CN101711236B - 表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物 - Google Patents

表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物 Download PDF

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CN101711236B
CN101711236B CN2008800175988A CN200880017598A CN101711236B CN 101711236 B CN101711236 B CN 101711236B CN 2008800175988 A CN2008800175988 A CN 2008800175988A CN 200880017598 A CN200880017598 A CN 200880017598A CN 101711236 B CN101711236 B CN 101711236B
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pharmaceutical composition
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CN101711236A (zh
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H·V·维克斯特罗姆
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Teva Pharmaceuticals International GmbH
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    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide
    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/34—Tobacco-abuse
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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CN2008800175988A 2007-04-12 2008-04-11 表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物 Expired - Fee Related CN101711236B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0700893-1 2007-04-12
SE0700893 2007-04-12
PCT/SE2008/050414 WO2008127188A1 (en) 2007-04-12 2008-04-11 N-oxide and/or di-n-oxide derivatives of dopamine receptor stabilizers/modulators displaying improved cardiovascular side-effects profiles

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CN101711236A CN101711236A (zh) 2010-05-19
CN101711236B true CN101711236B (zh) 2012-10-31

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CN2008800175988A Expired - Fee Related CN101711236B (zh) 2007-04-12 2008-04-11 表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物

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US (1) US9139525B2 (OSRAM)
EP (1) EP2146961B1 (OSRAM)
JP (1) JP5393654B2 (OSRAM)
CN (1) CN101711236B (OSRAM)
AU (1) AU2008239841B2 (OSRAM)
BR (1) BRPI0810161A2 (OSRAM)
CA (1) CA2683719C (OSRAM)
CY (1) CY1115337T1 (OSRAM)
DK (1) DK2146961T3 (OSRAM)
ES (1) ES2458592T3 (OSRAM)
HR (1) HRP20140380T1 (OSRAM)
IL (1) IL201401A (OSRAM)
MX (1) MX2009011020A (OSRAM)
NZ (1) NZ580856A (OSRAM)
PL (1) PL2146961T3 (OSRAM)
PT (1) PT2146961E (OSRAM)
RU (1) RU2470013C2 (OSRAM)
SI (1) SI2146961T1 (OSRAM)
WO (1) WO2008127188A1 (OSRAM)

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UA122999C2 (uk) 2013-06-21 2021-02-03 Прайлінія Н'Юротерапьютікс Лтд. Застосування придопідину для лікування хвороби гантінгтона
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TW201613859A (en) * 2014-06-30 2016-04-16 Teva Pharma Analogs of PRIDOPIDINE, their preparation and use
MX2017008136A (es) 2014-12-22 2018-03-06 Teva Pharmaceuticals Int Gmbh Sal de l-tartrato de pridopidina.
US11471449B2 (en) 2015-02-25 2022-10-18 Prilenia Neurotherapeutics Ltd. Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
MX378579B (es) 2015-02-25 2025-03-11 Prilenia Neurotherapeutics Ltd Uso de pridopidina para mejorar la funcion cognitiva y para tratamiento de enfermedad de alzheimer.
AR105434A1 (es) 2015-07-22 2017-10-04 Teva Pharmaceuticals Int Gmbh Proceso para preparar pridopidina
WO2017147366A1 (en) 2016-02-24 2017-08-31 Teva Pharmaceuticals International Gmbh Treatment of neurodegenerative eye disease using pridopidine
FI3504187T3 (fi) 2016-08-24 2025-04-05 Prilenia Neurotherapeutics Ltd Pridopidiinin käyttö toiminnallisen heikkenemisen hoitoa varten
AU2017315781B2 (en) 2016-08-24 2021-01-28 Prilenia Neurotherapeutics Ltd Use of pridopidine for treating dystonias
US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
PL3570940T3 (pl) 2017-01-20 2024-06-17 Prilenia Neurotherapeutics Ltd. Pridopidyna do zastosowania w leczeniu zespołu łamliwego chromosomu x
LT4154882T (lt) 2017-08-14 2025-11-25 Amiotrofinės lateralinės sklerozės gydymas pridopidinu
CA3073568A1 (en) 2017-08-30 2019-03-07 Prilenia Neurotherapeutics Ltd. High concentration dosage forms of pridopidine
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MX2009011020A (es) 2009-10-30
DK2146961T3 (da) 2014-04-28
JP2010523651A (ja) 2010-07-15
NZ580856A (en) 2011-11-25
CY1115337T1 (el) 2017-01-04
ES2458592T3 (es) 2014-05-06
EP2146961A4 (en) 2011-08-03
WO2008127188A1 (en) 2008-10-23
US9139525B2 (en) 2015-09-22
PT2146961E (pt) 2014-04-30
BRPI0810161A2 (pt) 2014-12-30
PL2146961T3 (pl) 2014-09-30
JP5393654B2 (ja) 2014-01-22
SI2146961T1 (sl) 2014-08-29
EP2146961A1 (en) 2010-01-27
RU2009141300A (ru) 2011-05-20
AU2008239841A1 (en) 2008-10-23
AU2008239841B2 (en) 2013-07-18
IL201401A (en) 2015-10-29
CN101711236A (zh) 2010-05-19
CA2683719A1 (en) 2008-10-23
RU2470013C2 (ru) 2012-12-20
EP2146961B1 (en) 2014-01-29
HRP20140380T1 (hr) 2014-08-15
CA2683719C (en) 2015-07-14
IL201401A0 (en) 2010-05-31
US20100105736A1 (en) 2010-04-29

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