uralensis Fisch. saponin A, B etc., flavone compound is as 4',7-Dihydroxyflavanone, liquirtin etc., coumarin kind compound is as glycycoumarin, glycyol etc., alkaloids is as quinolines, iloquinoline derivative etc., polysaccharide, as Radix Glycyrrhizae glucosan GBW, Angelica Polysaccharide UA, UB, UC etc., also contains the plurality of active ingredients such as Radix Glycyrrhizae phenylpropyl alcohol furan, n-tricosane; Nature and flavor are sweet, flat, return spleen, stomach, the heart, lung meridian; Energy and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription; Process with controlling weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough, raw with controlling laryngopharynx swelling and pain, carbuncle pyogenic infections from tumour or sore, infantile carbuncle and medicine, alimentary toxicosis etc.; Modern pharmacology proves the effects such as Radix Glycyrrhizae has antimicrobial, antiinflammatory, antitussive, eliminates the phlegm, antitumor, mutation, antioxidation, and digestive system, cardiovascular system, reproductive system and brain, renal function etc. are had to regulating action.
Semen sojae atricolor face (Semen sojae atricolor, Semen sojae atricolor): the face of wearing into for the black seed of pulse family soybean plants Semen sojae atricolor; Contain protein, fat and carbohydrate, carotene, vitamin B 1and B 2, nicotinic acid etc., also contain flavonoid as daiazi, fire-bote glycosides, saponins is as soyasapogenol A-E, and the sugar of being combined with aglycon has glucose, xylose, galactose, arabinose, rhamnose etc., separately contains choline, folic acid, folinic acid, pantothenic acid, biotin, sialic acid, vitamin B 12etc. various active composition; Nature and flavor are sweet, flat, return spleen, kidney channel; Can activating blood and promoting diuresis, removing toxic substances, tonifying speen and tonifying kidney dispel the wind; Cure mainly edema, jaundice, beriberi, migratory arthralgia clonic spasm of the muscle, puerperal puerperal tetanus, lumbago due to renal deficiency, carbuncle sore tumefacting virus, medicine and alimentary toxicosis etc.; Modern pharmacology proves that Semen sojae atricolor has estrogen, the effect of estrogen antagonist sample, can also blood fat reducing, atherosclerosis, prevent and treat the effects such as osteoporosis, antitumor, antioxidation and defying age, anti-diabetic and complication thereof, radioprotective, adjusting cardiovascular system.
Carnis Sus domestica: for Suidae pig belongs to the meat of animal pig; The lean meat of pig and fat meat is moisture content 53%, 5% approximately respectively, protein 16.7%, 2.2%, fat 28.8%, 90.8%, carbohydrate 1.1%, 0.8%, ash 0.9%, 0.1%, calcium 71mg%, 1mg%, phosphorus 177mg%, 26mg%, ferrum 2.4mg%, 0.4mg%; Nature and flavor are sweet, salty, are slightly cold, and return spleen, stomach, kidney channel; Can tonify deficiency, YIN nourishing, moisturize; Cure mainly weak weakness and emaciation, consumption of body fluid caused by febrile disease, cough caused by dryness, quench one's thirst, constipation etc.
Brown sugar (brown sugar (Saccharum Sinensis Roxb.)): be the juice in grass family saccharum plant cane stalk, through the refining redness of the skin or complexion crystalline solid forming; Nature and flavor are sweet, warm, return liver, spleen, stomach warp; Can spleen reinforcing delay liver, promoting blood circulation to remove blood stasis; Cure mainly disease that postpartum lochia can't go, xerostomia the vomit sound of vomiting, weakness with emaciation cold and heat etc.
Nodus Nelumbinis Rhizomatis: be the joint portion of Nymphaeceae nelumbium Rhizoma Nelumbinis stem; Contain winter amide and tannin; Nature and flavor are sweet, puckery, flat, return liver, lung, stomach warp; Can stop blooding by dissipating blood stasis; Cure mainly haematemesis, spitting of blood, hematuria, have blood in stool, dysentery, metrorrhagia etc.
One is used for the treatment of the hemopathic Chinese medicine composition of aplastic, can adopt conventional method to be prepared into granule, powder, pill, tablets and other formulations, and the present invention only provides respectively the preparation method of a kind of capsule and pill.
A kind of preparation method that is used for the treatment of the hemopathic Chinese medicine composition of aplastic, comprise the following steps: accurately get each crude drug according to parts by weight, at 200～250 DEG C, toast 15～30 minutes, cooling rear pulverizing, the medicated powder that sieves to obtain, dress capsule obtains capsule.
The usage of capsule and consumption: every 0.4g, each 11, every day 3 times, warm water delivery service after meal, one month is a course for the treatment of, can cure three to four courses for the treatment of.
A kind of preparation method that is used for the treatment of the hemopathic Chinese medicine composition of aplastic, comprise the following steps: accurately get each crude drug according to parts by weight, except brown sugar, Carnis Sus domestica, Semen sojae atricolor face, other crude drug toast 15～30 minutes at 200～250 DEG C, cooling rear pulverizing, medicated powder sieves to obtain, brown sugar, Carnis Sus domestica and Semen sojae atricolor flour broken after and medicated powder mix, make pill, dry and obtain pill.
The usage of pill and consumption: every ball 0.4g, each 11 balls, every day 3 times, warm water delivery service after meal, one month is a course for the treatment of, can cure three to four courses for the treatment of.
Beneficial effect of the present invention:
The present invention is used for the treatment of the hemopathic Chinese medicine composition of aplastic, according to monarch principle composition of prescription, in side, the Radix Astragali, the Radix Rehmanniae, Radix Rehmanniae Preparata, Fructus Ligustri Lucidi, Radix Polygoni Multiflori Preparata, Fructus Corni, Radix Salviae Miltiorrhizae, Semen Cuscutae, Carapax et Plastrum Testudinis, Radix Codonopsis, Fructus Mori, Squama Manis, Caulis Spatholobi, Carapax Trionycis (processed), Radix Angelicae Sinensis, Herba Agrimoniae are monarch drug, have effect of invigorating the kidney and spleen, strong liver, benefiting QI and nourishing blood, vital essence replenishing and marrow benifiting, excited hemopoietic function; Fructus Lycii, Herba Epimedii, Cortex Moutan, Cortex Lycii, Colla cornus cervi, the Rhizoma Atractylodis Macrocephalae, Herba Hedyotidis Diffusae, Fructus Psoraleae, Radix Scutellariae, Folium Isatidis, Radix Panacis Quinquefolii, Poria, Nodus Nelumbinis Rhizomatis are ministerial drug, have except hectic fever due to YIN-deficiency, antiinflammatory, stop blooding, enrich blood, stop blooding and do not stay the stasis of blood, removing heat from blood, promote hemopoietic function, improve effect of blood environment and nutriture; Herba Ecliptae, Colla Corii Asini, Radix Paeoniae Rubra, the Rhizoma Anemarrhenae, Rhizoma Coptidis, Radix Scrophulariae, Cornu Bubali, Radix Aconiti Lateralis Preparata are adjuvant drug, have heat clearing away dispel silt, anti-inflammation, and then improve effect of cellular immunization and humoral immune function; Fructus Jujubae, Radix Glycyrrhizae, brown sugar, Semen sojae atricolor face, Carnis Sus domestica, for making medicine, have increase drug effect, remove toxicity, impel effect of cell regeneration; All medicines share plays liver spleen kidney altogether with doctor, makes effect of hematopoietic stem cell functional rehabilitation.Be mainly used in treating aplastic hematopathy, can increase myeloid element, except hectic fever due to YIN-deficiency, Psoralen is added marrow, and the generation that is erythrocyte and CFU-E to grain has obvious facilitation, can accelerate generation, differentiation, the maturation of hematopoietic cell.In addition, this Chinese medicine composition can also improve immunologic function, reduces immune leucocyte and destroys, and stimulates and activates hematopoietic function, makes erythrocyte hemopoietic vigorous, promotes red, leukocytic generation, increases platelet counts, strengthens platelet function etc.
Above-mentioned each crude drug effect in we and effect are as follows:
Fructus Ligustri Lucidi: energy nourishing liver and kidney, there is increase coronary artery blood flow, improve immunologic function, excited hemopoietic function, increases leukocyte;
Herba Ecliptae: energy nourishing YIN and supplementing the kidney, cooling blood for hemostasis, the immune organ weight that can make animal degenerate returns to normally, and then improves cellular immunization and humoral immune function;
Radix Polygoni Multiflori Preparata: can strengthen immunologic function, promote erythrocytic generation;
Fructus Lycii: hemopoietic function is had to facilitation, can also defying age, the effect such as mutation, antitumor, anti-fatty liver and blood sugar lowering;
Radix Rehmanniae Preparata: sweet in the mouth, tepor, matter profit, the YIN nourishing of both having enriched blood, again can vital essence replenishing and marrow benifiting;
The Radix Rehmanniae: energy clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid;
Carapax et Plastrum Testudinis: energy YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone, controls deficiency of kidney yin, and hectic fever due to YIN-deficiency consumptive fever is spitted blood, epistaxis, chronic cough, seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN;
The Radix Astragali: have QI invigorating, nourish blood, effect in benefit, the effect of enhancing human body immunity power, improves blood circulation and nutriture;
Fructus Corni: have liver and kidney tonifying, effect of essence astringing and desertion stemming, has antiinflammatory, antibacterial, the hemostasis effect of warp admittedly;
Herba Epimedii: beneficial vital essence, effect of hard muscles and bones, benefit waist knee joint, heart tonifying power;
Cortex Moutan: heat clearing away, promoting blood circulation to remove blood stasis, gas medicine in blood, adjust blood gas from and, regulating QI blood from peace;
Cortex Lycii: the medicine of tonifying YIN removing heat from blood, goes Liver and kidney deficiency-heat;
Carapax Trionycis (processed): nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, can suppress the connective tissue proliferation of liver, spleen, improves plasma protein level, and the effect such as antitumor;
Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling and removing heat from blood, Herba Ecliptae replenishing kidney-YIN, cooling blood for hemostasis, two medicines match, regulating nutrient QI and blood, hemostasis and do not stay the stasis of blood, removing heat from blood and can YIN nourishing;
Semen Cuscutae: nourishing the liver and kidney, can make the vigor of leukocyte count, RBC number, hemoglobin and superoxide dismutase significantly increase;
Radix Panacis Quinquefolii: there is YIN nourishing and QI supplementing, the mind calming and mentality promoting and clearing away heat and promoting production of body fluid, the effect of resisting fatigue, antioxidation, anti-stress, anticoagulant, reduction blood coagulation, promotes Growth of red blood cells, increases the deal of hematochrome;
Colla Corii Asini: nourishing YIN and supplementing blood, control blood deficiency, cough due to consumptive disease, spits blood, epistaxis, has blood in stool, menoxenia;
Herba Agrimoniae: astringing to arrest bleeding, has heart tonifying, rises blood pressure, blood coagulation, hemostasis, removing heat from blood, the effect such as antibacterial, compatibility Colla Corii Asini, Nodus Nelumbinis Rhizomatis, Radix Panacis Quinquefolii astringing to arrest bleeding; Colla Corii Asini nourishing YIN and moistening the lung, tonifying blood and arresting bleeding; The Nodus Nelumbinis Rhizomatisization hemostasis of becoming silted up. three's 5 use, hemostasis and do not stay silt; There is effect of nourishing YIN and moistening the lung, blood stanching, stasis transforming;
Colla cornus cervi: energy temperature compensation Liver and kidney, benefiting essence-blood, hemostasis, for kidney yang deficiency, asthenia of essence and blood, weakness is become thin, and deficiency and coldness is spitted blood, metrorrhagia, hematurias etc., can promote the erythrocyte in peripheral blood, leukocyte, hematoblastic amount increases:
Radix Codonopsis: have invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting, enhancing immunity, blood vessel dilating, blood pressure lowering, improves microcirculation, strengthens the effect such as hemopoietic function;
The Rhizoma Atractylodis Macrocephalae: have invigorating the spleen and benefiting QI, effect of dampness diuretic, adjusts gastrointestinal motility function, antiulcer, protects the liver, the effect such as enhancing human body immunity function, anti-stress, enhancing hemopoietic function;
Radix Paeoniae Rubra: clearing away heat and cooling blood, eliminating stasis to stop pain;
Radix Angelicae Sinensis: regulate body's immunity, there is anticancer, the effect of invigorating blood circulation of enriching blood;
Fructus Mori: have the liver and the kidney tonifying, promote the production of body fluid moisturize, effect of nourishing YIN and supplementing blood, can promote the growth of erythrocyte, prevent leukopenia, the immunologic function of cell is had to significant facilitation;
The Rhizoma Anemarrhenae: clearing away heat-fire, promotes the production of body fluid and moisturizes;
Herba Hedyotidis Diffusae: heat-clearing and toxic substances removing, the immunity of energy enhancing body, the growth of inhibition tumor cell, has inhibitory action to pathogenic bacteria;
Fructus Psoraleae: nourishing the liver and kidney, warming the kidney to activate YANG, leads to the gate of vitality, warm public region, holds back spirit;
Radix Scutellariae: energy heat clearing and damp drying, removing heat from blood, removing toxic substances, de-etiolation subcutaneous ulcer;
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication, for damp and hot feeling of fullness, vomiting, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed;
Folium Isatidis: clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, dissipating blood stasis hemostasis, speckle removing;
Squama Manis: blood circulation promoting and dispersing pathogen accumulation, eliminating carbuncle is burst hard, relieves internal heat anticancer, and energy leukocyte increasing, the immune function of enhancing body;
Radix Scrophulariae: clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing, hard masses softening and resolving;
Cornu Bubali: heat clearing away, removing toxic substances, cooling blood for hemostasis, energy removing heat from blood is with the warm of stopping blooding, for a speckle, the epistaxis of bleeding due to blood-heat;
Caulis Spatholobi: enrich blood, invigorate blood circulation, dredging collateral, can make hemocyte increase, hemoglobin raises, and reticulocyte is recovered;
Poria: there is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming, can enhancing human body immunity function, antitumor and protect the liver dirty effect, can make leukopenia accelerate;
Radix Aconiti Lateralis Preparata: can on help heart-yang to promote blood circulation, lower kidney-replenishing, with benefit fire, is saved lost Yuanyang, guiding fire to origin;
Fructus Jujubae: there is the function of invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, the mitigation property of medicine, can improve body immunity, and can anticancer, promote leukocytic generation;
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription;
Semen sojae atricolor face: can remove interior free yl, antioxidation, the heat extraction that dispels the wind, adjust in the therapeutic method to keep the adverse QI flowing downwards, detoxify, be a kind of effectively the kidney invigorating product;
Carnis Sus domestica: replenishing kidney-YIN, blood enriching and dryness moistening, QI invigorating detumescence, the function of enhancing body;
Brown sugar: there is the effect of benefiting QI and nourishing blood, spleen invigorating warming the stomach, expelling wind and cold, blood circulation promoting and blood stasis dispelling, also can impel cell regeneration;
Nodus Nelumbinis Rhizomatis: can astringing to arrest bleeding, have hold concurrently can blood stasis dispelling, have hemostasis and do not stay the feature of the stasis of blood, strong waist kidney, the arteries and veins of invigorating blood circulation, loose all blood stasis, raw all fresh blood.
The preparation method that the present invention is used for the treatment of the hemopathic Chinese medicine composition of aplastic is simple, is made into capsule or pill is easy to carry, and is suitable for large-scale industrial production and application.
Detailed description of the invention
Following embodiment is only described in further detail the present invention, but does not form any limitation of the invention.
Embodiment 1
The present embodiment is used for the treatment of the hemopathic Chinese medicine composition of aplastic, crude drug by following parts by weight forms: 15 parts of Fructus Ligustri Lucidi, 25 parts of Herba Ecliptaes, 15 parts of Radix Polygoni Multiflori Preparata, 20 parts of Fructus Lycii, 10 parts, Radix Rehmanniae Preparata, 30 parts, the Radix Rehmanniae, 15 parts of Carapax et Plastrum Testudiniss, 25 parts of the Radixs Astragali, 10 parts of Fructus Corni, 15 parts of Herba Epimedii, 10 parts of Cortex Moutans, 15 parts of Cortex Lycii, 15 parts of Carapax Trionycis (processed)s, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Semen Cuscutae, 12 parts of Radix Panacis Quinquefoliis, 9 parts, Colla Corii Asini, 25 parts of Herba Agrimoniaes, 15 parts of Colla cornus cervis, 25 parts of Radix Codonopsis, 9 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Radix Paeoniae Rubra, 15 parts of Radix Angelicae Sinensis, 25 parts of Fructus Mori, 9 parts of the Rhizoma Anemarrhenaes, 25 parts of Herba Hedyotidis Diffusaes, 9 parts of Fructus Psoraleaes, 12 parts of Radix Scutellariaes, 6 parts of Rhizoma Coptidis, 20 parts of Folium Isatidiss, 15 parts of Squama Maniss, 15 parts of Radix Scrophulariaes, 6 parts of Cornu Bubalis, 30 parts of Caulis Spatholobis, 10 parts, Poria, 6 parts of Radix Aconiti Lateralis Preparatas, 15 parts of Fructus Jujubaes, 12 parts, Radix Glycyrrhizae, 50 parts, Semen sojae atricolor face, 100 parts of Carnis Sus domesticas, 15 parts, brown sugar, 15 parts of Nodus Nelumbinis Rhizomatis.
The preparation method that is used for the treatment of the hemopathic Chinese medicine composition of aplastic in the present embodiment, comprises the following steps: accurately gets each crude drug according to parts by weight, at 230 DEG C, toasts 20 minutes, and cooling rear pulverizing, the medicated powder that sieves to obtain, dress capsule obtains capsule.
Embodiment 2
The present embodiment is used for the treatment of the hemopathic Chinese medicine composition of aplastic, crude drug by following parts by weight forms: 20 parts of Fructus Ligustri Lucidi, 15 parts of Herba Ecliptaes, 25 parts of Radix Polygoni Multiflori Preparata, 15 parts of Fructus Lycii, 20 parts, Radix Rehmanniae Preparata, 20 parts, the Radix Rehmanniae, 25 parts of Carapax et Plastrum Testudiniss, 15 parts of the Radixs Astragali, 20 parts of Fructus Corni, 10 parts of Herba Epimedii, 15 parts of Cortex Moutans, 10 parts of Cortex Lycii, 25 parts of Carapax Trionycis (processed)s, 15 parts of Radix Salviae Miltiorrhizaes, 20 parts of Semen Cuscutae, 9 parts of Radix Panacis Quinquefoliis, 15 parts, Colla Corii Asini, 20 parts of Herba Agrimoniaes, 25 parts of Colla cornus cervis, 10 parts of Radix Codonopsis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Radix Paeoniae Rubra, 25 parts of Radix Angelicae Sinensis, 15 parts of Fructus Mori, 15 parts of the Rhizoma Anemarrhenaes, 15 parts of Herba Hedyotidis Diffusaes, 15 parts of Fructus Psoraleaes, 9 parts of Radix Scutellariaes, 12 parts of Rhizoma Coptidis, 15 parts of Folium Isatidiss, 25 parts of Squama Maniss, 10 parts of Radix Scrophulariaes, 12 parts of Cornu Bubalis, 20 parts of Caulis Spatholobis, 15 parts, Poria, 3 parts of Radix Aconiti Lateralis Preparatas, 25 parts of Fructus Jujubaes, 6 parts, Radix Glycyrrhizae, 100 parts, Semen sojae atricolor face, 50 parts of Carnis Sus domesticas, 25 parts, brown sugar, 9 parts of Nodus Nelumbinis Rhizomatis.
In the present embodiment, be used for the treatment of the preparation method of the hemopathic Chinese medicine composition of aplastic, comprise the following steps: accurately get each crude drug according to parts by weight, except brown sugar, Carnis Sus domestica, Semen sojae atricolor face, other crude drug toast 15 minutes at 230 DEG C, cooling rear pulverizing, medicated powder sieves to obtain, brown sugar, Carnis Sus domestica and Semen sojae atricolor flour broken after and medicated powder mix, make pill, dry and obtain pill.
Embodiment 3
The present embodiment is used for the treatment of the hemopathic Chinese medicine composition of aplastic, crude drug by following parts by weight forms: 15 parts of Fructus Ligustri Lucidi, 25 parts of Herba Ecliptaes, 15 parts of Radix Polygoni Multiflori Preparata, 15 parts of Fructus Lycii, 20 parts, Radix Rehmanniae Preparata, 25 parts, the Radix Rehmanniae, 25 parts of Carapax et Plastrum Testudiniss, 20 parts of the Radixs Astragali, 15 parts of Fructus Corni, 15 parts of Herba Epimedii, 12 parts of Cortex Moutans, 15 parts of Cortex Lycii, 20 parts of Carapax Trionycis (processed)s, 15 parts of Radix Salviae Miltiorrhizaes, 20 parts of Semen Cuscutae, 10 parts of Radix Panacis Quinquefoliis, 10 parts, Colla Corii Asini, 25 parts of Herba Agrimoniaes, 20 parts of Colla cornus cervis, 10 parts of Radix Codonopsis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Radix Paeoniae Rubra, 20 parts of Radix Angelicae Sinensis, 20 parts of Fructus Mori, 10 parts of the Rhizoma Anemarrhenaes, 25 parts of Herba Hedyotidis Diffusaes, 15 parts of Fructus Psoraleaes, 10 parts of Radix Scutellariaes, 6 parts of Rhizoma Coptidis, 20 parts of Folium Isatidiss, 20 parts of Squama Maniss, 10 parts of Radix Scrophulariaes, 9 parts of Cornu Bubalis, 25 parts of Caulis Spatholobis, 15 parts, Poria, 6 parts of Radix Aconiti Lateralis Preparatas, 20 parts of Fructus Jujubaes, 9 parts, Radix Glycyrrhizae, 50 parts, Semen sojae atricolor face, 50 parts of Carnis Sus domesticas, 15 parts, brown sugar, 12 parts of Nodus Nelumbinis Rhizomatis.
The preparation method that is used for the treatment of the hemopathic Chinese medicine composition of aplastic in the present embodiment, comprises the following steps: accurately gets each crude drug according to parts by weight, at 210 DEG C, toasts 25 minutes, and cooling rear pulverizing, the medicated powder that sieves to obtain, dress capsule obtains capsule.
Test example
33 patients are received, the capsule that adopts embodiment 3 to prepare, take medicine continuously 3～4 courses for the treatment of, wherein 30 patients return to one's perfect health, and the every numerical value of physiochemical indice reaches normal value, all the other 2 patients are except platelet value is slightly lower than below normal value, other indices numerical stabilities, in good condition, belong to recovery from illness category, only a Platelet is always lower than normal value, other indices numerical stabilities.Add up known, the present invention is used for the treatment of the hemopathic Chinese medicine composition of aplastic the hemopathic cure rate of aplastic is reached to 97%, and effective percentage reaches 100%.
Curative effect judging standard:
Effective: condition of illness alleviates, complete blood cell, erythrocyte, leukocyte all reach normal value, only not enough normal value of platelet, and integrality is good;
Cure: condition of illness disappears, and the every numerical value of physiochemical indice reaches normal value, recover completely.
Model case
Case 1: Wang, man, 35 years old, the hyperpyrexia that happens suddenly one day, had a large amount of epistaxis, and through treatment, low grade fever does not move back, and changes the place of examination to the People's Hospital of city, is diagnosed as aplastic anemia hematopathy, take a turn for the better to some extent through treatment, but outbreak repeatedly, hemoglobin is low to moderate below 30g/L, erythrocyte 1.0 × 10 12below/L, leukocyte 2.0 × 10 9/ L, platelet only reaches 18 × 10 9/ L.Then medical, take capsule prepared by the embodiment of the present invention 1, check that indices is normal, Rehabilitation through 3 months treatment blood items.Pay a return visit repeatedly, health is good.
Case 2: section certain, female, 34 years old, one day, prominent sense was weak, low grade fever, vertigo and tinnitus, menstrual blood volume is large, and with fever, green around the gills, the existing purpura in many places with it, there are petechia, many places, gingival hemorrhage in oxter, fail to respond to any medical treatment and change the place of examination to the People's Hospital of city through local hospital, be diagnosed as aplastic anemia hematopathy, hemoglobin 40g/L, erythrocyte is low to moderate 1.5 × 10 12below/L, leukocyte 2.5 × 10 9/ L, platelet only reaches 25 × 10 9/ L.Then medical, take pill prepared by the embodiment of the present invention 2, check that through the treatment blood items of 4 months indices is normal, Rehabilitation.Return visit is repeatedly without abnormal, and quality of life is good.
Case 3: Zhang, man, suffers from aplastic anemia hematopathy for 16 years old, does not feel any better through treatment for many years.Then medical, see patient's green around the gills, unable on foot, occur having blood in stool, through the Lactoferrin 35g/L that has a blood test, erythrocyte is low to moderate 1.2 × 10 12below/L, leukocyte 2.5 × 10 9/ L, platelet only reaches 15 × 10 9/ L, takes capsule prepared by the embodiment of the present invention 1, checks that indices is normal, Rehabilitation through the treatment blood item of more than four months.Return visit is repeatedly without abnormal, and health is good.
Case 4: Zhao, man, 26 years old, suffer from aplastic anemia hematopathy for many years, bad in the time of many hospitalize fashions, its hemoglobin 45g/L, erythrocyte is low to moderate 1.8 × 10 12below/L, leukocyte 3.0 × 10 9/ L, platelet only reaches 45 × 10 9/ L.With going to a doctor, take capsule prepared by the embodiment of the present invention 3, medication takes effect for 1 month, takes continuously blood item after 4 months and checks that indices is normal, pays a return visit repeatedly without abnormal.
Efficacy result is analyzed:
Patient takes dizziness in second day, weak alleviating, and amount of bleeding reduces; Take after 15 days, transfusion volume reduces, and extend the interval time of transfusing blood, and mental status takes a turn for the better, and hemorrhage situation disappears, purpura or ecchymosis dimness, and the red point after oxter and ear obviously reduces, and patient's fever, infection alleviate and eliminate gradually; After 30 days, patient's complete blood cell, hemoglobin obviously increase, and purpura or ecchymosis disappear, and more than hemoglobin rises to 50g/L, erythrocyte rises to 2.0 × 10 12more than/L, leukocyte can be raised to 2.5 × 10 9more than/L, platelet can be raised to 40 × 10 9more than/L, patient's states is good; After 60 days, hemopoietic function of bone marrow starts to recover, and starts to transfer to red system by original Huang system, has normal hemopoietic, and more than hemoglobin rises to 80g/L, erythrocyte rises to 2.5 × 10 12more than/L, leukocyte can be raised to 3.5 × 10 9more than/L, platelet can be raised to 70 × 10 9more than/L; After 90 days, patient's hematopoietic stem cell functional rehabilitation, accelerate generation, differentiation, the maturation of hematopoietic cell, make erythrocyte hemopoietic vigorous, promote red, leukocytic generation, platelet counts increases, it is respectively functional rehabilitation, last patient's erythrocyte, leukocyte reach normal value, and more than hemoglobin rises to 110g/L, erythrocyte rises to 3.5 × 10 12more than/L, leukocyte can be raised to 6.0 × 10 9more than/L, platelet reaches or approaches 100 × 10 9/ L, Rehabilitation.

Claims (4)

1. be used for the treatment of the hemopathic Chinese medicine composition of aplastic, it is characterized in that: the crude drug by following parts by weight forms: 15～20 parts of Fructus Ligustri Lucidi, 15～25 parts of Herba Ecliptaes, 15～25 parts of Radix Polygoni Multiflori Preparata, 15～20 parts of Fructus Lycii, 10～20 parts, Radix Rehmanniae Preparata, 20～30 parts, the Radix Rehmanniae, 15～25 parts of Carapax et Plastrum Testudiniss, 15～25 parts of the Radixs Astragali, 10～20 parts of Fructus Corni, 10～15 parts of Herba Epimedii, 10～15 parts of Cortex Moutans, 10～15 parts of Cortex Lycii, 15～25 parts of Carapax Trionycis (processed)s, 15～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Semen Cuscutae, 9～12 parts of Radix Panacis Quinquefoliis, 9～15 parts, Colla Corii Asini, 20～25 parts of Herba Agrimoniaes, 15～25 parts of Colla cornus cervis, 10～25 parts of Radix Codonopsis, 9～15 parts of the Rhizoma Atractylodis Macrocephalaes, 10～15 parts of Radix Paeoniae Rubra, 15～25 parts of Radix Angelicae Sinensis, 15～25 parts of Fructus Mori, 9～15 parts of the Rhizoma Anemarrhenaes, 15～25 parts of Herba Hedyotidis Diffusaes, 9～15 parts of Fructus Psoraleaes, 9～12 parts of Radix Scutellariaes, 6～12 parts of Rhizoma Coptidis, 15～20 parts of Folium Isatidiss, 15～25 parts of Squama Maniss, 10～15 parts of Radix Scrophulariaes, 6～12 parts of Cornu Bubalis, 20～30 parts of Caulis Spatholobis, 10～15 parts, Poria, 3～6 parts of Radix Aconiti Lateralis Preparatas, 15～25 parts of Fructus Jujubaes, 6～12 parts, Radix Glycyrrhizae, 50～100 parts, Semen sojae atricolor face, 50～100 parts of Carnis Sus domesticas, 15～25 parts, brown sugar, 9～15 parts of Nodus Nelumbinis Rhizomatis.
2. the hemopathic Chinese medicine composition of aplastic that is used for the treatment of according to claim 1, it is characterized in that: the crude drug by following parts by weight forms: 15 parts of Fructus Ligustri Lucidi, 25 parts of Herba Ecliptaes, 15 parts of Radix Polygoni Multiflori Preparata, 15 parts of Fructus Lycii, 20 parts, Radix Rehmanniae Preparata, 25 parts, the Radix Rehmanniae, 25 parts of Carapax et Plastrum Testudiniss, 20 parts of the Radixs Astragali, 15 parts of Fructus Corni, 15 parts of Herba Epimedii, 12 parts of Cortex Moutans, 15 parts of Cortex Lycii, 20 parts of Carapax Trionycis (processed)s, 15 parts of Radix Salviae Miltiorrhizaes, 20 parts of Semen Cuscutae, 10 parts of Radix Panacis Quinquefoliis, 10 parts, Colla Corii Asini, 25 parts of Herba Agrimoniaes, 20 parts of Colla cornus cervis, 10 parts of Radix Codonopsis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Radix Paeoniae Rubra, 20 parts of Radix Angelicae Sinensis, 20 parts of Fructus Mori, 10 parts of the Rhizoma Anemarrhenaes, 25 parts of Herba Hedyotidis Diffusaes, 15 parts of Fructus Psoraleaes, 10 parts of Radix Scutellariaes, 6 parts of Rhizoma Coptidis, 20 parts of Folium Isatidiss, 20 parts of Squama Maniss, 10 parts of Radix Scrophulariaes, 9 parts of Cornu Bubalis, 25 parts of Caulis Spatholobis, 15 parts, Poria, 6 parts of Radix Aconiti Lateralis Preparatas, 20 parts of Fructus Jujubaes, 9 parts, Radix Glycyrrhizae, 50 parts, Semen sojae atricolor face, 50 parts of Carnis Sus domesticas, 15 parts, brown sugar, 12 parts of Nodus Nelumbinis Rhizomatis.
3. a preparation method that is used for the treatment of the hemopathic Chinese medicine composition of aplastic as claimed in claim 1 or 2, it is characterized in that: comprise the following steps: accurately get each crude drug according to parts by weight, at 200～250 DEG C, toast 15～30 minutes, cooling rear pulverizing, the medicated powder that sieves to obtain, dress capsule obtains capsule.
4. a preparation method that is used for the treatment of the hemopathic Chinese medicine composition of aplastic as claimed in claim 1 or 2, it is characterized in that: comprise the following steps: accurately get each crude drug according to parts by weight, except brown sugar, Carnis Sus domestica, Semen sojae atricolor face, other crude drug toast 15～30 minutes at 200～250 DEG C, cooling rear pulverizing, medicated powder sieves to obtain, brown sugar, Carnis Sus domestica and Semen sojae atricolor flour broken after and medicated powder mix, make pill, dry and obtain pill.
CN201410005401.6A 2014-01-06 2014-01-06 Traditional Chinese medicine composition for treating aplastic anemia and preparation method Pending CN103961521A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410005401.6A CN103961521A (en) 2014-01-06 2014-01-06 Traditional Chinese medicine composition for treating aplastic anemia and preparation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410005401.6A CN103961521A (en) 2014-01-06 2014-01-06 Traditional Chinese medicine composition for treating aplastic anemia and preparation method

Publications (1)

Publication Number Publication Date
CN103961521A true CN103961521A (en) 2014-08-06

Family

ID=51231841

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410005401.6A Pending CN103961521A (en) 2014-01-06 2014-01-06 Traditional Chinese medicine composition for treating aplastic anemia and preparation method

Country Status (1)

Country Link
CN (1) CN103961521A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173644A (en) * 2014-08-22 2014-12-03 上海中医药大学附属岳阳中西医结合医院 Traditional Chinese medicine composition for treating aplastic anemia
CN104544168A (en) * 2014-12-29 2015-04-29 唐华 Health-care preparation for preventing and treating human iron deficiency, and preparation method of health-care preparation
CN104644631A (en) * 2015-01-31 2015-05-27 云南省第一人民医院 Change of mesaconitine to K562 cell biological characteristics
CN105616761A (en) * 2016-03-01 2016-06-01 青岛市中心医院 Traditional Chinese medicine preparation used for increasing leukocyte and blood platelet after radiation
CN106620437A (en) * 2016-08-25 2017-05-10 高志宏 Traditional Chinese medicine composition for treating blood diseases and method for preparing traditional Chinese medicine composition
CN109512915A (en) * 2017-09-18 2019-03-26 计怀安 Spot-eliminating beauty treatment ball
CN109908323A (en) * 2019-04-01 2019-06-21 李胜 A kind of compound product production method facilitated human bone marrow's stem cell regenerating and activate suspend mode stem cell
CN110274976A (en) * 2019-07-18 2019-09-24 长春中医药大学 A kind of rhododendron mariae Herbal HPLC Fingerprint construction method
CN112998257A (en) * 2021-03-29 2021-06-22 戴清桂 Dietetic therapy composition and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1071582A (en) * 1991-10-12 1993-05-05 龙孟麟 Aplastic anemia is converted into leukemia
CN1422628A (en) * 2001-12-04 2003-06-11 刘钦 Baixue-Genzhi-Changshoubao-Chinese medicine for treating leukemia and concurrently treating aplastic anemia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1071582A (en) * 1991-10-12 1993-05-05 龙孟麟 Aplastic anemia is converted into leukemia
CN1422628A (en) * 2001-12-04 2003-06-11 刘钦 Baixue-Genzhi-Changshoubao-Chinese medicine for treating leukemia and concurrently treating aplastic anemia

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173644A (en) * 2014-08-22 2014-12-03 上海中医药大学附属岳阳中西医结合医院 Traditional Chinese medicine composition for treating aplastic anemia
CN104544168A (en) * 2014-12-29 2015-04-29 唐华 Health-care preparation for preventing and treating human iron deficiency, and preparation method of health-care preparation
CN104644631A (en) * 2015-01-31 2015-05-27 云南省第一人民医院 Change of mesaconitine to K562 cell biological characteristics
CN105616761A (en) * 2016-03-01 2016-06-01 青岛市中心医院 Traditional Chinese medicine preparation used for increasing leukocyte and blood platelet after radiation
CN106620437A (en) * 2016-08-25 2017-05-10 高志宏 Traditional Chinese medicine composition for treating blood diseases and method for preparing traditional Chinese medicine composition
CN109512915A (en) * 2017-09-18 2019-03-26 计怀安 Spot-eliminating beauty treatment ball
CN109908323A (en) * 2019-04-01 2019-06-21 李胜 A kind of compound product production method facilitated human bone marrow's stem cell regenerating and activate suspend mode stem cell
CN110274976A (en) * 2019-07-18 2019-09-24 长春中医药大学 A kind of rhododendron mariae Herbal HPLC Fingerprint construction method
CN112998257A (en) * 2021-03-29 2021-06-22 戴清桂 Dietetic therapy composition and preparation method thereof

Similar Documents

Publication Publication Date Title
CN103961521A (en) Traditional Chinese medicine composition for treating aplastic anemia and preparation method
CN102698137B (en) Composition with blood pressure reducing function and preparation method of same
CN101502588B (en) Composition for beauty treatment and removing blain and method for preparing the same
CN104826033A (en) Traditional Chinese medicine composition for treating coronary heart disease and preparation method thereof
CN105250675A (en) Traditional Chinese medicine combination for preparing medicine for treating tumour and leukemia
CN103977368A (en) Traditional Chinese medicinal composition for treating arthralgia caused by rheumatic chills and fever and preparation method thereof
CN102526498A (en) Chinese medicine for eliminating toxic and side effects after nasopharyngeal carcinoma radiotherapy and preparation method and administration way thereof
CN104161977B (en) It is a kind of to be used to prevent and treat Chinese medicine composition of infectious coryza of chicken and preparation method thereof
CN104922426A (en) Pharmaceutical composition for treating post gynecologic operation low fever
CN102058775B (en) Health-care pressure-lowering tea and preparation method thereof
CN104208339A (en) Traditional Chinese medicine composition for treating livestock and poultry bacterial or viral diseases and preparation method thereof
CN106109521A (en) A kind of Radix Notoginseng oral liquid
CN105381267A (en) Traditional Chinese medicine composition for treating hypertension and oral preparation and preparation method thereof
CN105395842A (en) Traditional Chinese medicine composition for treating diabetes and oral preparation and preparation method thereof
CN102614466B (en) Traditional Chinese medical preparation for treatment of lung adenocarcinoma
CN102309620B (en) Chinese medicinal preparation for treating constipation and preparation method thereof
CN105169278A (en) Dandelion oral liquid capable of protecting liver and benefiting gallbladder and preparation method thereof
CN105106634A (en) Traditional Chinese medicine preparation for treating acute appendicitis and application thereof
CN104547803A (en) Traditional Chinese medicine composition for postpartum fevers of women for clearing away heat and toxic materials
CN110575466A (en) Composition for increasing bone mineral density and application thereof
CN105770760A (en) Preparation for treating gastric ulcer and preparation method thereof
CN105169275A (en) Rheum officinale oral liquid capable of protecting liver and benefiting gallbladder and preparation method thereof
CN105456933A (en) Traditional Chinese medicine capable of activating blood to remove stasis and clearing and activating channels and collaterals and preparation method of traditional Chinese medicine
CN105362961A (en) Traditional Chinese medicine pill used for treating premature ovary failure and preparation method
CN105169277A (en) Fructus gardeniae oral liquid capable of protecting liver and benefiting gallbladder and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20140806

RJ01 Rejection of invention patent application after publication