CN101957354B - 包括串联的反应区的检验装置 - Google Patents

包括串联的反应区的检验装置 Download PDF

Info

Publication number
CN101957354B
CN101957354B CN201010250030.XA CN201010250030A CN101957354B CN 101957354 B CN101957354 B CN 101957354B CN 201010250030 A CN201010250030 A CN 201010250030A CN 101957354 B CN101957354 B CN 101957354B
Authority
CN
China
Prior art keywords
reaction zone
sample
response
analytical equipment
stream
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201010250030.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN101957354A (zh
Inventor
I·门德尔-哈特威格
G·伦德斯特伦
P·O·奥曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
J Remsen International Assets LLC
J&J JSC
Original Assignee
Amic AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43016565&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101957354(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amic AB filed Critical Amic AB
Publication of CN101957354A publication Critical patent/CN101957354A/zh
Application granted granted Critical
Publication of CN101957354B publication Critical patent/CN101957354B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16Reagents, handling or storing thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • B01L2300/126Paper
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0418Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CN201010250030.XA 2009-07-02 2010-07-02 包括串联的反应区的检验装置 Active CN101957354B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22286609P 2009-07-02 2009-07-02
US61/222,866 2009-07-02
SE0950518 2009-07-02
US61/222866 2009-07-02
SE0950518-1 2009-07-02

Publications (2)

Publication Number Publication Date
CN101957354A CN101957354A (zh) 2011-01-26
CN101957354B true CN101957354B (zh) 2015-04-01

Family

ID=43016565

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201010250030.XA Active CN101957354B (zh) 2009-07-02 2010-07-02 包括串联的反应区的检验装置

Country Status (6)

Country Link
US (1) US8409523B2 (fr)
EP (1) EP2269737B1 (fr)
CN (1) CN101957354B (fr)
BR (1) BRPI1002326A8 (fr)
CA (1) CA2708589C (fr)
RU (1) RU2538020C2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
EP2618153B1 (fr) * 2012-01-20 2015-03-18 Ortho-Clinical Diagnostics, Inc. Régulation d'écoulement de fluide à travers un dispositif de dosage
US9874556B2 (en) * 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
CA2841692C (fr) 2013-02-12 2023-08-22 Zhong Ding Motif de depot d'une zone d'agent reactif
JP5951527B2 (ja) 2013-03-07 2016-07-13 株式会社東芝 検体検出装置及び検出方法
JP2014173934A (ja) * 2013-03-07 2014-09-22 Toshiba Corp 半導体マイクロ分析チップ及びその製造方法
JP5904958B2 (ja) 2013-03-07 2016-04-20 株式会社東芝 半導体マイクロ分析チップ及びその製造方法
US9612203B2 (en) 2013-06-25 2017-04-04 National Tsing Hua University Detection device and manufacturing method for the same
JP6151128B2 (ja) 2013-08-12 2017-06-21 株式会社東芝 半導体マイクロ分析チップ及びその製造方法
CN108051590B (zh) 2013-09-13 2020-12-11 Symbolics有限责任公司 运用二维试验和对照信号读出模式的侧向层析检测
US10073091B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral flow assay device
CN112840210B (zh) * 2018-09-06 2024-09-06 澳科环球有限公司 用于确定分析物浓度的系统、传感器和方法
WO2024172849A2 (fr) 2022-05-13 2024-08-22 University Of Rochester Appareil de biocapteur photonique multiplex, système et procédés

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258548B1 (en) * 1997-06-05 2001-07-10 A-Fem Medical Corporation Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3973129A (en) 1975-01-10 1976-08-03 Bell Telephone Laboratories, Incorporated Fluorimetric apparatus and method for analysis of body fluid
US4956150A (en) 1985-11-27 1990-09-11 Alerchek Disposable microtiter stick
US5158720A (en) 1985-12-09 1992-10-27 Mcdonnell Douglas Corporation Method and system for continuous in situ monitoring of viscosity
US5051237A (en) 1988-06-23 1991-09-24 P B Diagnostic Systems, Inc. Liquid transport system
GB8827853D0 (en) 1988-11-29 1988-12-29 Ares Serono Res & Dev Ltd Sensor for optical assay
CA1337173C (fr) 1989-04-28 1995-10-03 Westaim Biomedical Corp. Dispositif a pellicule mince de detection de substances
GB9014903D0 (en) 1990-07-05 1990-08-22 Unilever Plc Assays
US5877028A (en) * 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5540888A (en) 1991-11-11 1996-07-30 British Technology Group Limited Liquid transfer assay devices
US6767510B1 (en) 1992-05-21 2004-07-27 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6905882B2 (en) 1992-05-21 2005-06-14 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6156270A (en) 1992-05-21 2000-12-05 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6143576A (en) 1992-05-21 2000-11-07 Biosite Diagnostics, Inc. Non-porous diagnostic devices for the controlled movement of reagents
US5885527A (en) 1992-05-21 1999-03-23 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membrances
US5427663A (en) 1993-06-08 1995-06-27 British Technology Group Usa Inc. Microlithographic array for macromolecule and cell fractionation
JPH07199236A (ja) 1993-12-28 1995-08-04 Fujitsu Ltd 光スイッチ及び光分配器
US5399499A (en) 1994-05-13 1995-03-21 Eastman Kodak Company Method of using multiwavelength upconversion for sample element interrogation in medical diagnostic equipment
US6391265B1 (en) 1996-08-26 2002-05-21 Biosite Diagnostics, Inc. Devices incorporating filters for filtering fluid samples
US6156273A (en) 1997-05-27 2000-12-05 Purdue Research Corporation Separation columns and methods for manufacturing the improved separation columns
US6368871B1 (en) 1997-08-13 2002-04-09 Cepheid Non-planar microstructures for manipulation of fluid samples
US6673629B2 (en) 1998-01-15 2004-01-06 Abbott Laboratories Neutralization of polycations in a chromatographic device for whole blood use
ATE442579T1 (de) 1998-02-05 2009-09-15 Novartis Erfind Verwalt Gmbh Verfahren und vorrichtung zur lumineszenzmessung
DE19810615A1 (de) 1998-03-12 1999-09-16 Thomas Ruckstuhl Optische Anordnung zum Erfassen von Licht
AU763497B2 (en) 1998-10-13 2003-07-24 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6416642B1 (en) 1999-01-21 2002-07-09 Caliper Technologies Corp. Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection
US6150178A (en) 1999-03-24 2000-11-21 Avitar, Inc. Diagnostic testing device
US6664104B2 (en) 1999-06-25 2003-12-16 Cepheid Device incorporating a microfluidic chip for separating analyte from a sample
ATE268642T1 (de) 1999-07-07 2004-06-15 3M Innovative Properties Co Nachweisgerät mit einer fluid-kontroll- filmschicht mit kapillarkanälen
US6762059B2 (en) 1999-08-13 2004-07-13 U.S. Genomics, Inc. Methods and apparatuses for characterization of single polymers
GB9924222D0 (en) 1999-10-14 1999-12-15 Imp College Innovations Ltd Assay device
US6451264B1 (en) 2000-01-28 2002-09-17 Roche Diagnostics Corporation Fluid flow control in curved capillary channels
WO2001057501A1 (fr) 2000-02-03 2001-08-09 Alpha Innotech Corporation Lecteur de jeux ordonnes de microechantillons ameliore
US20020004246A1 (en) 2000-02-07 2002-01-10 Daniels Robert H. Immunochromatographic methods for detecting an analyte in a sample which employ semiconductor nanocrystals as detectable labels
JP2003524193A (ja) 2000-02-23 2003-08-12 ザイオミックス インコーポレイテッド 高い位置に配置されたサンプル表面を有するチップ
US6436722B1 (en) 2000-04-18 2002-08-20 Idexx Laboratories, Inc. Device and method for integrated diagnostics with multiple independent flow paths
JP2002001102A (ja) 2000-06-20 2002-01-08 Kanagawa Acad Of Sci & Technol マイクロチャンネル構造
US20040126767A1 (en) 2002-12-27 2004-07-01 Biosite Incorporated Method and system for disease detection using marker combinations
EP1459068B1 (fr) * 2001-12-24 2010-08-18 Kimberly-Clark Worldwide, Inc. Syst me d' talonnage interne pour essai en coulement continu
DE10220296A1 (de) * 2002-05-07 2003-11-20 Roche Diagnostics Gmbh Vorrichtung zur Probennahme von flüssigen Proben
SE0201738D0 (sv) * 2002-06-07 2002-06-07 Aamic Ab Micro-fluid structures
ES2341103T3 (es) 2002-10-23 2010-06-15 The Trustees Of Princeton University Procedimiento de separacion continua de particulas usando reticulados de obstaculos alineados asimetricamente respecto a campos.
AU2003302254A1 (en) 2002-12-16 2004-07-22 Avery Dennison Corporation Analyte detecting article and method
US20040191127A1 (en) 2003-03-31 2004-09-30 Avinoam Kornblit Method and apparatus for controlling the movement of a liquid on a nanostructured or microstructured surface
SE0400662D0 (sv) 2004-03-24 2004-03-24 Aamic Ab Assay device and method
SE527036C2 (sv) 2004-06-02 2005-12-13 Aamic Ab Analysanordning med reglerat flöde och motsvarande förfarande
EP1891753A1 (fr) 2005-06-15 2008-02-27 Telefonaktiebolaget LM Ericsson (publ) Procede et moyens permettant de limiter les pics d'interference pendant un transfert souple
US20080099331A1 (en) * 2006-01-12 2008-05-01 Chung Yuan Christian University Solid-state urea biosensor and its data acquisition system
US7695687B2 (en) * 2006-06-30 2010-04-13 International Business Machines Corporation Capillary system for controlling the flow rate of fluids
CN101754812B (zh) 2007-05-04 2013-06-26 克拉洛诊断仪器公司 流体连接器和微流体系统

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258548B1 (en) * 1997-06-05 2001-07-10 A-Fem Medical Corporation Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules

Also Published As

Publication number Publication date
EP2269737A2 (fr) 2011-01-05
US20110003398A1 (en) 2011-01-06
EP2269737A3 (fr) 2013-06-05
CA2708589A1 (fr) 2011-01-02
CA2708589C (fr) 2017-04-25
US8409523B2 (en) 2013-04-02
RU2010127054A (ru) 2012-01-10
BRPI1002326A2 (pt) 2012-02-22
EP2269737B1 (fr) 2017-09-13
BRPI1002326A8 (pt) 2018-02-27
CN101957354A (zh) 2011-01-26
RU2538020C2 (ru) 2015-01-10

Similar Documents

Publication Publication Date Title
CN101957354B (zh) 包括串联的反应区的检验装置
EP2460004B1 (fr) Analyse de comportement de phase au moyen d'une plate-forme microfluidique
US10620102B2 (en) Viscosity measurements based on tracer diffusion
AU2012264410B2 (en) Capillary fluid flow measurment and capillary flow device therefore
KR20110080067A (ko) 샘플분석 카트리지 및 샘플분석 카트리지 리더
Thangawng et al. A hard microflow cytometer using groove-generated sheath flow for multiplexed bead and cell assays
EP3239720B1 (fr) Appareil permettant de mesurer la vitesse d'un fluide
WO2010007210A1 (fr) Procédé et appareil pour contrôler l'écoulement d'un fluide dans un système microfluidique
Kong et al. Label-free counting of affinity-enriched circulating tumor cells (CTCs) using a thermoplastic micro-C oulter counter (μCC)
KR101605653B1 (ko) 유체 속도 측정 장치
KR20230054407A (ko) 성분분석용 h-형 필터장치
JP7520053B2 (ja) ライン体積較正システムと方法
EP3025781B1 (fr) Procédé permettant de déterminer une agglutination
KR101635510B1 (ko) 적혈구 멤브레인의 슬립현상에 의한 속도차이 계측용 직렬형 랩온어칩 장치 및 그 광계측 시스템
EP3239721B1 (fr) Appareil de mesure de vitesse de fluide
US8845981B2 (en) Biologic fluid analysis cartridge with volumetric sample metering
KR101033206B1 (ko) 타겟 포획을 위한 미세 유체 채널과 미세 유체 장치 및 이를 포함하는 미세 유체 분석 시스템
JP4833228B2 (ja) 溶液自動供給装置
Yamaguchi et al. White Blood Cell Counting Device for Dairy Cattle Using Microchannel Incorporating Light Scattering
RU2012140371A (ru) Способ определения маркера в малом объеме образца биологической жидкости

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20180718

Address after: Delaware

Patentee after: J Remsen international assets LLC

Address before: Solna, Sweden

Patentee before: J&J JSC

Effective date of registration: 20180718

Address after: Solna, Sweden

Patentee after: J&J JSC

Address before: uppsala

Patentee before: AMIC AB

TR01 Transfer of patent right