CN101802180B - 真菌过氧合酶和应用方法 - Google Patents
真菌过氧合酶和应用方法 Download PDFInfo
- Publication number
- CN101802180B CN101802180B CN200880017970.5A CN200880017970A CN101802180B CN 101802180 B CN101802180 B CN 101802180B CN 200880017970 A CN200880017970 A CN 200880017970A CN 101802180 B CN101802180 B CN 101802180B
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- China
- Prior art keywords
- seq
- gly
- pro
- leu
- ala
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Detergent Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007016139A DE102007016139A1 (de) | 2007-03-30 | 2007-03-30 | Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen |
| DE102007016139.7 | 2007-03-30 | ||
| PCT/EP2008/053798 WO2008119780A2 (en) | 2007-03-30 | 2008-03-31 | Fungal peroxygenases and methods of application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101802180A CN101802180A (zh) | 2010-08-11 |
| CN101802180B true CN101802180B (zh) | 2017-04-05 |
Family
ID=39591196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200880017970.5A Expired - Fee Related CN101802180B (zh) | 2007-03-30 | 2008-03-31 | 真菌过氧合酶和应用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8367387B2 (enExample) |
| EP (3) | EP2471911A3 (enExample) |
| JP (2) | JP5411121B2 (enExample) |
| CN (1) | CN101802180B (enExample) |
| AT (1) | ATE548449T1 (enExample) |
| CA (1) | CA2682451C (enExample) |
| DE (1) | DE102007016139A1 (enExample) |
| DK (1) | DK2158313T3 (enExample) |
| WO (1) | WO2008119780A2 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2553109B1 (en) | 2010-03-28 | 2018-10-24 | Novozymes A/S | Regioselective hydroxylation of aliphatic hydrocarbons employing a fungal peroxygenase |
| WO2013004639A2 (en) | 2011-07-07 | 2013-01-10 | Novozymes A/S | Enzymatic preparation of diols |
| WO2013021064A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| US9382559B2 (en) | 2011-08-10 | 2016-07-05 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021060A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021062A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021065A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021059A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| US9487761B2 (en) | 2011-08-10 | 2016-11-08 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013079531A2 (en) | 2011-12-02 | 2013-06-06 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| US9404093B2 (en) | 2011-12-02 | 2016-08-02 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| JP2015516804A (ja) | 2012-03-31 | 2015-06-18 | ノボザイムス アクティーゼルスカブ | ペルオキシゲナーゼを用いたエポキシ化 |
| PT2875179T (pt) | 2012-07-18 | 2018-04-23 | Novozymes As | Resumo |
| US20150152452A1 (en) | 2012-07-20 | 2015-06-04 | Novozymes A/S | Enzymatic Oxidation of 5-Hydroxymethylfurfural and Derivatives Thereof |
| CN104718287B (zh) * | 2012-10-12 | 2018-02-06 | 诺维信公司 | 具有过氧合酶活性的多肽 |
| WO2014056927A2 (en) | 2012-10-12 | 2014-04-17 | Novozymes A/S | Polypeptides having peroxygenase activity |
| WO2014056922A2 (en) | 2012-10-12 | 2014-04-17 | Novozymes A/S | Polypeptides having peroxygenase activity |
| WO2014056920A2 (en) | 2012-10-12 | 2014-04-17 | Novozymes A/S | Polypeptides having peroxygenase activity |
| CN104704116B (zh) * | 2012-10-12 | 2018-09-28 | 诺维信公司 | 具有过氧合酶活性的多肽 |
| US9499802B2 (en) | 2012-10-12 | 2016-11-22 | Novozymes A/S | Polypeptides having peroxygenase activity |
| US9458435B2 (en) | 2012-10-12 | 2016-10-04 | Novozymes A/S | Polypeptides having peroxygenase activity |
| EP2906685B1 (en) | 2012-10-12 | 2018-08-15 | Novozymes A/S | Polypeptides having peroxygenase activity |
| WO2014090940A1 (en) * | 2012-12-14 | 2014-06-19 | Novozymes A/S | Removal of skin-derived body soils |
| EP2871233A1 (de) | 2013-11-12 | 2015-05-13 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur Herstellung von biogenen Stoffen |
| JP6291051B2 (ja) * | 2013-11-18 | 2018-03-14 | エンザイマティック デインキング テクノロジーズ, エルエルシー | 製紙用バージン繊維及び再生紙の残存鉱油濃度低減のための酵素処理 |
| US10465172B2 (en) | 2013-11-29 | 2019-11-05 | Novozymes A/S | Peroxygenase variants |
| WO2016207373A1 (en) | 2015-06-26 | 2016-12-29 | Novozymes A/S | Polypeptides having peroxygenase activity |
| ES2869296T3 (es) | 2017-04-20 | 2021-10-25 | Consejo Superior Investigacion | Proceso para acortar la cadena hidrocarbonada de un ácido carboxílico mediante una peroxidasa |
| NL2021113B1 (en) | 2018-06-13 | 2019-12-19 | Univ Delft Tech | Synthesis of aromatic epoxide derived compounds |
| US11866757B2 (en) | 2018-07-03 | 2024-01-09 | Ruhr-Universitaet Bochum | Plasma-driven biocatalysis |
| EP3594332A1 (en) * | 2018-07-10 | 2020-01-15 | Consejo Superior de Investigaciones Cientificas | Method of heterologous expression of active fungal unspecific peroxygenase in bacterial host cells for fatty-acid epoxidation and other oxygenation reactions |
| EP3660147A1 (en) | 2018-11-30 | 2020-06-03 | Consejo Superior de Investigaciones Cientificas (CSIC) | Process for selective synthesis of 4-hydroxyisophorone and 4-ketoisophorone by fungal peroxygenases |
| US20220064516A1 (en) * | 2019-01-03 | 2022-03-03 | Locus Oil Ip Company, Llc | Materials and Methods for Extended Reduction of Heavy Crude Oil Viscosity |
| CN114641565B (zh) | 2019-07-05 | 2024-10-22 | 比西有限公司 | 重组血红素硫醇盐加氧酶 |
| US20240010996A1 (en) | 2020-09-23 | 2024-01-11 | Gecco Biotech B.V. | Bacterial unspecific peroxygenases (BUPO's) and methods and uses thereof |
| DE102021204094A1 (de) | 2021-04-25 | 2022-10-27 | Brandenburgische Technische Universität Cottbus-Senftenberg | In-vitro Arzneimittel aus Prodrugs und deren Verwendung |
| DE102021209758A1 (de) | 2021-09-03 | 2023-03-09 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur zellfreien Herstellung von unspezifischen Peroxygenasen und deren Verwendung |
| DE102021214582A1 (de) | 2021-12-17 | 2023-06-22 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur zellfreien Herstellung von unspezifischen Peroxygenasen und deren Verwendung |
| EP4396194A1 (de) | 2021-09-03 | 2024-07-10 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur zellfreien herstellung von unspezifischen peroxygenasen |
| CN116240246B (zh) * | 2021-12-20 | 2025-01-21 | 浙江金朗博药业有限公司 | 利用过氧化物酶合成骨化二醇的方法 |
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-
2007
- 2007-03-30 DE DE102007016139A patent/DE102007016139A1/de not_active Withdrawn
-
2008
- 2008-03-31 WO PCT/EP2008/053798 patent/WO2008119780A2/en not_active Ceased
- 2008-03-31 EP EP12161074A patent/EP2471911A3/en not_active Withdrawn
- 2008-03-31 CN CN200880017970.5A patent/CN101802180B/zh not_active Expired - Fee Related
- 2008-03-31 DK DK08718350.5T patent/DK2158313T3/da active
- 2008-03-31 EP EP12158017.9A patent/EP2468852B1/en not_active Not-in-force
- 2008-03-31 CA CA2682451A patent/CA2682451C/en not_active Expired - Fee Related
- 2008-03-31 US US12/532,870 patent/US8367387B2/en not_active Expired - Fee Related
- 2008-03-31 AT AT08718350T patent/ATE548449T1/de active
- 2008-03-31 JP JP2010500298A patent/JP5411121B2/ja not_active Expired - Fee Related
- 2008-03-31 EP EP08718350A patent/EP2158313B1/en not_active Not-in-force
-
2012
- 2012-12-20 US US13/722,019 patent/US20130115662A1/en not_active Abandoned
-
2013
- 2013-08-21 JP JP2013171739A patent/JP2014000086A/ja active Pending
Non-Patent Citations (3)
| Title |
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| Martin Hofrichter和René Ullrich.Heme-thiolate haloperoxidases versatile biocatalysts with biotechnological and environmental significance.《Applied Microbiology and Biotechnology》.2006,第71卷(第3期),276-288. * |
| Rene´Ullrich等.Novel Haloperoxidase from the Agaric Basidiomycete Agrocybe aegerita Oxidizes Aryl Alcohols and Aldehydes.《APPLIED AND ENVIRONMENTAL MICROBIOLOGY》.2004,第70卷(第8期),4575-4581. * |
| Ullrich和Martin Hofrichter.The haloperoxidase of the agaric fungus Agrocybe aegerita hydroxylates toluene and naphthalene.《FEBS Letters》.2005,第579卷(第27期),6247-6250. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2682451A1 (en) | 2008-10-09 |
| CA2682451C (en) | 2015-11-24 |
| US20130115662A1 (en) | 2013-05-09 |
| JP2010523079A (ja) | 2010-07-15 |
| EP2471911A2 (en) | 2012-07-04 |
| EP2158313A2 (en) | 2010-03-03 |
| CN101802180A (zh) | 2010-08-11 |
| US8367387B2 (en) | 2013-02-05 |
| EP2158313B1 (en) | 2012-03-07 |
| JP2014000086A (ja) | 2014-01-09 |
| EP2471911A3 (en) | 2012-12-12 |
| DK2158313T3 (da) | 2012-05-14 |
| US20100279366A1 (en) | 2010-11-04 |
| EP2468852A1 (en) | 2012-06-27 |
| EP2468852B1 (en) | 2014-07-16 |
| WO2008119780A2 (en) | 2008-10-09 |
| JP5411121B2 (ja) | 2014-02-12 |
| DE102007016139A1 (de) | 2008-10-02 |
| WO2008119780A3 (en) | 2009-03-12 |
| ATE548449T1 (de) | 2012-03-15 |
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