CN102083494B - 用于治疗眼科疾病的酮替芬透皮药物递送系统 - Google Patents

用于治疗眼科疾病的酮替芬透皮药物递送系统 Download PDF

Info

Publication number
CN102083494B
CN102083494B CN2008801296458A CN200880129645A CN102083494B CN 102083494 B CN102083494 B CN 102083494B CN 2008801296458 A CN2008801296458 A CN 2008801296458A CN 200880129645 A CN200880129645 A CN 200880129645A CN 102083494 B CN102083494 B CN 102083494B
Authority
CN
China
Prior art keywords
drug delivery
transdermal drug
delivery systems
ketotifen
pressure sensitive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2008801296458A
Other languages
English (en)
Chinese (zh)
Other versions
CN102083494A (zh
Inventor
山地正博
A·蓬皮拉帕特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teikoku Pharma USA Inc
Original Assignee
Teikoku Pharma USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Pharma USA Inc filed Critical Teikoku Pharma USA Inc
Publication of CN102083494A publication Critical patent/CN102083494A/zh
Application granted granted Critical
Publication of CN102083494B publication Critical patent/CN102083494B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00544—Plasters form or structure
    • A61F2013/00646—Medication patches, e.g. transcutaneous
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00655—Plasters adhesive
    • A61F2013/00659—Plasters adhesive polymeric base
    • A61F2013/00663—Plasters adhesive polymeric base acrylic

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2008801296458A 2008-05-30 2008-10-08 用于治疗眼科疾病的酮替芬透皮药物递送系统 Expired - Fee Related CN102083494B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5774808P 2008-05-30 2008-05-30
US61/057,748 2008-05-30
US12/236,392 US20090297590A1 (en) 2008-05-30 2008-09-23 Ketotifen transdermal drug delivery systems and methods for treating ophthalmic disease
US12/236,392 2008-09-23
PCT/US2008/079211 WO2009145801A1 (en) 2008-05-30 2008-10-08 Ketotifen transdermal drug delivery systems and methods for treating ophthalmic disease

Publications (2)

Publication Number Publication Date
CN102083494A CN102083494A (zh) 2011-06-01
CN102083494B true CN102083494B (zh) 2013-11-13

Family

ID=41377403

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801296458A Expired - Fee Related CN102083494B (zh) 2008-05-30 2008-10-08 用于治疗眼科疾病的酮替芬透皮药物递送系统

Country Status (9)

Country Link
US (1) US20090297590A1 (enExample)
EP (1) EP2296748B1 (enExample)
JP (1) JP2011523650A (enExample)
KR (1) KR20110019382A (enExample)
CN (1) CN102083494B (enExample)
AR (1) AR070031A1 (enExample)
ES (1) ES2458627T3 (enExample)
TW (1) TW200948401A (enExample)
WO (1) WO2009145801A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5241714B2 (ja) 2006-07-07 2013-07-17 プロテウス デジタル ヘルス， インコーポレイテッド スマートな非経口送達システム
EP2211974A4 (en) 2007-10-25 2013-02-27 Proteus Digital Health Inc INFORMATION SYSTEM FOR LIQUID FLOW CHANNEL
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
AU2011210648B2 (en) 2010-02-01 2014-10-16 Otsuka Pharmaceutical Co., Ltd. Data gathering system
MY169700A (en) 2010-02-01 2019-05-13 Proteus Digital Health Inc Data gathering system
US20130060209A1 (en) * 2011-05-12 2013-03-07 Parker Campbell Tyler Athletic Tape
US8900626B2 (en) 2011-06-20 2014-12-02 Senju Usa, Inc. Transdermal drug delivery system and method of using the same
WO2014028396A2 (en) * 2012-08-13 2014-02-20 Hicken Matthew Therapeutic elastic tape
CA2894696A1 (en) * 2012-12-21 2014-06-26 Teikoku Pharma Usa, Inc. Compositions and methods for transdermal delivery of hormones and other medicinal agents
WO2016124601A1 (en) * 2015-02-02 2016-08-11 Santen Pharmaceutical Co., Ltd Polyaphrons and palpebral administration thereof
USD890936S1 (en) 2018-05-25 2020-07-21 Blacktop Plus, Llc Therapeutic elastic sports tape

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020012695A1 (en) * 2000-06-16 2002-01-31 Lee Wan S. Transdermal preparation containing hydrophilic or salt-form drug
US20060036220A1 (en) * 2003-01-22 2006-02-16 Kohji Kawahara Percutaneous absorption preparation for treating ophthalmic disease, use thereof and method for migration of ophthalmic remedy into topical tissue in eye
WO2006114868A1 (ja) * 2005-04-20 2006-11-02 Nichiban Co., Ltd. 経皮吸収製剤
US20060257460A1 (en) * 2005-05-13 2006-11-16 Jansen Rolf R Multilayer drug delivery system with barrier against antagonist exposure

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2512805B2 (ja) * 1989-07-14 1996-07-03 積水化学工業株式会社 ケトチフェン経皮吸収製剤
JP2879362B2 (ja) * 1990-08-07 1999-04-05 富山化学工業株式会社 ケトチフェンのプラスター剤
JP4205778B2 (ja) * 1998-04-17 2009-01-07 久光製薬株式会社 貼付製剤
US20030104041A1 (en) * 1999-12-16 2003-06-05 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
JP4213432B2 (ja) * 2002-08-28 2009-01-21 久光製薬株式会社 貼付剤
JPWO2005115355A1 (ja) * 2004-05-28 2008-03-27 久光製薬株式会社 貼付製剤
WO2006036899A2 (en) * 2004-09-27 2006-04-06 Corium International, Inc. Transdermal systems for the delivery of estrogens and progestins
JP5075334B2 (ja) * 2004-11-22 2012-11-21 久光製薬株式会社 薬物含有貼付剤
KR100835074B1 (ko) * 2006-09-27 2008-06-03 조선대학교산학협력단 멜록시캄 경피 흡수제 조성물 및 그의 제조 방법

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020012695A1 (en) * 2000-06-16 2002-01-31 Lee Wan S. Transdermal preparation containing hydrophilic or salt-form drug
US20060036220A1 (en) * 2003-01-22 2006-02-16 Kohji Kawahara Percutaneous absorption preparation for treating ophthalmic disease, use thereof and method for migration of ophthalmic remedy into topical tissue in eye
WO2006114868A1 (ja) * 2005-04-20 2006-11-02 Nichiban Co., Ltd. 経皮吸収製剤
US20060257460A1 (en) * 2005-05-13 2006-11-16 Jansen Rolf R Multilayer drug delivery system with barrier against antagonist exposure

Also Published As

Publication number Publication date
WO2009145801A1 (en) 2009-12-03
JP2011523650A (ja) 2011-08-18
CN102083494A (zh) 2011-06-01
KR20110019382A (ko) 2011-02-25
EP2296748A4 (en) 2011-09-28
EP2296748B1 (en) 2014-04-02
EP2296748A1 (en) 2011-03-23
AR070031A1 (es) 2010-03-10
US20090297590A1 (en) 2009-12-03
TW200948401A (en) 2009-12-01
ES2458627T3 (es) 2014-05-06

Similar Documents

Publication Publication Date Title
CN102083494A (zh) 用于治疗眼科疾病的酮替芬透皮药物递送系统和方法
JP4629578B2 (ja) 眼疾患治療用経皮吸収型製剤
CN103476404B (zh) 包含活性剂层和活性剂转化层的透皮组合物
US20040028726A1 (en) Transdermal systems for the delivery of clonidine
US9700522B2 (en) Transdermal patch and method for delivery of vitamin B12
CN102630160A (zh) 透皮递送系统、其制备方法以及使用所述系统的透皮递送方法
US20070264319A1 (en) Transdermal Antiemesis Delivery System, Method and Composition Therefor
JP2017014268A (ja) フェンタニルを投与するための経皮的張り付け剤
CN106659702A (zh) 透皮递送体系
US20140242151A1 (en) Adhesive skin patch
JPH0667835B2 (ja) 医薬組成物
US20100178307A1 (en) Transdermal anti-dementia active agent formulations and methods for using the same
CN104043127A (zh) 用于增强药物的经皮吸收的组合物和贴片制剂
JP4001927B2 (ja) 物理的特性の改善されたポリアクリレートマトリックスを有する経皮吸収または局所プラスターシステム
JP7183041B2 (ja) 経皮薬物送達システムおよびその使用方法
JP2009173679A (ja) 部分的ドーパミン−ｄ２作用薬の投与用の経皮治療吸収システム
WO2020093906A1 (zh) 含有布洛芬或其结构类似物的多层经皮给药系统
JP5192722B2 (ja) 外用貼付剤
Kharia et al. Overview of Transdermal Medicated Patches with its research updates in preceding years.
JP5512910B2 (ja) ツロブテロール含有経皮吸収製剤およびこれを使用する貼付剤
CN108289859A (zh) 用于透皮给药的系统和方法
JP2007520480A (ja) 少なくとも一つの脂肪酸を含むジヒドロピリジンタイプのカルシウムアンタゴニスト用の経皮的デリバリー器具
JP3098095B2 (ja) 透湿性支持体を用いた貼付剤
WO2018199018A1 (ja) 経皮吸収型製剤およびその製造方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20131113

Termination date: 20141008

EXPY Termination of patent right or utility model