CN101759882A - 交联葡聚糖磁性复合微粒及其制备方法及其使用 - Google Patents
交联葡聚糖磁性复合微粒及其制备方法及其使用 Download PDFInfo
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- CN101759882A CN101759882A CN200810236462A CN200810236462A CN101759882A CN 101759882 A CN101759882 A CN 101759882A CN 200810236462 A CN200810236462 A CN 200810236462A CN 200810236462 A CN200810236462 A CN 200810236462A CN 101759882 A CN101759882 A CN 101759882A
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- composite particles
- sephadex
- magnetic
- magnetic composite
- dextran
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
- H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
- H01F1/01—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials
- H01F1/03—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity
- H01F1/032—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials
- H01F1/04—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials metals or alloys
- H01F1/06—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials metals or alloys in the form of particles, e.g. powder
- H01F1/08—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials metals or alloys in the form of particles, e.g. powder pressed, sintered, or bound together
- H01F1/083—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials metals or alloys in the form of particles, e.g. powder pressed, sintered, or bound together in a bonding agent
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Power Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (13)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2008102364628A CN101759882B (zh) | 2008-12-25 | 2008-12-25 | 交联葡聚糖磁性复合微粒及其制备方法及其使用 |
PCT/CN2008/002097 WO2010072018A1 (zh) | 2008-12-25 | 2008-12-29 | 交联葡聚糖磁性复合微粒及其制备方法及其使用 |
US13/142,159 US20120003321A1 (en) | 2008-12-25 | 2008-12-29 | Crosslinked Dextran Composite Magnetic Microparticles and Preparation Process and Using Method Thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2008102364628A CN101759882B (zh) | 2008-12-25 | 2008-12-25 | 交联葡聚糖磁性复合微粒及其制备方法及其使用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101759882A true CN101759882A (zh) | 2010-06-30 |
CN101759882B CN101759882B (zh) | 2012-02-29 |
Family
ID=42286841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2008102364628A Active CN101759882B (zh) | 2008-12-25 | 2008-12-25 | 交联葡聚糖磁性复合微粒及其制备方法及其使用 |
Country Status (3)
Country | Link |
---|---|
US (1) | US20120003321A1 (zh) |
CN (1) | CN101759882B (zh) |
WO (1) | WO2010072018A1 (zh) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103990440A (zh) * | 2014-05-13 | 2014-08-20 | 武汉汇研生物科技有限公司 | 一种葡聚糖生物分离纯化介质的制备方法 |
CN104258399A (zh) * | 2014-09-25 | 2015-01-07 | 西南交通大学 | 一种结晶有机小分子原位诱导磁性粒子制备印迹纳米磁球的方法 |
CN104693473A (zh) * | 2013-12-05 | 2015-06-10 | 天津大学 | 一种重复载药微球及其制备方法 |
CN105478087A (zh) * | 2016-01-06 | 2016-04-13 | 郑州英诺生物科技有限公司 | 一种基于涂覆葡聚糖的羧基磁珠的制备方法及其应用 |
CN106268692A (zh) * | 2016-09-07 | 2017-01-04 | 济南大学 | 聚环氧氯丙烷二甲胺修饰多孔磁性葡聚糖微球制备方法 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110218123A1 (en) | 2008-09-19 | 2011-09-08 | President And Fellows Of Harvard College | Creation of libraries of droplets and related species |
WO2010075639A1 (zh) | 2008-12-31 | 2010-07-08 | 陕西北美基因股份有限公司 | 四氧化三铁磁性纳米微球的制备方法 |
US20160279068A1 (en) * | 2013-11-08 | 2016-09-29 | President And Fellows Of Harvard College | Microparticles, methods for their preparation and use |
JP6188743B2 (ja) * | 2014-06-19 | 2017-08-30 | キヤノン株式会社 | 複数の光学機能面を有する光学素子、分光装置およびその製造方法 |
CN108289797B (zh) | 2015-10-13 | 2022-01-28 | 哈佛学院院长及董事 | 用于制备和使用凝胶微球的系统和方法 |
GB2543604A (en) * | 2016-07-20 | 2017-04-26 | Ubicoat Ltd | Production of nanoscale powders of embedded nanoparticles |
EP3583136B1 (en) * | 2017-02-16 | 2022-08-31 | Nutrition & Biosciences USA 4, Inc. | Crosslinked dextran and crosslinked dextran-poly alpha-1,3-glucan graft copolymers |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3002823A (en) * | 1958-04-16 | 1961-10-03 | Pharmacia Ab | Process of separating materials having different molecular weights and dimensions |
NL252506A (zh) * | 1959-06-12 | |||
US4452773A (en) * | 1982-04-05 | 1984-06-05 | Canadian Patents And Development Limited | Magnetic iron-dextran microspheres |
US4770183A (en) * | 1986-07-03 | 1988-09-13 | Advanced Magnetics Incorporated | Biologically degradable superparamagnetic particles for use as nuclear magnetic resonance imaging agents |
US5262176A (en) * | 1986-07-03 | 1993-11-16 | Advanced Magnetics, Inc. | Synthesis of polysaccharide covered superparamagnetic oxide colloids |
SE8704158L (sv) * | 1987-10-26 | 1989-04-27 | Carbomatrix Ab C O Ulf Schroed | Mikrosfaerer, foerfarande foer framstaellning daerav och anvaendning daerav |
US5411730A (en) * | 1993-07-20 | 1995-05-02 | Research Corporation Technologies, Inc. | Magnetic microparticles |
US20040146855A1 (en) * | 2003-01-27 | 2004-07-29 | Marchessault Robert H. | Formation of superparamagnetic particles |
CN100461310C (zh) * | 2005-10-14 | 2009-02-11 | 华东师范大学 | 双功能磁流体及其制备方法 |
CN101062416A (zh) * | 2006-12-18 | 2007-10-31 | 华中科技大学同济医学院附属协和医院 | 葡聚糖四氧化三铁磁性纳米材料及其制备方法和应用 |
CN101012312A (zh) * | 2007-02-08 | 2007-08-08 | 上海交通大学 | 多功能高分子-无机复合微球的制备方法 |
CN100593545C (zh) * | 2007-10-23 | 2010-03-10 | 北京博迈世纪生物技术有限公司 | 一种免疫纳米磁性葡聚糖微球的制备方法 |
-
2008
- 2008-12-25 CN CN2008102364628A patent/CN101759882B/zh active Active
- 2008-12-29 WO PCT/CN2008/002097 patent/WO2010072018A1/zh active Application Filing
- 2008-12-29 US US13/142,159 patent/US20120003321A1/en not_active Abandoned
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104693473A (zh) * | 2013-12-05 | 2015-06-10 | 天津大学 | 一种重复载药微球及其制备方法 |
CN103990440A (zh) * | 2014-05-13 | 2014-08-20 | 武汉汇研生物科技有限公司 | 一种葡聚糖生物分离纯化介质的制备方法 |
CN104258399A (zh) * | 2014-09-25 | 2015-01-07 | 西南交通大学 | 一种结晶有机小分子原位诱导磁性粒子制备印迹纳米磁球的方法 |
CN104258399B (zh) * | 2014-09-25 | 2016-10-05 | 西南交通大学 | 一种结晶有机小分子原位诱导磁性粒子制备印迹纳米磁球的方法 |
CN105478087A (zh) * | 2016-01-06 | 2016-04-13 | 郑州英诺生物科技有限公司 | 一种基于涂覆葡聚糖的羧基磁珠的制备方法及其应用 |
CN106268692A (zh) * | 2016-09-07 | 2017-01-04 | 济南大学 | 聚环氧氯丙烷二甲胺修饰多孔磁性葡聚糖微球制备方法 |
CN106268692B (zh) * | 2016-09-07 | 2018-05-29 | 济南大学 | 聚环氧氯丙烷二甲胺修饰多孔磁性葡聚糖微球制备方法 |
Also Published As
Publication number | Publication date |
---|---|
US20120003321A1 (en) | 2012-01-05 |
WO2010072018A1 (zh) | 2010-07-01 |
CN101759882B (zh) | 2012-02-29 |
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C14 | Grant of patent or utility model | ||
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ASS | Succession or assignment of patent right |
Owner name: XI AN GOLDMAG NANOBIOTECH CO., LTD. Free format text: FORMER OWNER: SHAANXI BAIMEI GENE CO., LTD. Effective date: 20130718 |
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C41 | Transfer of patent application or patent right or utility model | ||
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Owner name: SHAANXI BAIMEI GENE CO., LTD. Free format text: FORMER NAME: SHAANXI LIFEGEN CO., LTD. |
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COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 710069 XI AN, SHAANXI PROVINCE TO: 710077 XI AN, SHAANXI PROVINCE |
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CP01 | Change in the name or title of a patent holder |
Address after: 710069 No. 386, 229 Taibai Road, Shaanxi, Xi'an, China Patentee after: SHAANXI LIFEGEN Co.,Ltd. Address before: 710069 No. 386, 229 Taibai Road, Shaanxi, Xi'an, China Patentee before: Shaanxi North American Gene Co.,Ltd. |
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TR01 | Transfer of patent right |
Effective date of registration: 20130718 Address after: 710077, Shaanxi, Xi'an hi tech Zone, No. 85, No. 4, No. 2, modern enterprise center, 3 east side, 10402A Patentee after: XI'AN GOLDMAG NANOBIOTECH Co.,Ltd. Address before: 710069 No. 386, 229 Taibai Road, Shaanxi, Xi'an, China Patentee before: SHAANXI LIFEGEN Co.,Ltd. |