CN101744245A - Soft capsule of royal jelly and schisandra fruit and preparation method thereof - Google Patents
Soft capsule of royal jelly and schisandra fruit and preparation method thereof Download PDFInfo
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- CN101744245A CN101744245A CN200810209694A CN200810209694A CN101744245A CN 101744245 A CN101744245 A CN 101744245A CN 200810209694 A CN200810209694 A CN 200810209694A CN 200810209694 A CN200810209694 A CN 200810209694A CN 101744245 A CN101744245 A CN 101744245A
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Abstract
The invention belongs to the field of a high and new technology, in particular to a medicament form of a soft capsule and a preparation method thereof. The invention matches schisandra fruit produced in Great Xingan Mountains and royal jelly reasonably, realizes the polymerization and the tissue regeneration of trophic factors and gives prominence to an additive effect; the medicament form of the soft capsule is prepared by utilizing the technologies of ultrasonic extraction, freeze drying and superfine pulverization and fully extracting and retaining nutritional health-care factors. The preparation method comprises the following steps: (1) taking the royal jelly, defrosting, filtering out the impurities of beeswax and the like, remaining 12kg and preparing into a fine granular state by utilizing the technologies of vacuum freeze drying and superfine pulverization; (2) after selecting the schisandra fruit, removing the impurities and washing, remaining 15kg, carrying out superfine pulverization after carrying out vacuum drying, and extracting effective components by utilizing an ultrasonic extraction technology; and (3) mixing the dry powder of the royal jelly and an extract of the schisandra fruit fully, assisting with 66kg of vegetable oil and 7kg of gelatin, granulating, washing a pill, drying, bottling after passing a test, and boxing to obtain a product.
Description
Technical field
The invention belongs to high-technology field, specifically is a kind of with the Daxing'an Mountainrange real estate fruit of Chinese magnoliavine and royal jelly reasonable compatibility, realizes that the trophic factors polymerization is living new, outstanding additive effect; Utilize vacuum freeze drying, ultra-fine grinding and ultrasonic extraction technology, fully extract and keep the nourishing healthy factor, and make soft capsule dosage form and preparation method thereof.
The raw materials used fruit of Chinese magnoliavine of this product is among the virgin forest from Daxing'an Mountainrange.Here being located between north latitude 50 degree～53 degree, is a natural pure land, and day and night temperature is big, is fit to the growth of the fruit of Chinese magnoliavine.Here vegetation is in great numbers, and species are abundant.On 8.4 ten thousand square kilometres soil, thousands of kinds of wild plants are arranged.
Royal jelly is national standardization agricultural product from a national class agricultural standardization demonstration area.
This products material all meets the production of organic food qualification organization of European Union organic food, processing criterion, is the safe functioning nutraceutical.
Background technology
The fruit of Chinese magnoliavine is commonly called as mountain flower green pepper, sliding weight of steelyard, the medicine fruit of Chinese magnoliavine, face rattan, five plums etc., ancient medical book Cheng Ta Chi Zhu, profound and, can and.Fruit for magnoliaceae schisandra.Perennial fallen leaves liana.Fruit is practised and is claimed " fructus schisandrae ", hyoscine.Ground such as Northeast China, North China all has wild or cultivation.
Schisandra fruit is made Chinese medicine function nourishing generate fluid, the nourshing kidney of astringing the lung, antidiarrheal, puckery essence, is calmed the nerves, and can control diseases such as chronic cough void is breathed heavily, dry is lacked in Tianjin, seminal emission is rushed down for a long time, forgetful insomnia.The pharmacological testing proof can be regulated the excitement and the process of inhibition of central nervous system, promotes body metabolism, regulates the secretion of gastric juice and bile, and rising person has the reduction effect to hepatitis convalescence transaminase.Pericarp and the ripe skin of planting contain lignanoid, are the effective medicinal components of the fruit of Chinese magnoliavine, comprising multiple schizandrin.Seed is fatty, but grease soap system or machine oil.Cauline leaf and seed all can extract aromatic oil.
Royal jelly has another name called bee milk, royal jelly, is the secretion of cultivating young worker bee (nurse honeybee) the pharynx gland of larva in the honeycomb.Be the food of supplying with the larva that will become queen bee.Contain protein, fat, carbohydrate, vitamin A, Cobastab in the royal jelly
1, Cobastab
2, abundant folic acid, pantothenic acid, aliphatic acid and alcohols, also have similar acetylcholine sample material, and the amino acid that needs of multiple human body and bio-hormone etc.
The nutritionist thinks that royal jelly is unique in the world super nutritive food for the human high activity composition of directly taking.The personages of state the world of medicine such as American and Britain, method, moral, meaning, day sum up royal jelly ten large effects:
1, royal jelly contains acetylcholine, can make vegetative nerve recover normal, and is remarkable to treatment cardiovascular disease effect, has the effect of good adjusting blood fat;
2, royal jelly is rich in Cobastab and good protein, particularly contains the strong royal jelly acid of sterilizing power, thereby for controlling cancer good medicine;
3, royal jelly has the effect of the hematopoiesis function of promotion, can increase hemoglobin to developmental children, promotes growth, improves premunition;
4, royal jelly contains pantothenic acid, can improve rheumatism and joint symptom;
5, royal jelly contains para-insulin, and diabetes are had better effects;
6, royal jelly can be strengthened the adrenal cortex function, regulates the human hormone, and brain cell between activation helps treating climacteric disfunction and chronic prostatitis syndrome;
7, royal jelly can strengthen people's basis muscle power, makes the activation of human senility tissue, and clothes back appetite is good, long spirit, and complexion is good;
8, contained peptide of royal jelly and protein-based healthy ingredient can promote intellectual development, thereby take and can improve memory;
9, royal jelly contains proteohormone, and the clothes back helps skin histology functional recovery vigor with the blood circulation whole body, and is obvious to treatment scald effect;
10, royal jelly contains plurality of inorganic salt, can promote glycogen to discharge, and promotes metabolism, thereby can improve looks, and eliminates speckle.
Through scientific research for many years and clinical medicine facts have proved both at home and abroad, royal jelly has peculiar effect to human medical treatment, health care etc., can improve nutrition, additional mentality, raising body immunity, prophylactic treatment cardiovascular and cerebrovascular disease, treatment anaemia, anti-inflammatory, pain relieving, promotion wound healing, pre-anti-cancer, beauty treatment;
In a word, royal jelly, the fruit of Chinese magnoliavine are human important nutrient sources.But generally all be independent use at present, also do not find the composite use of science, therefore, have antifatigue, regulate the royal jelly shizandra berry soft capsule of immunologic function by exploitation, can advance bee product and the composite use of other resource, improve the Science Explorations of health-care effect.
Summary of the invention
Purpose of the present invention is exactly to better meet the demand of society to the nourishing healthy product, solve the dose-effect relationship of royal jelly fruit of Chinese magnoliavine reasonable compatibility, realize that the trophic factors polymerization is living new, outstanding additive effect, and be made into the method that has antifatigue, regulates the healthy food of immunologic function.
Royal jelly shizandra berry soft capsule of the present invention is the dose-effect relationship of a kind of Daxing'an Mountainrange real estate fruit of Chinese magnoliavine and royal jelly reasonable compatibility, realizes that the trophic factors polymerization is living new, outstanding additive effect; Utilize ultrasonic extraction, freeze drying and ultra-fine grinding technology are fully extracted and are kept the nourishing healthy factor, refining having antifatigue, regulating the healthy food of immunologic function of forming.
The preparation method of royal jelly shizandra berry soft capsule of the present invention is:
1, royal jelly extracting thaws, and filters out impurity residue 12kg such as beeswax, the utilization vacuum freeze drying, and the ultra-fine grinding technology is made the fine particle state;
2, the fruit of Chinese magnoliavine is selected, residue 15kg carries out ultra-fine grinding after the vacuum drying after the impurity elimination, cleaning, utilization ultrasonic extraction technology is extracted functional component;
3, royal jelly dried powder and Schisandra chinens P.E are fully mixed, be aided with vegetable oil 66kg, gelatin 7kg granulates, and washes ball, drying, and bottling after the assay was approved, vanning gets product.
This royal jelly capsule is checked through Heilongjiang Province's product quality supervision and inspection two stations, the result is: according to the check down of five tastes subitem of Pharmacopoeia of People's Republic of China, the schizandrin A positive is according to the check down of royal jelly national standard item, 10-hydroxyl-2-decylenic acid content 〉=0.2%.
The specific embodiment
Embodiment 1:
1, royal jelly extracting thaws, and filters out impurity residue 10kg such as beeswax, the utilization vacuum freeze drying, and the ultra-fine grinding technology is made the fine particle state;
2, the fruit of Chinese magnoliavine is selected, residue 17kg carries out ultra-fine grinding after the vacuum drying after the impurity elimination, cleaning, utilization ultrasonic extraction technology is extracted functional component;
3, royal jelly dried powder and Schisandra chinens P.E are fully mixed, be aided with vegetable oil 66kg, gelatin 7kg granulates, and washes ball, drying, and bottling after the assay was approved, vanning gets product.
Embodiment 2:
1, royal jelly extracting thaws, filters out impurity residue 11kg such as beeswax, and utilization vacuum freeze drying and ultra-fine grinding technology are made the fine particle state;
2, the fruit of Chinese magnoliavine is selected, residue 16kg carries out ultra-fine grinding after the vacuum drying after the impurity elimination, cleaning, utilization ultrasonic extraction technology is extracted functional component;
3, royal jelly dried powder and Schisandra chinens P.E are fully mixed, be aided with vegetable oil 66kg, gelatin 7kg granulates, and washes ball, drying, and bottling after the assay was approved, vanning gets product.
Embodiment 3:
1, royal jelly extracting thaws, and filters out impurity residue 12kg such as beeswax, and utilization vacuum freeze drying and ultra-fine grinding technology are made the fine particle state;
2, the fruit of Chinese magnoliavine is selected, residue 15kg carries out ultra-fine grinding after the vacuum drying after the impurity elimination, cleaning, utilization ultrasonic extraction technology is extracted functional component;
3, royal jelly dried powder and Schisandra chinens P.E are carried out fully mixing in the cleaning shop, be aided with vegetable oil 66kg, gelatin 7kg granulates, and washes ball, drying, and bottling after the assay was approved, vanning gets product.
Embodiment 4:
1, royal jelly extracting thaws, and filters out impurity residue 13kg such as beeswax, and utilization vacuum freeze drying and ultra-fine grinding technology are made the fine particle state;
2, the fruit of Chinese magnoliavine is selected, residue 15kg carries out ultra-fine grinding after the vacuum drying after the impurity elimination, cleaning, utilization ultrasonic extraction technology is extracted functional component;
3, royal jelly dried powder and Schisandra chinens P.E are fully mixed, be aided with vegetable oil 65kg, gelatin 7kg granulates, and washes ball, drying, and bottling after the assay was approved, vanning gets product.
Embodiment 5:
1, royal jelly extracting thaws, and filters out impurity residue 14kg such as beeswax, and utilization vacuum freeze drying and ultra-fine grinding technology are made the fine particle state;
2, the fruit of Chinese magnoliavine is selected, residue 14kg carries out ultra-fine grinding after the vacuum drying after the impurity elimination, cleaning, utilization ultrasonic extraction technology is extracted functional component;
3, royal jelly dried powder and Schisandra chinens P.E are fully mixed, be aided with vegetable oil 66kg, gelatin 6kg granulates, and washes ball, drying, and bottling after the assay was approved, vanning gets product.
Embodiment 6:
1, royal jelly extracting thaws, and filters out impurity residue 13kg such as beeswax, and utilization vacuum freeze drying and ultra-fine grinding technology are made the fine particle state;
2, the fruit of Chinese magnoliavine is selected, residue 13kg carries out ultra-fine grinding after the vacuum drying after the impurity elimination, cleaning, utilization ultrasonic extraction technology is extracted functional component;
3, royal jelly dried powder and Schisandra chinens P.E are fully mixed, be aided with vegetable oil 66kg, gelatin 8kg granulates, and washes ball, drying, and bottling after the assay was approved, vanning gets product.
Claims (1)
1. a royal jelly shizandra berry soft capsule is characterized in that the Daxing'an Mountainrange real estate fruit of Chinese magnoliavine and royal jelly reasonable compatibility, realizes that the trophic factors polymerization is living new, outstanding additive effect; Utilize freeze drying, ultra-fine grinding and ultrasonic extraction technology are fully extracted and are kept the nourishing healthy factor, and make soft capsule dosage form and preparation method thereof.The schizandrin A positive in the product, 10-hydroxyl-2-decylenic acid content 〉=0.2%.The preparation method of this kind royal jelly shizandra berry soft capsule is:
1, royal jelly extracting thaws, and filters out impurity residue 12kg such as beeswax, the utilization vacuum freeze drying, and the ultra-fine grinding technology is made the fine particle state;
2, the fruit of Chinese magnoliavine is selected, residue 15kg carries out ultra-fine grinding after the vacuum drying after the impurity elimination, cleaning, utilization ultrasonic extraction technology is extracted functional component;
3, royal jelly dried powder and Schisandra chinens P.E are fully mixed, be aided with vegetable oil 66kg, gelatin 7kg granulates, and washes ball, drying, and bottling after the assay was approved, vanning gets product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810209694A CN101744245A (en) | 2008-12-12 | 2008-12-12 | Soft capsule of royal jelly and schisandra fruit and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810209694A CN101744245A (en) | 2008-12-12 | 2008-12-12 | Soft capsule of royal jelly and schisandra fruit and preparation method thereof |
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| Publication Number | Publication Date |
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| CN101744245A true CN101744245A (en) | 2010-06-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200810209694A Pending CN101744245A (en) | 2008-12-12 | 2008-12-12 | Soft capsule of royal jelly and schisandra fruit and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106174419A (en) * | 2016-07-23 | 2016-12-07 | 洪雅县和鑫农业科技发展有限公司 | A kind of Pericarpium Zanthoxyli beans manufacture method |
| CN108245500A (en) * | 2018-01-12 | 2018-07-06 | 上海中医药大学 | Royal jelly acid is preparing the purposes in treating the raised disease medicine of activity of adenosine deaminase |
| CN111011793A (en) * | 2019-12-16 | 2020-04-17 | 天津星宇航天生物科技有限公司 | Preparation method of aerospace-grade royal jelly capable of rapidly recovering physical function |
-
2008
- 2008-12-12 CN CN200810209694A patent/CN101744245A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106174419A (en) * | 2016-07-23 | 2016-12-07 | 洪雅县和鑫农业科技发展有限公司 | A kind of Pericarpium Zanthoxyli beans manufacture method |
| CN108245500A (en) * | 2018-01-12 | 2018-07-06 | 上海中医药大学 | Royal jelly acid is preparing the purposes in treating the raised disease medicine of activity of adenosine deaminase |
| CN108245500B (en) * | 2018-01-12 | 2020-02-14 | 上海中医药大学 | Application of royal jelly acid in preparing medicine for treating diseases with increased adenosine deaminase activity |
| CN111011793A (en) * | 2019-12-16 | 2020-04-17 | 天津星宇航天生物科技有限公司 | Preparation method of aerospace-grade royal jelly capable of rapidly recovering physical function |
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Application publication date: 20100623 |