CN102349651A - Health care food with functions of enhancing immunity and easing fatigue and preparation method thereof - Google Patents
Health care food with functions of enhancing immunity and easing fatigue and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a health care food with the functions of enhancing the immunity and easing the fatigue and a preparation method thereof. The health care food takes a dendrobium officinale composition as an active ingredient and is prepared into a preparation formulation which is suitable for taking, wherein the dendrobium officinale composition comprises the raw materials prepared by dendrobium officinale, rhodiola rosea and barbary wolfberry fruit according to the weight ratio of 0.15-15: 0.15-15: 1; and the preparation method sequentially comprises the following steps: adding water for decoction and extraction for 2-3 times, filtering extraction solution, merging, concentrating into liquid extract, and spray-drying to get liquid extract powder with the water content of below 5% by weight, and the preparation formulation which is suitable for taking can be tablets, granules, capsules or powder. The health care food is particularly suitable for people who are low in immunity and easy to fatigue, high in safety, exact in efficacy and lower in cost.
Description
Technical field
the invention belongs to health food technology field, particularly a kind of health food with enhance immunity power and function of alleviating fatigue and preparation method thereof.
Background technology
are with the quickening of rhythm of life; The modern often receives the pressure from aspects such as society, work and families; Add environmental pollution, body regular meeting is in health status, is embodied in hypoimmunity, weak, dizzy, failure of memory, insomnia etc.The data that The World Health Organization (WHO) announces show that the whole world adult 1/10 is in sub-health state.Inferior health is between intermediateness healthy and disease, only is the disorder of function, does not have organic disease, but if untimely correction, various diseases will be comed one after another.Medical expert's warp is discovered for many years, the change of life style now, and the pickuping food nutrient is single, and functional components lacks, and is one of reason that causes the rising of the malignant disease incidence of disease.Therefore, when advocating the diet style of back to nature, life style, the intake of suitably strengthening the health food that is rich in the related functionality composition seems particularly important.In recent years, the functional component of scientific research discovery comprises: active compound sugar, active polysaccharide, active grease, biological anti-oxidant, active peptides, lactic acid bacteria and other active components.Health food can improve the physiological function and the immunity of organisms of sub-health population, thereby gets well state.Normal for physiological function, as to want maintaining healthy or reduce certain disease risks people, " health food " is a kind of nutriment; Unusual for physiological function, as to be in sub-health state people, " health food " can be regulated certain physiological function to improve health.
dendrobium candidum is a rare Chinese medicine commonly used, and applicating history is long, in Shennong's Herbal, classifies as top gradely, has the effect that nourishing Yin and clearing heat, the beneficial stomach that promotes the production of body fluid, moistening lung quench the thirst, wet one's whistle and make eye bright, promote longevity." the reinforcing yin essence benefit is smart for the Compendium of Material Medica record stem of noble dendrobium.Obey thick stomach for a long time.Never sufficient in the benefit, flat stomach Qi, longue meat ... Make light of one's life by commiting suicide and prolong life." Tiepi Fengdou is the dry stem of dendrobium candidum (Dendrobium officinale Kimura et Migo), gather March in November to next year, removes impurity; cut off the part fibrous root; the limit heating edge is twisted into spirality or spring-like, oven dry, and dry product is practised and is claimed " Tiepi Fengdou " (earrings dendrobium).Be generally 2～6 liras, the long 3.5～8cm in the stretching back of stem, diameter 0.2～0.4cm.Surface yellow green or have a little golden yellow has thin vertical wrinkle, joint obviously, visible sometimes residual canescence leaf sheath on the joint; The short hairs root that the visible basal part of stem of one end stays.Matter is solid, frangible, and section is smooth, and canescence is omited the cutin shape to celadon.Gas is little, and is lightly seasoned, and that chews has a stickiness.
are that the health food of primary raw material has huge market prospects with the dendrobium candidum, have very good curative effect for hypoimmunity, fatiguability crowd.Over nearly 10 years, dendrobium candidum class health food obtains exploitation in succession, and product emerges in an endless stream, and has formed the bigger market share, especially in the health care series products of enhance immunity power, comes out top.The health-care effect of dendrobium candidum class health food particularly formulation, prescription and the production technology of effect and the food of its enhance immunity power and alleviating fatigue is closely related.Seeing that the cost of dendrobium candidum health food is generally higher in the market, developing low-cost, the dendrobium candidum health food is significant safely and efficiently.
Summary of the invention
technical problem to be solved by this invention provides a kind of health food with enhance immunity power and function of alleviating fatigue, and it is safe and efficient and cost is lower.
the present invention also will provide a kind of preparation method with health food of enhance immunity power and function of alleviating fatigue simultaneously, and this method is simple, and cost is low, and the gained health food is safe and efficient.
For solving above technical problem, a kind of technical scheme that the present invention takes:
a kind of health food with enhance immunity power and function of alleviating fatigue; This health food is for being the formulation that is suitable for taking that active ingredient is processed with the Tiepi Fengdou composition; Said Tiepi Fengdou composition is the raw material that Tiepi Fengdou, rhodiola root, the fruit of Chinese wolfberry are made into by weight 0.15～15:0.15～15:1; Extract 2～3 times through boiling successively; Extracting liquid filtering; Merge; Be concentrated into medicinal extract; The moisture that spray-drying obtains is lower than the extract powder of 5wt%, and the said formulation that is suitable for taking is tablet, granule, capsule or powder.
are according to further embodiment of the present invention: before boiling is extracted, said Tiepi Fengdou as raw material is cut into the segment of 2～3 centimeter length.When boiling was extracted, the addition of water was preferably 8～12 times of raw material weight, and decocting time is preferably 2～3 hours.Preferably, concentrating the relative density of gained medicinal extract under 60 ℃ is 1.05～1.10.
according to a preferred aspect of the present invention, said Tiepi Fengdou as raw material, rhodiola root and fruit of Chinese wolfberry three's weight ratio is 1～2:1～2:1.More preferably, the weight ratio as Tiepi Fengdou, rhodiola root and the fruit of Chinese wolfberry three of raw material is 1.4～1.6:1.4～1.6:1.Most preferably, the weight ratio of Tiepi Fengdou, rhodiola root and the fruit of Chinese wolfberry is 1.5:1.5:1.
The another technical scheme that the present invention takes is: a kind of preparation method of the above-mentioned health food with enhance immunity power and function of alleviating fatigue, it comprises the steps:
(1), get Tiepi Fengdou, be cut into the segment of 2～3 centimeter length, then with Tiepi Fengdou segment, rhodiola root and fruit of Chinese wolfberry water boiling and extraction, extract 2～3 times;
(2), with all extracting liquid filterings of step (1), merging filtrate is concentrated into medicinal extract;
(3), make the spray-dried acquisition water content of step (2) gained medicinal extract be no more than the extract powder of 5wt%;
(4), said extract powder is processed the formulation that is suitable for taking by routine techniques.
are according to further preferred version of the present invention: in the step (1), when said boiling was extracted, the addition of water was 8～12 times of raw material weight.Decocting time is 2～3 hours; In the step (2), the relative density of said concentrated gained medicinal extract under 60 ℃ is 1.05～1.10.In the step (3), said spray-drying control parameter is following: 18000 rev/mins～25000 rev/mins of rotating speeds, 180 ℃～190 ℃ of EATs, 85 ℃～95 ℃ of leaving air temps.
Capsule according to invention, is especially preferably processed with health food in
.At this moment; It is that 0.5%～1.5% superfine silica gel powder of said extract powder weight mixes that above-mentioned step (4) can be implemented extract powder and weight through following process; Be filled into the pharmagel hard shell capsules through automatic capsule filling machine and promptly get, wherein the dipping powder content is 0.3～0.5g/ capsules in the capsule.Employed pharmagel hard shell capsules preferably meets the capsulae vacuus that GB13731-1992 pharmagel hard shell capsules requires.
according to the present invention, all is known as Tiepi Fengdou, rhodiola root, the fruit of Chinese wolfberry of raw material, can be through being purchased acquisition.
Because the employing of technique scheme, the present invention compared with prior art has the following advantages:
health food of the present invention is the basis with the traditional Chinese medicine theory, adopts modern science and technology to be prepared from.Tiepi Fengdou is sweet light cold and cool, goes into lung, stomach, kidney three warps, and ability clearing lung-heat heat, nourishing stomach-YIN, kidney tonifying essence play the effect of " the tonifying five zang organs consumptive disease is thin thin, reinforcing yin essence " in this prescription.Rhodiola root has the merit of blood-enrich, is apt to moistening lung, ability kidney tonifying, regulates the flow of vital energy and nourish blood, the effect that can assist Tiepi Fengdou performance qi-restoratives to set upright.Assistant is with the fruit of Chinese wolfberry, and is nourishing liver and kidney, benefiting shrewd head, and all article are harmonious, and not only mend but also clear, mend and oiliness, play the merit of " promoting production of body fluid and benefiting qi enriching yin, nourishing the stomach clearing lung-heat kidney tonifying " altogether, can beneficial gas qi-restoratives, strengthening vital QI to eliminate pathogenic factors.Hinder so can cure mainly pyreticosis Tianjin, functional activities of the body fluid is not enough, and the lung stomach is weak, damage of kidney-essence, and disease is seen fire excess from yin deficiency, the dry polydipsia, lassitude hypodynamia, food is few retches, and muscles and bones is withered soft, and blurred vision is not clear, frequent urination, red tongue with a little fluid person.Prove through animal experiment, health food safety non-toxic of the present invention, and function of enhancing immunity is remarkably productive.In addition, cost of material of the present invention and production cost are relatively low.
The specific embodiment
are done further detailed explanation below in conjunction with concrete embodiment to the present invention, but the invention is not restricted to following examples.
Embodiment 1
Present embodiment provides a kind of health-caring capsule with enhance immunity power and function of alleviating fatigue, and it prepares through following steps:
(1), get Tiepi Fengdou medicinal material 300g, be cut into the segment of 2～3cm with medicine cutter; Then get Tiepi Fengdou segment 300g, rhodiola root 300g and fruit of Chinese wolfberry 200g, with water boiling and extraction 3 times, each 2.5 hours;
(2), step (1) gained extract is all filtered, merging filtrate is concentrated into relative density and is 1.08～1.10 medicinal extract;
(3), the spray-dried extract powder that obtains, the spray-drying condition is: 20000 rev/mins of rotating speeds, 185 ℃ of EATs, 90 ℃ of leaving air temps, gained extract powder water content must not surpass 5%.
(4), the extract powder 240g that takes by weighing the said extracted gained add 2.4g superfine silica gel powder (increase mobile with); The automatic capsule filling machine of warp is filled into and meets GB13731-1992 pharmagel hard shell capsules (No. 0); The loading amount minus deviation is controlled at below 8%; The capsule that installs polishes in sanding machine; Reject damaged capsule, promptly get.Suit hypoimmunity, fatiguability person of product of the present invention taken, and eating method is each 2 times, each 3.
Embodiment 2
Present embodiment provides a kind of health-caring capsule with enhance immunity power and function of alleviating fatigue, and it prepares through following steps:
(1), get Tiepi Fengdou medicinal material 50g, be cut into the segment of 2～3cm with medicine cutter; Then get Tiepi Fengdou segment 300g, rhodiola root 300g and fruit of Chinese wolfberry 100g, with water boiling and extraction 3 times, each 2.5 hours;
(2), step (1) gained extract is all filtered, merging filtrate is concentrated into relative density and is 1.08～1.10 medicinal extract;
(3), the spray-dried extract powder that obtains, the spray-drying condition is: 20000 rev/mins of rotating speeds, 185 ℃ of EATs, 90 ℃ of leaving air temps, gained extract powder water content must not surpass 5%.
(4), the extract powder 210g that takes by weighing the said extracted gained add 2.1g superfine silica gel powder (increase mobile with); The automatic capsule filling machine of warp is filled into and meets GB13731-1992 pharmagel hard shell capsules (No. 0); The loading amount minus deviation is controlled at below 8%; The capsule that installs polishes in sanding machine; Reject damaged capsule, promptly get.Suit hypoimmunity, fatiguability person of product of the present invention taken, and eating method is each 2 times, each 3.
Embodiment 3
Present embodiment provides a kind of health-caring capsule with enhance immunity power and function of alleviating fatigue, and it prepares through following steps:
(1), get Tiepi Fengdou medicinal material 50g, be cut into the segment of 2～3cm with medicine cutter; Then get Tiepi Fengdou segment 300g, rhodiola root 300g and fruit of Chinese wolfberry 300g, with water boiling and extraction 3 times, each 2.5 hours;
(2), step (1) gained extract is all filtered, merging filtrate is concentrated into relative density and is 1.08～1.10 medicinal extract;
(3), the spray-dried extract powder that obtains, the spray-drying condition is: 20000 rev/mins of rotating speeds, 185 ℃ of EATs, 90 ℃ of leaving air temps, gained extract powder water content must not surpass 5%.
(4), the extract powder 270g that takes by weighing the said extracted gained add 2.7g superfine silica gel powder (increase mobile with); The automatic capsule filling machine of warp is filled into and meets GB13731-1992 pharmagel hard shell capsules (No. 0); The loading amount minus deviation is controlled at below 8%; The capsule that installs polishes in sanding machine; Reject damaged capsule, promptly get.Suit hypoimmunity, fatiguability person of product of the present invention taken, and eating method is each 2 times, each 3.
Embodiment 4
Present embodiment provides a kind of health care sheet with enhance immunity power and function of alleviating fatigue, and it prepares through following steps:
(1), get Tiepi Fengdou medicinal material 300g, be cut into the segment of 2～3cm with medicine cutter; Then get Tiepi Fengdou segment 300g, rhodiola root 300g and fruit of Chinese wolfberry 200g, with water boiling and extraction 3 times, each 2.5 hours;
(2), step (1) gained extract is all filtered, merging filtrate is concentrated into relative density and is 1.08～1.10 medicinal extract;
(3), the spray-dried extract powder that obtains, the spray-drying condition is: 20000 rev/mins of rotating speeds, 185 ℃ of EATs, 90 ℃ of leaving air temps, gained extract powder water content must not surpass 5%.
(4), extract powder of getting the said extracted gained, L-HPC 10g, microcrystalline cellulose 15g pulverized 100 mesh sieves respectively; The method of progressively increasing by equivalent is put in the blender and is mixed; Put in the fluidised bed granulator and granulate; Pellet moisture is less than 5%; The whole grain of 30 mesh sieves; Add dolomol 3g, compressing tablet promptly gets behind the mixing.
Embodiment 5
Present embodiment provides a kind of health care particle with enhance immunity power and function of alleviating fatigue, and it prepares through following steps:
(1), get Tiepi Fengdou medicinal material 300g, be cut into the segment of 2～3cm with medicine cutter; Then get Tiepi Fengdou segment 300g, rhodiola root 300g and fruit of Chinese wolfberry 200g, with water boiling and extraction 3 times, each 2.5 hours;
(2), step (1) gained extract is all filtered, merging filtrate is concentrated into relative density and is 1.08～1.10 medicinal extract;
(3), the spray-dried extract powder that obtains, the spray-drying condition is: 20000 rev/mins of rotating speeds, 185 ℃ of EATs, 90 ℃ of leaving air temps, gained extract powder water content must not surpass 5%.
(4), get said extracted gained extract powder, dextrin 480g pulverized 100 mesh sieves respectively, put in the blender to mix, put in the fluidised bed granulator and granulate; Pellet moisture is less than 5%; The whole grain of 14 mesh sieves is crossed 60 mesh sieves sieve and is removed fine powder, divides packing promptly to get.
With embodiment 1 to 3 gained health-caring capsule is that example is carried out animal experiment, specific as follows:
1, confirm safety non-toxic through animal experiment, experimental result and conclusion are following:
1. acute toxicity testing shows: according to acute toxicity dose grading standard, and true border avirulence level;
2. bone marrow cell micronucleus test, sperm malformation test, Salmonella reversion test result are negative;
are 30 days feeding trials 3.: the animal used as test growing state is good, hematological examination, and biochemical analysis, main dirty body is histological examination result when compare with control group, and all no abnormality seen proves safety non-toxic of the present invention.
2, confirm to have function of enhancing immunity through animal experiment, experimental result and conclusion are following:
per os gives the health-caring capsule 30 days of the high, medium and low dose groups of mouse; High dose group can increase mouse delayed allergy ability, lymphocyte transformation ability, serum HD50 value, antibody-producting cell number, with control group significant difference (P< is arranged relatively; 0.05 or P<0.01); Middle and high dose groups can increase the NK cytoactive, with control group significant difference (P< is arranged relatively; 0.05); Weight of mice, spleen/body weight ratio, thymus gland/body weight ratio, mouse monokaryon-macrophage carbon are cleaned up ability to each dose groups and macrophage phagocytic chicken red blood cell ability does not have obvious influence (P>0.05).
The dosage range of
above-mentioned high dose, middle dosage and low dosage is respectively 0.8～1.2g/kgbw, 0.4～0.6g/kgbw, 0.1～0.3 g/kgbw (down together).
3, confirm to have the alleviating physical fatigue function through animal experiment, experimental result and conclusion are following:
per os give the high, medium and low dose groups of mouse according to source board Tiepi Fengdou red-spotted stonecrop capsule 30 days; High dose group can obviously prolong the swimming with a load attached to the body time of mouse; Serum urea level behind the reduction mouse movement; Increase Mouse Liver glycogen storage level, significant difference (P< is relatively arranged with control group; 0.05 or P< 0.01); Each dose groups is not seen obvious influence (P> to mouse blood lactic acid TG-AUC; 0.05).
The foregoing description only is explanation technical conceive of the present invention and characteristics; Its purpose is to allow the personage who is familiar with this technology can understand content of the present invention and enforcement according to this; Can not limit protection scope of the present invention with this; All equivalences that spirit is done according to the present invention change or modify, and all should be encompassed within protection scope of the present invention
Claims (10)
1. health food with enhance immunity power and function of alleviating fatigue; It is characterized in that: said health food is for being the formulation that is suitable for taking that active ingredient is processed with the Tiepi Fengdou composition; Said Tiepi Fengdou composition is the raw material that Tiepi Fengdou, rhodiola root, the fruit of Chinese wolfberry are made into by weight 0.15～15:0.15～15:1; Extract 2～3 times through boiling successively; Extracting liquid filtering; Merge; Be concentrated into medicinal extract; The moisture that spray-drying obtains is lower than the extract powder of 5wt%, and the said formulation that is suitable for taking is tablet, granule, capsule or powder.
2. the health food with enhance immunity power and function of alleviating fatigue according to claim 1 is characterized in that: before boiling is extracted, said Tiepi Fengdou as raw material is cut into the segment of 2～3 centimeter length.
3. the health food with enhance immunity power and function of alleviating fatigue according to claim 1 is characterized in that: when said boiling was extracted, the addition of water was 8～12 times of raw material weight, and decocting time is 2～3 hours.
4. the health food with enhance immunity power and function of alleviating fatigue according to claim 1 is characterized in that: the relative density of said concentrated gained medicinal extract under 60 ℃ is 1.05～1.10.
5. according to the described health food with enhance immunity power and function of alleviating fatigue of each claim in the claim 1 to 4, it is characterized in that: said Tiepi Fengdou as raw material, rhodiola root and fruit of Chinese wolfberry three's weight ratio is 1～2:1～2:1.
6. the health food with enhance immunity power and function of alleviating fatigue according to claim 5 is characterized in that: said Tiepi Fengdou as raw material, rhodiola root and fruit of Chinese wolfberry three's weight ratio is 1.4～1.6:1.4～1.6:1.
7. the described preparation method with health food of enhance immunity power and function of alleviating fatigue of claim 1 is characterized in that: comprise the steps:
(1), get Tiepi Fengdou, be cut into the segment of 2～3 centimeter length, then with Tiepi Fengdou segment, rhodiola root and fruit of Chinese wolfberry water boiling and extraction, extract 2～3 times;
(2), with all extracting liquid filterings of step (1), merging filtrate is concentrated into medicinal extract;
(3), make the spray-dried acquisition water content of step (2) gained medicinal extract be no more than the extract powder of 5wt%;
(4), said extract powder is processed the formulation that is suitable for taking by routine techniques.
8. preparation method according to claim 7 is characterized in that: in the step (1), when said boiling was extracted, the addition of water was 8～12 times of raw material weight, and decocting time is 2～3 hours; In the step (2), the relative density of said concentrated gained medicinal extract under 60 ℃ is 1.05～1.10.
9. preparation method according to claim 7 is characterized in that: in the step (3), said spray-drying control parameter is following: 18000 rev/mins～25000 rev/mins of rotating speeds, 180 ℃～190 ℃ of EATs, 85 ℃～95 ℃ of leaving air temps.
10. preparation method according to claim 7; It is characterized in that: described formulation is a capsule; The detailed process of step (4) is: with extract powder and weight is that 0.5%～1.5% superfine silica gel powder of said extract powder weight mixes; Be filled into the pharmagel hard shell capsules through automatic capsule filling machine; Promptly get, wherein the dipping powder content is 0.3～0.5g/ capsules in the capsule.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784754A (en) * | 2014-01-22 | 2014-05-14 | 安徽思康生物科技有限公司 | Capsules with effects of tonifying kidney and strengthening yang and preparation method thereof |
| CN104367834A (en) * | 2014-11-13 | 2015-02-25 | 成都华熹科技有限公司 | Traditional Chinese medicine composition containing ginkgo leaves and used for improving immunity |
| CN105249456A (en) * | 2015-10-28 | 2016-01-20 | 青海尤尼克生物技术有限公司 | Dendrobium health-care composition |
| CN106177504A (en) * | 2016-08-27 | 2016-12-07 | 桂林七星粉业有限责任公司 | A kind of processing technique of the Herba Dendrobii health care tablet of enhancing immunity |
| CN106889609A (en) * | 2017-01-09 | 2017-06-27 | 安徽中升生物科技有限公司 | A kind of health instant powder with the stem of noble dendrobium as main material |
| CN108567911A (en) * | 2018-05-21 | 2018-09-25 | 马展飞 | A kind of Chinese medicine preparation of nourishing nourishing the stomach |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101485458A (en) * | 2009-02-16 | 2009-07-22 | 钱志明 | Health product containing dendrobium, ginseng and matrimony vine |
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2011
- 2011-10-28 CN CN2011103333205A patent/CN102349651B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101485458A (en) * | 2009-02-16 | 2009-07-22 | 钱志明 | Health product containing dendrobium, ginseng and matrimony vine |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784754A (en) * | 2014-01-22 | 2014-05-14 | 安徽思康生物科技有限公司 | Capsules with effects of tonifying kidney and strengthening yang and preparation method thereof |
| CN104367834A (en) * | 2014-11-13 | 2015-02-25 | 成都华熹科技有限公司 | Traditional Chinese medicine composition containing ginkgo leaves and used for improving immunity |
| CN105249456A (en) * | 2015-10-28 | 2016-01-20 | 青海尤尼克生物技术有限公司 | Dendrobium health-care composition |
| CN106177504A (en) * | 2016-08-27 | 2016-12-07 | 桂林七星粉业有限责任公司 | A kind of processing technique of the Herba Dendrobii health care tablet of enhancing immunity |
| CN106889609A (en) * | 2017-01-09 | 2017-06-27 | 安徽中升生物科技有限公司 | A kind of health instant powder with the stem of noble dendrobium as main material |
| CN108567911A (en) * | 2018-05-21 | 2018-09-25 | 马展飞 | A kind of Chinese medicine preparation of nourishing nourishing the stomach |
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| CN102349651B (en) | 2013-04-24 |
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Address after: Songling town of Wujiang city Suzhou city Jiangsu province 215222 split eight Xitang Street Community Applicant after: Suzhou Shenyuan Biotechnology Co., Ltd. Address before: Songling town of Wujiang city Suzhou city Jiangsu province 215222 split eight Xitang Street Community Applicant before: Suzhou Shenyuan Biotechnology Co., Ltd. |
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Application publication date: 20120215 Assignee: Suzhou Yuan Yuan medicinal plant development Co., Ltd. Assignor: Suzhou Shenyuan Biotechnology Co., Ltd. Contract record no.: 2014320010147 Denomination of invention: Health care food with functions of enhancing immunity and easing fatigue and preparation method thereof Granted publication date: 20130424 License type: Common License Record date: 20140813 |
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Inventor after: He Yunfang Inventor after: Teng Shiyuan Inventor after: Shi Jiqing Inventor after: Zhang Ping Inventor after: Zhao Feng Inventor after: Sun Hongjie Inventor before: Teng Shiyuan Inventor before: Shi Jiqing Inventor before: He Yunfang Inventor before: Zhang Ping Inventor before: Zhao Feng Inventor before: Sun Hongjie |