CN101821627A - 免疫原性链球菌蛋白质 - Google Patents

免疫原性链球菌蛋白质 Download PDF

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Publication number
CN101821627A
CN101821627A CN200880110303A CN200880110303A CN101821627A CN 101821627 A CN101821627 A CN 101821627A CN 200880110303 A CN200880110303 A CN 200880110303A CN 200880110303 A CN200880110303 A CN 200880110303A CN 101821627 A CN101821627 A CN 101821627A
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China
Prior art keywords
streptococcus
albumen
protein
strains
kinds
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Pending
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CN200880110303A
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English (en)
Chinese (zh)
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希尔达·E·史密斯
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Boehringer Ingelheim Vetmedica GmbH
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Boehringer Ingelheim Vetmedica GmbH
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Application filed by Boehringer Ingelheim Vetmedica GmbH filed Critical Boehringer Ingelheim Vetmedica GmbH
Publication of CN101821627A publication Critical patent/CN101821627A/zh
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56944Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Communicable Diseases (AREA)
  • Pregnancy & Childbirth (AREA)
CN200880110303A 2007-08-06 2008-08-05 免疫原性链球菌蛋白质 Pending CN101821627A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07113844.0 2007-08-06
EP07113844A EP2023143A1 (en) 2007-08-06 2007-08-06 Immunogenic streptococcus proteins
PCT/NL2008/050537 WO2009020391A1 (en) 2007-08-06 2008-08-05 Immunogenic streptococcus proteins

Publications (1)

Publication Number Publication Date
CN101821627A true CN101821627A (zh) 2010-09-01

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ID=38890252

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880110303A Pending CN101821627A (zh) 2007-08-06 2008-08-05 免疫原性链球菌蛋白质

Country Status (19)

Country Link
US (1) US20100297183A1 (enExample)
EP (3) EP2023143A1 (enExample)
JP (2) JP5462164B2 (enExample)
KR (1) KR20100063706A (enExample)
CN (1) CN101821627A (enExample)
AR (1) AR067830A1 (enExample)
AU (1) AU2008284491A1 (enExample)
BR (1) BRPI0815604A2 (enExample)
CA (1) CA2695721A1 (enExample)
CL (1) CL2008002320A1 (enExample)
CO (1) CO6270172A2 (enExample)
DK (1) DK2183597T3 (enExample)
ES (1) ES2432407T3 (enExample)
MX (1) MX2010001482A (enExample)
RU (1) RU2518315C2 (enExample)
TW (1) TW200911999A (enExample)
UA (1) UA103885C2 (enExample)
WO (1) WO2009020391A1 (enExample)
ZA (1) ZA201000806B (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102209555A (zh) * 2008-10-06 2011-10-05 诺丁汉大学 含有分选酶锚定乳房链球菌表面蛋白的组合物
CN107108756A (zh) * 2014-12-22 2017-08-29 豪夫迈·罗氏有限公司 细胞穿透性肽
CN108135992A (zh) * 2015-10-21 2018-06-08 米纳瓦克斯有限责任公司 免疫原性融合蛋白
CN119780429A (zh) * 2024-12-27 2025-04-08 华派生物技术(集团)股份有限公司 一种提高猪圆环病毒2型Cap蛋白抗原琼扩检测灵敏度的方法
CN119780429B (zh) * 2024-12-27 2025-12-26 华派生物技术(集团)股份有限公司 一种提高猪圆环病毒2型Cap蛋白抗原琼扩检测灵敏度的方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL204863B1 (pl) 1998-07-22 2010-02-26 Stichting Dienst Landbouwkundi Zastosowanie mutanta Streptococcus, szczepionka i sposoby kontrolowania lub eliminowania choroby paciorkowcowej w populacji
AU2002230275A1 (en) * 2001-02-02 2002-08-12 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Environmentally regulated genes, involved in the virulence ofstreptococcus suis
WO2015042369A2 (en) 2013-09-19 2015-03-26 Zoetis Llc Oil-based adjuvants
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
RU2685957C2 (ru) * 2016-12-28 2019-04-23 Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") Химерный рекомбинантный белок, обладающий протективными свойствами в отношении Streptococcus pyogenes
US20240024380A1 (en) * 2020-12-23 2024-01-25 Chan Zuckerberg Biohub, Inc. Bacteria-engineered to elicit antigen-specific t cells
CN112773891B (zh) * 2021-02-01 2022-03-25 北部湾大学 卵形鲳鲹源无乳链球菌dna疫苗及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000037105A2 (en) * 1998-12-21 2000-06-29 Medimmune, Inc. Streptococcus pneumoniae proteins and immunogenic fragments for vaccines

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283507A (en) 1990-12-20 1994-02-01 General Electric Company Regenerative braking protection for an electrically-propelled traction vehicle
NL9100510A (nl) * 1991-03-21 1992-10-16 Centraal Diergeneeskundig Inst Dna-sequenties die coderen voor kenmerken van virulentie van streptococcus suis en delen daarvan, daarvan afgeleide polypeptiden en antilichamen, alsmede toepassing daarvan bij de diagnose van en de bescherming tegen infectie met s. suis bij zoogdieren, waaronder de mens.
IT1251435B (it) 1991-09-04 1995-05-09 Sclavo Spa Vettore genetico per la integrazione multipla stabile di sequenze di dna nel genoma dei lieviti kluyveromyces lactis e saccharomyces cerevisiae e plasmidi che lo contengono.
US5928900A (en) * 1993-09-01 1999-07-27 The Rockefeller University Bacterial exported proteins and acellular vaccines based thereon
EP0804582A1 (en) * 1994-05-16 1997-11-05 The Uab Research Foundation $i(STREPTOCOCCUS PNEUMONIAE) CAPSULAR POLYSACCHARIDE GENES AND FLANKING REGIONS
US5681570A (en) * 1995-01-12 1997-10-28 Connaught Laboratories Limited Immunogenic conjugate molecules
EP0750042A1 (fr) * 1995-06-20 1996-12-27 Societe Des Produits Nestle S.A. Bactéries lactiques produisant des exopolysaccharides
PT900380E (pt) 1996-04-26 2003-12-31 Univ Leiden Metodos para seleccionar e produzir epitopos peptidicos de celulas t e vacinas que incorporam os referidos epitopos seleccionados
US6800744B1 (en) * 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
PL204863B1 (pl) * 1998-07-22 2010-02-26 Stichting Dienst Landbouwkundi Zastosowanie mutanta Streptococcus, szczepionka i sposoby kontrolowania lub eliminowania choroby paciorkowcowej w populacji
ATE405636T1 (de) * 1999-06-16 2008-09-15 Boston Biomedical Res Inst Immunologische kontrolle des beta-amyloid gehaltes in vivo
PT1294771E (pt) * 2000-06-12 2009-01-06 Univ Saskatchewan Proteína gapc quimérica de streptococcus e sua utilização em vacinação e diagnóstico
EP1205552A1 (en) * 2000-11-09 2002-05-15 ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. Virulence of streptococci, involving ORFs from Streptococcus suis
AU2002230275A1 (en) * 2001-02-02 2002-08-12 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Environmentally regulated genes, involved in the virulence ofstreptococcus suis
US7517955B2 (en) * 2002-11-26 2009-04-14 University Of Tennessee Research Foundation Streptococcus uberis adhesion molecule
WO2004067559A1 (en) * 2003-01-27 2004-08-12 Københavns Universitet Compounds useful in the diagnosis and treatment of pregnancy-associated malaria
CA2525540A1 (en) * 2003-05-30 2004-12-09 Intercell Ag Enterococcus antigens
WO2006048763A1 (en) * 2004-11-05 2006-05-11 Pharmacia & Upjohn Company Llc Anti-bacterial vaccine compositions
PT2029173T (pt) * 2006-06-26 2016-11-02 Macrogenics Inc Anticorpos específicos fc rib e seus métodos de uso

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000037105A2 (en) * 1998-12-21 2000-06-29 Medimmune, Inc. Streptococcus pneumoniae proteins and immunogenic fragments for vaccines

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102209555A (zh) * 2008-10-06 2011-10-05 诺丁汉大学 含有分选酶锚定乳房链球菌表面蛋白的组合物
CN107108756A (zh) * 2014-12-22 2017-08-29 豪夫迈·罗氏有限公司 细胞穿透性肽
CN108135992A (zh) * 2015-10-21 2018-06-08 米纳瓦克斯有限责任公司 免疫原性融合蛋白
US11325950B2 (en) 2015-10-21 2022-05-10 Minervax Aps Immunogenic fusion protein
US12173033B2 (en) 2015-10-21 2024-12-24 Minervax Aps Immunogenic fusion protein
CN119780429A (zh) * 2024-12-27 2025-04-08 华派生物技术(集团)股份有限公司 一种提高猪圆环病毒2型Cap蛋白抗原琼扩检测灵敏度的方法
CN119780429B (zh) * 2024-12-27 2025-12-26 华派生物技术(集团)股份有限公司 一种提高猪圆环病毒2型Cap蛋白抗原琼扩检测灵敏度的方法

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Publication number Publication date
MX2010001482A (es) 2010-03-01
ES2432407T3 (es) 2013-12-03
TW200911999A (en) 2009-03-16
BRPI0815604A2 (pt) 2015-03-03
JP2010535500A (ja) 2010-11-25
JP2014095721A (ja) 2014-05-22
CO6270172A2 (es) 2011-04-20
EP2183597B1 (en) 2013-07-24
EP2660604A2 (en) 2013-11-06
US20100297183A1 (en) 2010-11-25
AR067830A1 (es) 2009-10-21
KR20100063706A (ko) 2010-06-11
CA2695721A1 (en) 2009-02-12
ZA201000806B (en) 2010-10-27
AU2008284491A1 (en) 2009-02-12
RU2518315C2 (ru) 2014-06-10
CL2008002320A1 (es) 2009-09-25
EP2183597A1 (en) 2010-05-12
JP5462164B2 (ja) 2014-04-02
RU2010107878A (ru) 2011-09-20
EP2660604A3 (en) 2014-02-12
UA103885C2 (en) 2013-12-10
EP2023143A1 (en) 2009-02-11
WO2009020391A1 (en) 2009-02-12
DK2183597T3 (da) 2013-10-14

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Application publication date: 20100901