CN101668865B - 与心血管疾病相关联的遗传易感性变体 - Google Patents

与心血管疾病相关联的遗传易感性变体 Download PDF

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Publication number
CN101668865B
CN101668865B CN200880011908.5A CN200880011908A CN101668865B CN 101668865 B CN101668865 B CN 101668865B CN 200880011908 A CN200880011908 A CN 200880011908A CN 101668865 B CN101668865 B CN 101668865B
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allele
risk
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cardiovascular disease
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CN101668865A (zh
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安娜·海尔格多蒂尔
古德玛尔·索尔莱夫松
安德烈·马诺列斯库
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Decode Genetics ehf
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN200880011908.5A 2007-02-21 2008-02-21 与心血管疾病相关联的遗传易感性变体 Expired - Fee Related CN101668865B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
IS8613 2007-02-21
IS8613 2007-02-21
IS8640 2007-04-30
IS8640 2007-04-30
IS8701 2007-12-21
IS8701 2007-12-21
PCT/IS2008/000007 WO2008102380A1 (en) 2007-02-21 2008-02-21 Genetic susceptibility variants associated with cardiovascular disease

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CN101668865A CN101668865A (zh) 2010-03-10
CN101668865B true CN101668865B (zh) 2015-05-06

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US (2) US9617597B2 (https=)
EP (2) EP2115172A1 (https=)
JP (1) JP5646179B2 (https=)
KR (1) KR101571523B1 (https=)
CN (1) CN101668865B (https=)
AU (1) AU2008218542B2 (https=)
BR (1) BRPI0807927A2 (https=)
CA (1) CA2679581C (https=)
DK (1) DK2471954T3 (https=)
EA (1) EA022610B1 (https=)
HU (1) HUE030996T2 (https=)
IL (1) IL200453A (https=)
MX (1) MX2009008878A (https=)
NZ (1) NZ579445A (https=)
SG (1) SG178811A1 (https=)
WO (1) WO2008102380A1 (https=)

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CN103038352B (zh) * 2010-06-15 2015-12-16 萨拉基尼克有限公司 用于增强基因表达的新型基因间元件
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WO2012012693A2 (en) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Methods for detecting signatures of disease or conditions in bodily fluids
AU2011280997A1 (en) 2010-07-23 2013-02-28 President And Fellows Of Harvard College Methods of detecting autoimmune or immune-related diseases or conditions
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KR102158714B1 (ko) * 2019-04-03 2020-09-22 한림대학교 산학협력단 Tcf24 유전자의 단일염기다형성을 포함하는 뇌동맥류 진단용 snp 마커
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KR102344173B1 (ko) * 2021-05-03 2021-12-29 주식회사 바이오에이지 임상 및 유전변이 정보를 통합한 한국인 관상동맥 질환 예측 방법 및 관련 검사추천방법
KR102366097B1 (ko) * 2021-05-03 2022-02-23 주식회사 바이오에이지 임상 및 유전변이 정보를 통합한 한국인 뇌혈관 질환 예측 방법 및 관련 검사추천방법
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SG178811A1 (en) 2012-03-29
US20100068705A1 (en) 2010-03-18
EP2471954B1 (en) 2016-08-24
EA200970781A1 (ru) 2010-04-30
KR101571523B1 (ko) 2015-11-24
JP5646179B2 (ja) 2014-12-24
WO2008102380A1 (en) 2008-08-28
US20120208709A1 (en) 2012-08-16
CA2679581C (en) 2020-12-22
KR20090117896A (ko) 2009-11-13
HUE030996T2 (en) 2017-06-28
MX2009008878A (es) 2009-08-28
EA022610B1 (ru) 2016-02-29
EP2471954A1 (en) 2012-07-04
DK2471954T3 (en) 2016-09-12
AU2008218542A1 (en) 2008-08-28
NZ579445A (en) 2012-02-24
IL200453A (en) 2014-12-31
JP2010518848A (ja) 2010-06-03
US9617597B2 (en) 2017-04-11
EP2115172A1 (en) 2009-11-11
CA2679581A1 (en) 2008-08-28
BRPI0807927A2 (pt) 2014-06-24
AU2008218542B2 (en) 2014-06-26
CN101668865A (zh) 2010-03-10
IL200453A0 (en) 2010-04-29

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