CN101966137A - Multi-efficacy skin-care preparation composition as well as preparation method and application thereof - Google Patents

Multi-efficacy skin-care preparation composition as well as preparation method and application thereof Download PDF

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CN101966137A
CN101966137A CN 201010297412 CN201010297412A CN101966137A CN 101966137 A CN101966137 A CN 101966137A CN 201010297412 CN201010297412 CN 201010297412 CN 201010297412 A CN201010297412 A CN 201010297412A CN 101966137 A CN101966137 A CN 101966137A
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agent
aloe
antibacterial
extract
skin
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CN101966137B (en
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韩海星
张巍
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Han Haixing
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Tianjin Sinosh New Material Technology Co Ltd
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Abstract

The invention relates to a multi-efficacy skin-care preparation composition as well as a preparation method and application thereof. The multi-efficacy skin-care preparation composition is prepared from the following materials by weight: 2 to 20% of superfatting agents, 5 to 10% of aloe juice with fresh nutritious ingredients, 0.3 to10% of antibacterial agents DP300, 5 to10% of cyclodextrin sorbents, 5 to 20% of closed alcohol refreshing agents and menthol lactate, 5 to 10% of solubilizers CO-40, propylene glycol and the like and 20 to 80.5% of solvent water. The preparation composition not only has a cooling effect, but also has the functions of effectively repairing damaged skin of women and relieving allergy because soft ingredients of natural aloe are added, and also lowers the probability on nerve paralysis because of using cooling products for a long time. The invention has the advantages of simple production process, low cost of materials, remarkable effect, strong applicability and remarkable economic benefit and social benefit.

Description

Multi-efficiency skin care formulation compositions and preparation method and application thereof
Technical field
The present invention relates to a kind of multi-efficiency skin care formulation compositions and preparation method and application thereof.
Background technology
" skin protection " become the thing that current society is the most popular, paid close attention to by people.The skin of human body can be divided into epidermis and corium haply; epidermis is exposed in the air; because it is aging with extraneous friction portion epidermis for a long time; form the harder horny layer of quality; it is the protective layer of human body, and women's privates skin horny layer is very thin, and some places almost do not have horny layer; so very tender and lovely being very easy to of skin is subjected to extraneous destruction, and corium is exposed in air.
The present sanitary towel that uses, it is soft that the sanitary pad seems, observing its skin-material earlier at microscope finds to have a lot of jagged fibers to exist, and hardness is very big, and this fibrid is very difficult perceived, if life-time service zigzag fiber can be constantly with horny layer, cells of superficial layer destroys, corium is exposed in the air, if avoid contacting the self-regeneration that this type of material damaged cell can be slowly this moment, but be can be not little at this moment by the epidermis area because of impaired of people's perception, can't detect by an unaided eye, can not produce sense of discomfort yet,, let alone to continue to destroy impaired skin so the women still adheres to using this series products.The bonding force of impaired epidermis peripheral cell extremely descends, there is friction can cause large stretch of desquamation slightly, sanitary towel, the sanitary pad can spray one deck lyophobic dust in order to pursue absorption rate on the material of top layer, this class material is just as one " time bomb "-it can not produce any bad effect to the skin of health, will cause allergy in case touch the corium part, show redness etc. clinically, various antibacterials in the while menses, pathogenic bacterium under the obstruct that does not have epidermis person of outstanding talent do not show mercy attached to hypodermal cell on breed, metabolism finally causes infecting!
Summary of the invention
The object of the invention is to provide a kind of have multi-efficiency skin care formulation compositions and preparation method and application thereof, can overcome the defective of prior art, can effectively improve the compliance on sanitary towel, protective pad top layer, reach the mechanical friction coefficient that reduces between fabric and the skin by the softening fabrics surface fiber, thereby effectively lower women or the tender and lovely skin of baby because of the impaired probability of mechanical friction; A large amount of Aloe polysaccharides and a spot of refrigerant composition are contained in the hygienic article top layer that is sprayed with the new healthy functions preparation of clean U.S. after testing, it not only can be alleviated effectively because of diminishing the allergy that skin produces, red and swollen problem, strengthen body sense permeability, also provide material base simultaneously for self repairing of cell.Processing technology of the present invention is simple, and cost of material is cheap, and effect is remarkable, and the suitability is strong, economic benefit and obvious social benefit.
A kind of quality with multi-efficiency skin care formulation composition material provided by the invention is formed:
Superfatting agent 2--20%
Antibacterial 0.3--10%
Natural plant extracts 5--10%
Adsorbent 1--10%
Salubrious agent 5--20%
Flavouring agent 0.1--10%
Antiseptic 0.1-0.3%
Solvent 20--80.5%
Wherein, superfatting agent: at least a in water solublity Fructus Canarii albi grease, cocoyl glyceride, PEG-75, the water solublity Semen Armeniacae Amarum grease;
Antibacterial: at least a in triclosan, chlorhexidine acetate, chlorhexidine gluconate, trichlorine kappa, benzalkonium chloride, benzalkonium bromide or the polyhexamethylene guanidine;
Natural plant extracts: the Aloe polysaccharide extracting solution (for example, 50% water extract), green tea powder (green tea is clayed into power), camomile extract aqueous solution liquid are (for example, 56%), willherb extract aqueous solution, shikonin extract are (for example, 1% water extract), the Radix Hamamelidis Mollis extracting solution (for example, 1% water extract), at least a in bamboo extracting solution (for example, 60% dry distillation liquid) or the cucumber extract (alcohol extraction 10: 1);
Adsorbent: at least a during cyclodextrin, food stage silicon dioxide, tea polyphenols or Oleum Ricini are misery;
Salubrious agent: at least a in Borneolum Syntheticum, Oleum menthae, Oleum menthae, Mentholum, menthyl lactate, menthyl acetate, Herba Menthae glycerol ketals or the Herba Menthae glycerol acetonide ether;
Solvent: at least a in propylene glycol, Macrogol 200, PEG400, Macrogol 600, castor oil hydrogenated or the water.
Described flavouring agent is essence or quintessence oil;
Described antiseptic is at least a in triclosan, Kazon, methyl hydroxybenzoate, propylparaben or the sodium benzoate.
The quality of the raw material of a kind of multi-efficiency skin care formulation compositions provided by the invention is formed:
Softener 2%-20%
Nourish composition 5%-10%
Antibacterial 0.3%-10%
Adsorbent 5%-10%
Salubrious agent 5%-20%
Solubilizing agent 5%-10%
Solvent 20%-80.5%
Softener uses superfatting agent commonly used in the personal care articles, at least a in water solublity Fructus Canarii albi grease, cocoyl glyceride, PEG-75, the water solublity Semen Armeniacae Amarum grease;
Nourish into component selections and use fresh Aloe juice in the natural plant extracts, i.e. Aloe polysaccharide extracting solution, it is rich in Aloe polysaccharide.
Antibacterial uses the DP300 of highly effective and safe.
Adsorbent has been selected the high-efficiency adsorbent of cyclodextrin series for use.
The menthyl lactate that comprises the pure and mild low irritant of highly purified closure in the salubrious agent.
Solubilizing agent comprises CO-40, propylene glycol etc.
Solvent has been selected high-purity deionized water for use.
Alternatively, a kind of have a multi-efficiency skin care formulation compositions, and its primary raw material is formed and the quality proportioning is:
Water solublity Fructus Canarii albi oils and fats 10%
Additive 1%
Propylene glycol 20%
Aloe polysaccharide extracting solution (50% aqueous extract) 5%
Water 64%
Additive is: at least a in Aloe essence, Aloe quintessence oil, triclosan, Kazon, methyl hydroxybenzoate, propylparaben or the sodium benzoate.
Alternatively, a kind of have a multi-efficiency skin care formulation compositions, and its primary raw material is formed and the quality proportioning is:
Semen Armeniacae Amarum oils and fats 10%
Camomile extract (56% water extract) 5%
Propylene glycol 20%
PEG400 10%
Triclosan 0.3%
Menthyl lactate 5%
Cyclodextrin 10%
Water 41.7%
Provided by the invention have a step that multi-efficiency skin care formulation preparation of compositions method comprises:
1) by measuring the solid material in the recipe ingredient, single grinding is respectively sieved, and it is stand-by to get 200-300 μ m;
2) fully mix with solvent and other auxiliary agents by superfatting agent, natural plant extracts, antibacterial, the additive of metering recipe ingredient;
3) two kinds of components of above-mentioned steps are mixed, stir to clarify the transparent product that is.
According to the multi-efficiency skin care formulation of the method preparation, can reach 2 years with upward stability with the multi-functional of sanitary towel, sanitary pad, wet tissue or the diaper of its preparation.
The application of described multi-efficiency preparation compositions is used to prepare sanitary towel, sanitary pad or diaper.
By adding natural plant extracts composition, softener, antibacterial, can make sanitary towel, sanitary pad or paper diaper surface layer reach nourishing, submissive, bacteriostatic effect
Added refrigerant composition, made sanitary towel, sanitary pad or paper diaper surface layer reach nourishing, submissive, antibacterial, refrigerant.
Add adsorbent, made sanitary towel, sanitary pad or paper diaper surface layer reach nourishing, submissive, antibacterial, refrigerant, absorption abnormal flavour, regulated pH value.
Multi-efficiency skin care formulation compositions provided by the invention and preparation method and application thereof can overcome the defective of prior art.Can effectively improve the compliance on sanitary towel, protective pad top layer: reach the mechanical friction coefficient that reduces between fabric and the skin by the softening fabrics surface fiber, thereby effectively alleviated the tender and lovely skin of women because of the impaired probability of mechanical friction; A large amount of Aloe polysaccharides and a spot of refrigerant composition are contained in the hygienic article top layer that is sprayed with healthy functions preparation of the present invention after testing, it not only can be alleviated effectively because of diminishing the allergy that skin produces, red and swollen problem, strengthen body sense permeability, also provide material base simultaneously for self repairing of cell.The present invention not only has the algefacient effect, has added the gentle composition that protects of aloe simultaneously, and it can the impaired skin of effective for repairing women, alleviate effect hypersensitive, has reduced the probability that uses refrigerant product to benumb nerve because of long-time.Processing technology of the present invention is simple, and cost of material is cheap, and effect is remarkable, and the suitability is strong, economic benefit and obvious social benefit.
Description of drawings
Fig. 1 is common sanitary towel and has sprayed the change curve of weak acid skin protectant sanitary towel top layer pH value in 2 hours.
Fig. 2 is common sanitary towel and has sprayed the refrigerant composition in the sanitary towel top layer residual change curve of refrigerant composition in 54 ℃ of 7 days processes that has refrigerant composition skin protectant.
Fig. 3 is the gas chromatogram of refrigerant composition menthol, peppermint ester.
The specific embodiment
Below by embodiment the present invention is specifically described; they only are used for the present invention is further detailed; can not be interpreted as limiting the scope of the invention; those skilled in the art makes some nonessential improvement and adjustment according to the content of the invention described above; all belong to protection domain of the present invention, the percentage concentration among the present invention is mass percentage concentration.Primary raw material is as follows:
1) Aloe polysaccharide extracting solution: Aloe polysaccharide is 50% aqueous solution (the huge group of ShenFang,SiChuan bio tech ltd).
2) OLIVEM 300, and Chinese is a water solublity Fructus Canarii albi oils and fats.
3) HE, Chinese are cocoyl glyceride.
4) HP-β-CD, HP-.
5) propylene glycol.
6) CO-40 menthol.
8) menthyl lactate.
9) DP300 molecular formula: Cl2H7Cl3O2.
10) DL, polyhexamethylene guanidine (PHMG).
11) water.
Example 1
The material name addition (quality, %)
Aloe polysaccharide 25
DL 5
PEG-400 1.5
OLIVEM?300 2
Water 66.5
This product can effectively improve the compliance on sanitary towel, protective pad top layer: reach the mechanical friction coefficient that reduces between fabric and the skin by the softening fabrics surface fiber, thereby effectively alleviated the tender and lovely skin of women because of the impaired probability of mechanical friction; Detect the hygienic article top layer that is sprayed with multi-efficiency healthy functions preparation of the present invention through ultraviolet spectra and contain a large amount of Aloe polysaccharides, it not only can be alleviated effectively because of diminishing the allergy that skin produces, red and swollen problem, also provides material base for self repairing of cell simultaneously.Contain high-efficiency antimicrobial components D P-300 in the formula for a product, guaranteed product microbiological indicator qualified in 2 years stability tests.
The effect checking
Get application example 1 and carry out following effect checking and index of correlation:
1) stability test:
Reference standard: target level of product quality, disinfection technology standard
Sample liquid: placed naturally 90 days at 37 ℃ of calorstats under the liquid seal state
Testing result sees Table 1
Table 1:
Print: spray the back to the stability of the hygienic article of non-woven fabrics, PE making hole film, three kinds of materials of pure cotton non-woven fabrics 90 days, testing result sees Table 2.
Table 2:
Figure BSA00000290421700052
Figure BSA00000290421700061
2) microbial contamination
Condition: placed 90 days 2 years stability tests with reference to (37 ℃) calorstat under " disinfection technology standard " sealing state
Sample: spray each 9 in back three kinds of samples, spray each 9 of back three kinds of sample plastic sealing packs.
Detect the disposable use hygienic article of foundation: GB15979-2002 sanitary standard, measurement result sees Table 3.
Table 3:
Figure BSA00000290421700062
Example 1 multi-efficiency healthy functions preparation is sprayed on the sanitary pad surface, is positioned over the mensuration of 37 ℃ 90 (2 years stability) day back bacterial detection, fungus colony sum, and testing result meets the disposable use hygienic article of GB15979-2002 sanitary standard.
3) Aloe polysaccharide content detection
Reference standard: QBT 2488-2006 used for cosmetic Aloe juice, powder sample treatment: choose 3 of blank sanitary towels, carry out every 0.1g at laboratory and precisely spray; 3 of control samples.
Test instrunment: Tianjin, island ultraviolet-uisible spectrophotometer, UV-1750.
Concrete operations: sanitary towel's top layer entire chapter torn get, with carrying out concentrating in right amount after-filtration behind the ethanol extraction, carry out spectral scan, measurement result sees Table 4.
Table 4:
Figure BSA00000290421700063
Prove the sanitary towel of spray application example 1, top layer Aloe polysaccharide content average 17.2mg after testing
Example 2
Material name addition %
Aloe polysaccharide extracting solution (50% aloe water extracting solution) 10
Shikonin extract (1% aqueous extract) 5
HE 20
Propylene glycol 20
DL 8
DP300 0.2
Water 36.8
This prescription compares with example 1, and it has extraordinary submissive effect, adds shikonin extract on the basis of original Aloe polysaccharide in addition, can effectively prevent skin allergy, further takees good care of skin.
Treating excess syndrome example 2 samples carry out following effect test.
1) stability test
Sample liquid: its liquid 37 ℃ of heat stability experiment, the following 37 ℃ of calorstats of sealing state are placed not stratified, invariant color in 90 days naturally.
Print: Aloe healthy functions preparation sprays color, the outward appearance equal no change of back to the hygienic article of non-woven fabrics, PE making hole film, three kinds of materials of pure cotton non-woven fabrics
2) microbial contamination
Reference standard: with reference to " disinfection technology standard "
Sample treatment: spray back three kinds of samples each 9, clip and effectively spray the position and detect
Detect the disposable use hygienic article of foundation: GB15979-2002 sanitary standard
Measurement result sees Table 5
Table 5:
3) after example 2 multi-efficiency healthy functions preparations are sprayed on the sanitary pad surface, the mensuration of compliance.
Reference standard: the slim bonded non-wovens test method of ZB W 04002-86 " 5.5.2 measures the hard and soft degree of fabric.
Sample treatment: spray each 9 in back three kinds of samples, spray each 9 of back three kinds of sample plastic sealing packs
Use instrument: LFY-208 swing type fabric sofetening degree analyzer
Measuring unit: Shandong Textile research institute
Operating procedure:
1. cut the sample of long 2.54cm, wide 5.08cm.Each 10 of vertical, horizontal.
2. adjust the instrument level, make pendulum pointed zero-bit, the house bobbin of sample clamp and pendulum upper end is at a distance of 1.27cm (concordant with sample bar high scale on the specimen holder).
3. the 0.64cm length with the sample upper end is sandwiched in the specimen holder, and the house sheet overlaid of the 0.64cm length of lower end and pendulum upper end is regulated the pointer load, counterweight is sandwiched in the 50cm or 100cm counterweight groove of pendulum pointer bottom.The selection of pendulum pointer load and counterweight groove makes the central authorities of the power infra dish at quarter of flexural rigidity as far as possible.
4. turn on the power switch, press start button, the sample bar begins to rotate with right-to-left from left to right.Read the dial reading Rg (being accurate to 0.1) of pendulum pointer indication when sample breaks away from the house sheet respectively.Press stop button.
5. record the reading of the arithmetical average of Rg with a sample left and right sides as this this test of piece sample.
6. make the Rg of all the other 9 samples by same steps as, calculate the arithmetical average (being accurate to 0.01) of 10 samples.
7. by formula calculate: S=Rg * (W * A) * 0.28 * 9.8 * 10-6
In the formula: S---hard and soft degree, (N);
Rg---the vertical or horizontal respectively arithmetical average of 10 readings;
The counterweight quality of W---each grade, g;
A---the counterweight groove of placing counterweight and length of support from, inch.
Test result sees the following form 6
Table 6:
Figure BSA00000290421700081
Prove that after tested example 2 multi-efficiency healthy functions preparations are sprayed on the sanitary pad surface, compliance has increased by 25% than blank sanitary towel protective pad, has reduced the loss ratio that brings women's skin because of mechanical friction.
Example 3
Material name addition %
Aloe polysaccharide (50%) 15
HE 20
Propylene glycol 30
DL 14
DP300 0.3
HP-β-CD 5.7
Water 15
This sample is submissive, and has stronger fungistatic effect, and absorption simultaneously has a synergism with antibacterial, reduces probability hypersensitive.Rich ester agent in the prescription can be played good submissive effect to the top layer non-woven fabrics, and forms one deck isolating membrane on its surface, has avoided the injured again probability of impaired skin;
Antibacterial-the DP300 of highly effective and safe can play the effect that suppresses its metabolism, breeding to harmful bacterium, the pathogenic bacterium in the menses, thereby controlling infected skin further worsens, and the metabolite of various microorganisms can be adsorbed by the cyclodextrin in the prescription, that is to say that the cyclodextrin distinctive molecular structure can adsorb the metabolite of antibacterial, pathogenic bacterium, and other amine gas, form one deck isolating membrane on its surface, make it and to contact with tender and lovely skin, thereby reduce skin probability hypersensitive;
Contained HP-β-CD in the prescription, the oligosaccharide compound of from pure natural plant, extracting, it is trapezoidal that working substance is hollow
Frustum cone structure, its intracavity shows electropositive, can the metabolite of antibacterial effectively be wrapped up, and the PH of women's private portion has certain regulating action.
Can eliminate clinical manifestation substantially by above-mentioned two processes, alleviate women's slight illness, for the women is recovered fully, Free from Sub-health, need repair impaired epidermis cell fully, and Aloe polysaccharide provides fissional raw material and catalyst with the rich ester agent that is absorbed by the body easily, accelerates fissional speed, gets well early.
The effect checking:
Stability, microbial contamination, Aloe polysaccharide content, compliance are tested with example 1.
1) bacteriostasis rate detects
Reference standard: with reference to " disinfection technology standard ".
Testing conditions: (37 ℃) calorstat is placed 90 days 2 years stability tests under the sealing state.
Sample treatment: spray each 9 in back three kinds of samples, spray each 9 of back three kinds of sample plastic sealing packs.
Detect the disposable use hygienic article of foundation: GB15979-2002 sanitary standard, test result sees Table 7.
Table 7:
Figure BSA00000290421700091
Test result proves, example 3 multi-efficiency healthy functions preparations are sprayed on the sanitary pad surface, the mensuration that is positioned over 37 ℃ 90 (2 years stability) day back bacteriostasis rate is all greater than 90%, testing result meets the disposable use hygienic article of GB15979-2002 sanitary standard, reaches stronger bacteriostasis.
2) adsorption effect
1. the scope of application
This standard code triethylamine detect the detection method and the standards of grading of absorption property, be applicable to that the judge of sanitary towels efficacy of adsorption detects.
2. test apparatus:
Glass exsiccator or 1000ml beaker, the extensive reagent paper of PH, triethylamine is analyzed alcohol, NH3 content 〉=99.0%
Adsorbent: (weak-type), sprinkling multi-efficiency healthy functions preparation sanitary towel.
3. test method
With range is that the liquid-transfering gun of 0-250uml is measured an amount of triethylamine (about 10-100uml according to circumstances decides) and directly dripped uptake zone, center in specimen, the test specimens that will be added with triethylamine is then rapidly put into the beaker of 1000ml with the preservative film sealing, presses down manual time-keeping simultaneously; Different time sections with extensive PH reagent paper (using the distilled water moistening in advance) test beaker in the pH value of air, observe PH reagent paper change in color after 5 minutes, judge the pH value of air in the beaker at this moment.Measured once every 30 minutes.Within 2 hours, when pH value≤8, decidable is that air does not have the amine flavor in the beaker.It is qualified promptly to be judged to.
4. test data sheet and scoring see the following form 8:
Table 8
Figure BSA00000290421700101
Illustrate: 1. above three time periods to the beaker of test adsorption function in the pH value of air;
2. provide scoring corresponding to PH, multiply by corresponding coefficient then, be the scoring of this time period;
3. when pH value≤8, with adding up of each time period scoring, the sum total that the efficacy of adsorption of final product was marked for each time period.
4. pass judgment on: it is low more to mark, and efficacy of adsorption is good more.Minimum as to be divided into 0.5 fen, adsorption effect is best; Higher assessment is divided into 17.5 fens, and adsorption effect is the poorest; Every in 2 hours, pH value≤8 o'clock, it is qualified to be judged to.Testing result sees the following form 9:
Table 9
Figure BSA00000290421700111
According to said method, added the product of example 3, mean ph value≤8, qualified two hours internal adsorption effects.
Example 4
Material name addition %
Bamboo extractive (dry distilling makes, effective ingredient 60%) 5
Flos Matricariae chamomillae (56% aqueous extract) 5
Aloe 5
HE 10
Propylene glycol 30
DP-300 0.3
DL 5
BZ 15
CO-40 2
Water 22.7
The main effect of product: have on the basis of submissive, skin protection, pass through to add bamboo extractive (the two Herba Asparagi Setacei leaf scientific and technological development company limiteies in Anji) in the prescription, the food stage peppermint ester, be that this product reaches certain weak acid performance, thereby use during the broiling summer, can bring salubrious, gas-pervious sensation to the women.
Treating excess syndrome example 4 products carry out following effect index verification.
Experiment condition: spray each 9 in back three kinds of samples, spray each 9 of back three kinds of sample plastic sealing packs, (54 ℃) calorstat is placed 14 days 1 year stability test under the sealing state.
1) weak acid effect checking:
The print of placement after 14 days launched respectively, inject the 10ml pH value then on the top layer and be 7.3 simulation menses, after 30 minutes, divide different time to test with accurate pH test paper to the surface, the results are shown in Figure 1: solid line is represented the excursion of pH value in 2 hours of common blank sanitary towel among the figure, and the excursion of pH value in 2 hours of the sanitary towel of example 4 products sprayed in the dotted line representative.Test result proves that on the print top layer of adding example 4 products, behind 30min, pH value is guaranteeing between 5-6, makes the sanitary towel top layer reach certain weak acid effect, is private portion environment for the women provides a safety and Health, and then avoids the growth of harmful bacterium.
2) refrigerant composition detection:
The product that sprayed example 4 is quickened 54 ℃ of accelerated aging tests of 7 days, and the refrigerant composition in testing product top layer is residual:
Chromatographic condition: chromatographic column: HP-LMS, 30mm, ф 0.25mm; Column temperature: 60 ℃ keep 60min, rise to 120 ℃ with 40 ℃/min, keep 5.5min, rise to 180 ℃ with 40 ℃/min, keep 6min.Injector temperature: 240 ℃.Detector temperature: 240 ℃.
Step: interior mark liquid: it is an amount of to take by weighing Ketohexamethylene, and adding normal hexane, to be mixed with concentration be 10mg/ml solution.
Reference substance solution: it is an amount of to take by weighing two kinds of reference substances, and mark liquid is an amount of in adding, and is mixed with the solution that every 1ml contains menthol, peppermint ester 1mg respectively, product solution in contrast with normal hexane.
Need testing solution: get the sanitary towel top layer, to the 50ml color comparison tube, the adding normal hexane is an amount of, and mark liquid is an amount of in adding, and mixing filters, and gets subsequent filtrate as need testing solution.
Measure: get above-mentioned reference substance solution and need testing solution 1 μ l sample introduction respectively, the record chromatogram.
Calculate: with the amount of internal standard method by every top layer menthol of calculated by peak area, peppermint ester.Testing result is seen Fig. 2, Fig. 3.
The residual ratio that example 4 products refrigerant composition in 7 days is sprayed in top lines representative in the accompanying drawing 2, the below lines are common blank sanitary towel, testing result proves, sprayed the sanitary towel of example 4, after the process accelerated aging test, the sanitary towel top layer still has refrigerant composition to exist, and can bring salubrious comfortable sensation to human body.
Fig. 3 is refrigerant composition (gas chromatogram of menthol, peppermint ester).The scope of application and addition see Table 12
Table 12:
Figure BSA00000290421700121
Added 18 ℃-28 ℃ of the product stock temperature of skin protectant.Dry, shady and cool, ventilate.
The Product transport temperature of adding skin protectant must not be higher than 54 ℃, prevents to be exposed to the sun.

Claims (7)

1. multi-efficiency skin care formulation compositions, raw material comprises: superfatting agent, antibacterial, natural plant extracts, adsorbent, salubrious agent, solvent is characterized in that its composition and quality proportioning are:
Superfatting agent 2%--20%
Antibacterial 0.3-10%
Natural plant extracts 5%--10%
Adsorbent 1%--10%
Salubrious agent 5%--20%
Flavouring agent 0.1%--10%
Antiseptic 0.1-0.3%
Solvent 20%--80.5%
Wherein, superfatting agent: water solublity Fructus Canarii albi grease, cocoyl glyceride, PEG-75, water solublity Semen Armeniacae Amarum grease, at least a;
Antibacterial: at least a in triclosan, chlorhexidine acetate, chlorhexidine gluconate, trichlorine kappa, benzalkonium chloride, benzalkonium bromide or the polyhexamethylene guanidine;
Natural plant extracts: at least a in Aloe polysaccharide extracting solution, willherb extract, Radix Arnebiae extract, green tea extract, camomile extract, Radix Hamamelidis Mollis extract, bamboo extractive or the Fructus Cucumidis sativi extract;
Adsorbent: at least a during cyclodextrin, organosilicon quaternary ammonium salt or Oleum Ricini are misery;
Salubrious agent: at least a in Borneolum Syntheticum, Oleum menthae, Oleum menthae, Mentholum, menthyl lactate, menthyl acetate, Herba Menthae glycerol ketals or the Herba Menthae glycerol acetonide ether;
Described additive is flavouring agent, antiseptic;
Solvent: at least a in propylene glycol, Macrogol 200, PEG400, Macrogol 600, castor oil hydrogenated or the water;
Described flavouring agent is essence or quintessence oil;
Described antiseptic is at least a in triclosan, Kazon, methyl hydroxybenzoate, propylparaben or the sodium benzoate.
2. multi-efficiency skin care formulation compositions, raw material comprises: superfatting agent, antibacterial, natural plant extracts, adsorbent, salubrious agent, solubilizing agent and solvent is characterized in that its quality group becomes:
Softener 2%-20%
Nourish composition 5%-10%
Antibacterial 0.3%-10%
Adsorbent 5%-10%
Salubrious agent 5%-20%
Solubilizing agent 5%-10%
Solvent 20%-80.5%
Softener be water solublity Fructus Canarii albi grease, cocoyl glyceride, PEG-75, water solublity Semen Armeniacae Amarum grease, at least a;
Nourish into component selections and use the Aloe polysaccharide extracting solution;
Antibacterial is DP300;
Adsorbent is a cyclodextrin;
The menthyl lactate that comprises highly purified menthol and low irritant in the salubrious agent, amide of mint;
Solubilizing agent is CO-40, propylene glycol;
Solvent is a deionized water.
3. according to the described multi-efficiency skin care formulation of claim 2 compositions, it is characterized in that described Aloe polysaccharide extracting solution is that concentration is 50% aloe water extract.
4. multi-efficiency skin care formulation compositions, the raw material that it is characterized in that it forms and the quality proportioning is:
Water solublity Fructus Canarii albi oils and fats 10%
Additive 1%
Propylene glycol 20%
Aloe extraction solution 5%
Water 64%
Additive is: at least a in Aloe essence, Aloe quintessence oil, triclosan, Kazon, methyl hydroxybenzoate, propylparaben or the sodium benzoate.
5. multi-efficiency skin care formulation compositions, the raw material that it is characterized in that it forms and the quality proportioning is:
Semen Armeniacae Amarum oils and fats 10%
Flos Matricariae chamomillae extracting solution 5%
Propylene glycol 20%
PEG400 10%
Triclosan 0.3%
Menthyl lactate 3%
Cyclodextrin 10%
Water 41.7%.
6. claim 1 or 2 multi-efficiency skin care formulation preparation of compositions methods, the step that comprises:
1) by measuring the solid material in the recipe ingredient, single grinding is respectively sieved, and it is stand-by to get 200-300 μ m;
2) by metering with superfatting agent, natural plant extracts, the antibacterial of recipe ingredient, fully mix with solvent and other auxiliary agents;
3) two kinds of components of above-mentioned steps are mixed, stir to clarify the transparent product that is.
7. the application of each described multi-efficiency skin care formulation compositions of claim 1-4 is characterized in that it is used to prepare sanitary towel, sanitary pad or diaper.
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CN103655330A (en) * 2014-01-23 2014-03-26 彭再辉 Men skin refreshing and nourishing emulsion and preparation method thereof
CN103816071A (en) * 2013-12-23 2014-05-28 青岛安信医疗器械有限公司 Skin lotion
CN105254775A (en) * 2015-11-11 2016-01-20 上海清轩生物科技有限公司 Aloe polysaccharide extracting method and aloe skin moistening composition
CN106800872A (en) * 2016-12-30 2017-06-06 福建恒安集团有限公司 Wink dry type hydrophilic nonwoven cloth top layer smears and disposable paper diaper
US9855203B2 (en) 2013-06-27 2018-01-02 The Procter & Gamble Company Preserving personal care compositions
CN109395145A (en) * 2018-12-05 2019-03-01 广东恒实业有限公司 A kind of paper diaper active peptides product and preparation method thereof
CN109414505A (en) * 2016-06-27 2019-03-01 尤妮佳股份有限公司 Warming piece
CN109512583A (en) * 2018-09-17 2019-03-26 杭州淑洁卫生用品有限公司 A kind of production method for the paper diaper preventing the red hip of infant
CN111773373A (en) * 2020-06-01 2020-10-16 杭州可靠护理用品股份有限公司 Hip-protecting preparation and application thereof in paper diapers

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CN101697951A (en) * 2009-10-28 2010-04-28 翁民辉 Protective liquid used for anal cleaning and use method thereof

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CN1522689A (en) * 2003-09-12 2004-08-25 周维海 Leech extract cosmetics and method for making same
CN101697951A (en) * 2009-10-28 2010-04-28 翁民辉 Protective liquid used for anal cleaning and use method thereof

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102371004A (en) * 2011-09-30 2012-03-14 天津市中科健新材料技术有限公司 Fragrant agent used for disposable sanitary products and preparation method of fragrant agent
US9855203B2 (en) 2013-06-27 2018-01-02 The Procter & Gamble Company Preserving personal care compositions
CN103816071A (en) * 2013-12-23 2014-05-28 青岛安信医疗器械有限公司 Skin lotion
CN103655330B (en) * 2014-01-23 2015-08-05 彭再辉 A kind of man wakes up skin moisturizer and preparation method thereof
CN103655330A (en) * 2014-01-23 2014-03-26 彭再辉 Men skin refreshing and nourishing emulsion and preparation method thereof
CN105254775A (en) * 2015-11-11 2016-01-20 上海清轩生物科技有限公司 Aloe polysaccharide extracting method and aloe skin moistening composition
CN105254775B (en) * 2015-11-11 2018-01-19 上海清轩生物科技有限公司 Aloe polysaccharide extraction method and aloe Sin-care composition
CN109414505A (en) * 2016-06-27 2019-03-01 尤妮佳股份有限公司 Warming piece
CN106800872A (en) * 2016-12-30 2017-06-06 福建恒安集团有限公司 Wink dry type hydrophilic nonwoven cloth top layer smears and disposable paper diaper
CN109512583A (en) * 2018-09-17 2019-03-26 杭州淑洁卫生用品有限公司 A kind of production method for the paper diaper preventing the red hip of infant
CN109395145A (en) * 2018-12-05 2019-03-01 广东恒实业有限公司 A kind of paper diaper active peptides product and preparation method thereof
CN111773373A (en) * 2020-06-01 2020-10-16 杭州可靠护理用品股份有限公司 Hip-protecting preparation and application thereof in paper diapers
CN111773373B (en) * 2020-06-01 2023-04-07 杭州可靠护理用品股份有限公司 Hip-protecting preparation and application thereof in paper diapers

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