CN102078520B - Chinese medicinal preparation for treating nervous headache and preparation method thereof - Google Patents

Abstract

The invention relates to a Chinese medicinal preparation for treating nervous headache, which comprises the following raw material medicines: Chinese angelica, bupleurum, root of red-rooted salvia, peach seed, manchurian wildginger, white paeony root, largehead atractylodes rhizome, incised notopterygium rhizome, szechuan lovage rhizome, myrrh, polygalae root, platycladi seed, silktree albizzia bark, tall gastrodia tuber, gambir plant and eucommia bark, wherein for patients who suffer from yin deficiency and yang excess and wind-evil invasion, weeping forsythia, cassia seed, baical skullcap root and dwarf lilyturf tuber are added into the raw material medicines; for patients who suffer from dizziness, vexation, xerostomia and bitterness in mouth and upward invasion of liver-fire, angelica dahurica, common selfheal fruit-spike, prepared tuber of multiflower knotweed and gardenia jasminoides are added into the raw material medicines; and for patients who suffer from insomnia, dreaminess, deficiency of qi and blood stasis, raw rehmannia root, astragalus, spina date seed, curcuma aromatica and tuber feeceflower stem are added into the raw material medicines. In the Chinese medicinal preparation, the selected raw material medicines are mainly used for dispelling wind and eliminating cold, eliminating blood stasis and removing obstruction in channels, invigorating blood circulation, promoting qi and relieving pain, and can address both symptoms and root causes based on the theory with syndrome differentiation. 'Pain onsets when obstructed and goes when passable', so a method for removing obstruction in channels to relieve pain is mainly adopted on treatment. By the Chinese medicinal preparation, the angiokinesis function restores to be normal, branch artery spasm is removed, the blood supply of local tissue restores to be normal, and microcirculation is improved, so that channels and collaterals are dredged to fulfill the aim of 'pain goes when passable'.

Description

A kind of Chinese medicine preparation of treating nervous headache and preparation method thereof

Technical field

The present invention relates to contain medicinal preparation that derives from plant, animal or raw mineral materials and preparation method thereof, particularly a kind of Chinese medicine preparation of treating nervous headache and preparation method thereof.

Background technology

Nervous headache mainly is meant tension headache, functional headache and angioneurotic headache, how to be caused by psychentonia, anger, and cardinal symptom is the vexed pain of the head of persistence, constriction, sense of heaviness, and the patient's private prosecution that has is that head has " lock ring " sense.Tired or depressed and bring out or increase the weight of in overwork, one side or bilateral head pulsation jumping pain, distending pain or twinge during outbreak, with feel sick, vomiting, insomnia, symptom such as fidgety, it has intermittent history of repeated attack.Angioneurotic headache, headache character have jumping pain, twinge, lancinating pain, beat appearance pain, distending pain etc., weight person's intense splitting headache.Most of patient is with symptoms such as giddy, insomnia, vexed, hypomnesis.Weight person also with feel sick, pain is taken out in vomiting, eyes, shed tears, blurred vision.Patient's a few days that has or several months outbreak 1 time, 1 day of having outbreak 2～3 times, very then pain is uninterrupted.Fatigue, rage, food maror, long-term insomnia etc. are risk factor.The headache of part female patient is relevant with menstrual cycle.Its pathogenesis still imperfectly understands; The a series of biochemical changes relevant have been found at present with it; Especially the variation of 5-hydroxy tryptamine; So think that primary disease possibly be the vasomotor disturbance property disease due to a kind of human endocrine is lacked of proper care, be that cerebral vasospasm shrinks and expansion causes that blood flow changes and obstacle, near the tissue blood causing becomes silted up and hinders.Therefore Western medicine is used XIBILING JIAONANG, can make the blood vessel of spasm be able to expansion, and blood fortune is delayed and passed unimpeded, and can improve vasomotor dysfunction, but curative effect is often unstable, and cure rate is low, is difficult to remove old complaint.

Headache is a common sympton, does not have specificity and process mostly well, and the headache during like actute infection is alleviated with good the transferring of protopathy.Symptom is the signal of serious disease but some is had a headache, have a headache like the hypertensive arteriosclerosis patient and aggravate suddenly, and when especially the companion vomits, the generation of the vigilant cerebral hemorrhage of palpus.The headache of the cerebral tumor, brain abscess, cerebral trauma etc. like carrying out property aggravation in the course of disease, is often pointed out the state of an illness to increase the weight of or is worsened.Its cause of disease is a lot, one type of headache is wherein arranged with cervical region tenderness, the headache relevant with the cervical nerves irriate, and incidence rate is very high, complicated clinical, and the headache longer duration, treatment is difficulty, draws attention day by day.This kind headache once had been called as " nervous headache ", " nervous vascular Headache ", " neuralgia of greater occipital nerve ", " otoneuralgia " etc. in the past.Thought in the past that this kind headache was that the nerve and the blood vessel of head produces headache under the effect of paathogenic factor; Thereby Therapeutic Method mainly is oral nonsteroidal anti-inflammatory drug, head acupuncture, physical therapy, massage, the injection of head pain spot; Head nerves is done retardance, comprises the retardance of greater occipital nerve or nervus auricularis magnus.But the state of an illness that a considerable amount of patients are arranged does not take a turn for the better or curative effect is not lasting.Form the situation of " patient's headache, the doctor also has a headache ".This clinical status is promoting this type of pathogenetic further investigation of having a headache.

And the traditional Chinese medical science is to this present situation; The hypothesis of the pathogenesis of headache for " nerve-blood vessel-blood " system disorders proposed; And play therapeutical effect through a plurality of target spots that the Chinese medicine number of ways acts on these system's many levels, demonstrated the distinctive feature of Chinese medicine headache.And the traditional Chinese medical science is to this present situation; The hypothesis of the pathogenesis of headache for " nerve-blood vessel-blood " system disorders proposed; And play therapeutical effect through a plurality of target spots that the Chinese medicine number of ways acts on these system's many levels, demonstrated the distinctive feature of Chinese medicine headache.Treatment to nervous headache; At present; What mostly adopt pain relieving class or antidepressant class is main Western medicine with the symptomatic treatment, or adopts and comprise that acusector moxibustion therapy, neuromuscular electrical stimulating therapy, electroexcitation therapy, meridians lead to bring under control and treat and " the comprehensive physiotherapy " of massage treatment etc.Adopt western medicine, it is cured the symptoms, not the disease, though the state of an illness can be alleviated, still also often shows effect repeatedly, even the back something lost phenomenon of pain relieving class medicine in addiction also can occur taking.Adopt " comprehensive naturopathy ", its course of treatment is long, the therapy general effect is not quite remarkable.

Summary of the invention

Technical problem to be solved by this invention is, a kind of Chinese medicine preparation of treating nervous headache and preparation method thereof is provided, strong, the alleviation headache rapidly of Chinese medicine preparation targeting property of the present invention; Blood circulation promoting and blood stasis dispelling; Treating both the principal and secondary aspects of a disease, and processing technology is easy, the little and convenient drug administration of toxic and side effects; Medicament is easy to make, and is with low cost.Chinese medicine preparation of the present invention, selected blood circulation promoting and blood stasis dispelling, the Chinese crude drug of the different property of medicine of removing obstruction for relieving pain has carried out the science compatibility; Can reach the effect of ideal treatment nervous headache, and safety, toxic and side effects is little, and preparation is simple; The through focus of ability, healing time is short, cures the difficult recurrence in back.

For solving the problems of the technologies described above, the present invention provides a kind of Chinese medicine preparation of treating nervous headache, and the ratio of weight and number of various crude drug can be 10～20 parts of Radix Angelicae Sinensis, 10～20 parts of Radix Bupleuri in the said preparation; 10～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts in Semen Persicae, 10～20 parts of Herba Asaris, 10～20 parts of the Radix Paeoniae Albas; 10～20 parts of the Rhizoma Atractylodis Macrocephalaes, 10～20 parts of Rhizoma Et Radix Notopterygiis, 10～20 parts of Rhizoma Chuanxiongs, 10～20 parts of Myrrhas; 10～20 parts of Radix Polygalaes, 10～20 parts of Semen Platycladi, 10～20 parts of Cortex Albiziaes; 10～20 parts in Rhizoma Gastrodiae, 10～20 parts of Ramulus Uncariae Cum Uncis, 10～20 parts of the Cortexs Eucommiae.

The Chinese medicine preparation of said treatment nervous headache when disease is seen hyperactivity of YANG due to deficiency of YIN, can add 10～20 parts of Fructus Forsythiaes, 10～20 parts of Semen Cassiaes, 10～20 parts of Radix Scutellariaes, 10～20 parts of Radix Ophiopogonis during the ailment said due to cold or exposure invasion.

The Chinese medicine preparation of said treatment nervous headache, when dizzy, vexed, the dry mouth with bitter taste of companion, liver-fire superinverse person can add 10～20 parts of the Radixs Angelicae Dahuricae, 10～20 parts of Spica Prunellaes, 10～20 parts of Radix Polygoni Multiflori Preparata, 10～20 parts of Fructus Gardeniaes.

The Chinese medicine preparation of said treatment nervous headache, when companion's insomnia and dreamful sleep, gas loses blood stasis person can add 10～20 parts of Radix Rehmanniae, 10～20 parts of the Radixs Astragali, 10～20 parts of Semen Ziziphi Spinosaes, 10～20 parts of Radix Curcumaes, 10～20 parts of Caulis Polygoni Multiflori.

The Chinese medicine preparation of said treatment nervous headache, its dosage form can be preferably: honey refines pill, tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, sucks agent, granule, electuary, pill, powder, sublimed preparation, solution, injection, plaster and syrup.

For solving the problems of the technologies described above, the present invention also provides a kind of method for preparing of treating the Chinese medicine preparation of nervous headache, when said preparation formulation is that the method for preparing of capsule can comprise:

A gets crude drug and adds water extraction 2 times, becomes the extractum shape, is component 1;

It is the extractum shape that the b medicinal residues add the ethanol thickening filtration, is component 2;

C mixes pulverizing with component 1 and component 2, and it is an amount of to add dextrin, mixing, fill capsule.

Among the said step a, can get crude drug and add water logging bubble 1-2 hour that 5-10 doubly measures, extract 2 times; Heating extraction 1-2 hour, be concentrated into the extractum shape, become component 1.

Among the said step b, can medicinal residues be added the 60-90% soak with ethanol 1-2 hour, extract twice; Each 0.5-1 hour, merge extractive liquid, filtered; Concentrate, the 80-160 order filters, the 6000-10000 rev/min of supernatant after centrifugal; Through the molecular weight that dams is the ultrafiltration post ultrafiltration of 5000-10000, and ultrafiltrate concentrating under reduced pressure relative density is the extractum of 1.38 (80 ℃), as component 2.

Among the said step c, can component 1 be mixed with component 2 and pulverize, the adding dextrin is an amount of, puts into the hothouse drying, and hot stream temperature is 80 ℃-100 ℃, gets raw material medicated powder, incapsulates patent medicine.

For solving the problems of the technologies described above; The present invention also provides a kind of method for preparing of treating the Chinese medicine preparation of nervous headache; When the dosage form of the said preparation method for preparing for honey refining pill comprises: earlier said crude drug is ground into coarse powder, further pulverizes again, cross 120 mesh sieves; The fine powder amount that enable pass is crossed 120 mesh sieves reaches 30%, and the fine powder of collecting through 120 mesh sieves gets fine powder a; Can not drop into multi-function extractor through the coarse powder of 120 mesh sieves again and extract twice, and add 8-10 times of water gaging for the first time and decocted 1-2 hour, and add 4-8 times of water gaging for the second time and decocted 1-2 hour, merge decocting liquid twice, and cross and filter filtrating; Heating is concentrated into pasty state, puts into 80 ℃ in baking oven oven dry postcooling, grinds to form fine powder b, with a with call in Mel after b mixes and process the sweet pill that refines.

Chinese medicine preparation of the present invention has suppressing the hyperactive liver pain relieving, regulating qi-flowing for strengthening spleen, spleen reinforcing lung kidney, invigorating the spleen and replenishing QI and blood circulation promoting and blood stasis dispelling, the effect of removing obstruction for relieving pain, and targeting property is strong, alleviate headache rapidly; Blood circulation promoting and blood stasis dispelling, treating both the principal and secondary aspects of a disease, and processing technology is easy; Toxic and side effects is little; And convenient drug administration, medicament is easy to make new drug with low cost.The present invention is a Chinese medicine preparation, selected blood circulation promoting and blood stasis dispelling, and the Chinese crude drug of the different property of medicine of removing obstruction for relieving pain has carried out the science compatibility, can reach the effect of ideal treatment nervous headache.The present invention adopts the Chinese crude drug of the different property of medicine, has carried out the science compatibility, can reach ideal therapeutic effect, and safety, and toxic and side effects is little, and preparation is simple, the focus of going directly, and healing time is short, cures the back and is difficult for recurrence.

The specific embodiment

Motherland's medical science thinks that angioneurotic headache belongs to wind syndrome of head, migraine category.Motherland's medical science is thought, all YANG-meridians meeting into the head, the gas of the clear sun of the vital organs of the human body are annotated in head on all.Wind syndrome of head is many to cause clear YANG failing to ascend by excessive rising of liver-YANG, phlegm and blood stasis, or violates on the turbid pathogen, and YANG-orifices failing to be nourished serve as the disease that mainly shows with head pain.The head painful area is many at a side temporo, volume, socket of the eye, or involves zones such as two temporos, the crown, and for liver channel of foot-Jueyin follows capable part, medication is many starts with from liver.The suitable suppressing the hyperactive liver and subsiding YANG of treatment, promoting blood circulation to remove obstruction in the collateral.The traditional Chinese medical science thinks, nervous headache be in knot wind and cold, obstruction of meridian, qi depression to blood stasis, the straight criminal empties, the blood deficiency passages through which vital energy circulates loses supports, method of treatment is then with expelling wind and cold, disperse blood stasis and dredge collateral, the blood-activating and qi-promoting pain relieving is main.Therefore, control treating both the principal and secondary aspects of a disease when carrying out dialectical executing with utilization Chinese medicine theory.

Headache, dizzy, dizziness are the common clinical symptoms of department of neurology; Numerous disease all can cause headache or dizzy, dizzy; Like vascular headache, migraine; Neurasthenia, craniocerebral trauma, Meniere, vestibule illness and by vertebro-basilar artery insufficiency etc. cause dizzy, dizzy, dizzy and tinnitus, dysaudia and autonomic nervous dysfunction's symptom are often arranged, influence work and daily life when serious.Therefore, the medicine that works out the treatment above-mentioned symptom will bring huge Gospel to a lot of patients.Chinese medicine thinks that head is " confluence of all yang-channels " " mansion of clear sun ", and hands, the three yang channels of foots and liver channel of foot-Jueyin are all up in women's head-ornaments; Governor vessel directly and the brain mansion interrelate; Therefore, various diseases caused by exogenous pathogenic factor and internal injury factor cause the head meridian function not normal, disorder of QI and blood; Obstructed or the brain key of venation loses supports etc., all can cause headache.Angioneurotic headache belongs to headache due to internal injury more, and its morbidity is many because of pathogenic fire derived from stagnation of liver-QI, on disturb sun clearly, the resistance of meridians numbness is obstructed, send out to be headache, the evil stasis of blood with the passing of time, obstruction of collaterals by blood stasis, QI and blood is disorderly contrary, it is difficult to cause the primary disease delay." general rule not bitterly, pain then obstructed " is so should be rule of treatment with the removing obstruction in the collateral to relieve pain in treatment.Adjust orthosympathetic function, make vasomotoricity recover normal, remove the bifurcated artery spasm, make the local organization blood supply recover normal, microcirculation is improved, thereby dredging the meridian makes its " logical and not bitterly ".

Radix Bupleuri, Semen Persicae and Fructus Gardeniae up-down regulating QI can be nursed one's health the liver and gall mechanism of qi in the side, again can the function of spleen and stomach regulating mechanism of qi; Radix Curcumae people blood system is assisted the Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI; Radix Angelicae Sinensis, the Radix Astragali, Radix Paeoniae Alba nourshing blood and promoting blood circulation, blood stasis dispelling, QI and blood dash with, ten thousand diseases are not given birth to, Rhizoma Chuanxiong.Myrrha blood circulation promoting and blood stasis dispelling, removing obstruction for relieving pain, modern medicine study show that drug for invigorating blood circulation and eliminating stasis can promote organism metabolism, improve the cerebral cortex irritability, cooperate the resolving depression medicine of regulating the flow of vital energy, and can improve depressive state.Radix Salviae Miltiorrhizae, the Radix Polygoni Multiflori Preparata nourishing blood to suppress the hyperactive liver prevents to regulate the flow of vital energy and too robs impairing the liver the moon; The yin nourishing of relieving inflammation or internal heat of Radix Scutellariae fire-transformation, Semen Cassiae; Ramulus Uncariae Cum Uncis, the Spica Prunellae the moon that nourishes heart; Semen Ziziphi Spinosae is held back liver-yin, Cortex Albiziae, and Semen Platycladi, Semen Ziziphi Spinosae, Radix Polygalae is calmed the nerves.Rhizoma Gastrodiae, the Cortex Eucommiae is regulated immunity, improves cytoactive, the mediation blood vessels; All medicines share, the merit that common long memorial liver and qi, blood stasis dispelling are calmed the nerves.

Semen Platycladi property is put down sweet in the mouth, the heart, kidney, large intestine channel.The effect of tool tranquilizing by nourishing the heart, loosening bowel to relieve constipation.Control diseases such as palpitation with fear, insomnia, seminal emission, night sweat, constipation, ability tranquilizing by nourishing the heart, loosening bowel to relieve constipation.Be used for restlessness of asrhenia type and insomnia, severe palpitation, dryness of the intestine makes the secret disease that Dengs." medicineization justice ": Semen Platycladi, fragrance passes through the heart, and the body profit is grown blood.Same Poria cum Radix Pini, Semen Ziziphi Spinosae, the Radix Rehmanniae, Radix Ophiopogonis are article clearly in turbid, and it is timid to cure mainly mind void, the palpitation with fear severe palpitation, and color is wan and sallow, the skin pruritus due to dryness, the merit of the blood that all nourishes heart is also.It is all dense to get abnormal smells from the patient again, returns kidney in turbid, and same Radix Rehmanniae Preparata, Carapax et Plastrum Testudinis, Fructus Lycii, Radix Achyranthis Bidentatae for packing bone marrow, cure mainly damage of kidney-YIN, the back severe disease, and sufficient knee joint is weak, night sweat due to yin deficiency, all the dry power of nourishing kidney is also.Sweet in the mouth also can delay liver, and the deficiency of tonifying liver gallbladder is extremely reliable, but the flat power of property is slow, suitable more than uses be wonderful.

The Ramulus Uncariae Cum Uncis another name is big Ramulus Uncariae Cum Uncis, Ramulus Uncariae macrophyllae again.For Maguireothamnus speciosus Ramulus Uncariae Cum Uncis or Uncaria sinensis (Oliv.) Havil. and belong to the buckle branch of various plants together, climb up by holding on to the shape shrub, Gao Keda 10m.Cylindrical or type square column type of stem branch has thin longitudinal grin.Reclinate double hook or single hook are arranged on the joint, the stipule trace is arranged under the hook.Matter is hard, and the stem section has the yellow-white marrow.Stem branch with buckle is used as medicine.In the spring, gather autumn, removes blade, cuts off, and dries.Property is cool in nature, sweet in the mouth.Function heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.Dizzy, dysphoric cold, diarrhea induced by fright tic, pregnant sub-dysentery, vascular hypertension are used to have a headache." detailed outline " carries it: " Ramulus Uncariae Cum Uncis, hands, foot are fainted cloudy medicine also.The foot cloudy main air of fainting, the hands cloudy main fire of fainting, the dizzy fortune of infantile convulsion, liver-wind diseases of fire mutually all, the logical pericardium of Ramulus Uncariae Cum Uncis is in edema with the liver involved, and the quiet fire of wind puts out, and then all diseases are removed certainly." it has the good sedative effect through evidence, Ramulus Uncariae Cum Uncis decoct 0.1 gram/kilogram can produce tangible sedation, but not have tangible syngignoscism to the mouse peritoneal injection.

Fructus Gardeniae is bitter, and is cold.GUIXIN, lung, tri-jiao channel.Be used for calentura heating, vexedly rather do not wait disease.Fructus Gardeniae is kind to expel the heat-evil and relieving restlessness in pathogenic fire purging.At the edema caused by disorder of QI disease initial stage of fever caused by exogenous pathogenic factors, see disease such as heating is arranged, uncomfortable in chest, vexed, available Fructus Gardeniae cooperates Semen Sojae Preparatum, with expelling pathogenic factors from the exterior expel the heat-evil, the relieving restlessness resolving depression.As belong to all excess-heat fire diseases and see diseases such as hyperpyrexia agitation, unconsciousness and delirium, available article are joined pathogenic fire purging such as Cortex Phellodendri and clear pathogen is warm.

Radix Polygalae is bitter, hot, tepor.GUIXIN, kidney, lung meridian.Function cures mainly the Fructus Alpiniae Oxyphyllae of calming the nerves, and eliminates the phlegm detumescence.Be used for the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.Be applied to insomnia and dreamful sleep, severe palpitation, forgetful.These article toil is warm in nature, property is kind lead off sensible, happily gas and mind tranquilizing and the heart calming, can lead to kidney qi and strong will is not forgotten, be restoring normal coordination between the heart and kidney, stable mind, the Fructus Alpiniae Oxyphyllae good merchantable brand of knowledge by force.Cure mainly the diseases such as malaise, insomnia, palpitation with fear of disarmony between the heart and kidney, normal and the same usefulness of medicinal for tranquilizing mind such as Poria cum Radix Pini, Dens Draconis, Cinnabaris are like Radix Polygalae ball (" the Zhang Shi doctor is led to "); Control forgetful card, normal and Radix Ginseng, Poria, the same usefulness of Rhizoma Acori Graminei are loose (" prescriptions worth thousand gold ") as happy, add Poria cum Radix Pini, promptly do not forget to loose (" Standards of Diagnosis and Treatment ") as if Fang Zhongzai." book on Chinese herbal medicine is just ": Radix Polygalae, the wholwe-hearted kidney of merit, so but the relieving palpitation spasmolytic, the peace that exorcises evil spirits dream, Yang strengthening and life essence tonifying, strong will power-assisted.

Radix Bupleuri is bitter, is slightly cold.Return liver, gallbladder meridian.Function is brought down a fever soothing liver-QI, yang invigorating with curing mainly to evacuate.Be used for cold, fever, alternate attack of chill and fever, malaria, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.Be soothing the liver good medicine of fostering the spirit of nobility.

The Semen Ziziphi Spinosae nourishing the liver, mind calming is calmed the nerves, arresting sweating.Control restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility." herbal classic ": main trusted subordinate's cold and heat, pathogens agglomerating gas gathers, painful limbs, arthralgia chiefly caused by damp pathogen." not Lu ": main vexatious insomnia, umbilicus is pain up and down, and blood changes chronic diarrhea, the sweating due to debility excessive thirst, invigorating middle warmer, the liver benefiting gas, hard muscles and bones is helped cloudy gas, makes us fertile strong.Control consumptive disease with restlessness, insomnia is controlled heart and is lost emptyly, and mind is not kept, and is terrified frightened cautious, often how in a trance, is easy to forgetfully, and it is not peaceful to doss, and dream relates to danger, all heart diseases " detailed outline ": Semen Ziziphi Spinosae, and Gan Errun, so ripe insomnia due to insufficiency of the gallbladder-qi with treatment, the card of excessive thirst sweating due to debility; Give birth to treating gallbladder-heat and sleep well.All foot is fainted the moon, few positive medicine also, and moderns specially think heart man medicine, very hide this reason.

Rhizoma Atractylodis Macrocephalae bitter in the mouth, sweet, temperature.Return spleen, stomach warp.Cure mainly invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.Be used for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement." property of medicine opinion " carried it: monarch, and sweet in the mouth, suffering, nontoxic.Can main big migratory arthralgia, diarrhea due to disorder of qi for many years, trusted subordinate's distending pain, the broken dyspepsia that disappears, sputum is removed in appetizing, removes cold and heat, lets out under ending.Interarea light is pleased, and preserves youthful looks, and goes to deceive.The swelling of harnessing the river is full, tells vomiting, and cold type of pain in the abdomen is vomited and diarrhoea incessantly, and the insufficiency of stomach-QI cold-dysentery.

Radix Salviae Miltiorrhizae is bitter, is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for menoxenia, the amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia.Be used for the costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen caking, skin infection swells and ache, tumbling down is grieved, menoxenia, the amenorrhea dysmenorrhea, puerperal stasis of blood pain etc.Treatment costa sternales pain, lump in the abdomen caking, and menoxenia, amenorrhea dysmenorrhoea have good effect.The lid Radix Salviae Miltiorrhizae can break stagnated blood, mends fresh blood, peaceful tire, and the stillborn fetus that falls ends the metrorrhagia dysentery, the regulating menstruation arteries and veins.The application of Radix Salviae Miltiorrhizae in this compound recipe solved the syndrome of blood stasis of tumor patient pointedly; Radix Salviae Miltiorrhizae can microcirculation improvement, change hypercoagulability, promote blood circulation; Strengthen the groundwater increment of tumor tissues blood and the oxygen content of diseased region cancerous cell, reduce anoxic cell.

Sweet, the mildly bitter flavor of property Radix Ophiopogonis is slightly cold.GUIXIN, lung, stomach warp.Function with cure mainly YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Be used for dryness of the lung dry cough, the chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.Control dryness of the lung dry cough, spit blood, spitting of blood, consumptive lung disease, lung abscess, the asthenia dysphoria with smothery sensation is quenched one's thirst, and hinder in calentura Tianjin, dry mouth and throat, constipation.These article are sweet cold clear and rich, the heat of the kind lung that clears away heart-fire and yin nourishing relieving restlessness, and holding concurrently can clear and rich gastrointestinal and quench the thirst and moisturize.Effect with anti-experimental character arrhythmia, increase coronary flow.

Rhizoma Chuanxiong is gone into liver, spleen, three warmers three warps.Function cures mainly activating QI to alleviate the depression, and the method wind-dryness is wet, promoting blood circulation and stopping pain.Control air-cooled headache and revolve dizzyly, the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.Be used for menoxenia, amenorrhea dysmenorrhea, abdominal mass stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia." detailed outline " carries: " dampness, antidiarrheal dysentery, activating QI to alleviate the depression." ligustrazine is removed vascular smooth muscle (aortic article) spasm (epinephrine, potassium chloride cause).Can also expand coronary vasodilator, coronary blood flow increasing.The myocardial ischemia-anoxemia that the antagonism pituitrin causes.Alleviate the myocardial infarction lesion degree that the ligation arteria coronaria causes.

Semen Persicae is bitter, and is sweet, puts down the special medicine that closes for blood stasis blood.Bitter to let out stagnant blood, sweet with tissue regeneration promoting blood." medicineization justice ": Semen Persicae, bitter in the mouth can rush down heat in blood, and the body profit can be grown dryness of the intestine.If gross weight grinds many usefulness, walk Liver Channel, main broken blood-retention, water month by month; And pain all over, extremity wood numbness, left hemiplegia, left sufficient patient; Relax through the promoting the circulation of blood of invigorating blood circulation with it, the merit of eliminating blood stasis to promote regeneration of blood is arranged,, go into large intestine if few usefulness is mashed in peeling; Control blood depletion and just close, the dry dyschezia of blood with its make moist removing heat from blood and blood, has relieving accumulation of pathogens to lead to stagnant power.

Radix Angelicae Sinensis: its sweet in the mouth and weighing, so specially can enrich blood, its gas is light and hot, thus again can promoting the circulation of blood, invigorating middle warmer has, in the row benefit is arranged, the gas medicine in the sincere blood, the also panacea in the blood.About mending of assistant to mend then, thus can support nutrition blood, the QI invigorating spermatogenesis, settling five organs, body by force, beneficial mind, all tangible deficient diseases, nothing is unsuitable.Assistant logical to attack then, so the relieving constipation bitterly of dispelling, relieving rigidity of muscles and joints is controlled contracture, paralysis, card such as dry, puckery.Nutrient QI being deficient and exterior syndrome being not relieved person, assistant is with agent such as bavin, Pueraria lobota, fiber crops, osmanthus, the Biao Weire that can loose greatly, and show not hold back the person, and help with Radix Et Rhizoma Rhei and so on, again can consolidating superficial resistance.Precisely because gas Xin Erdong, so desire its quiet person when keeping away it, the sliding benefaction of property is defecated and is not consolidated the person when keeping away it.All cloudy moderate heat Sheng persons, the active blood of Radix Angelicae Sinensis, also non-institute is suitable, cloudy deficiency of YANG of middle-JIAO person, Radix Angelicae Sinensis can nourish blood, and is indispensable.

Rhizoma Et Radix Notopterygii property is hot, bitter in the mouth, temperature.Return bladder, kidney channel.Function cures mainly cold expelling, dispels the wind dehumidifying, pain relieving.Be used for the anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.Be used for anemofrigid cold, the headache body is painful.The hot temperature of these article, gas is male and loose, and the power of delivering is strong; The heresy of main loose Taiyang channel ailment said due to cold or exposure and cold-damp; Have that cold expelling dispels the wind, the merit of removing dampness to relieve pain, so kindly control wind-cold damp pathogen and attack table, fever with aversion to cold, the flesh table is lossless, headache stiffness of the nape, limb aching pain person; The same usefulness of medicine such as normal and Semen Persicae, Herba Asari, Rhizoma Atractylodis, Rhizoma Chuanxiong are like Notoptreygium Decoction of Nine Ingredients; If cold-damp lays particular stress on, headache heavy sensation of the body person, but medicines such as compatibility Radix Angelicae Pubescentis, manuscript, Rhizoma Chuanxiong are like Decoction of Notopterygium for Rheumatism.The Rhizoma Et Radix Notopterygii tanginess is to make the good volatile oil of drop pill.

The Radix Paeoniae Alba goes into liver, spleen channel, nourishing blood to suppress the hyperactive liver, and slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia, married woman's blood closes obstructed, and repercussive blood can lose pus, beneficial woman's blood." Japan hanako materia medica ": control wind, mend labor, all diseases of main woman, and all diseases in antenatal back, Tong Yueshui brings down a fever, relieving restlessness, QI invigorating, day hot disease of row, the pestilence miasma, mania and irritation, married woman's blood fortune, and hemorrhoidal hamorrhage are rushed down blood, hemorrhoid complicated by anal fistula.Carbuncle on the back, the skin ulcer scabies, headache makes eye bright, and conjunctival congestion is exerted meat.The many QI invigorating of redness of the skin or complexion person, white person controls blood.

The Myrrha blood blood stasis removing that looses, subduing swelling and relieving pain.Cure mainly traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.Bitter in the mouth, suffering, flat.Go into liver, spleen, the heart, kidney channel." Bencao Jingshu " carries it: " the ulna arthralgia is coerced costalgia with husband's breast abdomen, non-retention of blood stasis and because of using in blood deficiency person.Lochia goes many, and empty pain person should not use in the abdomen.Carbuncle has been burst and should not have been used.The non-heat in blood of conjunctival congestion skin nebula very person should not be used." join Olibanum, promoting blood circulation to remove blood stasis, circulation of qi promoting Shujin.

The Semen Cassiae hardship is sweet, is slightly cold, and is nontoxic." book on Chinese herbal medicine just " carried it: mildly bitter flavor is little sweet, and property is flat, little cold.Return liver, kidney, large intestine channel.Liver heat removing makes eye bright, relieving constipation.It is dizzy to be used to have a headache, and conjunctival congestion is dim-sighted, constipation.Control the wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, cirrhotic ascites, habitual constipation.Shennong's Herbal is classified Semen Cassiae as top grade, calls it, and " main optic atrohic blindness, order is excessive, skin is red, tunica albuginea, eye red logical, tear.The clothes benefit is with nothing left, makes light of one's life by commiting suicide "." Japan hanako materia medica " sayed it, and " help irritability, benefit is smart; Water is that the end is coated with, and the detumescence poison pastes temple and controls headache, pastes the brain heart again, ends serious epistaxis; Rest the head on, control wind syndrome of head, Semen Cassiae wins Semen sojae atricolor "." Chinese herbal medicine handbook commonly used is carried Semen Cassiae can " liver heat removing and eyesight improving, diuretic relieving constipation in Guangzhou army.Treating the liver inflammation, cirrhotic ascites, hypertension, infantile malnutrition, nyctalopia, wind heat ophthalmalgia, habitual constipation "." Hunan medicine will " is carried it and controls " giddy, beriberi, edema, pulmonary tuberculosis, the thoracic obstruction ".State Administration of Traditional Chinese Medicine organizes " the China's book on Chinese herbal medicine " write in recent years, and it is comparatively extensive to state its application, carries to say: " the liver heat removing kidney tonifying makes eye bright, the diuretic relieving constipation.Cure mainly conjunctival congestion and swelling pain, photophobia tear is many, optic atrohic blindness, nyctalopia, headache and dizzy, poor vision, cirrhotic ascites, dysuria, habitual constipation.External treatment toxic swelling, tinea disease ".Modern study shows that Semen Cassiae also contains steroidal compounds, chrysophanol, emodin etc. except that containing saccharide, protein, fat, in addition the trace elements iron of needed by human, zinc, manganese, copper, nickel, cobalt, molybdenum etc.Contained emodin, chrysophanic acid human body is had relieving asthma, function of gallbladder promoting, protect the liver, the blood pressure lowering effect, and necessarily antibiotic, antiinflammation are arranged.Wherein emodin monoglucoside, emodin anthrone, physcione have the serum cholesterol of reduction and cardiotonic.The Semen Cassiae element has the a-hydroxyl, can synthesize complex with the metal element, and metallic element is absorbed with very big influence.Modern clinical with the satisfaction of producing effects of Semen Cassiae treatment hyperlipemia, Semen Cassiae decocting or process tablets.For tea-drinking, there is the health care of prevention and treatment disease at Semen Cassiae parching to brown commonly used among the people end.

The little hardship of Spica Prunellae, liver heat removing, eliminating stagnation, diuresis; Control diseases such as pestilence, acute mastitis, ophthalmalgia, jaundice, gonorrhea, hypertension; Control that lymphoid tuberculosis, thyromegaly, scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia are shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.Spica Prunellae is the key medicine of clearing away liver-fire, Disperse hepatic depression, and what it cured mainly is the disease of Liver Channel mostly.These article are equipped with the Radix Angelicae Dahuricae, Semen Cassiae, but liver heat removing and eyesight improving control conjunctival congestion and swelling pain, be equipped with Concha Haliotidis, Ramulus Uncariae Cum Uncis, but the pancake liver-yang is controlled headache, dizziness; Be equipped with article such as Radix Scrophulariae, Bulbus Fritillariae Uninbracteatae, Concha Ostreae, but hard masses softening and resolving is controlled scrofula and is gone through tuberculosis." the southern regions of the Yunnan Province book on Chinese herbal medicine ": the liver-wind of dispelling, the network of passing through is controlled facial hemiparalysis.The row irritability is opened stagnation of liver-QI, ends bones and muscles pain, ophthal malgia, and the scrofula of loosing is stolen, whole body tuberculosis.

Radix Scutellariae has heat clearing and damp drying, and removing heat from blood is antiabortive, detoxicating functions.Cure mainly diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibiotic not worse than Rhizoma Coptidis, and does not develop immunity to drugs.We are by the strong characteristics of broad-spectrum antibacterial action, and it is special severe to be used in the fungal culture microbial contamination, fine with Radix Scutellariae extracting solution effect." Bencao Jingshu ": Radix Scutellariae, its property is respectful clearly, so remove evil: so bitter in the mouth dampness; So YIN-cold wins heat, so main all heat.All hot persons, pathogenic heat with all over heat also, jaundice, intestinal be out-of-the-way, let out dysentery, the disease of all damp and hot victory is also analysed it, and is then all sick from recover.Bitter cold can be removed damp and hot, thus small intestinal profit and water from pursuing, the source is clearly then flowed also clean.The blood person of closing, excess-heat is at blood system, instant heating human blood chamber, it is obstructed to make us amenorrhea, damp and hot separating, then Ying Qi is clearly and voluntarily also.Malignant boil cellulitis erosion person, heat in blood is then stayed knot, and is that carbuncle stain is mashed also: the acute scleritis person, the fire of moxibustion blood trouble also, the removing heat from blood heat extraction, then spontaneous recovery also.Radix Scutellariae has antiallergic action and antiinflammatory action: contained baicalin of Radix Scutellariae and baicalin can obviously suppress sensitized guinea pig rat small intestine in vitro and isolated tracheal to anaphylaxis contractile response that antigen produced; To passive general allergy and the Cavia porcellus passivity skin allergic reaction of Cavia porcellus and mice, baicalin and baicalin also have inhibitory action.Radix Scutellariae has refrigeration function, most evidences, and the active ingredient baicaligenin of Radix Scutellariae has refrigeration function.Radix Scutellariae has Detoxication, and baicalin has tangible Detoxication, and this possibly be because under the effect of glucuronidase, and baicalin decomposites glucuronic acid, and with due to multiple poisonous substance combines.10 milligrams of LD 50 that can improve strychnine of baicalin reach 2.5 times, and the hepatic glycogen content of carbon tetrachloride poisoning mice is increased.

Caulis Polygoni Multiflori is dicotyledon medicine polygonum multiflorum thunb ratan or leaf bine stem.Nourish heart, calm the nerves, collateral dredging dispels the wind, and controls the insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.Sweet little hardship, flat." book on Chinese herbal medicine is new again ": " bitter in the mouth, warm in nature, nontoxic." " decoction pieces is newly joined ": " pained little sweet." " Shaanxi Chinese herbal medicine ": " property is flat, sweet in the mouth." go into the heart, spleen, kidney, Liver Channel complex acid Semen Ziziphi Spinosae, grow the heart-yin, mind calming is refreshing; Join the Radix Rehmanniae, the nourishing YIN of nourishing blood; Join Radix Asparagi, Radix Ophiopogonis, clear asthenic fire, the moon nourishes heart; Join Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, expelling wind and dampness, Shu Li joint.

Fructus Forsythiae is bitter, is slightly cold.Return lung, the heart, small intestine meridian.Function is a heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Be used for carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm joining the army, the hyperpyrexia excessive thirst, coma is sent out speckle, the pyretic stranguria urine retention.The medicinal part of Fructus Forsythiae mainly is a fruit.Its shell, i.e. " sticking up " in " a kind of reed mentioned in ancient books sticks up detoxifying pills ".Contain forsythol, coumarin, oleanolic acid, Saponin, Citrin etc.Have effects such as heat clearing away, detoxifcation, eliminating stagnation evacuation of pus.Cure mainly warm, skin infection, scrofula, erysipelas, class's rash, influenza, be decocted in water for oral dose with fruit, or add in the prescription.Be usually used in anemopyretic cold.Nature,taste and action: Chinese medicine bitter in the mouth, cold nature.Heat-clearing and toxic substances removing, mass dissipating and swelling eliminating.The mongolian medicine bitter in the mouth, cool in nature." association's day " clearly, antidiarrheal.Cure mainly: Chinese medicine is controlled calentura from the beginning of, anemopyretic cold, and heating is vexed, laryngopharynx swelling and pain, macule, erysipelas, scrofula, carbuncle pyogenic infections from tumour or sore, acute nephritis, pyretic stranguria.The mongolian medicine subcutaneous ulcer of harnessing the Yellow River, intestinal twinge, " association day " disease, intestinal heat.The Sheng Nong's herbal classic ": main cold and heat, Mus flaccidity, scrofula, carbuncle, malignant boil, goiter, stagnation of pathogenic heat, diseases due to noxious agents produced by various parasites.

The Herba Asari acrid in the mouth, temperature is dispeled the wind, cold expelling, row water is had one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia." property of medicine opinion " carries: control cough with dyspnea, and aversion to wind, public attention, spasm of the extremities, the settling five organs six internal organs add courage, and peeling rheumatism ancient term for country school can end under the eye lacrimation induced by wind pathogen, makes eye bright, and opens in the heart to stagnate, and removes toothache, and main blood closes, and married woman's blood drop lumbago is the most effective in cure to headache due to pathogenic wind-heat.

The Chinese medicine Radix Polygoni Multiflori has the branch of Radix Polygoni Multiflori and Radix Polygoni Multiflori Preparata, and direct slicing is used as medicine and is Radix Polygoni Multiflori, uses the Semen sojae atricolor liquor to mix and dry to be used as medicine after the steaming to be Radix Polygoni Multiflori Preparata.The function of the two is different: the detoxifcation of Radix Polygoni Multiflori function, eliminating carbuncle, loosening bowel to relieve constipation are usually used in treating scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; The invigorating the liver and kidney of Radix Polygoni Multiflori Preparata function, benefiting essence-blood, black beard and hair, bone and muscle strengthening are used for blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body void etc.The Radix Polygoni Multiflori Preparata that the present invention adopted is the good merchantable brand of invigrating kidney.

Radix Angelicae Dahuricae acrid in the mouth warm in nature attaches to the lung and stomach meridians.Effect: expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping.Function cures mainly wind-damp dispelling, the evacuation of pus of invigorating blood circulation, granulation promoting pain relieving.Be used for headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus.Dispel the wind dampness, detumescence, pain relieving.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies." herbal classic " carried it: main woman's whitish metrorrhagia, and blood closes swelling of the vulva, cold and heat, public attention (wind syndrome of head) is invaded the order lacrimation, and the longue skin is moist." not Lu ": treat ailment said due to cold or exposure thirsty for a long time (thirsty for a long time or doubt works ' chronic diarrhea '), vomiting, fullness sensation in bilateral hypochondrium, wind is dizziness bitterly, eye itching." property of medicine opinion ": control the twinge of trusted subordinate's blood, exorcising, main woman's metrorrhagia and vomiting make eye bright, arresting lacrimation goes out, and treats married woman's drop blood, waist stomachache; Can lose pus.Be the good medicine of blood stasis dispelling of unstinging.

Radix Angelicae Sinensis: its sweet in the mouth and weighing, so specially can enrich blood, its gas is light and hot, thus again can promoting the circulation of blood, invigorating middle warmer has, in the row benefit is arranged, the gas medicine in the sincere blood, the also panacea in the blood.About mending of assistant to mend then, thus can support nutrition blood, the QI invigorating spermatogenesis, settling five organs, body by force, beneficial mind, all tangible deficient diseases, nothing is unsuitable.Assistant logical to attack then, so the relieving constipation bitterly of dispelling, relieving rigidity of muscles and joints is controlled contracture, paralysis, card such as dry, puckery.Nutrient QI being deficient and exterior syndrome being not relieved person, assistant is with agent such as bavin, Pueraria lobota, fiber crops, osmanthus, the Biao Weire that can loose greatly, and show not hold back the person, and help with Radix Et Rhizoma Rhei and so on, again can consolidating superficial resistance.Precisely because gas Xin Erdong, so desire its quiet person when keeping away it, the sliding benefaction of property is defecated and is not consolidated the person when keeping away it.All cloudy moderate heat Sheng persons, the active blood of Radix Angelicae Sinensis, also non-institute is suitable, cloudy deficiency of YANG of middle-JIAO person, Radix Angelicae Sinensis can nourish blood, and is indispensable.

The Radix Astragali is main with tonify deficiency, ability invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Be used for that insufficiency of vital energy and blood, skin infection cave in, difficulty in discharging of pus or burst for a long time and do not hold back the person.The Radix Astragali has the function of good promoting pus discharge and tissue regeneration strengthening, i.e. the abscess suppuration granulation promoting of disunion for a long time.Modern medicine study shows that the Radix Astragali includes and multiple antibiotic effective ingredient, and the ability enhancing body's immunological function, therefore can also be used to prevent the generation of some infectious disease." book on Chinese herbal medicine meets former " carries: " Radix Astragali is can tonifying five ZANG-organs all empty, controls the stringy pulse spontaneous perspiration, rushes down YIN-fire, removes lung-heat, losslessly then sends out, and has antiperspirant then to end." be the good medicine of promoting resistance and defence disease.

Rhizoma Gastrodiae is commonly used simply and famousr and precious Chinese medicine, diseases such as clinical dizzy, the numb limbs and tense tendons of being used to have a headache, infantile convulsion, epilepsy, tic, tetanus more.Rhizoma Gastrodiae embellishes but not dry, and the master goes into Liver Channel, is longer than suppressing the hyperactive liver to relieve the wind syndrome, and the disease of all liver-wind stirring up internallys, the vertigo is no matter deficiency and excess is key medicine.1, suppressing the hyperactive liver to relieve the wind syndrome.Rhizoma Gastrodiae matter is moistened many liquid, can nourishing blood for calming endogenous wind, can treat the headache, dizzy of blood deficiency liver-wind stirring up internally, and also can be used for infantile convulsion, epilepsy, tetanus.2, wind-expelling pain-stopping.Dizzy, the migraine and general headache that is used for that wind-phlegm causes, numb limbs and tense tendons, hemiplegia.Rhizoma Gastrodiae is suitable for the dizziness due to the endogenous wind.Endogenous wind causes three types of headache: one, liver-Yang sthenia type, and reveal any symptoms: headache and dizzy occurs simultaneously; Two, stagnation of turbid phlegm in middle-JIAO, reveal any symptoms: often the sensation head is heavy partially; Three, the patient that suffers from a deficiency of the kidney, reveal any symptoms: headache and dizzy is simultaneously with the symptom of hypomnesis.Rhizoma Gastrodiae is improper to the headache and dizzy that flu causes.Rhizoma Gastrodiae has calmness, analgesia, anticonvulsant action; Ability cerebral blood flow increasing amount reduces cerebral vascular resistance, slightly shrinks cerebrovascular, increases the coronary vasodilator flow; Can bring high blood pressure down, decreased heart rate has protective effect to myocardial ischemia; Gastrodia elata polysaccharide has immunocompetence.

The Cortex Eucommiae is the dry bark of the Eucommiaceae plant Cortex Eucommiae, is Chinese famous and precious tonic herb.Tool invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, many effects such as antiabortive.Shennong's Herbal is classified as top grade.Call its " cure mainly waist and knee, invigorating middle warmer, beneficial vital essence, hard muscles and bones, remove itch under cloudy wet, dribbling urination.Obey for a long time, it is anti-old to make light of one's life by commiting suicide." Cortex Eucommiae is Chinese peculiar medical material, its medicinal history is long, has a wide range of applications clinical.It has very high economic worth.In recent years, the expert has carried out careful repeatedly research to Cortex Eucommiae composition both at home and abroad, finds to contain necessary for human body threonine, methionine, isoleucine in the Cortex Eucommiae; 17 kinds of free amino acids such as lysine, and zinc, copper, magnesium; Ferrum, calcium, phosphorus, 15 kinds of trace element such as potassium.The Cortex Eucommiae has invigorating the liver and kidney, and rubbish in the body is removed in bone and muscle strengthening, strengthens the human body cell substance metabolism; Prevent that muscle skeleton is aging, the balance human blood-pressure, the decomposer inner cholesterol reduces body fat; Recover blood vessel elasticity, diuresis heat clearing away, broad-spectrum antiseptic; Stimulating central nervous system improves white blood cell count, remarkable efficacy such as enhancing human immune.

The Cortex Albiziae nature and flavor are sweet, flat.The merit that resolving depression and blood, mind calming, subduing inflammation are arranged.The effect that the irritability of controlling, melancholy, insomnia, lung abscess, carbuncle, scrofula, muscles and bones folding wound are arranged.Folks of china is cured the disease of long standing and well established with Cortex Albiziae, be written into the medical science history for a long time, puts down in writing like " herbal classic ": " main settling five organs and five will are made us joy and are forgotten melancholy." " detailed outline " record: " and blood, detumescence, pain relieving.”

The Radix Rehmanniae clearing away heat and promoting production of body fluid, after the cold, hemostasis; Be used for hot blast impairment of YIN, crimson tongue excessive thirst, send out speckle dermexanthesis, haematemesis, epistaxis, laryngopharynx swelling and pain.The Radix Rehmanniae clearing away heat and cooling blood, yin nourishing is promoted the production of body fluid; Be used for the calentura excessive thirst, send out speckle dermexanthesis, interior-heat caused by deficiency of YIN, haematemesis, epistaxis, diabetes, infectious hepatitis.Can promote blood coagulation, rising peripheral leukocytes; Ability heart tonifying, diuresis, rising blood pressure; The ability the liver protecting, blood sugar lowering; Raise immunity, Antiradiation injury and the effect of adrenocortical hormone appearance are arranged.

The Radix Curcumae promoting QI circulation for relieving depression, the removing heat from blood removing blood stasis with potent drugs.Control all pains of breast abdomen side of body rib, it is demented to lose the heart, and the calentura coma is spitted blood epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.1. " property of medicine opinion ": control woman's stagnated blood epigastric pain caused by emotional factors, cold air knot gathers, the warm vinegar clothes that rub.2. Tang Materia Medica: main accumulation of blood, the therapeutic method to keep the adverse QI flowing downwards, granulation promoting, hemostasis, broken stagnant blood, stranguria with blood, hematuria, incised wound.Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.Be used for the amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, the calentura coma, epilepsy is gone mad, the jaundice dark coloured urine

The present invention prepares process:

The manufacturing process of tablet of the present invention is: Radix Angelicae Sinensis 1000g, Radix Bupleuri 1000g, Radix Salviae Miltiorrhizae 1000g, Semen Persicae 1000g; Herba Asari 1000g, Radix Paeoniae Alba 1000g, Rhizoma Atractylodis Macrocephalae 1000g, Rhizoma Et Radix Notopterygii 1000g; Rhizoma Chuanxiong 1000g, Myrrha 1000g, Radix Polygalae 1000g, Semen Platycladi 1000g; Cortex Albiziae 1000g, Rhizoma Gastrodiae 1000g, Ramulus Uncariae Cum Uncis 1000g, Cortex Eucommiae 1000g.

Soak medical material 30 minutes to 1 hour, heated and boiled 30 minutes is filtered filtrate for later use; Filtering residue adds water, and heating was boiled 30 minutes for the second time, refiltered filtrate for later use; Filtering residue adds water again, and heated and boiled is 30 minutes for the third time, filters; Three filtratings are lumped together, and heating is concentrated into pasty state, obtains the raw material medicinal liquid; Add starch and be pressed into tablet.

Disease of the present invention is seen hyperactivity of YANG due to deficiency of YIN, and the manufacturing process of ailment said due to cold or exposure when invasion capsule is: get Fructus Forsythiae 1000g, Semen Cassiae 1000g, Radix Scutellariae 1000g, Radix Ophiopogonis 1000g, Radix Angelicae Sinensis 1000g; Radix Bupleuri 1000g, Radix Salviae Miltiorrhizae 1000g, Semen Persicae 1000g, Herba Asari 1000g, Radix Paeoniae Alba 1000g; Rhizoma Atractylodis Macrocephalae 1000g, Rhizoma Et Radix Notopterygii 1000g, Rhizoma Chuanxiong 1000g, Myrrha 1000g, Radix Polygalae 1000g; Semen Platycladi 1000g, Cortex Albiziae 1000g, Rhizoma Gastrodiae 1000g, Ramulus Uncariae Cum Uncis 1000g, Cortex Eucommiae 1000g.The water logging bubble that adding 5-10 doubly measures 1 hour extracts 2 times; Heating extraction 1 hour is concentrated into the extractum shape, becomes component 1; The residue medicinal residues added the 60-90% soak with ethanol 1 hour, extracted twice, each 1 hour; Merge extractive liquid, filters, and concentrates; The 80-160 order filters, and the 6000-10000 rev/min of supernatant after centrifugal is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams; Ultrafiltrate concentrating under reduced pressure relative density is the extractum of 1.38 (80 ℃), as component 2.Above-mentioned two kinds of extractum are mixed, and concentrate drying becomes dried cream, pulverizes, and adds dextrin, drying, and hot stream temperature is 80 ℃-100 ℃, gets raw material medicated powder, incapsulates patent medicine.

The present invention accompanies dizziness, vexed, dry mouth with bitter taste, powder method for preparing during liver-fire superinverse person: get Radix Angelicae Dahuricae 1000g, Spica Prunellae 1000g, Radix Polygoni Multiflori Preparata 1000g, Fructus Gardeniae 1000g, Radix Angelicae Sinensis 1000g; Radix Bupleuri 1000g, Radix Salviae Miltiorrhizae 1000g, Semen Persicae 1000g, Herba Asari 1000g, Radix Paeoniae Alba 1000g; Rhizoma Atractylodis Macrocephalae 1000g, Rhizoma Et Radix Notopterygii 1000g, Rhizoma Chuanxiong 1000g, Myrrha 1000g, Radix Polygalae 1000g; Semen Platycladi 1000g, Cortex Albiziae 1000g, Rhizoma Gastrodiae 1000g, Ramulus Uncariae Cum Uncis 1000g, Cortex Eucommiae 1000g; Earlier medical material is put into 10 times of amount ethanol, heating and refluxing extraction 2 times, each 45 minutes, extract active ingredient, 2 extracting solution are merged leave standstill.Again medicinal residues are added 10 times of water gagings, heating and refluxing extraction 3 times each 1 hour, merges 3 extracting solution; Merge above-mentioned two kinds of extracting solution, decompression recycling ethanol and to be concentrated into liquor strength be 0.5g crude drug/mL, behind the sucking filtration, the relative density of filtrating is about 1.06 (20 ℃); Above-mentioned filtrating is the macroporous adsorptive resins of 10L through volume, and with the deionized water or the distilled water eluting of 10 times of resin column volumes, 95% ethanol elution of 5 times of resin column volumes of reuse is collected ethanol elution, removes solvent, obtains the raw material medicinal liquid earlier; Get powder after the drying.Can directly convert mixing in water for oral taking.

Disease companion insomnia and dreamful sleep of the present invention, the method for preparing of honey refining pill was when gas lost blood stasis person: get Radix Rehmanniae 1500g, Radix Astragali 1500g, Semen Ziziphi Spinosae 1500g, Radix Curcumae 1500g, Caulis Polygoni Multiflori 1500g; Radix Angelicae Sinensis 1500g, Radix Bupleuri 1500g, Radix Salviae Miltiorrhizae 1500g, Semen Persicae 1500g, Herba Asari 1500g, Radix Paeoniae Alba 1500g; Rhizoma Atractylodis Macrocephalae 1500g, Rhizoma Et Radix Notopterygii 1500g, Rhizoma Chuanxiong 1500g, Myrrha 1500g, Radix Polygalae 1500g; Semen Platycladi 1500g, Cortex Albiziae 1500g, Rhizoma Gastrodiae 1500g, Ramulus Uncariae Cum Uncis 1500g, Cortex Eucommiae 1500g; Earlier said crude drug is ground into coarse powder, further pulverizes, cross 120 mesh sieves, the fine powder amount that enable pass is crossed 120 mesh sieves reaches 30%, and the fine powder of collecting through 120 mesh sieves gets fine powder a; Can not drop into multi-function extractor through the coarse powder of 120 mesh sieves again and extract twice, and add 8-10 times of water gaging for the first time and decocted 1 hour, and add 4-8 times of water gaging for the second time and decocted 1 hour, merge decocting liquid twice, and cross and filter filtrating; Heating is concentrated into pasty state, puts into 80 ℃ in baking oven oven dry postcooling, grinds to form fine powder b, with a with call in Mel after b mixes and process the sweet pill that refines.

Toxicological experiment:

1, acute toxicity test

The application mice carries out acute toxicity testing and shows: mouse stomach Chinese medicinal capsule agent of the present invention; Under 488.8g crude drug/kg dosage, the light activity minimizing appears in mice after the administration, recovers normal about 1 hour; Observed 7 days continuously after the administration; None animal dead, its overall health of patients, diet, to take the photograph water, urine and body weight gain all normal, and experimental result shows: the maximum dosage-feeding of mouse stomach Chinese medicinal capsule agent of the present invention is 488.8g crude drug/kg/d (LD 50＞488.8g crude drug/kg).Chinese medicine preparation clinical application every day total amount of the present invention is 0.1g crude drug/kg/d; Press weighing machine, the dosis tolerata of mouse stomach Chinese medicine preparation of the present invention is 4888 times of clinical patient.Point out this medicine acute toxicity low, clinical drug safety.

2, long term toxicity test

Select the SD rat for use; Give variable concentrations (18.0,6.0, the medicine pill of the present invention of 2.0g crude drug/kg), irritate stomach every day once, continuous 90 days; Respectively organized 1/2 animal (male and female half and half) extremely that lives in 24 hours after the last administration, all the other 1/2 animals continuation observation, 2 all backs are extremely alive.Duration of test is observed outward appearance, general behavior, food ration, the body weight change of animal, after the administration 90 days with carry out hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) in 2 weeks of drug withdrawal and check with indexs such as blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology.Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dose groups animal general state, all no abnormal variation of outward appearance sign, behavioral activity, food-intake and body weight gain; Three dose groups and matched group hematological examination, blood biochemical are learned, the urine biochemical analysis is all in normal range, do not have significant difference between group; Each is organized the main organs histopathological examination and is not seen obviously unusual.The These parameters drug withdrawal is not seen change after 2 weeks yet.This test dosage is respectively 180,60,20 times of clinical medicine dose; According to result of the test Chinese medicine composition of the present invention high, medium and low three dosage (18.0,6.0, the 2.0g crude drug/kg) administration in continuous 90 days does not have obvious influence to rat; No clear and definite toxicity target organ and sensitive indicator; The retardance toxic reaction is not seen in the convalescent period observation yet, points out the dosage safety property of Chinese medicine preparation clinical practice of the present invention higher.

3, animal local excitation test:

The guinea pig skin hypersensitive test of tablet of the present invention and tablet are to rat rectal application irritation test.

The result shows: skin anaphylactic test, and high dose group 0.8g (medicated powder)/kg, low dose group 0.1g (medicated powder)/kg are equivalent to intend 20 times, 2.5 times of clinical people's consumption [0.04g (medicated powder)/kg] respectively, through the skin administration, do not see that all animal produces allergy; Rectal application irritation test high dose group 5.0g (medicated powder)/kg, low dose group 3.2g (medicated powder)/kg is equivalent to intend 125,80 times of clinical people's consumption respectively; In official hour, observe mucous membrane of rectum and all do not have phenomenons such as hyperemia, edema; Histopathologic examination and blank group be no significant difference relatively, does not see tangible irritative response to occur every group of its overall health of patients of part animal of retaining; Body weight, breathing, circulation, central nervous system and extremity activity etc., all Non Apparent Abnormality reactions.

Pharmacodynamic experiment:

1 material: capsule of the present invention, Kunming kind white mice, biology department of Shandong University provides.

2 analgesic test method and results

2.1 the mice hot plate is caused the influence (experiment 1) of pain

2.1.1 material: female white mice, body constitution amount 16～20g.Equipment: constant water bath box, stopwatch, thermometer, graduated cylinder, beaker.Medicine: the suspension that capsule of the present invention is made into (high concentration 2.7g/ml, middle concentration 1.35g/ml, low concentration 0.675g/ml), ibuprofen (0.007g/ml), normal saline.

2.1.2 experimental technique

With the water bath topped up with water of constant water bath box, heating is regulated water temperature and is (60 ± 0.5) ℃; And preheating 10min, put 1 mice to hot plate at every turn, pick up counting simultaneously; Metapedes required time (s) appears licking in record, selects 30s to do the back experiment with the interior mice that licks metapedes.Qualified mice is divided into 5 groups each 10 at random, measures the basic threshold of pain (s) and the record of each group.Administration 3d, blank control group is irritated normal saline 15ml/kg, and positive controls is irritated ibuprofen 0.0105g/kg, and the high, medium and low dose groups of these article is irritated these article 40.50g/kg, 20.25g/kg, 10.12g/kg respectively.After the administration in the 5th day, the pain threshold behind measurement 15min and the 30min.Surpass the note 60s that 60s does not still lick metapedes.

2.1.3 result of the test

Table 1 capsule of the present invention causes the influence (X ± s) of pain to the mice hot plate method

Annotate: compare * P＜0.05, * * P＜0.01 with the blank group.

2.2 mouse writhing method (experiment 2)

Choose body weight 20 ± 2g, the basic threshold of pain is 30 of 5～15 seconds white mice, and male and female half and half are divided into three groups at random, and first group of normal saline irritated stomach; Second group of 0.25% ibuprofen irritated stomach, the 3rd group of these article suspension oral gavage, every day three times, continuous three days; Last administration 30min, lumbar injection 0.6% acetic acid 0.1/10g begins behind the 15min to observe and turns round the body number of times, stretches with hind leg; Abdominal part is close at the bottom of the cage, and abdominal muscle intermittently shrinks, and body reverses and is index, turns round the body number of times in the statistics 10min.The result sees table 2.

Table 2 is turned round body experimental result (X ± s)

Group	Dosage (g/kg)	Administration 10min turns round the body number of times
			1	0.6	48.21±3.56
2	0.3	38.32±4.16*
			3	0.16	23.51±5.38**

Annotate: with the normal saline group than * P＜0.05, * * P＜0.01

3. to rat trigeminal effect bitterly

3.1 laboratory animal: Wistar rat, body weight 200-220g.Biology department of Shandong University provides.Experiment medicine: ibuprofen; Preparation capsule of the present invention.

Experimental technique: get rat, male and female all can, random packet, 10 every group; Give rat oral gavage administration, dosage 10mg/kg, 60min after the administration, etherization by each group dosage; The abdomen position is fixed, and the incidence cropping is cut skin, separating muscle; Expose the cerebral dura mater between occipital bone and atlas, get the scotcil 3ul of new preparation, 1-2mm under the brain door bolt left side of rat, the about 1mm in atlas spinous process upper left side place with microsyringe; Be equivalent to spinal nucleus of trigeminal nerve tail sidepiece and slowly inject, sew up the incision, put in the cage and observe.Screaming, get rid of head and left hind with rat, to grab the facial number of times sum of homonymy fast be total attack times.With injection finish to the time that first set reaction occurs be incubation period, continue experiment in three minutes and stop; It is negative for spontaneous reaction not have this reaction in three minutes, has this reaction positive for spontaneous reaction.Experimental result, see table 3:

The different preparations of table 3 are to the effect of rat trigeminal pain

More than experiment shows that these article have the effect of significant analgesia, blood circulation promoting and blood stasis dispelling, applicable to symptoms such as headaches, for its clinical practice provides support.

Clinical data

1 data and method

1.1 diagnosis basis

" traditional Chinese medical science disease diagnosis criterion of therapeutical effect " (wind syndrome of head) diagnostic criteria with reference to State Administration of Traditional Chinese Medicine in 1994 promulgation: the position of 1. having a headache is many on head one side volume temporo, forehead, the crown, or a left side or the right side toss about in bed outbreak, or is full headache.Mostly the character of headache is jumping pain, twinge, distending pain, dusk pain, dull pain, or headache as split etc.The each outbreak of headache sustainable several minutes, several hours, a couple of days, lasting several weeks of person is arranged also.2. conceal and attack onset, increase the weight of gradually or outbreak repeatedly.And all point out through neck cranium doppler ultrasound (TCD) inspection: " cerebral vasospasm " reaches " cerebral arterial insufficiency ".Western medicine diagnose is with reference to " Neurology Department emergency case " diagnostic criteria of the qin chief editor of Sony-Ericson in 1996.

1.2 physical data

120 examples are the out-patient, are divided into treatment group and matched group at random.Treatment is organized in 60 examples, male 38 examples, women 22 examples; 16～58 years old age, average 37.5 years old; The course of disease 6.5 months～14 years, average 7 years.In matched group 60 examples, male 33 examples, women 27 examples; 15～59 years old age, average 38.4 years old; The course of disease 6 months～15 years, average 6.8 years.2 groups of physical data have comparability through statistical procedures there was no significant difference (P＞0.05).

The TCD that all goes before and after the case treatment checks.All get rid of because the headache due to the upper respiratory tract infection, sinusitis, intracranial infection, the cerebral tumor, epilepsy, cervical spondylosis.

1.3 Therapeutic Method

Matched group: use the treatment of Western medicine XIBILING JIAONANG merely.Obey 1 before the sleep every night.Treatment group: adopt treatment by Chinese herbs.Chinese medicine decoction of the present invention divides sooner or later to be decocted in water for oral dose for 2 times 1 dose of every day, and 2 groups is 1 course of treatment with 2 weeks all.After finish 1 course of treatment, observe the variation of headache and simultaneous phenomenon, and carry out relative analysis.2 groups of other drugs of during observing treatment, stopping using.

1.4 statistical method

Adopt chi-square criterion.

2 results

2.1 curative effect determinate standard

Cure: headache disappears, and the inspection of experiments chamber is normal, and it is normal that check rheoencephalogram and TCD recover, and follows up a case by regular visits to not recurrence more than half a year; Produce effects: headache and simultaneous phenomenon disappear, and the TCD inspection is normal, and following up a case by regular visits to has recurrence in half a year, but attack times and symptom alleviate than before; Effectively: headache alleviates, and attack times obviously reduces, and duration of seizure shortens or cycle stretch-out, and lab testing has improvement; Invalid: headache and simultaneous phenomenon do not have obviously and alleviate.

2.2 curative effect is (table 1) relatively

2 groups of curative effects of table 1 are (example) relatively

Group	n	Cure	Produce effects	Effectively	Invalid	Total effective rate (%)
							The treatment group	60	35	15	7	3	95
Matched group	60	21	11	5	12	61.7

Compare P＜0.01 with matched group

Visible by table 1, treatment group total effective rate is apparently higher than matched group, and 2 groups relatively, and significant differences (P＜0.01) is arranged.

2.3 untoward reaction

Untoward reaction does not all appear in 2 groups of cases.

Specific embodiment:

Embodiment 1: Chen, and the woman, 38 years old, in first visit in June, 2008.Readme migraine 10 years is surplus, outbreak repeatedly, the time heavy when light, about pain alternately,, be persistence and take out pain for very with the right side, meet and be the paroxysmal aggravation after tired or excited, MBV is few, clot, dysmenorrhea are arranged, and the companion feels sick, vomiting, dizziness, tinnitus.Nearly 1 week comes, and the headache outbreak is frequent, and inspection no abnormality seens such as brain electrical activity mapping, rheoencephalogram, head CT were once made in the aggravation of pain gesture.Western medicine diagnose is: angioneurotic headache.Not good through curative effect of medication such as clothes rotundine, ZHENNAONING, antipyrino-caffeinum citricum, flunarizines.Blood pressure 14.7/10kPa (110/75mmHg), light red tongue is dim, white and thin fur, stringy and rolling pulse.Card belongs to the exopathogen invasion and attack, qi depression to blood stasis, and venation is obstructed.Control suitable dispelling, collateral-activating, blood-activating analgetic.The side uses: Radix Angelicae Sinensis 10g, Radix Bupleuri 15g, Radix Salviae Miltiorrhizae 15g, Semen Persicae 15g, Herba Asari 10g, Radix Paeoniae Alba 10g, Rhizoma Atractylodis Macrocephalae 15g, Rhizoma Et Radix Notopterygii 15g, Rhizoma Chuanxiong 10g, Myrrha 10g, Radix Polygalae 10g, Semen Platycladi 15g, Cortex Albiziae 15g, Rhizoma Gastrodiae 10g, Ramulus Uncariae Cum Uncis 10g, Cortex Eucommiae 15g.Process pill, according to said method, adopt treatment by Chinese herbs after 10 days symptom obviously alleviate, the back symptom disappears basically after 30 days, for consolidating curative effect, adheres to the 60th day, all cards disappear.With examining not recurrence in 1 year.

Specific embodiment 2, model case: seal certain, woman, 34 years old, teacher.Left side migraine 1 year is surplus, pain during menstruation, and increase the weight of menstrual period.Grand mal was 1 time in 20 years old, continued about 5 days, and expression is painful, and according to the headache position, the companion feels sick, poor appetite, is waken up with a start by headache in often sleeping through hands commonly used, and each headache outbreak can not be adhered to work.Blood pressure 120/80mmHg, pulse condition is heavy thin, dark tongue quality, tongue fur is white, and examination of ocular fundus is normal.Examine and be the vascular nervous headache, side's usefulness: Radix Angelicae Dahuricae 10g, Spica Prunellae 10g, Radix Polygoni Multiflori Preparata 15g, Fructus Gardeniae 10g, Radix Angelicae Sinensis 15g; Radix Bupleuri 15g, Radix Salviae Miltiorrhizae 15g, Semen Persicae 15g, Herba Asari 10g, Radix Paeoniae Alba 15g; Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Et Radix Notopterygii 15g, Rhizoma Chuanxiong 10g, Myrrha 10g, Radix Polygalae 10g; Semen Platycladi 15g, Cortex Albiziae 10g, Rhizoma Gastrodiae 15g, Ramulus Uncariae Cum Uncis 10g, Cortex Eucommiae 15g.Headache is basic after obeying 7 doses disappears.The multiple work then taken 10 doses of recoveries from illness after 10 days, takes medicine 1 dose next day of again, serve on drug withdrawal in 1 month, follows up a case by regular visits to not outbreak in 1 year.

Specific embodiment 3: pay certain, man, 19 years old, student.Unknown cause headache over the past half year, double eyeball week, all dull pain of socket of the eye, causalgia.All no abnormal through the capable cranium CT of various big hospital, cervical vertebra X-ray film, examination of eyes, come the court's ophthalmology to go to a doctor.Except on the basis of paranasal sinus pathological changes, looking into supraorbital nerve incisura place has obvious tenderness, is diagnosed as supraorbital neuralgia.Taking prescription is: Radix Rehmanniae 10g, Radix Astragali 15g, Semen Ziziphi Spinosae 10g, Radix Curcumae 15g, Caulis Polygoni Multiflori 15g, Radix Angelicae Sinensis 15g; Radix Bupleuri 15g, Radix Salviae Miltiorrhizae 15g, Semen Persicae 10g, Herba Asari 10g, Radix Paeoniae Alba 15g; Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Et Radix Notopterygii 15g, Rhizoma Chuanxiong 15g, Myrrha 10g, Radix Polygalae 10g; Semen Platycladi 15g, Cortex Albiziae 10g, Rhizoma Gastrodiae 15g, Ramulus Uncariae Cum Uncis 10g, Cortex Eucommiae 10g.Take 10 doses, pain obviously alleviates, and continues to take symptom complete obiteration in 1 month, follows up a case by regular visits to and does not have recurrence in 1 year.

Specific embodiment 4: go into business certain, the man, 40 years old, during prescription on individual diagnosis readme suffer from headaches existing 5 years surplus, first side pain is very, and is left or right, is jumping pain, dragging pain, do not heal year in year out, every because of emitting wind to catch cold or emotion is not freely brought out.Inspection: it is conscious, and the optical fundus is normal, thin white fur of tongue, and stringy pulse or tight is diagnosed as ailment said due to cold or exposure and goes into brain type nervous headache.Adopt prescription of the present invention: Fructus Forsythiae 10g, Semen Cassiae 10g, Radix Scutellariae 15g, Radix Ophiopogonis 10g, Radix Angelicae Sinensis 15g, Radix Bupleuri 15g, Radix Salviae Miltiorrhizae 15g, Semen Persicae 15g; Herba Asari 10g, Radix Paeoniae Alba 10g, Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Et Radix Notopterygii 15g, Rhizoma Chuanxiong 15g, Myrrha 10g, Radix Polygalae 10g; Semen Platycladi 15g, Cortex Albiziae 15g, Rhizoma Gastrodiae 15g, Ramulus Uncariae Cum Uncis 10g, Cortex Eucommiae 10g, take 7 days after, the headache symptom make moderate progress; Then took 15 days, the headache symptom obviously alleviates, and the clothes that continue are to 45 days, headache completely without, recovery from illness is solid curative effect, reduces by half to take to 50 days to end.Visited 1 year, and do not see recurrence.

Claims (2)

1. a Chinese medicine preparation of treating nervous headache is characterized in that, the ratio of weight and number of various crude drug is: 10～20 parts of Radix Angelicae Sinensis, 10～20 parts of Radix Bupleuri, 10～20 parts of Radix Salviae Miltiorrhizaes; 10～20 parts in Semen Persicae, 10～20 parts of Herba Asaris, 10～20 parts of the Radix Paeoniae Albas, 10～20 parts of the Rhizoma Atractylodis Macrocephalaes, 10～20 parts of Rhizoma Et Radix Notopterygiis; 10～20 parts of Rhizoma Chuanxiongs, 10～20 parts of Myrrhas, 10～20 parts of Radix Polygalaes, 10～20 parts of Semen Platycladi; 10～20 parts of Cortex Albiziaes, 10～20 parts in Rhizoma Gastrodiae, 10～20 parts of Ramulus Uncariae Cum Uncis, 10～20 parts of the Cortexs Eucommiae.

2. method for preparing of treating the Chinese medicine preparation of nervous headache according to claim 1; It is characterized in that the dosage form of said preparation is a honey refining pill, its preparation method comprises: earlier said crude drug is ground into coarse powder; Further pulverize again; Cross 120 mesh sieves, the fine powder amount that enable pass is crossed 120 mesh sieves reaches 30%, and the fine powder of collecting through 120 mesh sieves gets fine powder a; Can not drop into multi-function extractor through the coarse powder of 120 mesh sieves again and extract twice, and add 8-10 times of water gaging for the first time and decocted 1-2 hour, and add 4-8 times of water gaging for the second time and decocted 1-2 hour, merge decocting liquid twice, and cross and filter filtrating; Heating concentrates said filtrating to pasty state, puts into 80 ℃ of oven dry of baking oven postcooling, grinds to form fine powder b, with a with call in Mel after b mixes and process the sweet pill that refines.