CN114146113A

CN114146113A - Kidney-tonifying traditional Chinese medicine composition and preparation method thereof

Info

Publication number: CN114146113A
Application number: CN202111589900.0A
Authority: CN
Inventors: 陈小宝
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-12-23
Filing date: 2021-12-23
Publication date: 2022-03-08

Abstract

The invention relates to the technical field of traditional Chinese medicine compositions, and particularly relates to a kidney-tonifying traditional Chinese medicine composition and a preparation method thereof, wherein the kidney-tonifying traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10-20 parts of ginseng, 5-15 parts of gecko, 5-20 parts of penis cervi, 10-15 parts of penis cervi, 5-15 parts of cordyceps sinensis, 8-20 parts of pilose antler, 1-15 parts of hippocampus, 1-15 parts of syngnathus, 15-25 parts of dogwood, 10-15 parts of schisandra chinensis, 10-20 parts of dipsacus asperoides, 5-15 parts of eucommia ulmoides, 15-20 parts of tortoise plastron, 15-20 parts of turtle shell, 12-15 parts of cynomorium songaricum, 12-15 parts of epimedium herb and 5-15 parts of keel. The preparation method comprises the following steps: making the raw materials into medicinal powder, mixing Oryza Glutinosa powder with water, decocting with strong fire for 5-10min, adding the medicinal powder, and making into pill. The Chinese medicinal composition has effects of nourishing five internal organs, invigorating primordial qi, dredging nine orifices, promoting blood circulation and promoting blood circulation.

Description

Kidney-tonifying traditional Chinese medicine composition and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for tonifying kidney and a preparation method thereof.

Background

Traditional Chinese medicine considers kidney as the congenital foundation. When kidney essence is abundant, people can normally develop and reproduce, if men are kidney deficiency, impotence and spermatorrhea are easy to occur, and women are easy to have diseases such as infertility and amenorrhea due to kidney deficiency; if kidney deficiency is caused by kidney deficiency of old people, kidney deficiency of young people, and fatigue transition, soreness and pain of waist and knees, slow reaction and slow movement will be caused.

At present, the treatment for the deficiency of the kidney mostly adopts medicine tonifying and food tonifying, and the treatment prescription and the food tonifying prescription are also diversified, but the existing kidney tonifying prescription has poor treatment effect and single function.

Disclosure of Invention

The invention aims to provide a traditional Chinese medicine composition for tonifying the kidney, which has the effects of tonifying five internal organs, invigorating primordial qi, dredging nine orifices, promoting blood circulation and invigorating blood circulation.

The invention also aims to provide a preparation method of the kidney-tonifying traditional Chinese medicine composition, which is to mix the medicinal powder with the glutinous rice flour to prepare pills which are convenient to take.

The technical problem to be solved by the invention is realized by adopting the following technical scheme.

On one hand, the embodiment of the invention provides a kidney-tonifying traditional Chinese medicine composition which comprises the following raw materials in parts by weight:

10-20 parts of ginseng, 5-15 parts of gecko, 5-20 parts of penis cervi, 10-15 parts of penis cervi, 5-15 parts of cordyceps sinensis, 8-20 parts of pilose antler, 1-15 parts of hippocampus, 1-15 parts of syngnathus, 15-25 parts of dogwood, 10-15 parts of schisandra chinensis, 10-20 parts of dipsacus asperoides, 5-15 parts of eucommia ulmoides, 15-20 parts of tortoise plastron, 15-20 parts of turtle shell, 12-15 parts of cynomorium songaricum, 12-15 parts of epimedium herb and 5-15 parts of keel.

On the other hand, the embodiment of the invention provides a preparation method of a traditional Chinese medicine composition for tonifying the kidney, which comprises the following steps of preparing raw materials into medicinal powder, mixing glutinous rice flour with water, decocting with strong fire for 5-10min, adding the medicinal powder, and preparing pills.

Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:

in the invention, the traditional Chinese medicine composition prepared by compatibility of traditional Chinese medicines such as ginseng, gecko, penis cervi and the like has the effects of tonifying five internal organs, invigorating primordial qi, dredging nine orifices, promoting blood circulation and activating blood and generating blood, can be used for treating symptoms such as impotence and premature ejaculation, infertility, spermatorrhea, frequent micturition and urgent micturition caused by kidney deficiency, and can also be used for treating symptoms such as femoral head necrosis, osteoporosis and the like.

In the invention, the traditional Chinese medicine composition is prepared into pills which are convenient to eat. In the preparation process, the traditional Chinese medicinal materials are directly prepared into powder and then mixed with the glutinous rice flour, so that the effective ingredients in the traditional Chinese medicinal materials can be utilized to the maximum extent; glutinous rice flour is used as excipient, which does not affect the efficacy of each Chinese medicinal material.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.

It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.

Ginseng radix has effects of invigorating primordial qi, invigorating spleen, benefiting lung, promoting fluid production, quenching thirst, tranquilizing mind, and improving intelligence, and can be used for treating diseases such as primordial qi collapse, pale complexion, cardiopalmus, restlessness, and hidrosis; can also be used for treating spleen and lung qi deficiency, such as weakness of spleen and stomach, anorexia, loose stool, asthenia, emesis, diarrhea, pale tongue, slow pulse, cough, asthma, asthenia, spontaneous perspiration, weak pulse, and susceptibility to wind-cold; it can also be used for treating thirst due to body fluid consumption, qi and yin deficiency due to heat, fever, polydipsia, sweating, fatigue, large and weak pulse, polydipsia, rapid and weak pulse, and qi and yin deficiency due to internal heat. In addition, it can be used for treating blood deficiency, impotence and preponderance of healthy qi.

Gecko contains 18 kinds of amino acids such as aspartic acid, threonine, histidine, methionine, tryptophan, etc., phospholipids such as lysophosphatidylcholine, sphingomyelin, phosphatidylcholine, etc., various fatty acids, various inorganic elements such as barium, phosphorus, magnesium, etc., carnosine, choline, carnitine, guanine, protein, fat, etc. Has effects in invigorating lung and kidney, promoting inspiration, relieving asthma, and promoting blood circulation.

In the invention, the penis cervi is plum blossom penis. The surface is brownish yellow to dark brown, smooth and translucent, and the diagonal ribs can be seen. Sweet, salty and warm in nature. Has effects in tonifying kidney essence, invigorating kidney yang, replenishing essence, and strengthening waist and knee joint. Can be used for treating kidney deficiency, strain, soreness of waist and knees, deafness, tinnitus, sexual impotence, spermatorrhea, premature ejaculation, infertility due to cold womb, and clear and thin leukorrhagia.

In the invention, the deer kidney is kidney of sika deer, and the preparation method comprises the following steps: cleaning penis et testis Cervi, soaking in warm water, slicing, sun drying or oven drying, adding penis et testis Cervi into parched hot sand, parching to loose, and grinding into powder. Can be used for treating sexual impotence, tinnitus due to kidney deficiency, and cold womb.

Cordyceps sinensis (berk.) Sacc. Is a complex of stroma of Cordyceps sinensis (L.) Link parasitizing on larva of insect of Hepialidae and larva of insect of Hepialidae. Has effects of invigorating kidney, benefiting lung, stopping bleeding, and eliminating phlegm. Can be used for treating sexual impotence, spermatorrhea, soreness of waist and knees, cough, asthma, and phlegm blood.

Cornu Cervi Pantotrichum refers to young horn of male deer of Cervus Nippon Temminck or Cervus Elaphus L which is not ossified and has cornu Cervi Pantotrichum. The cornu Cervi Pantotrichum contains phospholipid, glycolipid, gum lipid, hormone, fatty acid, amino acid, protein, and calcium, phosphorus, magnesium, and sodium, wherein the amino acid content is more than 50%. Cornu Cervi Pantotrichum has effects of invigorating kidney, supporting yang, promoting vital essence generation, replenishing blood, nourishing marrow, and strengthening bone.

The hippocampus contains androgenic hormone, has the effects of tonifying kidney and strengthening yang, can reduce the activity of monoamine oxidase in a human body, and has the effect of resisting aging; the water extract of Hippocampus has effects of promoting transformation of human lymphocyte, inhibiting growth and reproduction of cancer cell, and resisting cancer.

The Syngnathus is prepared from Syngnathus cuneatus, Syngnathus niponicas or Syngnathus acus of Syngnathidae by removing involucra and viscera. Has effects in invigorating kidney and supporting yang. Can be used for treating sexual impotence and infertility. Has exciting effect, and can be used for the aged and the people who are in debilitation.

Dogwood has the effects of tonifying liver and kidney, astringing and relieving depletion. It is commonly used for vertigo, tinnitus, soreness and pain of waist and knees, impotence, spermatorrhea, enuresis, frequent micturition, metrorrhagia, leukorrhagia, profuse sweating, exhaustion, internal heat, and diabetes.

The schisandra chinensis has the effects of astringing lung, nourishing kidney, promoting fluid production, absorbing sweat and controlling nocturnal emission. It is used to treat lung deficiency, asthma, cough, dry mouth, thirst, spontaneous perspiration, night sweat, fatigue, emaciation, nocturnal emission, chronic diarrhea, and chronic dysentery.

Chuan xu Duan, slightly warm, bitter and pungent in flavor. It enters liver and kidney meridians. Has effects in nourishing liver and kidney, strengthening muscle and bone, promoting fracture, and preventing metrorrhagia.

Eucommia ulmoides contains pinoresinol diglucoside, D-eugenol, eucommia ulmoides glycosides, eucommia ulmoides extract A, erythro-dihydroxy dehydro-dibastinol and other components. Warm in nature and sweet in taste. It enters liver and kidney meridians. Has effects in nourishing liver and kidney, strengthening muscle and bone, and preventing miscarriage. It also has effects in lowering blood pressure, enhancing immunity, promoting urination, relieving pain, and relieving inflammation.

Tortoise plastron contains cholesterol and ossein, and hydrolysate contains various amino acids, fat, protein and calcium salt. Slightly cold in nature, salty and sweet in flavor. Enters liver channel, kidney channel and heart channel, and has the effects of nourishing yin, suppressing yang, invigorating kidney, strengthening bone, nourishing blood and tonifying heart.

Carapax Trionycis contains animal glue, keratin, ossein, vitamin D, essential amino acids, calcium carbonate, and calcium phosphate, has slightly cold nature and salty taste, and has effects of replenishing blood, resisting hepatic fibrosis, resisting cancer, and enhancing immunity.

Herba Cynomorii containing tannin, triterpenoid saponin, acetylursolic acid, herba Cynomorii terpene, daucosterol, (+) -catechin, 2, 6-diethyl-3-methylpyrazine, 3-sitosterol oleate, etc. Has effects of invigorating kidney yang, replenishing essence and blood, and loosening bowel to relieve constipation. It is indicated for atrophy-flaccidity of waist and knees, impotence, spermatorrhea, constipation due to intestinal dryness.

Xian Ling Pi is pungent and sweet in flavor and warm in nature. It enters liver and kidney meridians. Has the functions of invigorating kidney yang, strengthening bones and muscles and dispelling wind-damp. It is combined with deer kidney and ginseng to treat kidney deficiency, soreness and pain of waist and legs, cold and damp scrotum, asthenia, listlessness and poor appetite.

The Os Draconis is skeleton fossil of ancient mammal elephant, rhinoceros, three-toe horse, cattle, deer, etc., or fossil of elephant incisors. Consists of apatite, calcite and a small amount of clay mineral. Has effects of tranquilizing mind, suppressing hyperactive liver, subsiding yang, inducing astringency, and astringing.

In some embodiments of the invention, the traditional Chinese medicine composition further comprises, by weight, 1-15 parts of calcined oyster, 15-20 parts of radix asparagi, 5-15 parts of prepared rehmannia root, 10-15 parts of angelica sinensis, 1-20 parts of poria cocos, 1-20 parts of astragalus membranaceus, 5-25 parts of medlar, 10-15 parts of cherokee rose fruit and 10-15 parts of fructus alpiniae oxyphyllae.

The Concha Ostreae preparata is shell of Ostreidae. The main functional indications are as follows: astringe yin, subdue yang, check sweating, astringe essence, resolve phlegm and soften hard masses. Can be used for treating epilepsy, vertigo, spontaneous perspiration, night sweat, spermatorrhea, stranguria with turbid urine, metrorrhagia, leukorrhagia, scrofula, goiter, palpitation, insomnia, vertigo, tinnitus, scrofula, subcutaneous nodule, lump in abdomen, spontaneous perspiration, night sweat, spermatorrhea, metrorrhagia, gastralgia, and pantothenic acid.

The radix asparagi has the effects of nourishing yin, moistening dryness, clearing lung and promoting fluid production. Can be used for treating dry cough due to lung dryness, cough with sticky phlegm, dry throat, thirst, and constipation due to intestinal dryness.

Prepared rehmannia root, radix rehmanniae Praeparata, with mild nature and sweet taste, has the effects of enriching blood, nourishing yin, replenishing vital essence and replenishing marrow. And in combination with tortoise shell, cynomorium songaricum, achyranthes bidentata and the like, the traditional Chinese medicine composition can tonify kidney, replenish essence, strengthen tendons and bones, and treat impotence and weakness of waist and knees and weakness of muscles and bones caused by deficiency of kidney essence.

Dang Gui is warm in nature, sweet and pungent in flavor. Has effects in replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, constipation due to intestinal dryness, rheumatalgia, traumatic injury, superficial infection, pyocutaneous disease, etc.

Poria contains polysaccharide, triterpene, gum, protein, fatty acid, ergosterol, choline, adenine, lecithin, histadine pachyman lyase, protease, and inorganic elements such as calcium, magnesium, phosphorus, iron, sodium, potassium, and manganese. Mild in nature, sweet and bland in flavor. It enters heart and spleen meridians. Has effects of calming heart, tranquilizing mind, and inducing diuresis, and can be used for treating symptoms such as restlessness, amnesia, heart deficiency, blood deficiency, absentmindedness, and insomnia.

Radix astragali is the dried root of Astragalus membranaceus bge of Leguminosae. Has effects in invigorating qi, consolidating superficial resistance, expelling toxic materials, expelling pus, promoting urination, and promoting granulation. Can be used for treating deficiency of vital energy, asthenia, chronic diarrhea, proctoptosis, spontaneous perspiration, edema, uterine prolapse, albuminuria due to chronic nephritis, diabetes, and unhealed wound.

The medlar contains polysaccharide, fatty acid, betaine, carotene, riboflavin, nicotinic acid, amino acid, vitamin C and a plurality of trace elements, and also contains atropine, daucosterol, cryptoxanthin, zeaxanthin, scopoletin and other components. Mild in nature and sweet in taste. It enters liver and kidney meridians. Has effects of nourishing liver and kidney, replenishing vital essence, and improving eyesight.

Fructus Rosae Laevigatae contains triterpenes, saponin, citric acid, agrimonine, tormentic acid-6-methoxy-beta-D-glucopyranose ester, ursolic acid, fructus Rosae Laevigatae tannin A, etc. Mild in nature, sour, sweet and astringent in taste. It enters kidney, bladder and large intestine meridians. Has effects in stopping nocturnal emission, reducing urination, astringing intestine, and relieving diarrhea. It can be used for treating spermatorrhea, enuresis, frequent micturition, leukorrhagia, chronic diarrhea, and chronic dysentery.

Fructus Alpinae Oxyphyllae contains volatile oil, cardiotonic component fructus Alpiniae Oxyphyllae ketone A, irritant component fructus Alpiniae Oxyphyllae ketone B, calcium antagonist fructus Alpiniae Oxyphyllae alcohol, antiulcer component fructus Alpiniae Oxyphyllae ketone, zingiberene, zingiberol, and myrcene. Warm in nature and pungent in flavor. It enters spleen and kidney meridians. Warming spleen to stop diarrhea, controlling saliva, warming kidney, securing essence and reducing urination.

In some embodiments of the invention, the traditional Chinese medicine composition further comprises 5-20 parts of rhizoma polygonati, 12-18 parts of bighead atractylodes rhizome, 15-18 parts of white peony root, 15-20 parts of selfheal, 10-20 parts of ligusticum wallichii, 5-15 parts of radix achyranthis bidentatae, 1-15 parts of longan, 1-15 parts of jujube kernel, 12-18 parts of flatstem milkvetch seed and 12-15 parts of semen cuscutae.

Rhizoma Polygonati containing steroidal saponin components such as diosgenin, digitonin, sarsasapogenin, etc.; the flavone component comprises apigenin. In addition, contains azetidine carboxylic acid, aspartic acid, homoserine vitexin xyloside, isoliquiritigenin glass, syringaresinol, 14 alpha-hydroxyl Siberian knotweed glycoside A, polygonatum kingianum glycoside A and the like. Sweet in flavor and neutral in nature. It enters spleen, lung and kidney meridians. Has effects in invigorating qi, nourishing yin, invigorating spleen, moistening lung, and invigorating kidney.

Rhizoma Atractylodis Macrocephalae the tuber and rhizoma Atractylodis Macrocephalae the tuber contain volatile oil, and the main components of the oil are atractylone, atractylol, atractylenolide, etc. Has the functions of invigorating spleen and stomach, eliminating dampness and promoting diuresis, stopping sweating and preventing miscarriage, etc. Can be used for treating spleen deficiency, anorexia, dyspepsia, diarrhea, edema, spontaneous perspiration, and threatened abortion. It can be used for treating ascites due to hepatic cirrhosis, primary liver cancer, Meniere's syndrome, chronic lumbago, acute enteritis, and leukopenia.

Radix Paeoniae alba is dried root of Paeonia lactiflora pall of Ranunculaceae. Paeoniflorin, hydroxy paeoniflorin, benzoylpaeoniflorin, albiflorin, oxypaeoniflorin, paeoniflorin, hederagenin, paeoniflorin ketone, galloyl paeoniflorin, kaempferol-3, 7-di-O-beta-D-glucoside, daucostin, beta-sitosterol, paeoniflorin and the like, wherein the volatile oil mainly contains benzoic acid, paeonol and the like. Has the functions of nourishing blood, regulating menstruation, astringing yin, arresting sweating, softening liver, relieving pain and suppressing liver yang. It is commonly used for blood deficiency and chlorosis, irregular menstruation, spontaneous perspiration, night sweat, hypochondriac pain, abdominal pain, limb spasm and pain, headache and vertigo.

The selfheal contains components such as ursolic acid, oleanolic acid, caffeic acid, gallic acid, selfheal saponin A, selfheal saponin B, umbelliferone, oleic acid and the like, the black cluster contains lower amount of the ursolic acid, and the ursolic acid and the oleanolic acid can not be detected from roots, stems and leaves. Cold in nature, pungent and bitter in flavor. It enters liver meridian and gallbladder meridian. Clearing pathogenic fire, improving eyesight, resolving hard mass, and relieving swelling, and has effects of lowering blood pressure, resisting arrhythmia, resisting inflammation, suppressing immunity, lowering blood sugar, resisting bacteria, resisting virus, and resisting cytotoxicity.

Rhizoma Ligustici Chuanxiong contains ligustilide, 3-butylidenephthalide and sabinene as main ingredients, and also contains ferulic acid, indoline, 3-butylidene phthalide, myrcene, ligustrazine, palmitic acid, daucosterol, beta-sitosterol, etc. Warm in nature and pungent in flavor. It enters liver meridian, gallbladder meridian and pericardium meridian. Promote blood circulation and move qi, dispel wind and alleviate pain.

Achyranthes bidentata contains a large amount of alkaloids, and has the functions of tonifying liver and kidney, strengthening muscles and bones, dredging channels and collaterals and dissipating blood stasis. It is often used to treat cold-dampness, lumbago, gonalgia, spasm of limbs, menoxenia, puerperal blood stasis, abdominal pain, stranguria with blood, traumatic injury, and inflexion of knee.

The longan, the jujube kernel and the medlar are used together, and can be used for treating insomnia and improving the sleep quality of patients.

Semen astragali Complanati mainly contains triterpene glycoside, flavone, various glycosides, isoflavone glycoside, amino acids, various fatty acids, and abundant trace elements. Warm in nature and sweet in taste. It enters liver and kidney meridians. Has effects of warming and invigorating liver and kidney, arresting spontaneous emission, reducing urination, and improving eyesight, and can be used for treating kidney essence deficiency, nocturnal emission, spermatorrhea, soreness of waist, tinnitus, extremity debilitation, pale tongue with white fur, etc.

Tu Si Zi is pungent in flavor and warm in nature. It enters liver, kidney and spleen meridians. Has effects in invigorating kidney, nourishing liver, stopping nocturnal emission, reducing urination, improving eyesight, relieving diarrhea, and preventing miscarriage. It is combined with Shu Di Huang and Gou Qi to achieve the effects of tonifying kidney, nourishing essence, nourishing liver, improving eyesight, and treating liver and kidney deficiency. It is used with herba Cynomorii and Cistanchis herba to treat sexual impotence, premature ejaculation and female infertility due to kidney yang deficiency.

In some embodiments of the invention, the traditional Chinese medicine composition further comprises 1-20 parts of caulis spatholobi, 5-20 parts of red date, 10-15 parts of medicated leaven, 5-15 parts of endothelium corneum gigeriae galli, 12-20 parts of dried orange peel, 15-30 parts of Chinese yam, 5-15 parts of honey-fried licorice and 10-20 parts of fructus amomi by weight.

Caulis Spatholobi contains isoflavone, flavanone, chalcone, coumestrol, triterpene, sterol, epifriedelin alcohol, daucosterol, formononetin, epicatechin, aloe emodin, etc. Has effects in dilating blood vessel, inhibiting platelet aggregation, and promoting phosphorus metabolism.

Medicated leaven, yeast preparation, yeast, vitamin B complex, ergosterol, protein, fat, volatile oil, etc. Promoting digestion, eliminating food stagnation, invigorating spleen, regulating stomach function, stimulating appetite, and maintaining normal digestion, and can be used for treating food stagnation, dyspepsia, abdominal distention, anorexia, emesis, and dysentery.

Endothelium corneum Gigeriae Galli contains gastric juice essence, keratin, trace pepsin, amylase, and multiple vitamins. Various amino acids, and various trace elements. Mild in nature and sweet in taste. It enters spleen meridian, stomach meridian, small intestine meridian and bladder meridian. Has effects of invigorating stomach, resolving food stagnation, astringing essence, and relieving enuresis. Can be used for treating abdominal distention due to dyspepsia, regurgitation, nocturnal emission, etc.

Pericarpium Citri Tangerinae, contains volatile oil, hesperidin, n-decanal, citral, limonene, octanol, etc. Pungent and bitter in flavor and warm in nature. It enters spleen and lung meridians. Regulate qi-flowing for promoting appetite, dry dampness and resolve phlegm, treat spleen and stomach diseases.

The yam is a food material, and the yam powder used in the invention is obtained by crushing the yam and drying the yam.

Honey-fried licorice mainly contains liquiritin, glycyrrhizic acid, glycyrrhizin, syringene oxide, glycyrrhetin alcohol, 18-hydroxy glycyrrhetinic acid, isoglycyrrhetinic acid, glycyrrhetinic acid, coumarins, formononetin, neolicochalcone D, glabrene aglycone, isolicoflavonol, etc. Warm in nature and sweet in taste. They enter heart, lung, stomach and spleen meridians. Has the effects of invigorating spleen, regulating stomach function, benefiting qi and recovering pulse.

Sha ren, pungent in flavor and warm in nature. Has effects of eliminating dampness, promoting appetite, warming spleen, relieving diarrhea, regulating qi-flowing, and preventing miscarriage. Can be used for treating damp turbidity obstruction in middle energizer, abdominal distention, inappetence, deficiency-cold of spleen and stomach, emesis, diarrhea, vomiting, and threatened abortion.

In some embodiments of the invention, the medicine further comprises, by weight, 10-20 parts of honey-fried polygala tenuifolia, 5-15 parts of rhizoma acori graminei, 5-10 parts of fructus psoraleae, 5-20 parts of rhizoma drynariae, 5-10 parts of cajanus cajan leaves, 15-20 parts of rhizoma curculiginis, 18-25 parts of radix clematidis, 10-20 parts of pawpaw, 5-15 parts of cortex acanthopanacis, 10-15 parts of lopseed, 10-20 parts of lycopodium clavatum, 5-20 parts of polygonum cuspidatum, 5-20 parts of radix puerariae powder, 10-15 parts of rhizoma cibotii, 10-15 parts of salvia miltiorrhiza and 10-15 parts of kadsura pepper stem.

Polygala tenuifolia effective components are saponin, oroxanthone, oligosaccharide ester and alkaloid, and also contains Polygala tenuifolia alcohol, 3,4, 5-trimethoxy-cinnamic acid, stigmasterol, a-bromsterol glucoside-6' -palmitate, 2-hydroxy-4, 6-benzophenone, etc. Enter heart, kidney and lung meridians, induce tranquilization, improve intelligence and relieve depression. It is indicated for palpitation, amnesia, nocturnal emission, insomnia, cough with excessive phlegm, abscess, deep-rooted carbuncle, sore and swelling.

Rhizoma Acori Graminei has effects of eliminating dampness, promoting appetite, inducing resuscitation, eliminating phlegm, refreshing mind and improving intelligence. Can be used for treating epigastric fullness, inappetence, dysentery, coma, epilepsy, amnesia, and deafness. Regulating qi, promoting blood circulation, dispelling pathogenic wind, and removing dampness. It can be used for treating epilepsy, phlegm syncope, fever, coma, amnesia, qi block, deafness, vexation, gastralgia, abdominal pain, arthralgia due to wind-cold-dampness, superficial infection, toxic swelling, and traumatic injury.

Fructus Psoraleae has effects of invigorating kidney, supporting yang, arresting spontaneous emission, and reducing urination, and can be used for treating lumbago due to kidney deficiency, frequent micturition, infantile enuresis, renal leak, spleen warming, diarrhea relieving, and asthma relieving.

Rhizoma Drynariae containing naringin is hydrolyzed to obtain quercetin, D-glucose and L-rhamnose, and contains fractaloside and various tetrapentacriterpenes compounds. The content of naringin in rhizome of drynaria fortunei is measured to be about 1% by using a thin-layer ultraviolet spectrophotometry. In addition, it contains naringin, 21-hopanacene, cycloartocarsterol-acetate, cyclocarinol acetate, cycloartocarenol acetate, beta-sitosterol, and rhizoma Kaempferiae. Warm in nature and bitter in taste. It enters liver and kidney meridians. It is used to treat lumbago due to kidney deficiency, toothache, tinnitus, chronic diarrhea, traumatic injury, alopecia areata, clavus, etc.

Folium Cajani, light in flavor, neutral in nature, enters heart meridian, has the efficacy of detoxifying and reducing swelling, and is mainly used for treating chicken pox, carbuncle, swelling and sore toxicity in children.

Curculigo orchioides, polysaccharide glycosides mainly containing various cycloartane triterpenes and glycosides thereof, methyl phenol, curculigoside A, curculigoside B, lichenin glucoside, curculigoside, lycorine, daucosterol and chloromethylphenol, and has effects of warming and pungent taste, invigorating kidney, liver and spleen meridians, strengthening tendons and bones, and dispelling cold-dampness. Has effects of androgen-like and adaptogen, resisting aging, enhancing immunity, tranquilizing, relieving convulsion, resisting inflammation, androgen-like, enhancing immunity, improving adaptogen, improving function of hypothalamus-pituitary-gonad axis, and increasing Na⁺-K⁺ATP enzyme activity, antibiosis, blood sugar reduction, anticancer and other effects.

Folium Cajani, rhizoma Curculiginis and herba Epimedii can be used together to obtain ERXIAN decoction, which has effects of invigorating kidney, purging pathogenic fire, regulating Chong and ren meridians, arresting sweating, preventing miscarriage, and resisting cancer, and can be used for treating femoral head necrosis. Rhizoma Curculiginis in ERXIAN decoction has effects of improving enzyme activity, resisting bacteria and cancer.

The radix Clematidis contains oleanolic acid, hederagenin, radix Clematidis-23-0-arabinoside, anemonin, pulonolide, sterol, saccharide, saponin, lactone, phenol, amino acid, etc. Warm in nature, pungent and salty in flavor. It has effects of dispelling pathogenic wind, removing dampness, dredging collaterals and relieving pain, and can be used for treating rheumatalgia, numbness of limbs, spasm of tendons and vessels, difficulty in flexion and extension, and bone sticking throat. Has effects in relieving pain, resisting malaria, lowering blood sugar, promoting bile flow, improving esophageal peristalsis, softening fishbone, and relaxing throat, esophagus and smooth intestinal muscle.

Fructus Chaenomelis contains malic acid, tartaric acid, citric acid, ascorbic acid, fumaric acid and saponin; also contains potassium malate, oleanolic acid, ethyl chlorogenate, caffeic acid, chlorogenic acid, aconitic acid, flavone, tannin, etc., and fructus Chaenomelis has effects of protecting liver, resisting bacteria, and inhibiting tumor.

Cortex Acanthopanacis contains stearic acid, sesamin, beta-sitosterol, syringin, beta-sitosterol glucoside, etc. The composition also contains volatile oil, resin, syringin, eleutheroside, sessile acanthopanax root glycoside A, sessile acanthopanax root glycoside B, sessile acanthopanax root glycoside C, sessile acanthopanax root glycoside D, sessile acanthopanax root glycoside K2, sessile acanthopanax root glycoside K3, sessile acanthopanax root glycoside Bl, campesterol, 3-sitosterol glucoside, linolenic acid and other components, and has the functions of expelling wind-damp, nourishing liver and kidney, strengthening bones and muscles, resisting inflammation, resisting stress, resisting radiation and the like.

In some embodiments of the invention, the glutinous rice flour is further included according to parts by weight, and the mass ratio of the glutinous rice flour to the raw materials is (2-4): 1.

In some embodiments of the invention, the particle size of the powder is 80 mesh or smaller.

In some embodiments of the present invention, the method further comprises mixing the washed carapax et Plastrum Testudinis and carapax Trionycis with sand, parching in a pan until the surfaces of the carapax et Plastrum Testudinis and carapax Trionycis become yellow, soaking the carapax et Plastrum Testudinis and carapax Trionycis in white vinegar, drying, and mashing.

In some embodiments of the invention, the method further comprises drying the Chinese medicinal materials at 50-60 ℃ until the water content is less than 5 wt%.

In some embodiments of the invention, the method further comprises drying the prepared pellets to a moisture content of less than 1 wt%.

The features and properties of the present invention are described in further detail below with reference to examples.

Example 1

Preparing the Chinese medicinal materials according to the following mixture ratio:

10g of ginseng, 15g of gecko, 15g of penis cervi, 15g of cordyceps sinensis, 20g of pilose antler, 10g of hippocampus, 5g of syngnathus, 20g of dogwood, 10g of schisandra chinensis, 10g of dipsacus asperoides, 5g of eucommia ulmoides, 15g of tortoise plastron, 15g of turtle shell, 12g of cynomorium songaricum, 15g of epimedium herb, 10g of keel, 5g of calcined oyster shell, 15g of radix asparagi, 10g of prepared rehmannia root, 12g of angelica sinensis, 5g of poria cocos, 5g of astragalus membranaceus, 10g of medlar, 10g of cherokee rose fruit, 10g of sharpleaf galangal fruit, 10g of rhizoma polygonati, 15g of bighead atractylodes rhizome, 18g of white peony root, 20g of selfheal, 12g of ligusticum chuanxiong, 5g of achyranthes bidentata, 5g of longan, 5g of jujube kernel, 12g of flatstem, 12g of semen astragali complanati, 12g of dried fruit, 12g of cuscuta fruit, 5g of suberect spatholobus stem, 10g of red jujube, 10g of medicated leaven, 10g of endothelium corneum gigeriae galli, 15g of dried orange peel, 20g of Chinese yam, 15g of honey-fried licorice root, 15g of roasted liquorice and 10g of semen cuscutae.

Putting the Chinese medicinal material parts into an oven, drying at 50 +/-1 ℃ until the water content is less than 5 wt%, then crushing the medicinal materials, sieving with an 80-mesh sieve, selecting the part below the sieve, and further crushing the part above the sieve until all the medicinal materials are sieved.

And adding the glutinous rice flour into the pot, and adding water, wherein the mass ratio of the glutinous rice flour to the water is 1: 1. Decocting with strong fire for 5min, adding the pulverized medicinal powder, stirring, making into pill, and oven drying at 50 + -1 deg.C until the water content is less than 1 wt%. Wherein the mass ratio of the glutinous rice flour to the medicinal powder is 1: 2.

Example 2

15g of ginseng, 15g of gecko, 15g of penis cervi, 15g of cordyceps sinensis, 15g of pilose antler, 15g of hippocampus, 15g of syngnathus, 15g of dogwood, 15g of schisandra chinensis, 15g of dipsacus asperoides, 15g of eucommia ulmoides, 15g of tortoise plastron, 15g of turtle shell, 15g of cynomorium songaricum, 15g of epimedium herb, 15g of keel, 15g of calcined oyster shell, 15g of radix asparagi, 15g of prepared rehmannia root, 15g of angelica sinensis, 15g of poria cocos, 15g of astragalus membranaceus, 15g of medlar, 15g of cherokee rose fruit, 15g of sharpleaf galangal fruit, 15g of rhizoma polygonati, 15g of bighead atractylodes rhizome, 15g of white peony root, 15g of selfheal, 15g of ligusticum chuanxiong, 15g of achyranthes bidentata, 15g of longan, 15g of jujube kernel, 15g of flatstem, 15g of medicated leaven, 15g of endothelium corneum gigeriae galli, 15g of dried orange peel, 15g of Chinese yam, 15g of roasted liquorice and 15g of semen cuscutae.

Putting the Chinese medicinal material parts into an oven in batches, drying at 60 +/-1 ℃ until the water content is less than 5 wt%, then crushing the medicinal materials, sieving by a 80-mesh sieve, selecting the part below the sieve, and further crushing the part above the sieve until the whole part is sieved.

And adding the glutinous rice flour into the pot, and adding water, wherein the mass ratio of the glutinous rice flour to the water is 1: 1. Decocting with strong fire for 5min, adding the pulverized medicinal powder, stirring, making into pill, and oven drying at 50 + -1 deg.C until the water content is less than 1 wt%. Wherein the mass ratio of the glutinous rice flour to the medicinal powder is 1: 3.

Example 3

20g of ginseng, 5g of gecko, 5g of penis cervi, 10g of penis cervi, 5g of cordyceps sinensis, 8g of pilose antler, 1g of hippocampus, 1g of syngnathus, 25g of dogwood, 12g of schisandra chinensis, 20g of dipsacus asperoides, 5g of eucommia ulmoides, 20g of tortoise plastron, 20g of turtle shell, 14g of cynomorium songaricum, 12g of epimedium, 5g of keel, 15g of calcined oyster, 20g of radix asparagi, 5g of prepared rehmannia root, 10g of angelica sinensis, 1g of poria cocos, 1g of astragalus membranaceus, 25g of medlar, 10g of cherokee rose, 10g of sharpleaf galangal fruit, 20g of rhizoma polygonati, 18g of bighead atractylodes rhizome, 15g of white peony root, 15g of selfheal, 20g of ligusticum chuanxiong, 5g of achyranthes bidentata, 1g of longan, 1g of jujube kernel, 18g of flatstem, 15g of semen astragali complanati, 20g of spatholobus stem, 20g of red jujube, 12g of medicated leaven, 5g of endothelium corneum gigeriae galli, 12g of dried orange peel, 30g of Chinese yam, 5g of honey-fried licorice root, 5g of dodder and 20g of semen cuscutae.

Putting the Chinese medicinal material parts into an oven, drying at 55 +/-1 ℃ until the water content is less than 5 wt%, then crushing the medicinal materials, sieving with an 80-mesh sieve, selecting the part below the sieve, and further crushing the part above the sieve until all the medicinal materials are sieved.

And adding the glutinous rice flour into the pot, and adding water, wherein the mass ratio of the glutinous rice flour to the water is 1: 1. Decocting with strong fire for 5min, adding the pulverized medicinal powder, stirring, making into pill, and oven drying at 50 + -1 deg.C until the water content is less than 1 wt%. Wherein the mass ratio of the glutinous rice flour to the medicinal powder is 1: 4.

Example 4

12g of ginseng, 13g of gecko, 18g of penis cervi, 14g of cordyceps sinensis, 18g of pilose antler, 12g of hippocampus, 10g of syngnathus, 18g of dogwood, 12g of schisandra chinensis, 13g of dipsacus asperoides, 10g of eucommia ulmoides, 18g of tortoise plastron, 18g of turtle shell, 12g of cynomorium songaricum, 14g of epimedium, 13g of keel, 1g of calcined oyster, 18g of radix asparagi, 13g of prepared rehmannia root, 13g of angelica sinensis, 11g of poria cocos, 11g of astragalus membranaceus, 8g of medlar, 12g of cherokee rose fruit, 13g of sharpleaf galangal fruit, 8g of rhizoma polygonati, 13g of bighead atractylodes rhizome, 17g of white peony root, 18g of selfheal, 17g of ligusticum chuanxiong, 9g of achyranthes bidentata, 12g of longan, 1g of jujube kernel, 13g of flatstem, 15g of semen astragali complanati, 4g of suberect spatholobus stem, 8g of red jujube, 15g of medicated leaven, 12g of endothelium corneum gigeriae galli, 18g of dried orange peel, 25g of Chinese yam, 14g of honey-fried licorice root, and 16g of dodder.

The preparation method is the same as that of example 1.

Example 5

On the basis of the embodiment 1, the method also comprises the following raw materials:

15g of honey-fried polygala tenuifolia, 10g of rhizoma acori graminei, 8g of fructus psoraleae, 15g of rhizoma drynariae, 10g of cajanus cajan leaves, 15g of rhizoma curculiginis, 20g of radix clematidis, 15g of pawpaw, 10g of cortex acanthopanacis, 15g of garden balsam stem, 15g of lycopodium clavatum, 15g of polygonum cuspidatum, 15g of radix puerariae powder, 15g of rhizoma cibotii, 10g of salvia miltiorrhiza and 10g of kadsura pepper stem.

Examples of the experiments

40 patients were randomly selected and showed impotence, premature ejaculation and spermatorrhea. The results of the treatment of 40 patients randomly divided into 4 groups, and administered the Chinese medicinal composition of examples 1-4 2 times a day, 2g each time, continuously for 30 days, were summarized in Table 1.

TABLE 1 treatment of pills of examples 1-4

	Display effect (human)	Effective (human)	Invalid (human)
				Example 1	9	1	0
Example 2	8	2	0
				Example 3	9	1	0
Example 4	8	1	1

Wherein, in the table 1, the significant effect means that the symptoms of impotence, premature ejaculation and spermatorrhea are obviously improved or cured; the effective means that the symptoms of impotence, premature ejaculation and spermatorrhea are improved; the ineffectiveness means that the symptoms of impotence, premature ejaculation and spermatorrhea are not improved.

20 patients were randomly selected and had a clinical manifestation of femoral head necrosis. After the administration of 3g of the Chinese medicinal composition of example 5 2 times a day for 30 days, the treatment condition of each patient was counted, and the results are shown in Table 2.

TABLE 2 treatment of the pills of examples 1-4

	Display effect (human)	Effective (human)	Invalid (human)
				Example 1	18	1	1

Wherein, in the table 2, significant effect means that the symptoms of femoral head necrosis factor are obviously improved or cured; effective means that the symptoms of femoral head necrosis are improved; null refers to no improvement in symptoms of femoral head necrosis.

As can be seen from table 2, the femoral head necrosis of example 5 has a certain therapeutic effect, and the therapeutic effect is significant when the femoral head necrosis is treated by tonifying the kidney, nourishing the five internal organs and combining with the "erxian" decoction, and the therapeutic rate reaches over 90%.

The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims

1. The kidney-tonifying traditional Chinese medicine composition is characterized by comprising the following raw materials in parts by weight:

2. The kidney-tonifying traditional Chinese medicine composition as claimed in claim 1, further comprising the following raw materials in parts by weight: 1-15 parts of calcined oyster, 15-20 parts of radix asparagi, 5-15 parts of prepared rhizome of rehmannia, 10-15 parts of angelica, 1-20 parts of tuckahoe, 1-20 parts of astragalus, 5-25 parts of medlar, 10-15 parts of cherokee rose fruit and 10-15 parts of sharpleaf galangal fruit.

3. The kidney-tonifying traditional Chinese medicine composition as claimed in claim 2, further comprising the following raw materials in parts by weight:

5-20 parts of rhizoma polygonati, 12-18 parts of bighead atractylodes rhizome, 15-18 parts of white peony root, 15-20 parts of selfheal, 10-20 parts of ligusticum wallichii, 5-15 parts of radix achyranthis bidentatae, 1-15 parts of longan, 1-15 parts of jujube kernel, 12-18 parts of flatstem milkvetch seed and 12-15 parts of semen cuscutae.

4. The kidney-tonifying traditional Chinese medicine composition as claimed in claim 3, further comprising the following raw materials in parts by weight:

1-20 parts of caulis spatholobi, 5-20 parts of red dates, 10-15 parts of medicated leaven, 5-15 parts of endothelium corneum gigeriae galli, 12-20 parts of dried orange peel, 15-30 parts of Chinese yam, 5-15 parts of honey-fried liquorice and 10-20 parts of fructus amomi.

5. The kidney-tonifying traditional Chinese medicine composition as claimed in claim 4, further comprising the following raw materials in parts by weight:

10-20 parts of honey-fried polygala tenuifolia, 5-15 parts of rhizoma acori graminei, 5-10 parts of fructus psoraleae, 5-20 parts of rhizoma drynariae, 5-10 parts of cajan leaves, 15-20 parts of rhizoma curculiginis, 18-25 parts of radix clematidis, 10-20 parts of pawpaw, 5-15 parts of cortex acanthopanacis, 10-15 parts of garden balsam stem, 10-20 parts of lycopodium clavatum, 5-20 parts of polygonum cuspidatum, 5-20 parts of radix puerariae powder, 10-15 parts of rhizoma cibotii, 10-15 parts of salvia miltiorrhiza and 10-15 parts of kadsura pepper stem.

6. A method for preparing the kidney-tonifying traditional Chinese medicine composition as claimed in claim 5, which comprises the following steps: making the raw materials into medicinal powder, mixing Oryza Glutinosa powder with water, decocting with strong fire for 5-10min, adding the medicinal powder, and making into pill.

7. The method for preparing a kidney-tonifying Chinese medicinal composition according to claim 6, wherein the particle size of the medicinal powder is not more than 80 meshes.

8. The method for preparing a kidney-tonifying Chinese medicinal composition according to claim 6, further comprising mixing the washed tortoise plastron and turtle shell with sand, parching in a pan until the surfaces of the tortoise plastron and turtle shell become yellow, soaking the tortoise plastron and turtle shell in white vinegar, drying, and mashing.

9. The method for preparing a kidney-tonifying Chinese medicinal composition according to claim 6, further comprising drying the Chinese medicinal materials at 50-60 ℃ until the water content is less than 5 wt%.

10. The method for preparing a kidney-tonifying traditional Chinese medicine composition as claimed in claim 6, further comprising drying the prepared pills until the water content is less than 1 wt%.