CN105395842A - Traditional Chinese medicine composition for treating diabetes and oral preparation and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating diabetes and an oral preparation and a preparation method thereof. The traditional Chinese medicine composition is prepared from, by mass, 15-45 parts of prepared rehmannia roots, 25-75 parts of sealwort, 15-45 parts of radix ophiopogonis, 20-60 parts of radix trichosanthis, 15-45 parts of rhizoma alismatis, 20-60 parts of poria cocos, 15-45 parts of rhizoma anemarrhenae,17-53 parts of Chinese yam, 15-45 parts of radix achyranthis bidentatae, 15-45 parts of cortex lycii radicis, 15-45 parts of cortex phellodendri, 20-60 parts of cornus officinalis, 15-45 parts of fruits of Chinese wolfberries, 12-38 parts of poria cocos different from the previous one, 10-30 parts of felwort, 15-45 parts of dahurian patrinia herbs, 20-60 parts of moutan bark, 15-45 parts of radix paeoniae alba, 17-53 parts of cistanche deserticola, 15-45 parts of locust beans, 20-60 parts of salvia miltiorrhiza and 15-45 parts of fructus ligustri lucidi. The medicine materials are used cooperatively and have the functions of reducing blood sugar, clearing away liver fire, treating consumptive thirst and tonifying the kidneys, and the traditional Chinese medicine composition has a remarkable curative effect on consumptive thirst symptoms (diabetes).

Description

A kind of Chinese medicine composition, oral formulations and preparation method thereof being used for the treatment of diabetes

Technical field

The invention belongs to technical field of traditional Chinese medicine, be specifically related to a kind of Chinese medicine composition being used for the treatment of diabetes, also relate to a kind of oral formulations being used for the treatment of diabetes and preparation method thereof simultaneously.

Background technology

Diabetes are because insulin in body is absolute or relative deficiency, cause the metabolism disorder of sugar, fat, protein, thus cause one group of endocrine metabolism syndrome; The metabolic disease of heat syndrome that to be a group with hyperglycemia be, hyperglycemia be then due to defect of insulin secretion or its biological agent impaired, or both have concurrently and cause.Long-standing hyperglycemia during diabetes, causes patient various tissue, particularly eye, kidney, heart, blood vessel, neural chronic lesion, dysfunction.The diagnosis of diabetes is generally: fasting glucose is more than or equal to 7.0 mM/ls, and/or two hours blood glucoses are more than or equal to 11.1 mM/ls and can make a definite diagnosis after the meal.Wherein, type 1 diabetes age of onset is light, mostly less than 30 years old, onset is unexpected, and polydipsia polyuria polyphagia becomes thin symptom obviously, and blood sugar level is high, many patients take ketoacidosis as onset symptoms, serum insulin and C peptide low SI, and ICA, IAA or GAD antibody can be positive; Singly take oral medicine invalid, need insulinize; Type 2 diabetes mellitus is common in middle-aged and elderly people, and overweight people's sickness rate is high, often can with diseases such as hypertension, high fat exception, arteriosclerosis.

The cause of disease of diabetes is mainly inherited genetic factors and environmental factors, and 1 type or type 2 diabetes mellitus all exist obvious genetic heterogeneity, there is family's morbidity tendency; And feed too much, it is the topmost environmental factorss of diabetes that physical exertion reduces the obesity caused.The clinical manifestation of diabetes is mainly: polydipsia, polyuria, polyphagia and become thin, and namely occurs typical " three-many-one-little " symptom during serious hyperglycemia, is more common in type 1 diabetes; Fatigue and weak, obesity are more common in type 2 diabetes mellitus; Type 2 diabetes mellitus premorbid often has obesity, if can not get timely diagnosis, body weight can decline gradually.Along with diabetic duration extend, the chronic complicating diseases of can occur together eye, nerve and the heart, brain, Shen Deng vascular tissue organ, this for diabetes disable, lethal principal element.

At present, the method mainly through Drug therapy controls diabetes, comprises oral drug therapy and insulinize.In oral drug therapy, sulfonylurea drugs stimulates insulin secretion, and to having, certain islet function person curative effect is better; The main mechanism of biguanides increases peripheral tissues to the utilization of glucose, increases the anerobic glycolysis of glucose, reduces gastrointestinal tract to the absorption of glucose, reduce body weight; α glucosidase inhibitor can with sulphanylureas, biguanides or insulin coupling; Insulin potentiators has enhancing insulin action, improves carbohydrate metabolism; The quick insulin secretion accelerating of meglitinide Insulin secretagogues, at once oral before the meal.Insulinize is for forcing injected Forms of Insulin, and the maximum untoward reaction of insulinize is hypoglycemia.

Although above-mentioned Therapeutic Method can control diabetes to a certain extent, no matter be that oral drug therapy or insulinize all have the following disadvantages: long-term treatment is easily put aside in vivo, and toxic and side effects is large, untoward reaction is many; Cause blood glucose fluctuated after treatment, wayward and adjustment; Need to treat for a long time, poor effect; Cost is high simultaneously, brings heavy financial burden to patient.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine composition being used for the treatment of diabetes, for by excessive rising of liver-YANG, the withered constipation in the Tianjin caused by insufficiency of kidney-YANG, soreness of the waist and knees; frequency of micturition, the symptom of quenching one's thirst (diabetes) of blood and essence asthenia has significant curative effect, treating both the principal and secondary aspects of a disease.

Second object of the present invention is to provide a kind of oral formulations being used for the treatment of diabetes.

3rd object of the present invention is to provide a kind of preparation method being used for the treatment of the oral formulations of diabetes.

In order to realize above object, the technical solution adopted in the present invention is:

A kind of Chinese medicine composition being used for the treatment of diabetes, be made up of the component of following mass fraction: Radix Rehmanniae Preparata 15 ~ 45 parts, Rhizoma Polygonati 25 ~ 75 parts, Radix Ophiopogonis 15 ~ 45 parts, Radix Trichosanthis 20 ~ 60 parts, Rhizoma Alismatis 15 ~ 45 parts, 20 ~ 60 parts, Poria, the Rhizoma Anemarrhenae 15 ~ 45 parts, Rhizoma Dioscoreae 17 ~ 53 parts, Radix Achyranthis Bidentatae 15 ~ 45 parts, Cortex Lycii 15 ~ 45 parts, Cortex Phellodendri 15 ~ 45 parts, Fructus Corni 20 ~ 60 parts, Fructus Lycii 15 ~ 45 parts, 12 ~ 38 parts, Poria, Radix Gentianae 10 ~ 30 parts, Herba Patriniae 15 ~ 45 parts, Cortex Moutan 20 ~ 60 parts, the Radix Paeoniae Alba 15 ~ 45 parts, Herba Cistanches 17 ~ 53 parts, Semen sophorae 15 ~ 45 parts, Radix Salviae Miltiorrhizae 20 ~ 60 parts, Fructus Ligustri Lucidi 15 ~ 45 parts.

Preferably, the described Chinese medicine composition being used for the treatment of diabetes, be made up of the component of following mass fraction: Radix Rehmanniae Preparata 27 ~ 33 parts, Rhizoma Polygonati 45 ~ 55 parts, Radix Ophiopogonis 27 ~ 33 parts, Radix Trichosanthis 36 ~ 44 parts, Rhizoma Alismatis 27 ~ 33 parts, 36 ~ 44 parts, Poria, the Rhizoma Anemarrhenae 27 ~ 33 parts, Rhizoma Dioscoreae 31 ~ 39 parts, Radix Achyranthis Bidentatae 27 ~ 33 parts, Cortex Lycii 27 ~ 33 parts, Cortex Phellodendri 27 ~ 33 parts, Fructus Corni 36 ~ 44 parts, Fructus Lycii 27 ~ 33 parts, 22 ~ 28 parts, Poria, Radix Gentianae 18 ~ 22 parts, Herba Patriniae 27 ~ 33 parts, Cortex Moutan 36 ~ 44 parts, the Radix Paeoniae Alba 27 ~ 33 parts, Herba Cistanches 31 ~ 39 parts, Semen sophorae 27 ~ 33 parts, Radix Salviae Miltiorrhizae 36 ~ 44 parts, Fructus Ligustri Lucidi 27 ~ 33 parts.

Preferred further, the described Chinese medicine composition being used for the treatment of diabetes, is made up of the component of following mass fraction: Radix Rehmanniae Preparata 30 parts, Rhizoma Polygonati 50 parts, Radix Ophiopogonis 30 parts, Radix Trichosanthis 40 parts, Rhizoma Alismatis 30 parts, 40 parts, Poria, the Rhizoma Anemarrhenae 30 parts, Rhizoma Dioscoreae 35 parts, Radix Achyranthis Bidentatae 30 parts, Cortex Lycii 30 parts, Cortex Phellodendri 30 parts, Fructus Corni 40 parts, Fructus Lycii 30 parts, 25 parts, Poria, Radix Gentianae 20 parts, Herba Patriniae 30 parts, Cortex Moutan 40 parts, the Radix Paeoniae Alba 30 parts, Herba Cistanches 35 parts, Semen sophorae 30 parts, Radix Salviae Miltiorrhizae 40 parts, Fructus Ligustri Lucidi 30 parts.

Of the present inventionly be used for the treatment of in the Chinese medicine composition of diabetes, the property of medicine drug effect of each Chinese medicinal components is as follows:

Radix Rehmanniae Preparata: be the tuber of Scrophulariaceae Radix Rehmanniae platymiscium Radix Rehmanniae, steams solarization through processing and forms; Containing effective ingredient such as Herba Leonuri glycosides, aucubin, catalpol, Martynoside., rehmanin, violet ketosides, sweet, warm, return lung, kidney channel.Effect is YIN nourishing of enriching blood, beneficial essence fills out marrow; Cure mainly blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, metrorrhagia is more than, hepatic and renal YIN deficiency, hectic fever night sweat, and seminal emission sexual impotence, infertility, soreness of the waist and knees, Hiccough and deaf, the head is dim-sighted, early whitening of beard and hair, quenches one's thirst, constipation, dyspnea with rapid and short breath of suffering from a deficiency of the kidney.Modern pharmacology research shows, Radix Rehmanniae Preparata has promotion medulla hematopoietic system function, resisting blood coagulation, raising function of immune system, improves the effect such as systema cariovasculare functional, antioxidation.

Rhizoma Polygonati: be the rhizome of Liliaceae HUANGJING ZANYU CAPSULE Rhizoma Polygonati, Polygonatum cyrtonema Hua and P. kingianum; Containing furan steroid enol form saponin and the effective ingredient such as spirostene alcohol type saponin and polygonatum polysaccharide; Sweet, flat, return spleen, lung, kidney channel.Effect is nourishing YIN and moistening the lung, invigorating the spleen and replenishing QI, Zishen fill fine; Cure mainly deficiency of YIN chronic cough, xeropulmonary cough, insufficiency of the spleen weak, lack of appetite xerostomia, quenches one's thirst, deficiency of the kidney soreness of the waist and knees, impotence and seminal emission, and tinnitus order is dark, and early whitening of beard and hair, body weakness with emaciation is weak, wind favus disease.Modern pharmacology research shows, Rhizoma Polygonati has resisting pathogenic microbes, raising systema cariovasculare functional, blood fat reducing, slow down aging, raising function of immune system, improves the effects such as learning and memory reproduction.

Radix Ophiopogonis: also known as Radix Ophiopogonis is the tuber of Liliaceae Ophiopogon plant Radix Ophiopogonis or dwarf lilyturf; Containing effective ingredient such as ophiopogonin, longifolene, Herba Pogostemonis alkene; Sweet, micro-hardship, is slightly cold, and returns lung, stomach, heart channel.Effect is nourishing YIN and moistening the lung, reinforcing stomach reg fluid, and clear away heart-fire relieving restlessness; Cure mainly dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, and quench one's thirst, vexed insomnia, has sore throat, and dryness of the intestine constipation, heat in blood tells nosebleed.Modern pharmacology research shows, has Radix Ophiopogonis and promotes cardiovascular system, arrhythmia, anoxia enduring, raising function of immune system, blood sugar lowering, scavenging free radicals, slow down aging, promotion gastrointestinal motility function, the effect such as antibacterial.

Radix Trichosanthis: be the root of Cucurbitaceae Trichosanthes Fructus Trichosanthis and Chinese Fructus Trichosanthis; Containing plurality of active ingredients such as protein, several amino acids and peptide class, sterol, fatty acids; Sweet, micro-hardship, is slightly cold; Attach to the lung and stomach meridians.Effect is clearing away heat and promoting production of body fluid, moistening the lung and resolving phlegm, detumescence and apocenosis; Cure mainly calentura thirsty, polydipsia of quenching one's thirst, lung-heat type cough, sore swollen toxin.Modern pharmacology research shows, Radix Trichosanthis has and causes miscarriage and the effect such as antiearly pregnancy, anticancer, Promote immunity systemic-function, AIDS virus resisting.

Rhizoma Alismatis: be the tuber of Alismataceae Waterplantain plant Rhizoma Alismatis; Containing alisol, alisol monoacetate, table alisol, also containing effective ingredient such as sesquiterpenoids, sitosterol, stearic acid, emodins; Sweet, light, cold, return kidney, urinary bladder channel.Effect is promoting diuresis to eliminate damp pathogen, expels the heat-evil treating stranguria; Cure mainly dysuria, the puckery pain of pyretic stranguria, edema distension, has loose bowels, dizziness due to fluid-retention, seminal emission.Modern pharmacology research shows, Rhizoma Alismatis has diuresis, promotes the effects such as systema cariovasculare functional, blood fat reducing, atherosclerosis, raising function of immune system, antiinflammatory, fat-reducing.

Poria: for Polyporaceae hole of crouching belongs to the sclerotium of fungus Poria; Containing triterpeness such as pachymic acid, pachymic acid methyl ester, also containing pachyman, pachymaran, ergosterol, the effective ingredient such as sad; Sweet, light, flat, GUIXIN, spleen, lung, kidney channel.Effect is promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming; Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, has loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine.Modern pharmacology research shows, Poria has the effects such as diuresis, facilitating digestion systemic-function, anticancer, immunostimulant.

The Rhizoma Anemarrhenae: be the rhizome of the Liliaceae Anemarrhena plant Rhizoma Anemarrhenae; Containing timosaponin, anemaran, plurality of active ingredients such as fruit glycosides, nicotinic acid etc.; Property bitter, cold, return lung, stomach, kidney channel.Effect is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription; Cure mainly epidemic febrile disease, high hot excessive thirst, cough due to lung-heat, osteopyrexia and fever, night sweat, restlessness of asrhenia type and insomnia, quenches one's thirst.Modern pharmacology research proves that the Rhizoma Anemarrhenae has suppression Na ⁺, K ⁺and the effect such as atpase activity, blood sugar lowering, antiplatelet aggregation, resisting pathogenic microbes, antiinflammatory, antitumor.

Rhizoma Dioscoreae: be the tuber of Dioscoreaceae yam Rhizoma Dioscoreae; Containing diosgenin, dopamine, hydrochloric acid Rhizoma Dioscoreae alkali, allantoin and the effective ingredient such as several amino acids, trace element; Sweet, flat, return spleen, lung, kidney channel.Effect be spleen reinforcing, support lung, reinforce the kidney, benefit essence; Cure mainly diarrhea due to hypofunction of the spleen, lack of appetite edema, cough and asthma due to lung deficiency, quenches one's thirst, seminal emission, leukorrhagia, frequent micturition of suffering from a deficiency of the kidney; Carbuncle is controlled in external, scrofula.Modern pharmacology research shows, Rhizoma Dioscoreae has blood sugar lowering, facilitating digestion systemic-function, improves the effects such as immunologic function, antioxidant activity, blood fat reducing.

Radix Achyranthis Bidentatae: be the root of Amaranthaceae Achyranthes plant Radix Achyranthis Bidentatae; Containing triterpene saponin as radix achyranthis bidentatae saponin, ginsenoside, Rhizoma Panacis Japonici saponin etc., also containing plurality of active ingredients such as polysaccharide, ketosteroid, aminoacid, protein.Property bitter, acid, flat, return liver, kidney channel; Effect is invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, draws blood (fire) descending, inducing diuresis for treating stranguria syndrome; Cure mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis ， WEIJIA, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain.Modern pharmacology research shows, Radix Achyranthis Bidentatae has antalgic and inflammation relieving, improves cardiovascular and Respiratory ft tive resistance, antifertility, blood sugar lowering, raising function of immune system, slow down aging, antineoplastic action.

Cortex Lycii: be the root bark of Solanaceae Lycium Fructus Lycii, lycium barbarum; Containing effective ingredient such as the alkaloids such as betanin, organic acid, lyciumamide, linolenic acid, melissic acid, cinnamic acid, cryptojaponols; Sweet, cold, return lung, kidney channel.Effect is clearind deficient heat, purte the white, removing heat from blood; Cure mainly hectic fever due to deficiency of YIN, hectic fever due to YIN-deficiency night sweat, infantile malnutrition generates heat, dyspnea and cough due to lung-heat, and spit blood, epistaxis, hematuria, quenches one's thirst.Modern pharmacology research shows, Cortex Lycii has the effects such as antipyretic, blood pressure lowering, blood sugar lowering.

Cortex Phellodendri: be the bark of Rutaceae Phellodendron plant wampee or Cortex Phellodendri; Containing alkaloids as berberine, phellodendrine, magnoflorine, also containing effective ingredient such as obakulactone, obacunone, sitosterol, stigmasterol; Hardship, cold, return kidney, bladder, large intestine channel.Effect is heat clearing and damp drying, eliminating fire and detoxication; Cure mainly hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema.Modern pharmacology research shows, Cortex Phellodendri has the effect such as resisting pathogenic microbes, antipyretic and antiinflammatory, promotion systema cariovasculare functional, digestion promoting, antiplatelet aggregation.

Fructus Corni: be the sarcocarp of Cornaceae Macrocarpium plant Fructus Corni; Containing effective ingredient such as Fructus Corni tannin, cornusiin, clove tree tannin, gallic acid, polyphenol glycoside compound, cornuside, morronisides; Acid, tepor, returns liver, kidney channel.Effect is liver and kidney tonifying, convergence is solid takes off; Cure mainly and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding.Modern pharmacology research shows, Fructus Corni has raising function of immune system, antiinflammatory, alleviates hemorrhagic shock, blood sugar lowering, anticoagulant, promotion cardiac function and the effect such as hemodynamics, arrhythmia.

Fructus Lycii: be the fruit of Solanaceae Lycium lycium barbarum; Containing effective ingredient such as betanin, atropine, hyoscyamine, Allylamines, polysaccharide, cerebroside, ursolic acid, Semen Maydis xanthin, physalin, kryptoxanthin, scopoletin, P-coumaric acid, daucosterols; Sweet, flat, return liver, kidney, lung meridian.Effect is nourishing the liver, nourishing kidney, lung moistening; Cure mainly caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, taking fluids profusely of quenching one's thirst.Modern pharmacology research shows, Fructus Lycii have improve immunologic function, slow down aging, antitumor, blood fat reducing and protect the liver, anti-fatty liver, raising hemopoietic system function, anti-damage of genetic materials, blood sugar lowering, blood pressure lowering, the effect such as antibacterial.

Poria: for Polyporaceae hole of crouching belongs to the sclerotium of fungus Poria; Containing triterpeness such as pachymic acid, pachymic acid methyl ester, also containing pachyman, pachymaran, ergosterol, the effective ingredient such as sad; Sweet, light, flat, GUIXIN, spleen, lung, kidney channel.Effect is promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming; Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, has loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine.Modern pharmacology research shows, Poria has the effects such as diuresis, facilitating digestion systemic-function, anticancer, immunostimulant.

Radix Gentianae: also known as Radix Gentianae is the root welding technology of Gentianaceae agueweed Radix Gentianae, Gentiana manshurica, G. triflora and Yunnan Radix Gentianae; Containing Secoiridoid Glycosides bitter principle as gentiopicrin, sweroside, alkaloid, as erythricine, gentioflavine, also contains the effective ingredient such as triterpenes; Hardship, cold, return liver, gallbladder meridian.Effect is liver heat removing gallbladder excess-fire, rushes down damp-heat in lower-JIAO; Cure mainly feeling of fullness in the head headache, conjunctival congestion and swelling pain, deaf ear swells, bitter taste in the mouth and pain in the hypochondrium; Jaundice due to damp-heat, urine leaching pain, swelling of the vulva pudendal pruritus, leukorrhagia, calentura convulsion with spasms.Modern pharmacology research shows, Radix Gentianae have protect the liver, function of gallbladder promoting, stomach invigorating, antiinflammatory, antiallergic, the effect such as promotion central nervous system function.

Herba Patriniae: also known as Herba Patriniae is the herb of Valerianaceae Patrinia plant Patrinia scabiosaefolia Fisch and patrima villosa; Containing effective ingredient such as patrinoside, Hemerocallis citrina Baroni/patrima villosa saponin, loganin, oleanolic acid, inositols; Bitter, pungent, be slightly cold, return lung, large intestine, Liver Channel.Effect is heat-clearing and toxic substances removing, removing blood stasis with potent drugs evacuation of pus; Cure mainly acute appendicitis, lung abscess, dysentery, leukorrhagia, the stagnant stomachache of the stasis of blood in puerperal, pyretic toxicity carbuncle.Modern pharmacology research shows, Herba Patriniae has the effect such as calmness, antibacterial, antiviral, hepatic cholagogic, promotion hematological function.

Cortex Moutan: be the root bark of Paeoniaceae Paeonia plant Paeonia suffruticosa; Containing iridoid glycoside as peoniflorin, oxypaeoniflorin, paeonol, paeonoside etc., also containing effective ingredient such as five galloyl glucoses, gallic acids.Bitter, pungent, be slightly cold, GUIXIN, liver, kidney channel; Effect is clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; Cure mainly the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, WEIJIA, and carbuncle sore tumefacting virus, falls and flutter the pain of injury, beriberoid pyretic arthralgia.Modern pharmacology research shows, Cortex Moutan has CNS inhibition, strengthens the effects such as systema cariovasculare functional, anticoagulation, antiinflammatory, enhancing function of immune system, blood sugar lowering.

The Radix Paeoniae Alba: be the root of Paeoniaceae Paeonia plant peony and Peony; Containing iridoid glycosides as peoniflorin, oxypaeoniflorin, albiflorin, Radix Paeoniae aglycon ketone, galloylpaeoniflorin etc., also containing tannin and volatilization wet goods effective ingredient.Bitter, sour, be slightly cold, return liver, spleen channel; Effect for nourishing blood and seek, relieving spasm to stop pain, yin fluid astringing suppressing the hyperactive liver; Cure mainly blood deficiency cold and heat, epigastric pain, association's pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and has a headache dizzy.Modern pharmacology research shows, the Radix Paeoniae Alba has antiinflammatory, analgesia, enhancing function of immune system, resisting pathogenic microbes, CNS inhibition, anoxia enduring, protect the liver and detoxify, the effect such as antimutagenic and antitumor.

Herba Cistanches: for Herba Orobanches can the fleshy stem of Cistanche Hoffmgg. et Link plants Herba Cistanches and Cistanche Tubulosa; Containing effective ingredient such as boschnaloside, Syring vulgaris phenolic glycoside, echinacosid, imidazolidine compounds, Liriodendrin, daucosterol, betanin, sitosterol, mannitol; Sweet, salty, temperature, returns kidney, large intestine channel.Effect is kidney-replenishing, benefiting essence-blood, intestine moistening road; Cure mainly the sexual impotence of kidney yang deficiency, asthenia of essence and blood, seminal emission, nebulousurine, the frequent micturition heeltap, lumbago flaccidity of the lower limbs, tinnitus order flower, menstruation is spread out the phase, infertility, dryness of the intestine constipation.Modern pharmacology research shows, Herba Cistanches has raising function of immune system, adjustment endocrine, promotes metabolism, improves the effects such as central nervous system function, slow down aging, relieving constipation.

Semen sophorae: also known as the Fructus Sophorae is the fruit of cassia leguminous plant Chinese scholartree; Containing genistein, nimbecetin, sophoricoside, several amino acids and the effective ingredient such as alkaloid, fatty acid; Hardship, cold, return liver, large intestine channel.Effect is cooling blood for hemostasis, liver heat removing and eyesight improving; Cure mainly discharging fresh blood stool, dysentery, metrorrhagia, stranguria with blood, spit blood, epistaxis, dizzy, carbuncle on the back, scalds.Modern pharmacology research shows, the Fructus Sophorae has promotion cardiovascular function, antioxidation, antiinflammatory, Citrin sample, prevents and treats the effects such as osteoporosis.

Radix Salviae Miltiorrhizae: be the root of Lamiaceae Salvia platymiscium Radix Salviae Miltiorrhizae; Containing quinoness such as TANSHINONES, Radix Salviae Miltiorrhizae ketolide, cryptotanshinone, iso tanshinones, also contain water-soluble phenolic compounds as the effective ingredient such as salvianolic acid, protocatechualdehyde.Property bitter, be slightly cold, GUIXIN, Bao Xin, Liver Channel; Effect is blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, and relieving restlessness is calmed the nerves, removing heat from blood eliminating carbuncle; Cure mainly menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, trusted subordinate's pain, WEIJIA is gathered, and pyretic arthralgia swells and ache, traumatic injury, and heat enters nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore.Modern pharmacology research shows, Radix Salviae Miltiorrhizae has enhancing cardio-cerebrovascular function, blood fat reducing and atherosclerosis, anticoagulant and antithrombotic, anoxia enduring, enhancing function of immune system, antiinflammatory and antiallergic, hepatoprotective, anti-gastric-ulcer, improves the effect such as renal function and antioxidation.

Fructus Ligustri Lucidi: be the fruit of Oleaceae Ligustrum plant Fructus Ligustri Lucidi; Containing effective ingredient such as triterpenes, phenolic glycoside class, iridoid glycosides, flavonoid, fatty acid and Fructus Ligustri Lucidi polysaccharide, volatile oil, phospholipids; Sweet, bitter, cool, return liver, kidney channel.Effect is liver and kidney tonifying, clearind deficient heat, improving eyesight; Cure mainly Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision.Modern pharmacology research shows, Fructus Ligustri Lucidi has antiinflammatory, improves immunologic function, suppresses allergy, promotes lipid metabolism, blood sugar lowering, protects the liver, promotes the effects such as hemopoietic system function, antimutagenic and anti-hematoporphyrin derivative (HPD) photooxidation.

The Chinese medicine composition being used for the treatment of diabetes of the present invention, adopt Radix Rehmanniae Preparata, Rhizoma Polygonati, Radix Ophiopogonis, Radix Trichosanthis, Rhizoma Alismatis, Poria, the Rhizoma Anemarrhenae, Rhizoma Dioscoreae, Radix Achyranthis Bidentatae, Cortex Lycii, Cortex Phellodendri, Fructus Corni, Fructus Lycii, Poria, Radix Gentianae, Herba Patriniae, Cortex Moutan, the Radix Paeoniae Alba, Herba Cistanches, Semen sophorae, Radix Salviae Miltiorrhizae, Fructus Ligustri Lucidi is composite, all medicines share, ancestral side's compatibility, there is blood sugar lowering, clearing away liver-fire, removing heat from blood, loosening bowel to relieve constipation, to quench one's thirst effect of the kidney invigorating, for by excessive rising of liver-YANG, the withered constipation in Tianjin caused by insufficiency of kidney-YANG, soreness of the waist and knees, frequency of micturition, the symptom of quenching one's thirst (diabetes) of blood and essence asthenia has significant curative effect, treating both the principal and secondary aspects of a disease, effective percentage reaches more than 90%, for pure Chinese medicinal preparation, cost is low, and toxic and side effects is little.

A kind of oral formulations being used for the treatment of diabetes, raw material primarily of following mass fraction is made: Radix Rehmanniae Preparata 15 ~ 45 parts, Rhizoma Polygonati 25 ~ 75 parts, Radix Ophiopogonis 15 ~ 45 parts, Radix Trichosanthis 20 ~ 60 parts, Rhizoma Alismatis 15 ~ 45 parts, 20 ~ 60 parts, Poria, the Rhizoma Anemarrhenae 15 ~ 45 parts, Rhizoma Dioscoreae 17 ~ 53 parts, Radix Achyranthis Bidentatae 15 ~ 45 parts, Cortex Lycii 15 ~ 45 parts, Cortex Phellodendri 15 ~ 45 parts, Fructus Corni 20 ~ 60 parts, Fructus Lycii 15 ~ 45 parts, 12 ~ 38 parts, Poria, Radix Gentianae 10 ~ 30 parts, Herba Patriniae 15 ~ 45 parts, Cortex Moutan 20 ~ 60 parts, the Radix Paeoniae Alba 15 ~ 45 parts, Herba Cistanches 17 ~ 53 parts, Semen sophorae 15 ~ 45 parts, Radix Salviae Miltiorrhizae 20 ~ 60 parts, Fructus Ligustri Lucidi 15 ~ 45 parts.

Preferably, the described oral formulations being used for the treatment of diabetes, raw material primarily of following mass fraction is made: Radix Rehmanniae Preparata 27 ~ 33 parts, Rhizoma Polygonati 45 ~ 55 parts, Radix Ophiopogonis 27 ~ 33 parts, Radix Trichosanthis 36 ~ 44 parts, Rhizoma Alismatis 27 ~ 33 parts, 36 ~ 44 parts, Poria, the Rhizoma Anemarrhenae 27 ~ 33 parts, Rhizoma Dioscoreae 31 ~ 39 parts, Radix Achyranthis Bidentatae 27 ~ 33 parts, Cortex Lycii 27 ~ 33 parts, Cortex Phellodendri 27 ~ 33 parts, Fructus Corni 36 ~ 44 parts, Fructus Lycii 27 ~ 33 parts, 22 ~ 28 parts, Poria, Radix Gentianae 18 ~ 22 parts, Herba Patriniae 27 ~ 33 parts, Cortex Moutan 36 ~ 44 parts, the Radix Paeoniae Alba 27 ~ 33 parts, Herba Cistanches 31 ~ 39 parts, Semen sophorae 27 ~ 33 parts, Radix Salviae Miltiorrhizae 36 ~ 44 parts, Fructus Ligustri Lucidi 27 ~ 33 parts.

Preferred further, the described oral formulations being used for the treatment of diabetes, the raw material primarily of following mass fraction is made: Radix Rehmanniae Preparata 30 parts, Rhizoma Polygonati 50 parts, Radix Ophiopogonis 30 parts, Radix Trichosanthis 40 parts, Rhizoma Alismatis 30 parts, 40 parts, Poria, the Rhizoma Anemarrhenae 30 parts, Rhizoma Dioscoreae 35 parts, Radix Achyranthis Bidentatae 30 parts, Cortex Lycii 30 parts, Cortex Phellodendri 30 parts, Fructus Corni 40 parts, Fructus Lycii 30 parts, 25 parts, Poria, Radix Gentianae 20 parts, Herba Patriniae 30 parts, Cortex Moutan 40 parts, the Radix Paeoniae Alba 30 parts, Herba Cistanches 35 parts, Semen sophorae 30 parts, Radix Salviae Miltiorrhizae 40 parts, Fructus Ligustri Lucidi 30 parts.

Described oral formulations is acceptable powder, decoction, pill, capsule or oral liquid on Chinese medicine and pharmacy.

The preparation method of described powder is: after raw material pulverizing, mixes and get final product by formula ratio.Gained powder is incapsulated in shell, obtains capsule.The consumption of described powder or capsule is: everyone each 6 ~ 12g, 3 times on the one.

The consumption of described oral liquid is: everyone each 10 ~ 20ml, 3 times on the one.The consumption of described pill is: everyone each 10 ~ 20g, 3 times on the one.

Preferably, described oral formulations is decoction.

The above-mentioned preparation method being used for the treatment of the oral formulations of diabetes, after comprising the crude drug mixing of getting formula ratio, adds the soak by water 30 ~ 50min of crude drug 3 ~ 5 times of quality for the first time, obtains decocting liquid and medicinal residues; Second time adds the soak by water 30 ~ 50min of crude drug 2 ~ 3 times of quality, obtains decocting liquid and medicinal residues; Merge twice decocting liquid, obtain decoction.

In above-mentioned preparation method, decoction container is based on fire-resistant marmite or ceramic pan, and copper pot or enamel pan also can be used.Before first time decocts, first cold water (room temperature) soaks, and soak time is 20 ~ 40min.During decoction however time stir, note the duration and degree of heating, prevent medicine coking or the intensity of a fire from too quicklyly making liquid medicine spill, decoct dry.

The consumption of described decoction is: everyone each 200 ~ 300ml, 2 times on the one.

The oral formulations being used for the treatment of diabetes of the present invention, primarily of Radix Rehmanniae Preparata, Rhizoma Polygonati, Radix Ophiopogonis, Radix Trichosanthis, Rhizoma Alismatis, Poria, the Rhizoma Anemarrhenae, Rhizoma Dioscoreae, Radix Achyranthis Bidentatae, Cortex Lycii, Cortex Phellodendri, Fructus Corni, Fructus Lycii, Poria, Radix Gentianae, Herba Patriniae, Cortex Moutan, the Radix Paeoniae Alba, Herba Cistanches, Semen sophorae, Radix Salviae Miltiorrhizae, Fructus Ligustri Lucidi is composite makes, there is blood sugar lowering, clearing away liver-fire, removing heat from blood, loosening bowel to relieve constipation, the effect of the kidney invigorating of quenching one's thirst; Make oral formulations to use, good patient compliance, bioavailability is high, instant effect; For by excessive rising of liver-YANG, the withered constipation in the Tianjin caused by insufficiency of kidney-YANG, soreness of the waist and knees, frequency of micturition, the symptom of quenching one's thirst (diabetes) of blood and essence asthenia has significant curative effect, treating both the principal and secondary aspects of a disease; For pure Chinese medicinal preparation, cost is low, and toxic and side effects is little.

Detailed description of the invention

Below in conjunction with detailed description of the invention, the present invention is further illustrated.

Embodiment 1

The Chinese medicine composition being used for the treatment of diabetes of the present embodiment, is made up of the component of following mass fraction: Radix Rehmanniae Preparata 30 parts, Rhizoma Polygonati 50 parts, Radix Ophiopogonis 30 parts, Radix Trichosanthis 40 parts, Rhizoma Alismatis 30 parts, 40 parts, Poria, the Rhizoma Anemarrhenae 30 parts, Rhizoma Dioscoreae 35 parts, Radix Achyranthis Bidentatae 30 parts, Cortex Lycii 30 parts, Cortex Phellodendri 30 parts, Fructus Corni 40 parts, Fructus Lycii 30 parts, 25 parts, Poria, Radix Gentianae 20 parts, Herba Patriniae 30 parts, Cortex Moutan 40 parts, the Radix Paeoniae Alba 30 parts, Herba Cistanches 35 parts, Semen sophorae 30 parts, Radix Salviae Miltiorrhizae 40 parts, Fructus Ligustri Lucidi 30 parts.

The oral formulations being used for the treatment of diabetes of the present embodiment is decoction, and the crude drug primarily of following mass fraction is made: Radix Rehmanniae Preparata 30 parts, Rhizoma Polygonati 50 parts, Radix Ophiopogonis 30 parts, Radix Trichosanthis 40 parts, Rhizoma Alismatis 30 parts, 40 parts, Poria, the Rhizoma Anemarrhenae 30 parts, Rhizoma Dioscoreae 35 parts, Radix Achyranthis Bidentatae 30 parts, Cortex Lycii 30 parts, Cortex Phellodendri 30 parts, Fructus Corni 40 parts, Fructus Lycii 30 parts, 25 parts, Poria, Radix Gentianae 20 parts, Herba Patriniae 30 parts, Cortex Moutan 40 parts, the Radix Paeoniae Alba 30 parts, Herba Cistanches 35 parts, Semen sophorae 30 parts, Radix Salviae Miltiorrhizae 40 parts, Fructus Ligustri Lucidi 30 parts.

The preparation method of described decoction is: after getting the crude drug mixing of formula ratio, add the water of crude drug 4 times of quality for the first time, decoct 40min, obtain decocting liquid and medicinal residues after soaking 30min; Second time adds the soak by water 30min of crude drug 3 times of quality, obtains decocting liquid and medicinal residues; Merge twice decocting liquid, obtain decoction.

The using method of the present embodiment gained decoction is: oral, everyone each 200 ~ 300ml, 2 times on the one.

Embodiment 2

The Chinese medicine composition being used for the treatment of diabetes of the present embodiment, is made up of the component of following mass fraction: Radix Rehmanniae Preparata 45 parts, Rhizoma Polygonati 25 parts, Radix Ophiopogonis 45 parts, Radix Trichosanthis 60 parts, Rhizoma Alismatis 15 parts, 20 parts, Poria, the Rhizoma Anemarrhenae 45 parts, Rhizoma Dioscoreae 17 parts, Radix Achyranthis Bidentatae 45 parts, Cortex Lycii 15 parts, Cortex Phellodendri 45 parts, Fructus Corni 20 parts, Fructus Lycii 45 parts, 12 parts, Poria, Radix Gentianae 30 parts, Herba Patriniae 15 parts, Cortex Moutan 20 parts, the Radix Paeoniae Alba 45 parts, Herba Cistanches 53 parts, Semen sophorae 15 parts, Radix Salviae Miltiorrhizae 20 parts, Fructus Ligustri Lucidi 45 parts.

The oral formulations being used for the treatment of diabetes of the present embodiment is decoction, and the crude drug primarily of following mass fraction is made: Radix Rehmanniae Preparata 45 parts, Rhizoma Polygonati 25 parts, Radix Ophiopogonis 45 parts, Radix Trichosanthis 60 parts, Rhizoma Alismatis 15 parts, 20 parts, Poria, the Rhizoma Anemarrhenae 45 parts, Rhizoma Dioscoreae 17 parts, Radix Achyranthis Bidentatae 45 parts, Cortex Lycii 15 parts, Cortex Phellodendri 45 parts, Fructus Corni 20 parts, Fructus Lycii 45 parts, 12 parts, Poria, Radix Gentianae 30 parts, Herba Patriniae 15 parts, Cortex Moutan 20 parts, the Radix Paeoniae Alba 45 parts, Herba Cistanches 53 parts, Semen sophorae 15 parts, Radix Salviae Miltiorrhizae 20 parts, Fructus Ligustri Lucidi 45 parts.

The preparation method of described decoction is: after getting the crude drug mixing of formula ratio, add the water of crude drug 5 times of quality for the first time, decoct 50min, obtain decocting liquid and medicinal residues after soaking 40min; Second time adds the soak by water 50min of crude drug 3 times of quality, obtains decocting liquid and medicinal residues; Merge twice decocting liquid, obtain decoction.

The using method of the present embodiment gained decoction is: oral, everyone each 200 ~ 300ml, 2 times on the one.

Embodiment 3

The Chinese medicine composition being used for the treatment of diabetes of the present embodiment, is made up of the component of following mass fraction: Radix Rehmanniae Preparata 15 parts, Rhizoma Polygonati 75 parts, Radix Ophiopogonis 15 parts, Radix Trichosanthis 20 parts, Rhizoma Alismatis 45 parts, 60 parts, Poria, the Rhizoma Anemarrhenae 15 parts, Rhizoma Dioscoreae 53 parts, Radix Achyranthis Bidentatae 15 parts, Cortex Lycii 45 parts, Cortex Phellodendri 15 parts, Fructus Corni 60 parts, Fructus Lycii 15 parts, 38 parts, Poria, Radix Gentianae 10 parts, Herba Patriniae 45 parts, Cortex Moutan 60 parts, the Radix Paeoniae Alba 15 parts, Herba Cistanches 17 parts, Semen sophorae 45 parts, Radix Salviae Miltiorrhizae 60 parts, Fructus Ligustri Lucidi 15 parts.

The oral formulations being used for the treatment of diabetes of the present embodiment is decoction, and the crude drug primarily of following mass fraction is made: Radix Rehmanniae Preparata 15 parts, Rhizoma Polygonati 75 parts, Radix Ophiopogonis 15 parts, Radix Trichosanthis 20 parts, Rhizoma Alismatis 45 parts, 60 parts, Poria, the Rhizoma Anemarrhenae 15 parts, Rhizoma Dioscoreae 53 parts, Radix Achyranthis Bidentatae 15 parts, Cortex Lycii 45 parts, Cortex Phellodendri 15 parts, Fructus Corni 60 parts, Fructus Lycii 15 parts, 38 parts, Poria, Radix Gentianae 10 parts, Herba Patriniae 45 parts, Cortex Moutan 60 parts, the Radix Paeoniae Alba 15 parts, Herba Cistanches 17 parts, Semen sophorae 45 parts, Radix Salviae Miltiorrhizae 60 parts, Fructus Ligustri Lucidi 15 parts.

The preparation method of described decoction is: after getting the crude drug mixing of formula ratio, add the water of crude drug 3 times of quality for the first time, decoct 30min, obtain decocting liquid and medicinal residues after soaking 20min; Second time adds the soak by water 30min of crude drug 2 times of quality, obtains decocting liquid and medicinal residues; Merge twice decocting liquid, obtain decoction.

The using method of the present embodiment gained decoction is: oral, everyone each 200 ~ 300ml, 2 times on the one.

Embodiment 4

The Chinese medicine composition being used for the treatment of diabetes of the present embodiment, is made up of the component of following mass fraction: Radix Rehmanniae Preparata 27 parts, Rhizoma Polygonati 55 parts, Radix Ophiopogonis 33 parts, Radix Trichosanthis 36 parts, Rhizoma Alismatis 33 parts, 36 parts, Poria, the Rhizoma Anemarrhenae 27 parts, Rhizoma Dioscoreae 39 parts, Radix Achyranthis Bidentatae 27 parts, Cortex Lycii 33 parts, Cortex Phellodendri 27 parts, Fructus Corni 44 parts, Fructus Lycii 27 parts, 28 parts, Poria, Radix Gentianae 18 parts, Herba Patriniae 33 parts, Cortex Moutan 36 parts, the Radix Paeoniae Alba 33 parts, Herba Cistanches 31 parts, Semen sophorae 33 parts, Radix Salviae Miltiorrhizae 36 parts, Fructus Ligustri Lucidi 33 parts.

The oral formulations being used for the treatment of diabetes of the present embodiment is powder, is prepared by above-mentioned Chinese medicine composition.Preparation method is: after raw material pulverizing, mixes and obtain powder by formula ratio.Gained powder is incapsulated in shell, obtains capsule.

The instructions of taking of the oral formulations of the present embodiment is: everyone each 6 ~ 12g, three times on the one.

Embodiment 5

The Chinese medicine composition being used for the treatment of diabetes of the present embodiment, is made up of the component of following mass fraction: Radix Rehmanniae Preparata 33 parts, Rhizoma Polygonati 45 parts, Radix Ophiopogonis 27 parts, Radix Trichosanthis 44 parts, Rhizoma Alismatis 27 parts, 44 parts, Poria, the Rhizoma Anemarrhenae 33 parts, Rhizoma Dioscoreae 31 parts, Radix Achyranthis Bidentatae 33 parts, Cortex Lycii 27 parts, Cortex Phellodendri 33 parts, Fructus Corni 36 parts, Fructus Lycii 33 parts, 22 parts, Poria, Radix Gentianae 22 parts, Herba Patriniae 27 parts, Cortex Moutan 44 parts, the Radix Paeoniae Alba 27 parts, Herba Cistanches 39 parts, Semen sophorae 27 parts, Radix Salviae Miltiorrhizae 44 parts, Fructus Ligustri Lucidi 27 parts.

The oral formulations being used for the treatment of diabetes of the present embodiment is powder, is prepared by above-mentioned Chinese medicine composition.Preparation method is: after raw material pulverizing, mixes and obtain powder by formula ratio.Gained powder is incapsulated in shell, obtains capsule.

The instructions of taking of the oral formulations of the present embodiment is: everyone each 6 ~ 12g, three times on the one.

Model case

Model case 1: Zhu, man, 40 years old, Pekinese, private prosecution suffered from diabetes 6 years, takes the recovery from illness in three months of embodiment 1 gained decoction, without recurrence.

Model case 2: Ma, man, 55 years old, Pekinese, private prosecution suffered from diabetes 15 years, and take embodiment 2 gained decoction and eliminate complications in three months, recovery from illness in five months, without recurrence.

Model case 3: flood certain, man, 34 years old, people from Zhengzhou, diabetes 5 years were suffered from private prosecution, take the recovery from illness in three months of embodiment 3 gained decoction, without recurrence.

Claims (6)

1. one kind is used for the treatment of the Chinese medicine composition of diabetes, it is characterized in that: be made up of the component of following mass fraction: Radix Rehmanniae Preparata 15 ~ 45 parts, Rhizoma Polygonati 25 ~ 75 parts, Radix Ophiopogonis 15 ~ 45 parts, Radix Trichosanthis 20 ~ 60 parts, Rhizoma Alismatis 15 ~ 45 parts, 20 ~ 60 parts, Poria, the Rhizoma Anemarrhenae 15 ~ 45 parts, Rhizoma Dioscoreae 17 ~ 53 parts, Radix Achyranthis Bidentatae 15 ~ 45 parts, Cortex Lycii 15 ~ 45 parts, Cortex Phellodendri 15 ~ 45 parts, Fructus Corni 20 ~ 60 parts, Fructus Lycii 15 ~ 45 parts, 12 ~ 38 parts, Poria, Radix Gentianae 10 ~ 30 parts, Herba Patriniae 15 ~ 45 parts, Cortex Moutan 20 ~ 60 parts, the Radix Paeoniae Alba 15 ~ 45 parts, Herba Cistanches 17 ~ 53 parts, Semen sophorae 15 ~ 45 parts, Radix Salviae Miltiorrhizae 20 ~ 60 parts, Fructus Ligustri Lucidi 15 ~ 45 parts.

2. the Chinese medicine composition being used for the treatment of diabetes according to claim 1, is characterized in that: be made up of the component of following mass fraction: Radix Rehmanniae Preparata 30 parts, Rhizoma Polygonati 50 parts, Radix Ophiopogonis 30 parts, Radix Trichosanthis 40 parts, Rhizoma Alismatis 30 parts, 40 parts, Poria, the Rhizoma Anemarrhenae 30 parts, Rhizoma Dioscoreae 35 parts, Radix Achyranthis Bidentatae 30 parts, Cortex Lycii 30 parts, Cortex Phellodendri 30 parts, Fructus Corni 40 parts, Fructus Lycii 30 parts, 25 parts, Poria, Radix Gentianae 20 parts, Herba Patriniae 30 parts, Cortex Moutan 40 parts, the Radix Paeoniae Alba 30 parts, Herba Cistanches 35 parts, Semen sophorae 30 parts, Radix Salviae Miltiorrhizae 40 parts, Fructus Ligustri Lucidi 30 parts.

3. one kind is used for the treatment of the oral formulations of diabetes, it is characterized in that: the raw material primarily of following mass fraction is made: Radix Rehmanniae Preparata 15 ~ 45 parts, Rhizoma Polygonati 25 ~ 75 parts, Radix Ophiopogonis 15 ~ 45 parts, Radix Trichosanthis 20 ~ 60 parts, Rhizoma Alismatis 15 ~ 45 parts, 20 ~ 60 parts, Poria, the Rhizoma Anemarrhenae 15 ~ 45 parts, Rhizoma Dioscoreae 17 ~ 53 parts, Radix Achyranthis Bidentatae 15 ~ 45 parts, Cortex Lycii 15 ~ 45 parts, Cortex Phellodendri 15 ~ 45 parts, Fructus Corni 20 ~ 60 parts, Fructus Lycii 15 ~ 45 parts, 12 ~ 38 parts, Poria, Radix Gentianae 10 ~ 30 parts, Herba Patriniae 15 ~ 45 parts, Cortex Moutan 20 ~ 60 parts, the Radix Paeoniae Alba 15 ~ 45 parts, Herba Cistanches 17 ~ 53 parts, Semen sophorae 15 ~ 45 parts, Radix Salviae Miltiorrhizae 20 ~ 60 parts, Fructus Ligustri Lucidi 15 ~ 45 parts.

4. the oral formulations being used for the treatment of diabetes according to claim 3, is characterized in that: the raw material primarily of following mass fraction is made: Radix Rehmanniae Preparata 30 parts, Rhizoma Polygonati 50 parts, Radix Ophiopogonis 30 parts, Radix Trichosanthis 40 parts, Rhizoma Alismatis 30 parts, 40 parts, Poria, the Rhizoma Anemarrhenae 30 parts, Rhizoma Dioscoreae 35 parts, Radix Achyranthis Bidentatae 30 parts, Cortex Lycii 30 parts, Cortex Phellodendri 30 parts, Fructus Corni 40 parts, Fructus Lycii 30 parts, 25 parts, Poria, Radix Gentianae 20 parts, Herba Patriniae 30 parts, Cortex Moutan 40 parts, the Radix Paeoniae Alba 30 parts, Herba Cistanches 35 parts, Semen sophorae 30 parts, Radix Salviae Miltiorrhizae 40 parts, Fructus Ligustri Lucidi 30 parts.

5. the oral formulations being used for the treatment of diabetes according to claim 3 or 4, is characterized in that: described oral formulations is powder, decoction, pill, capsule or oral liquid.

6. be used for the treatment of a preparation method for the oral formulations of diabetes as claimed in claim 3, it is characterized in that: after comprising the crude drug mixing of getting formula ratio, add the soak by water 30 ~ 50min of crude drug 3 ~ 5 times of quality for the first time, obtain decocting liquid and medicinal residues; Second time adds the soak by water 30 ~ 50min of crude drug 2 ~ 3 times of quality, obtains decocting liquid and medicinal residues; Merge twice decocting liquid, obtain decoction.