CN104474470B - The pharmaceutical composition of adverse reaction after a kind of medicine anesthesia - Google Patents

The pharmaceutical composition of adverse reaction after a kind of medicine anesthesia Download PDF

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Publication number
CN104474470B
CN104474470B CN201410712705.6A CN201410712705A CN104474470B CN 104474470 B CN104474470 B CN 104474470B CN 201410712705 A CN201410712705 A CN 201410712705A CN 104474470 B CN104474470 B CN 104474470B
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adverse reaction
medicine
pharmaceutical composition
seed
root
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Expired - Fee Related
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CN201410712705.6A
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CN104474470A (en
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吴玲
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The pharmaceutical composition of adverse reaction, is formed by following medicine preparation after being anaesthetized the invention provides a kind of medicine：Spina date seed 10g, seed of Oriental arborvitae 10g, cortex albiziae 10g, Polygonum multiflower knotweed 12g, peach kernel 8g, bark of eucommia 10g, root of Dahurain angelica 11g, radix bupleuri 12g, monkshood 8g, radix aconiti agrestis 10g, frankincense 10g, myrrh 10g, root tuber of aromatic turmeric 10g, asarum 8g.The present invention has the effect of notable to adverse reaction after medicine local anaesthesia.

Description

The pharmaceutical composition of adverse reaction after a kind of medicine anesthesia
Technical field
The medicine of adverse reaction, belongs to pharmaceutical technology field after being anaesthetized the present invention relates to a kind of medicine.
Background technology
Clinically many operations need to carry out local anaesthesia, but when being anaesthetized, effect is bad sometimes or operates The reasons such as difficulty are, it is necessary to increase the dosage of arcotic, so as to cause the adverse reaction of different degrees of anaesthetic, such as dizzy, Terrified uneasiness, say more, tremble, anxiety, or even mental derangement and clonic convulsion, respiration inhibition etc. occurs, clinical treatment is more Based on Western medicine, but it can usually aggravate when use western medicine or increase more adverse reactions.
The content of the invention
In order to solve the above-mentioned technical problem, the drug regimen of adverse reaction after being anaesthetized the invention provides a kind of medicine Thing.The present invention is pure Chinese medicinal preparation, will not aggravate or increase more adverse reactions.
Technical scheme is as follows：The pharmaceutical composition of adverse reaction after a kind of medicine anesthesia, by with prescribe medicine Thing is prepared：Spina date seed 10g, seed of Oriental arborvitae 10g, cortex albiziae 10g, Polygonum multiflower knotweed 12g, peach kernel 8g, bark of eucommia 10g, root of Dahurain angelica 11g, bavin Hu 12g, monkshood 8g, radix aconiti agrestis 10g, frankincense 10g, myrrh 10g, root tuber of aromatic turmeric 10g, asarum 8g.
The preparation method of the present invention is as follows：Take each taste of the above, 60% alcohol refluxs for adding 8 times, 6 times amounts extract 2 times, often Secondary 2 hours, ethanol is reclaimed, it is 1.10-1.15 to be concentrated to relative density.
The present invention can also on the basis of existing technology, prepare piece agent, capsule, pill, dispersible tablet, buccal tablet, Dripping pill etc..
The present invention is evident in efficacy, can effectively treat adverse reaction after arcotic.
Clinical data
There is the case 50 of adverse reaction in observation, is the patient of adverse reaction occur after operation local anaesthesia, wherein 20 There is cacesthesia, dysphoria, muscular tremor；30 there is cacesthesia, convulsions, respiration inhibition.Patient occurs bad anti- At once start medication.Medication is oral medicine of the present invention, and after treating 5 minutes, the adverse reaction symptom for having 28 patients disappears completely Lose, routine inspection blood pressure, pulse are normal, and after 10 minutes, the adverse reaction for there are 19 patients again is wholly absent, and is felt Very good, routine inspection blood pressure, pulse are normal；15 minutes are spent again, and the adverse reaction of remaining patient is wholly absent, self sense Feel good, routine inspection blood pressure, pulse are normal.
Embodiment
With reference to embodiment, the present invention is further illustrated.
Embodiment 1
Take spina date seed 10g, seed of Oriental arborvitae 10g, cortex albiziae 10g, Polygonum multiflower knotweed 12g, peach kernel 8g, bark of eucommia 10g, root of Dahurain angelica 11g, radix bupleuri 12g, monkshood 8g, radix aconiti agrestis 10g, frankincense 10g, myrrh 10g, root tuber of aromatic turmeric 10g, asarum 8g, add 60% alcohol reflux of 8 times, 6 times amounts Extraction 2 times, 2 hours every time, ethanol is reclaimed, it is 1.10-1.15 to be concentrated to relative density.

Claims (1)

1. the pharmaceutical composition of adverse reaction after a kind of medicine anesthesia, it is characterised in that formed by following medicine preparation： Spina date seed 10g, seed of Oriental arborvitae 10g, cortex albiziae 10g, Polygonum multiflower knotweed 12g, peach kernel 8g, bark of eucommia 10g, root of Dahurain angelica 11g, radix bupleuri 12g, monkshood 8g, radix aconiti agrestis 10g, frankincense 10g, myrrh 10g, root tuber of aromatic turmeric 10g, asarum 8g.
CN201410712705.6A 2014-12-02 2014-12-02 The pharmaceutical composition of adverse reaction after a kind of medicine anesthesia Expired - Fee Related CN104474470B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410712705.6A CN104474470B (en) 2014-12-02 2014-12-02 The pharmaceutical composition of adverse reaction after a kind of medicine anesthesia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410712705.6A CN104474470B (en) 2014-12-02 2014-12-02 The pharmaceutical composition of adverse reaction after a kind of medicine anesthesia

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CN104474470A CN104474470A (en) 2015-04-01
CN104474470B true CN104474470B (en) 2017-12-05

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102078520A (en) * 2011-01-10 2011-06-01 董春玲 Chinese medicinal preparation for treating nervous headache and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102078520A (en) * 2011-01-10 2011-06-01 董春玲 Chinese medicinal preparation for treating nervous headache and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
中西医结合治疗带状疱疹后遗神经痛37例;刘觉芳;《山西中医》;19990603;第15卷(第3期);第23页 *
化瘀定志汤治疗顽固性失眠86例临床观察;赵恒志;《河南中医》;20051210;第25卷(第12期);第44-45页 *

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