CN102068625B - Traditional Chinese medicinal composition for reducing blood sugar and blood pressure and preparation method thereof - Google Patents
Traditional Chinese medicinal composition for reducing blood sugar and blood pressure and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicinal composition for reducing blood sugar and blood pressure and a preparation method thereof. The traditional Chinese medicinal composition comprises ginseng, glossy ganoderma, yam, acanthopanax bark, astragalus, largehead atractylodes rhizome, medlar, solomonseal rhizome, sea horse, atractylodes rhizome, pseudo-ginseng, kudzuvine root, goldthread, prepared rehmannia root, fragrant solomonseal rhizome, dendrobium, dwarf lilyturf tuber, tuber fleeceflower root, poria, anemarrhena, tall gastrodia tuber, Chinese magnoliavine fruit, epimedium, bee glue, mulberry leaves and other traditional Chinese medicinal materials; and the traditional Chinese medicinal composition can be prepared into various formulations through operable processes. The traditional Chinese medicinal composition has the curative effects of strengthening spleen and nourishing yin, benefiting qi and nourishing blood, reducing blood sugar and blood pressure, improving immunity and the like, is simple in process and low in cost, and is suitable for medicating diabetes and hypertension patients, particularly middle aged and old people.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition with blood sugar lowering hypotensive effect.
Background technology
Diabetes spp is in traditional traditional Chinese medical science " diabetes " category; China diabetes patient nearly 100,000,000; The hypertensive patient has reached 1.6 hundred million, and these two types of diseases have been sure to occupy ill front two, and along with the raising of living standards of the people, the change and the aged tendency of population of life style; Diabetes and hypertension prevalence increase with surprising rapidity year by year again, have become the follow-up disease of the serious harm human health after cardiovascular, cancer.
According to statistics, in whole treatment diabetes and hypertension drug market, Western medicine has occupied 80% of the market share, and Chinese medicine only accounts for about 20%.Western medicine is the main force of these two types of diseases of treatment, but it can't thoroughly cure, and side effect is big, and expense is high, has become a megalith of medical profession and consumer mind.And treatment by Chinese herbs has blood sugar lowering hypotensive effect gentleness lastingly, and toxicity and untoward reaction are little, and unique advantages such as treating both the principal and secondary aspects of a disease can delay the generation and the development of complication effectively, can yet be regarded as and seeks the important channel that blood sugar lowering has the medicine of hypotensive effect simultaneously concurrently.
The present invention aims to provide the Chinese medicine compound of a kind of hypoglycemic blood pressure lowering simultaneously, does not see the report of relevant compound recipe at present.
Summary of the invention
The purpose of this invention is to provide a kind of blood sugar lowering Chinese hypotensor compositions.
Another object of the present invention provides blood sugar lowering Chinese hypotensor preparation of compositions method.
Another object of the present invention provides a kind of effectively preparation of the Chinese medicine composition of blood sugar lowering blood pressure.
The present invention also provides a kind of method for preparing of Chinese medicinal composition preparation of blood sugar lowering blood pressure lowering.
The Chinese medicine composition of a kind of blood sugar lowering blood pressure lowering provided by the invention contains following Chinese medicine: Radix Ginseng, Ganoderma, Rhizoma Dioscoreae, Cortex Acanthopancis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Fructus Lycii, Rhizoma Polygonati, Hippocampus, Rhizoma Atractylodis, Radix Notoginseng, Radix Puerariae, Rhizoma Coptidis, Radix Rehmanniae Preparata, Rhizoma Polygonati Odorati, Herba Dendrobii, Radix Ophiopogonis, Radix Polygoni Multiflori, Poria, the Rhizoma Anemarrhenae, Rhizoma Gastrodiae, Fructus Schisandrae Chinensis, Herba Epimedii.
The Chinese medicine composition of a kind of blood sugar lowering blood pressure lowering provided by the invention contains following parts by weight of Chinese traditional medicine: Radix Ginseng 30-50 part, Ganoderma 20-40 part, Rhizoma Dioscoreae 55-80 part, Cortex Acanthopancis 20-40 part; Radix Astragali 50-75 part, Rhizoma Atractylodis Macrocephalae 60-100 part, Fructus Lycii 35-60 part, Rhizoma Polygonati 35-60 part, Hippocampus 15-40 part; Rhizoma Atractylodis 25-55 part, Radix Notoginseng 25-55 part, Radix Puerariae 40-70 part, Rhizoma Coptidis 40-70 part, Radix Rehmanniae Preparata 40-70 part; Rhizoma Polygonati Odorati 25-55 part, Herba Dendrobii 40-70 part, Radix Ophiopogonis 50-80 part, Radix Polygoni Multiflori 25-55 part; Poria 20-45 part, Rhizoma Anemarrhenae 20-45 part, Rhizoma Gastrodiae 10-22 part, Fructus Schisandrae Chinensis 20-45 part and Herba Epimedii 10-22 part.
The Chinese medicine composition of a kind of blood sugar lowering blood pressure lowering provided by the invention contains following parts by weight of Chinese traditional medicine: Radix Ginseng 40-50 part, Ganoderma 25-35 part, Rhizoma Dioscoreae 60-70 part, Cortex Acanthopancis 25-35 part; Radix Astragali 55-65 part, Rhizoma Atractylodis Macrocephalae 70-90 part, Fructus Lycii 40-55 part, Rhizoma Polygonati 40-55 part, Hippocampus 20-30 part; Rhizoma Atractylodis 30-50 part, Radix Notoginseng 30-50 part, Radix Puerariae 50-60 part, Rhizoma Coptidis 50-60 part, Radix Rehmanniae Preparata 50-60 part; Rhizoma Polygonati Odorati 30-50 part, Herba Dendrobii 50-60 part, Radix Ophiopogonis 60-70 part, Radix Polygoni Multiflori 30-50 part; Poria 25-35 part, Rhizoma Anemarrhenae 25-35 part, Rhizoma Gastrodiae 15-20 part, Fructus Schisandrae Chinensis 25-35 part and Herba Epimedii 15-20 part.
The Chinese medicine composition of a kind of blood sugar lowering blood pressure lowering provided by the invention contains the Chinese medicine of following mass percent: 44 parts of Radix Ginsengs, 29 parts of Ganodermas, 65 parts of Rhizoma Dioscoreaes, 29 parts of Cortex Acanthopanciss, 60 parts of the Radixs Astragali; 29 parts of the Rhizoma Atractylodis Macrocephalaes, 48 parts of Fructus Lycii, 48 parts of Rhizoma Polygonatis, 24 parts of Hippocampus, 39 parts of Rhizoma Atractylodis, 39 parts of Radix Notoginseng; 55 parts of Radix Puerariaes, 55 parts of Rhizoma Coptidis, 55 parts of Radix Rehmanniae Preparata, 39 parts of Rhizoma Polygonati Odorati, 55 parts of Herba Dendrobiis, 65 parts of Radix Ophiopogonis; 39 parts of Radix Polygoni Multiflori, Poria 32,32 parts of the Rhizoma Anemarrhenaes, 16 parts in Rhizoma Gastrodiae, 32 parts of Fructus Schisandrae Chinensis, 16 parts of Herba Epimedii.
A kind of blood sugar lowering Chinese hypotensor compositions provided by the invention also contains 35 parts on 20 parts of propolis and Folium Mori.
The present invention also provides a kind of preparation blood sugar lowering Chinese hypotensor method for compositions, it is characterized in that, may further comprise the steps:
1) takes by weighing above-mentioned 23 flavor Chinese crude drugs according to proportioning, use the clear water cleaning, drying;
2) Radix Ginseng, Ganoderma, the Radix Astragali, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae, Radix Puerariae Six-element medicated powder are broken into smalls, sieve;
3) with remaining 17 flavor Chinese medicine decocte with water secondary, collecting decoction filters, and filtrating is condensed into extractum;
4) with extractum and step 2 in the step 3)) in the powder mixing, promptly get.
The present invention also provides a kind of preparation blood sugar lowering Chinese hypotensor method for compositions, it is characterized in that, may further comprise the steps:
1) takes by weighing above-mentioned 25 flavor Chinese crude drugs according to proportioning, use the clear water cleaning, drying;
2) Radix Ginseng, Ganoderma, the Radix Astragali, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae, Radix Puerariae Six-element medicated powder are broken into smalls, sieve;
3) with remaining 19 flavor Chinese medicine decocte with water secondary, collecting decoction filters, and filtrating is condensed into extractum, adds step 2) in powder, mixing promptly gets.
The present invention also provides a kind of method for preparing of Chinese medicine composition of blood sugar lowering blood pressure lowering, it is characterized in that, may further comprise the steps:
1) takes by weighing above-mentioned 25 flavor Chinese crude drugs according to proportioning, wash 4-5 time, put into dehydrator 70-90 ℃ of oven dry 20-30 minute with clear water;
2) Radix Ginseng, Ganoderma, the Radix Astragali, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae, Radix Puerariae Six-element medicated powder are broken into smalls, cross 100 mesh sieves;
3) with remaining 19 flavor Chinese medicine decocte with water secondary, add 10 times of water gagings for the first time and decocted 2 hours, add 8 times of water gagings the second time and decocted 1 hour, collecting decoction filters, and it is the extractum of 1.30-1.35 that filtrating is concentrated into 50 ℃ of heat survey relative densities;
4) with extractum and step 2) in the powder mixing, promptly get.
The invention provides a kind of preparation of blood sugar lowering Chinese hypotensor compositions, said preparation is made up of active component and pharmaceutically acceptable carrier or diluent.
Said preparation is solid preparation or liquid preparation, and solid preparation is selected from sheet, ball, powder, capsule or granule, and liquid preparation is selected from oral liquid.
Said pharmaceutically acceptable carrier or diluent are selected from one or more in starch, dextrin, microcrystalline Cellulose, Pulvis Talci, the magnesium stearate.
The present invention also provides a kind of method for preparing of preparation of blood sugar lowering Chinese hypotensor compositions, may further comprise the steps: with extract, 70-90 ℃ dry down, is ground into fine powder, with the appropriate amount of auxiliary materials mixing, adopts common process to be prepared into conventional formulation.
Common dose of the present invention is every day 2 times, in the each 0.5-10g of crude drug amount.
In the Chinese medicine composition of the present invention:
Radix Ginseng (Radix Ginseng) is the root of Araliaceae Radix Ginseng; The property flat, sweet in the mouth, little hardship, tepor.Return spleen, lung meridian; Its merit focuses on the gas of big revisal unit, with strong life this, and then take off admittedly, benefit decreases, quenches the thirst, calms the nerves, so all deficiency syndrome of men and women, the yang blood and qi various symptoms and signs of deficiency all can be used, and is asthenia internal injury first key medicine; Modern pharmacological research thinks that Radix Ginseng has has sedation, the adaptability that improves body, protection, blood sugar lowering, blood pressure lowering and the effects such as blood fat, shock to cardiac muscle to the central nervous system.
Ganoderma (Ganoderma lucidum) claim Ganoderma lucidum (Leyss. Ex Fr.) Karst., Ganoderma lucidum seu Japonicum, Ganoderma, ZHICAO, Herba mesonae chinensis, Ganoderma again, is the Herb of Polyporaceae plant Ganoderma lucidum (Leyss. Ex Fr.) Karst. or Ganoderma; Nature and flavor are sweet, and are flat.GUIXIN, lung, liver, kidney channel.Cure mainly asthenia, cough, asthma, insomnia, dyspepsia, malignant tumor etc.; Modern pharmacological research thinks, Ganoderma has blood sugar lowering, antitumor, protecting liver and detoxication, cardiovascular system had effect, defying age and the neurasthenia effect of protecting myocardial cell and blood fat reducing, vessel softening.
Rhizoma Dioscoreae (Dioscorea opposita) claims that again Rhizoma Dioscoreae, RHIIZOMA DIOSCOREAE frOm Henan of China, Rhizoma dioscoreae, native potato, mountain potato, jade prolong, and are commonly referred to as Rhizoma Dioscoreae; Overgrow the for many years tuber of herbaceous plant Rhizoma Dioscoreae of Dioscoreaceae; Nature and flavor are sweet, warm, flat, nontoxic, have spleen invigorating, and tonifying the lung is reinforced the kidney, the effect that benefit is smart; Modern pharmacological research think have arthritis, hypoglycemic effect.
Cortex Acanthopancis (Radix Acanthopanacis Senticosl) has another name called CORTEX ACANTHOPANACIS, grain rice skin, Radix Tetrastigmatis Obovati skin, and the Araliaceae undershrub hitches the root bark of slender acanthopanax; Property and flavor of peppery and warm is eaten, kidney two warps; Effect is a curing rheumatism, strengthening bone and muscle; Modern pharmacological research has the effect that expands blood vessel, blood pressure lowering, blood sugar lowering, anti-inflammatory and analgesic effect, anti-stress effect and increase immunity;
The Radix Astragali (Astragali radix) is the dry root of leguminous plant Radix Astagali or Radix Astragali, nature and flavor: sweet, tepor, return through: return lung, spleen, liver, kidney channel; The Radix Astragali has benefiting QI for strengthening the superficies, arresting sweating to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema admittedly.Modern pharmacological research is thought: the Radix Astragali has raise immunity; Enhancing body anoxia enduring and stress ability; Promote organism metabolism; Improve cardiac function; Hypotensive effect; Hepatoprotective effect; Effects such as blood sugar regulation;
The Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae) is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..Bitter in the mouth, sweet, warm in nature, return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Be used for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement; Modern pharmacological research thinks that the Rhizoma Atractylodis Macrocephalae has gastric emptying and intestinal propulsion function, the antiulcer of promotion, prevents effects such as hepatic injury, enhancing human body immunity function, anti-stress, enhancing hemopoietic function, diuresis, blood sugar lowering, anticoagulation.
Fructus Lycii (Lycii fructus) is the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L., sweet in the mouth; Property is put down, and returns liver, kidney, lung meridian.Has nourishing the liver; Nourishing kidney; The effect of lung moistening, modern pharmacology research thinks that Fructus Lycii has immunologic function, delaying sanility, anti-liver injury, blood sugar lowering, the kidney invigorating, blood pressure lowering, fatigue-resisting function.
Rhizoma Polygonati (Polygonati falcatirhizoma) is the dry rhizome of liliaceous plant Yunnan Rhizoma Polygonati, Rhizoma Polygonati or Polygonatum cyrtonema Hua, sweet in the mouth, and property is flat.Return lung, spleen, kidney channel, have nourishing kidney profit spleen, the effect of invigorating the spleen and replenishing QI; Modern pharmacological research thinks that Rhizoma Polygonati has effects such as resisting pathogenic microbes, blood sugar lowering, resisting fatigue, antioxidation, slow down aging.
Hippocampus, sweet in the mouth, warm in nature, have the effect of kidney invigorating and YANG supporting, eliminating mass abdominal mass, modern pharmacological research thinks that Hippocampus has gonadotropic Effect, but defying age is anticancer.
Rhizoma Atractylodis (Rhizoma Atractylodis) are rhizome such as dicotyledon medicine feverfew RHIZOMA ATRACTYLODIS IANCEAE or Atractylis chinensis, and acrid in the mouth, hardship are warm in nature, return spleen, stomach, Liver Channel, have drying damp and strengthening spleen, expelling wind and cold, the effect of item; Modern pharmacology think Rhizoma Atractylodis can regulating gastointestinal motor function, antiulcer, protect the liver, effects such as blood sugar lowering, antitumor.
Radix Notoginseng (Panax Notoginseng), warm in nature, sweet in the mouth, little hardship have dissipating blood stasis hemostasis, the effect of subduing swelling and relieving pain, be mainly used in various inside and outside hemorrhage, breast ventral spine pain, tumbling and swelling; Modern pharmacological research thinks that Radix Notoginseng has good hemostasia effect, significant hemopoietic function, can tighten and improve the microcirculatory effect of arteria coronaria, and blood sugar regulation improves sleep, improves the nutrition anemia.
Radix Puerariae (Puerariae radix), cool in nature for the dry root of legume pueraria lobata or Radix Puerariae rattan, sweet in the mouth, suffering.Having induces sweat brings down a fever, promote the production of body fluid, rash, yang invigorating antidiarrheal effect, be mainly used in fever caused by exogenous pathogens headache, hypertension neck pain, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, have loose bowels.Modern pharmacology thinks that Radix Puerariae has blood pressure lowering, blood sugar lowering, blood fat reducing and improves the effect of cardiovascular and cerebrovascular disease.
Rhizoma Coptidis (Coptidis rhizoma), the dry rhizome of Coptis deltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall, bitter in the mouth, cold in nature, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel have heat clearing and damp drying, the effect of eliminating fire and detoxication.Be mainly used in 1) damp and hot feeling of fullness, the vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, the carbuncle furuncle is quenched one's thirst in toothache; 2) external treatment eczema, eczema, auditory meatus is suppurated.The kind clear part of the body cavity above the diaphragm housing the heart and lungs of Rhizoma Coptidis (processed with wine) is burning hot.Be used for conjunctival congestion, aphtha.Modern pharmacological research thinks that Rhizoma Coptidis has the effect of resisting pathogenic microbes, arrhythmia, blood pressure lowering, enhancing positive inotropic, detoxifcation, anticoagulant.
Radix Rehmanniae Preparata is concocted the tuber that forms plant for the tuber of scrophulariaceae rehmannia glutinosa plant and is formed sweet in the mouth through processing steaming solarization through processing; Warm in nature; Have and enrich blood moistly, beneficial essence is filled out the effect of marrow, modern study; The contained Dihuang polysaccharide of Radix Rehmanniae Preparata has tangible immune antitumor activity, also has significant heart tonifying, diuresis, protects the liver, effects such as blood sugar lowering, anti-hypertrophy, exudation, antiinflammatory, antifungal, anti-radiation.
Rhizoma Polygonati Odorati (Polygonatum odoratum), sweet in the mouth, property is flat.Return lung; The stomach warp.Nourishing YIN and moistening the lung; Nourishing the stomach to promote the production of body fluid.Cough caused by dryness; Chronic cough; The dry throat and mouth of the cloudy liquid consumption of calentura wound; Interior-heat is quenched one's thirst; Deficiency of YIN diseases caused by exogenous pathogenic factor; Dizzy dizzy; Muscle arteries and veins spasm and pain.Modern pharmacological research thinks that Rhizoma Polygonati Odorati has heart tonifying, blood sugar lowering, raising serum hemolysin antibody horizontal, improves the effect of splenocyte to the breeder reaction of ConA.
Herba Dendrobii (Dendrobium), meridian distribution of property and flavor: be slightly cold; Sweet; Return stomach, kidney channel, function cures mainly: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Be used for cloudy impairment of body fluid and lose, the xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision; Modern pharmacological research thinks that Herba Dendrobii has analgesic antiinflammatory, facilitating digestion, blood pressure lowering and blood glucose effect.
Radix Ophiopogonis (Radix Ophiopogonis), be the Liliaceae Ophiopogon plant dried root of Radix Ophiopogonis.Sweet in the mouth, little hardship, cold nature, GUIXIN, lung, stomach warp; Function with cure mainly: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Be used for dryness of the lung dry cough, the chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria; Modern pharmacological research think blood sugar lowering Radix Ophiopogonis, improve hypoxia-bearing capability, strengthen heart contractility, improve the cardiac hemodynamics effect, effect such as ARR generation after the prevention myocardial infarction.
Radix Polygoni Multiflori (Fallopia multiflora) function cures mainly: detoxifcation, eliminating carbuncle, loosening bowel to relieve constipation.Be used for the scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; Hyperlipidemia, hyperglycemia.
Poria (Poria cocos), sweet in the mouth, light, property are flat, GUIXIN warp, lung meridian, spleen channel, kidney channel; Effect with promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Modern medicine study: Poria ability enhancing human body immunity function, effects such as blood sugar lowering.
The Rhizoma Anemarrhenae (Anemarrhena asphodeloides), bitter in the mouth, sweet, cold in nature.Return lung, stomach, kidney channel.Function cures mainly: clearing away heat-fire, and promote the production of body fluid and moisturize, the external treatment fever caused by exogenous pathogenic factors, the hyperpyrexia excessive thirst, the treatment by oral administration of medicines cough due to lung-heat, gastric heat is quenched one's thirst; The xeropulmonary cough; The dryness of the intestine constipation; Osteopyrexia and fever; Modern pharmacological research thinks that the Rhizoma Anemarrhenae has effects such as antibiotic, antifungal, radioprotective, blood sugar lowering.
Rhizoma Gastrodiae (Gastrodia elata Blume), Rhizoma Gastrodiae embellishes but not dry, and the master goes into Liver Channel, is longer than suppressing the hyperactive liver to relieve the wind syndrome, and the disease of all liver-wind stirring up internallys, the vertigo is no matter deficiency and excess is key medicine.Modern pharmacological research thinks that Rhizoma Gastrodiae has calmness, syngignoscism to nervus centralis, and cardiovascular is had blood pressure lowering, decreased heart rate, the kinemic effect of increase.
Fructus Schisandrae Chinensis (Fructus Schisandrae Chinensis), for magnoliaceae schisandra is practised title " Radix Schisandrae Bicoloris ", or schisandra chinensis is practised the dry mature fruit of claiming " Fructus Schisandrae Sphenantherae "; Sour in the mouth, sweet, warm in nature, return lung, the heart, kidney channel; It is astringent or styptic treatment for spontaneous sweating to have convergence, supplementing QI for promoting the production of body fluid, and the effect of kidney calming is mainly used in the chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia; Modern pharmacological research thinks and protects the liver and the liver organization of regenerating, antiinflammatory, blood sugar lowering, protect and increase before effect such as heart body.
Herba Epimedii (Herba Epimedii) has another name called Herba Epimedii, and acrid in the mouth, sweet is warm in nature, returns liver, kidney channel; Have kidney-replenishing, bone and muscle strengthening, the effect of wind-damp dispelling is mainly used in impotence and seminal emission, and the muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Propolis, bitter in the mouth, suffering, cold in nature are returned spleen, stomach warp; Tonify deficiency for oral administration is weak, change turbid fat, only quench one's thirst; The external removing toxic substances and promoting subsidence of swelling.For oral administration be used for body empty senilism, hyperlipemia, quench one's thirst; External treatment is used for chapped skin, burn and scald.
Folium Mori (Folium Mori) are the dried leaves of moraceae plants Mulberry, sweet in the mouth, hardship; Cold in nature.Return lung, Liver Channel.Has dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing liver-YANG, liver heat removing and eyesight improving.Modern pharmacological research thinks that Folium Mori have spasmolytic, resisting pathogenic microbes, antiinflammatory, blood sugar lowering, blood pressure lowering, inhibition smooth muscle, blood fat reducing, diuretic actions.
Above-mentioned 25 flavor Chinese medicines play the blood sugar lowering hypotensive effect jointly.
The Chinese medicine composition of a kind of blood sugar lowering blood pressure lowering provided by the invention has following advantage:
1, utilization Chinese herb prevention chronic complicating diseases, and the medicine source is wide, cost hangs down duration of efficacy length, treatment diabetes evident in efficacy, hypertensive medicine;
2, several Chinese crude drugs and conventional machining process have been adopted; Its goods include multiple blood sugar lowering blood pressure lowering and prevent and treat the ingredient of multiple complications; Prescription is rigorous, and duration of efficacy is long and evident in efficacy, safe and reliable; Have the effect of treatment multinomial diabetes, hypertension and complication thereof, removed patient's misery.
The specific embodiment
Following examples are used to explain the present invention, but are not used for limiting scope of the present invention.
Embodiment 1: tablet
1, Chinese medicine ingredients: Radix Ginseng 140g, Ganoderma 90g, Rhizoma Dioscoreae 200g, Cortex Acanthopancis 90g, Radix Astragali 190g, Rhizoma Atractylodis Macrocephalae 250g, Fructus Lycii 150g; Rhizoma Polygonati 150g, Hippocampus 75g, Rhizoma Atractylodis 130g, Radix Notoginseng 130g, Radix Puerariae 180g, Rhizoma Coptidis 180g; Radix Rehmanniae Preparata 180g, Rhizoma Polygonati Odorati 130g, Herba Dendrobii 130g, Radix Ophiopogonis 200g, Radix Polygoni Multiflori 130g, Poria 100g; Rhizoma Anemarrhenae 100g, Rhizoma Gastrodiae 50g, Fructus Schisandrae Chinensis 100g, Herba Epimedii 50g, propolis 56g, Folium Mori 70g.
2, method for preparing
1) according to above-mentioned prescription proportioning, take by weighing Radix Ginseng 140g, Ganoderma 90g, Radix Astragali 190g, Fructus Schisandrae Chinensis 100g, Rhizoma Dioscoreae 200g, Radix Puerariae 180g, wash 5 times with clear water, dried 30 minutes for 80 ℃, be ground into smalls and cross 100 mesh sieves, subsequent use;
2) take by weighing all the other 19 flavors in the prescription, mixing and water adding decocts secondary, adds 10 times of water gagings for the first time and decocts 2 hours, adds 8 times of water gagings for the second time and decocts 1 hour, and collecting decoction filters, and filtrating is concentrated into 50 ℃ of heat and surveys relative density 1.30-1.35, and is subsequent use.
3) with powder 1) adding extractum 2) in, fully stirring, drying under reduced pressure is ground into fine powder, and the softgel shell of packing into adds starch and processes capsule, or adds starch 250g, dextrin 50g, Pulvis Talci 50g makes wetting agent with an amount of 70% ethanol, granulates, dries, and is pressed into tablet.
Embodiment 2: tablet
1, Chinese medicine ingredients: Radix Ginseng 140g; Ganoderma 75g; Rhizoma Dioscoreae 180g; Cortex Acanthopancis 90g; Radix Astragali 150g; Rhizoma Atractylodis Macrocephalae 200g; Fructus Lycii 150g; Rhizoma Polygonati 120g; Hippocampus 75g; Rhizoma Atractylodis 100g; Radix Notoginseng 130g; Radix Puerariae 150g; Rhizoma Coptidis 150g; Radix Rehmanniae Preparata 150g; Rhizoma Polygonati Odorati 110g; Herba Dendrobii 130g; Radix Ophiopogonis 170g; Radix Polygoni Multiflori 130g; Poria 100g; Rhizoma Anemarrhenae 100g; Rhizoma Gastrodiae 40g; Fructus Schisandrae Chinensis 100g; Herba Epimedii 50g; Propolis 56g; Folium Mori 70g.
2, method for preparing:
1) take by weighing Radix Ginseng 140g, Ganoderma 75g, Radix Astragali 150g, Fructus Schisandrae Chinensis 100g, Rhizoma Dioscoreae 180g, Radix Puerariae 150g according to prescription, wash 4 times, dried 20 minutes down for 80 degrees centigrade, be ground into smalls and cross 100 mesh sieves with clear water, subsequent use;
2) take by weighing all the other 19 flavors in the prescription, mixing and water adding decocts secondary, adds 10 times of water gagings for the first time and decocts 2 hours, adds 8 times of water gagings for the second time and decocts 1 hour, and collecting decoction filters, and filtrating is concentrated into 50 ℃ of heat and surveys relative density 1.30-1.35, and is subsequent use;
3) with powder 1) adding extractum 2) in, fully stirring, drying under reduced pressure is ground into fine powder, and the softgel shell of packing into adds starch and processes capsule, or adds starch 200g, dextrin 40g, Pulvis Talci 45g makes wetting agent with an amount of 70% ethanol, granulates, dries, and is pressed into tablet.
Embodiment 3:
1, Chinese medicine ingredients: Radix Ginseng 120g; Ganoderma 90g; Rhizoma Dioscoreae 200g; Cortex Acanthopancis 100g; Radix Astragali 180g; Rhizoma Atractylodis Macrocephalae 200g; Fructus Lycii 150g; Rhizoma Polygonati 120g; Hippocampus 90g; Rhizoma Atractylodis 120g; Radix Notoginseng 130g; Radix Puerariae 150g; Rhizoma Coptidis 150g; Radix Rehmanniae Preparata 150g; Rhizoma Polygonati Odorati 120g; Herba Dendrobii 120g; Radix Ophiopogonis 180g; Radix Polygoni Multiflori 120g; Poria 120g; Rhizoma Anemarrhenae 100g; Rhizoma Gastrodiae 50g; Fructus Schisandrae Chinensis 100g; Herba Epimedii 50g; Propolis 56g; Folium Mori 70g.
2, method for preparing:
1) take by weighing Radix Ginseng 120g, Ganoderma 90g, Radix Astragali 180g, Fructus Schisandrae Chinensis 100g, Rhizoma Dioscoreae 200g, Radix Puerariae 150g in the compound recipe, wash 5 times with clear water, 80 degrees centigrade of oven dry 25 minutes down are ground into smalls and cross 100 mesh sieves, and are subsequent use;
2) get 19 flavors such as all the other prescription Cortex Acanthopancis 100g, Rhizoma Atractylodis Macrocephalae 200g, mixing and water adding decocts secondary, adds 10 times of water gagings for the first time and decocts 2 hours; Add for the second time 8 times of water gagings and decocted 1 hour, collecting decoction filters; Filtrating is concentrated into 50 ℃ of heat and surveys relative density 1.30-1.35, and is subsequent use;
3) with powder 1) adding extractum 2) in, fully stirring, drying under reduced pressure is ground into fine powder, and the softgel shell of packing into adds starch and processes capsule, or adds starch 200g, dextrin 40g, Pulvis Talci 45g makes wetting agent with an amount of 70% ethanol, granulates, dries, and is pressed into tablet.
Embodiment 4
1, Chinese medicine ingredients: Radix Ginseng 110g, Ganoderma 72.5g, Rhizoma Dioscoreae 162.5g, Cortex Acanthopancis 72.5g, Radix Astragali 150g, Rhizoma Atractylodis Macrocephalae 72.5g; Fructus Lycii 120g, Rhizoma Polygonati 120g, Hippocampus 60g, Rhizoma Atractylodis 97.5g, Radix Notoginseng 97.5g, Radix Puerariae 137.5g; Rhizoma Coptidis 137.5g, Radix Rehmanniae Preparata 137.5g, Rhizoma Polygonati Odorati 97.5g, Herba Dendrobii 137.5g, Radix Ophiopogonis 162.5g, Radix Polygoni Multiflori 97.5g; Poria 80g, Rhizoma Anemarrhenae 80g, Rhizoma Gastrodiae 40g, Fructus Schisandrae Chinensis 80g, Herba Epimedii 40g.
2, method for preparing is with embodiment 3.
Embodiment 5
1, Chinese medicine ingredients: Radix Ginseng 110g, Ganoderma 72.5g, Rhizoma Dioscoreae 162.5g, Cortex Acanthopancis 72.5g, Radix Astragali 150g, Rhizoma Atractylodis Macrocephalae 72.5g, Fructus Lycii 120g; Rhizoma Polygonati 120g, Hippocampus 60g, Rhizoma Atractylodis 97.5g, Radix Notoginseng 97.5g, Radix Puerariae 137.5g, Rhizoma Coptidis 137.5g; Radix Rehmanniae Preparata 137.5g, Rhizoma Polygonati Odorati 97.5g, Herba Dendrobii 137.5g, Radix Ophiopogonis 162.5g, Radix Polygoni Multiflori 97.5g, Poria 80g; Rhizoma Anemarrhenae 80g, Rhizoma Gastrodiae 40g, Fructus Schisandrae Chinensis 80g, Herba Epimedii 40g, propolis 50g, Folium Mori 62.5g.Add up to 2475g.
2, method for preparing is with embodiment 2.
Comparative Examples 1: choose all antidiabetic drugs and weight thereof in the embodiment of the invention 5, as a comparison example 1
1, Chinese medicine ingredients: Radix Ginseng 110g, Ganoderma 72.5g, Rhizoma Dioscoreae 162.5g, Cortex Acanthopancis 72.5g, Radix Astragali 150g, Rhizoma Atractylodis Macrocephalae 72.5g; Fructus Lycii 120g, Rhizoma Polygonati 120g, Rhizoma Atractylodis 97.5g, Radix Notoginseng 97.5g, Radix Puerariae 137.5g, Rhizoma Coptidis 137.5g; Radix Rehmanniae Preparata 137.5g, Rhizoma Polygonati Odorati 97.5g, Herba Dendrobii 137.5g, Radix Ophiopogonis 162.5g, Poria 80g, Rhizoma Anemarrhenae 80g; Fructus Schisandrae Chinensis 80g, propolis 50g, Folium Mori 62.5g adds up to 2237.5g, accounts for 90.4% of embodiment 5.
2, method for preparing is with embodiment 2.
Comparative Examples 2: choose all depressor and weight thereof in the embodiment of the invention 5, as a comparison example
1, Chinese medicine ingredients: Radix Ginseng 110g, Cortex Acanthopancis 72.5g, Radix Astragali 150g, Fructus Lycii 120g, Hippocampus 60g, Radix Puerariae 137.5g, Herba Dendrobii 137.5g, Rhizoma Gastrodiae 40g, Fructus Schisandrae Chinensis 80g, Herba Epimedii 40g, Folium Mori 62.5g adds up to 1010g, accounts for 41.2% of embodiment 5 gross weights.
2, method for preparing is with embodiment 2.
Chinese medicine compound to the foregoing description 1-5 and Comparative Examples 1,2 preparations is carried out effect experiment, and test method and result are following:
Experimental example 1: blood sugar lowering experiment
1, laboratory animal: the Wistar rat, male, body weight 120-140g, 200.
2, the Chinese medicine of experiment medicine: embodiment of the invention 1-5 preparation, No. 1,2,3,4,5, the blood pressure lowering of called after blood sugar lowering respectively; Wherein the medicine of positive controls is a Comparative Examples 1, is the medicine of all blood sugar reducing functions among the embodiment 5, account for embodiment 5 content 90.4%.Dosage is in the crude drug amount.
3, test method:
1) preparation of high heat feedstuff (composition of every 5kg): normal feedstuff 73%, Adeps Sus domestica 10%, white sugar 15%, cholesterol 2%.
2) type 2 diabetes mellitus model method for preparing is with reference to " Xinjiang medical science " 2009 the 39th volumes, " hyperpyrexia feedstuff and STZ bring out the foundation of type 2 diabetes mellitus animal mould " that Zhu Huhu etc. deliver.
(Streptozotocin STZ) with fresh 2% the solution that is configured to of the aseptic citric acid-sodium citrate buffer of 0.1mol/L, regulates pH value to 4.5, filtration sterilization with streptozotocin;
8 Wistar rats of picked at random are as the normal control group, and promptly A organizes, and all the other rats are adopted the method for lists of references; Feed with the hyperpyrexia feedstuff while lumbar injection STZ 30mg/kg, fasting after 7 days; The next morning is gathered tail blood; Measure fasting glucose, the rat that blood glucose value surpasses 16.7mmol/L is the diabetes model Mus, altogether 118 of diabetes models.
4, divide into groups:
The people intends and uses dosage to be 1.5g/60kgBW day, and concrete dosage is designed to 1.25g/kgBW, is equivalent to the people and intends 50 times with dosage, and the consumption of rat is converted according to following dosage.
Diabetes model is divided into (10 of model control group (9), positive controls (10, Comparative Examples 1, dosage is with 1.4g), No. 1 low dose group of blood sugar lowering blood pressure lowering at random; Dosage 1.0g), dose groups (10, dosage is 1.5g), No. 1 high dose group of blood sugar lowering blood pressure lowering (10, dosage is 2.0g) in No. 1, the blood sugar lowering blood pressure lowering; (10 of No. 2 groups of blood sugar lowering blood pressure lowering; Dosage 1.5g), No. 3 groups of blood sugar lowering blood pressure lowering (10, dosage is 1.5g), No. 4 low dose group of blood sugar lowering blood pressure lowering (10, dosage is 1.0g); Dose groups is (10 in No. 4, the blood sugar lowering blood pressure lowering; Dosage is 1.5g), No. 5 groups of No. 4 high dose group of blood sugar lowering blood pressure lowering (10, dosage is 2.0g) and blood sugar lowering blood pressure lowering (10, dosage is 1.5g).
Normal control group and model control group are irritated stomach with the water for injection of 1.5ml, and the normal control group is fed with normal diet, and other except that the normal control group are respectively organized still and fed with the hyperpyrexia feedstuff every day, and lumbar injection STZ 30mg/kg.
Before administration, the 1st, 2,3 weeks were collected arteria caudalis blood after the administration, detected blood glucose value, and administration is after 28 days; Collect urine, detect the urine protein value, extract eyeball and get blood survey blood glucose and NO; Put to death rat simultaneously and collect pancreatic tissue, propose fat and process section, microscopically is observed.
5, statistical analysis
The data of this experiment all adopt SPSS 11.0 statistical softwares to carry out Treatment Analysis, and each assembly relatively adopts the t check.
6, result
6.1 overview
The normal control group, flexibly movable, hair luster; It is uninteresting that model group agent and all the other are respectively organized hair, lethargy.Test after 28 days, the hair of the high dose group of each blood sugar lowering blood pressure lowering is light gradually.
When testing 14 days, dead 1 rat of model control group was tested dead 2 26 days.
6.2 the variation of blood glucose value (seeing table 1)
In statistic processes, because occur rats death in the experimentation, the blood glucose value after 14 days is the average blood sugar value of residue rat.
Table 1: blood glucose value (mmol/L)
Compare with the normal control group,
※ ※P＜0.01; Compare with model control group,
△P＜0.05,
△ △P＜0.01; Compare with positive controls,
P＜0.05,
P＜0.01
The result shows:
Compare with the normal control group, the blood glucose of model group significantly increases (p＜0.01);
With model group of the same period relatively, positive controls and blood sugar lowering blood pressure lowering compound recipe be blood sugar lowering stably all, after injecting a week, blood glucose value obviously improves (p＜0.05); After two weeks of injection, each organizes blood glucose all be significantly improved (p＜0.01);
With positive controls is that all Chinese medicine composition with hypoglycemic effect are compared among the embodiment 5, irritates stomach after 1 week, no significant difference; After irritating 2 weeks of stomach, 3 weeks, 4 weeks, remove No. 1, blood sugar lowering blood pressure lowering and No. 4 low dose group, all the other are respectively organized all has significant difference (p＜0.01); Irritate stomach after 4 weeks, No. 1, blood sugar lowering blood pressure lowering and No. 4 low dose group have notable difference (p＜0.05).
6.3 urine protein value (table 2)
Table 2: urine protein and NO value
Compare with the normal control group,
※ ※P＜0.01; Compare with model control group,
△P＜0.05,
△ △P＜0.01; Compare with positive controls,
P＜0.05,
P＜0.01;
The result shows:
1) urine protein:
Compare with the normal control group, the urine protein of model group significantly increases (p＜0.01);
With model group relatively, positive controls and each blood sugar lowering blood pressure lowering group be significantly improved (p＜0.01);
With positive controls is that all Chinese medicine composition with hypoglycemic effect are compared among the embodiment 5, and except that No. 1, blood sugar lowering blood pressure lowering and No. 4 low dose group, there were significant differences (p＜0.01) for all the other each groups.
2)NO：
Compare with the normal control group, the urine protein of model group significantly increases (p＜0.01);
With model group relatively, No. 1, blood sugar lowering blood pressure lowering and No. 4 low dose group have clear improvement (p＜0.05); Positive controls and each blood sugar lowering blood pressure lowering group all be significantly improved (p＜0.01);
With positive controls is that all Chinese medicine composition with hypoglycemic effect are compared among the embodiment 5, and except that No. 1, blood sugar lowering blood pressure lowering and No. 4 low dose group, there were significant differences (p＜0.01) for all the other each groups.
Experimental example 2: blood pressure lowering experiment
1, diagnostic criteria: World Health Organization (WHO) worked out in 1978, after promptly 3 inspections are examined, was divided into normal arterial pressure, borderline hypertension and diagnosis hypertension by the height of pressure value.
1) normal arterial pressure: systolic pressure 18.7kPa (140mmHg) or below, diastolic pressure 12.0kPa (90mmHg) or below, and non-hypotensive should be regarded as normal arterial pressure.
2) borderline hypertension: systolic pressure 18.8-21.2kPa (141-159mmHg) and diastolic pressure between 12.1-12.5kPa (91-95mmHg) person for being.
3) make a definite diagnosis hypertension: systolic pressure meets or exceeds 21.3kPa (160mmHg) and diastolic pressure meets or exceeds 12.7kPa (95mm Hg) person for being.
Its definition is: do not using under the situation of antihypertensive drug systolic pressure >=140 millimetress of mercury, diastolic pressure >=90 millimetress of mercury; Previously history of hypertension is arranged, using antihypertensive drug at present,, also should be diagnosed as hypertension though existing blood pressure does not reach above-mentioned level.
2, include patient's standard: systolic pressure＞160mmHg, the patient of diastolic pressure＞95mmHg.
3, the Chinese medicine composition of experiment medicine: embodiment of the invention 1-5 preparation, the blood pressure lowering of called after blood sugar lowering is 1-5 number respectively; Wherein the medicine of positive controls is the medicine of Comparative Examples 2 preparation, is made up of all medicines with hypotensive effect among the embodiment 5, account for embodiment 5 percentage by weight 41.2%, the dosage of use is in the crude drug amount.
4, test method:
Include male patient 49 people altogether, female patient 48 people are divided into positive controls (10 people at random; Comparative Examples 2, dosage are 0.8g), in No. 1, No. 1 low dose group of blood sugar lowering blood pressure lowering (10 people, dosage is 1.0g), blood sugar lowering blood pressure lowering dose groups (10 go into; Dosage is 1.5g), No. 1 high dose group of blood sugar lowering blood pressure lowering (9 people, dosage is 2.0g), No. 2, blood sugar lowering blood pressure lowering group (10 people; Dosage is 1.5g), dose groups (10 people in No. 4, No. 3, blood sugar lowering blood pressure lowering group (10 people, dosage is 1.5g), No. 4 low dose group of blood sugar lowering blood pressure lowering (9 people, dosage is 1.0g), the blood sugar lowering blood pressure lowering; Dosage is 1.5g), No. 5 groups of No. 4 high dose group of blood sugar lowering blood pressure lowering (9 people, dosage is 2.0g) and blood sugar lowering blood pressure lowering (10 people, dosage is 1.5g).
Taking this prescription medicine front and back through 4 groups of patients of follow-up observation of curative effect, conversion hemoglobin, blood pressure situation see the following form:
Table 3: blood pressure information slip
With comparison before the administration,
※P＜0.05,
※ ※P＜0.01; Compare with positive controls,
△P＜0.05,
△ △P＜0.01;
5, the result shows:
5.1 hemoglobin:
With compare before the treatment, the hemoglobin of positive controls, No. 1 low dose group of reducing pressure and sugar, No. 4 low dose group of blood sugar lowering blood pressure lowering obviously reduces (p＜0.05), hemoglobin of all the other each group significantly reduce (p＜0.01);
Compare with positive controls, No. 1, blood sugar lowering blood pressure lowering and No. 4 low dose group do not have notable difference (p＞0.05); No. 1 high dose group of blood sugar lowering blood pressure lowering and No. 4 high dose group have notable difference (p＜0.05), and there were significant differences (p＜0.01) for all the other each groups;
5.2 systolic pressure
With compare before the treatment, each group all has a significant hypotensive effect (p＜0.01);
Compare with positive controls, No. 1 low dosage of blood sugar lowering blood pressure lowering does not have notable difference (p＞0.05); Dose groups and No. 4 low dose group of blood sugar lowering blood pressure lowering have notable difference (p＜0.05) in No. 1, the blood sugar lowering blood pressure lowering, and there were significant differences (p＜0.01) for all the other each groups;
5.3 diastolic pressure
With compare before the treatment, positive controls, No. 1 low dose group of blood sugar lowering blood pressure lowering and No. 4 low dose group have tangible hypotensive effect (p＜0.05), all the other each group has significant hypotensive effect (p＜0.01);
Compare with positive controls, No. 1 low dosage of blood sugar lowering blood pressure lowering and No. 4 low dose group do not have notable difference (p＞0.05); There were significant differences (p＜0.01) for No. 1 high dose group of blood sugar lowering blood pressure lowering and No. 4 high dose group, and all the other each groups have notable difference (p＜0.05);
Conclusion: compare with the combination of all antidiabetic drugs in the blood sugar lowering Chinese hypotensor compositions of the present invention, the combination of all depressor, the Chinese medicine composition better effects if of blood sugar lowering blood pressure lowering of the present invention explains that Chinese medicine composition of the present invention has synergy.
Though, used general explanation, the specific embodiment and test in the preceding text, the present invention has been done detailed description, on basis of the present invention, can to some modifications of do or improvement, this will be apparent to those skilled in the art.Therefore, these modifications or the improvement on the basis of not departing from spirit of the present invention, made all belong to the scope that requirement of the present invention is protected.
Claims (9)
1. the Chinese medicine composition of a blood sugar lowering blood pressure lowering is characterized in that, this Chinese medicine composition is processed by following parts by weight of Chinese traditional medicine: Radix Ginseng 30-50 part, Ganoderma 20-40 part, Rhizoma Dioscoreae 50-80 part; Cortex Acanthopancis 20-40 part, Radix Astragali 45-75 part, Rhizoma Atractylodis Macrocephalae 60-100 part, Fructus Lycii 35-60 part, Rhizoma Polygonati 35-60 part; Hippocampus 15-40 part, Rhizoma Atractylodis 25-55 part, Radix Notoginseng 25-55 part, Radix Puerariae 40-70 part, Rhizoma Coptidis 40-70 part; Radix Rehmanniae Preparata 40-70 part, Rhizoma Polygonati Odorati 25-55 part, Herba Dendrobii 40-70 part, Radix Ophiopogonis 50-80 part, Radix Polygoni Multiflori 25-55 part; Poria 20-45 part, Rhizoma Anemarrhenae 20-45 part, Rhizoma Gastrodiae 10-22 part, Fructus Schisandrae Chinensis 20-45 part and Herba Epimedii 10-22 part.
2. Chinese medicine composition according to claim 1 is characterized in that, this Chinese medicine composition is processed by following parts by weight of Chinese traditional medicine: Radix Ginseng 40-50 part, Ganoderma 25-30 part, Rhizoma Dioscoreae 60-70 part; Cortex Acanthopancis 25-35 part, Radix Astragali 55-65 part, Rhizoma Atractylodis Macrocephalae 70-90 part, Fructus Lycii 40-55 part, Rhizoma Polygonati 40-55 part; Hippocampus 20-30 part, Rhizoma Atractylodis 30-50 part, Radix Notoginseng 30-50 part, Radix Puerariae 50-60 part, Rhizoma Coptidis 50-60 part; Radix Rehmanniae Preparata 50-60 part, Rhizoma Polygonati Odorati 30-50 part, Herba Dendrobii 50-60 part, Radix Ophiopogonis 60-70 part, Radix Polygoni Multiflori 30-50 part; Poria 25-35 part, Rhizoma Anemarrhenae 25-35 part, Rhizoma Gastrodiae 15-20 part, Fructus Schisandrae Chinensis 25-35 part and Herba Epimedii 15-20 part.
3. the Chinese medicine composition of a blood sugar lowering blood pressure lowering, it is characterized in that: this Chinese medicine composition is processed by following parts by weight of Chinese traditional medicine: 44 parts of Radix Ginsengs, 29 parts of Ganodermas, 65 parts of Rhizoma Dioscoreaes, 29 parts of Cortex Acanthopanciss; 60 parts of the Radixs Astragali, 29 parts of the Rhizoma Atractylodis Macrocephalaes, 48 parts of Fructus Lycii, 48 parts of Rhizoma Polygonatis, 24 parts of Hippocampus; 39 parts of Rhizoma Atractylodis, 39 parts of Radix Notoginseng, 55 parts of Radix Puerariaes, 55 parts of Rhizoma Coptidis, 55 parts of Radix Rehmanniae Preparata; 39 parts of Rhizoma Polygonati Odorati, 55 parts of Herba Dendrobiis, 65 parts of Radix Ophiopogonis, 39 parts of Radix Polygoni Multiflori, 32 parts in Poria; 32 parts of the Rhizoma Anemarrhenaes, 16 parts in Rhizoma Gastrodiae, 32 parts of Fructus Schisandrae Chinensis, 16 parts of Herba Epimedii, 25 parts on 20 parts of propolis and Folium Mori.
4. the Chinese medicine composition of a blood sugar lowering blood pressure lowering, it is characterized in that: this Chinese medicine composition is processed by following parts by weight of Chinese traditional medicine: Radix Ginseng 140g, Ganoderma 90g, Rhizoma Dioscoreae 200g, Cortex Acanthopancis 90g, Radix Astragali 190g; Rhizoma Atractylodis Macrocephalae 250g, Fructus Lycii 150g, Rhizoma Polygonati 150g, Hippocampus 75g, Rhizoma Atractylodis 130g; Radix Notoginseng 130g, Radix Puerariae 180g, Rhizoma Coptidis 180g, Radix Rehmanniae Preparata 180g, Rhizoma Polygonati Odorati 130g; Herba Dendrobii 130g, Radix Ophiopogonis 200g, Radix Polygoni Multiflori 130g, Poria 100g, Rhizoma Anemarrhenae 100g; Rhizoma Gastrodiae 50g, Fructus Schisandrae Chinensis 100g, Herba Epimedii 50g, propolis 56g, Folium Mori 70g.
5. a method for preparing each described Chinese medicine composition of claim 1-3 is characterized in that, may further comprise the steps:
1) takes by weighing above-mentioned 23 flavor Chinese crude drugs, use the clear water cleaning, drying;
2) Radix Ginseng, Ganoderma, the Radix Astragali, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae, Radix Puerariae Six-element medicated powder are broken into smalls, sieve;
3) with remaining 17 flavor Chinese medicine decocte with water secondary, collecting decoction filters, and filtrating is condensed into extractum;
4) with extractum and step 2 in the step 3)) in the powder mixing, promptly get.
6. a method for preparing the described Chinese medicine composition of claim 4 is characterized in that, may further comprise the steps:
1) takes by weighing above-mentioned 25 flavor Chinese crude drugs, use the clear water cleaning, drying;
2) Radix Ginseng, Ganoderma, the Radix Astragali, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae, Radix Puerariae Six-element medicated powder are broken into smalls, sieve;
3) with remaining 19 flavor Chinese medicine decocte with water secondary, collecting decoction filters, and filtrating is condensed into extractum, adds step 2) in powder, mixing promptly gets.
7. method according to claim 6 is characterized in that, may further comprise the steps:
1) takes by weighing above-mentioned 25 flavor Chinese crude drugs according to proportioning, wash 4-5 time, put into dehydrator 70-90 ℃ of oven dry 20-30 minute with clear water;
2) Radix Ginseng, Ganoderma, the Radix Astragali, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae, Radix Puerariae Six-element medicated powder are broken into smalls, cross 100 mesh sieves;
3) with remaining 19 flavor Chinese medicine decocte with water secondary, add 10 times of water gagings for the first time and decocted 2 hours, add 8 times of water gagings the second time and decocted 1 hour, collecting decoction filters, and it is the extractum of 1.30-1.35 that filtrating is concentrated into 50 ℃ of heat survey relative densities;
4) with extractum and step 2) in the powder mixing, promptly get.
8. the preparation that contains each described Chinese medicine composition of claim 1-4, said preparation is made up of active component and pharmaceutically acceptable carrier or diluent.
9. preparation according to claim 8, said preparation are solid preparation or liquid preparation.
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